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    • 5. 发明申请
    • IMPLANTABLE ELECTRODES COMPRISING MECHANICALLY ANCHORED BIOCOMPATIBLE HYDROGELS
    • 包含机械固定的生物相容性水凝胶的可植入电极
    • WO2018089975A1
    • 2018-05-17
    • PCT/US2017/061461
    • 2017-11-14
    • VERILY LIFE SCIENCES LLC
    • YAO, HuanfenKAM, KimberlyOTTS, Daniel
    • A61N1/05
    • A61B5/6846A61B5/05A61B2562/046A61B2562/125A61N1/05A61N1/0526A61N1/0541A61N1/0553
    • Biomaterials, such as hydrogels, can be mechanically secured to electrodes of an implantable device, such as electrodes made of noble metals. The hydrogel can be mechanically secured via anchoring features of the electrode. Anchoring features can include apertures, voids, textures, or other patterns created in or on the electrode. The hydrogel can incorporate into the anchoring features to mechanically hold the hydrogel against the electrode. The anchoring features, by being located in or on the electrode, can further increase the surface area of the electrode that is exposed to the hydrogel, which can facilitate the conduction of electrical signals between the electrode and surrounding biological tissue. The substrate supporting the electrode can include additional anchoring features that further assist in mechanically securing the hydrogel.
    • 可以将生物材料如水凝胶机械固定到可植入装置的电极,例如由贵金属制成的电极。 水凝胶可以通过电极的锚固特征机械地固定。 锚定特征可以包括在电极中或其上形成的孔,空隙,纹理或其他图案。 水凝胶可以并入锚定特征中以机械地将水凝胶保持在电极上。 锚定特征通过位于电极中或电极上可以进一步增加暴露于水凝胶的电极的表面积,这可以促进电极与周围生物组织之间的电信号的传导。 支撑电极的基底可以包括另外的锚定特征,其进一步有助于机械固定水凝胶。
    • 6. 发明申请
    • SYSTEM AND METHOD FOR IDENTIFICATION OF BRAIN INJURY
    • 用于识别脑损伤的系统和方法
    • WO2018026974A1
    • 2018-02-08
    • PCT/US2017/045189
    • 2017-08-02
    • MOTOMETRIX INC.
    • BADEER, Preston
    • A61B5/00A61H1/00A61H1/02A61N1/00A61N1/36A63B26/00A63B71/00
    • A61B5/4064A61B5/0002A61B5/1036A61B5/4023A61B5/7278A61B5/7282A61B2090/064A61B2560/0475A61B2562/046
    • A method for identifying brain injuries in a test subject includes acquiring, at a selected number of instances across a selected time interval, a set of signals indicative of force from a set of force sensors when the test subject stands on a pressure measurement unit. The method includes calculating a center-of-pressure of the test subject at the selected number of instances across the selected time interval based on the acquired set of signals from the set of force sensors. The method includes calculating a metric indicative of randomness of the center-of- pressure of the test subject across the selected time interval. The method includes determining a state of brain health of the test subject based on the metric indicative of randomness of the center-of-pressure. The method includes reporting the state of brain health of the test subject to a user interface.
    • 用于识别测试对象中的脑损伤的方法包括:在选定的时间间隔内的选定数量的实例处获取指示来自一组力传感器的力的信号,当测试对象 站在压力测量单元上。 该方法包括基于从所述一组力传感器获取的一组信号来计算在所选择的时间间隔内的选定数量的实例处的测试对象的压力的中心。 该方法包括计算指示在所选时间间隔内测试对象的压力中心的随机性的度量。 该方法包括基于指示压力中心的随机性的度量来确定测试对象的大脑健康状态。 该方法包括向用户界面报告测试对象的大脑健康状态。