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    • 27. 发明授权
    • Method and device for decoding in a differential orthogonal space-time block coded system
    • 用于在差分正交空时块编码系统中解码的方法和装置
    • US08923458B2
    • 2014-12-30
    • US13766910
    • 2013-02-14
    • Industry-Academic Cooperation Foundation, Yonsei University
    • Jong-Soo SeoJae Shin HanJong Seob Baek
    • H04L1/02H04L1/06H04B7/08
    • H04B7/0891H04L1/0631H04L1/0668
    • A method and device for decoding in a differential orthogonal space-time block coded system are disclosed. The disclosed method includes: (a) receiving signals from a transmitter during a particular time slot segment, where the signals are encoded by differential orthogonal space-time block coding; (b) transforming to reception signals for two sub-systems by using a sum operation and a difference operation of the signals received in step (a), where the transformed reception signals for the two sub-systems maintain an orthogonality of an orthogonal space-time block coded system; and (c) performing decoding using the reception signals for the two sub-systems transformed in step (b). The method provides the advantage of lowering the level of operational complexity for decoding in a communication system that employs differential orthogonal space-time block coding.
    • 公开了一种在差分正交空时块编码系统中解码的方法和装置。 所公开的方法包括:(a)在特定时隙段期间从发射机接收信号,其中信号由差分正交空时块编码编码; (b)通过使用在步骤(a)中接收的信号的和操作和差分运算来转换为两个子系统的接收信号,其中用于两个子系统的经变换的接收信号保持正交空间 - 时间块编码系统; 和(c)使用在步骤(b)中变换的两个子系统的接收信号来执行解码。 该方法提供了在采用差分正交空时块编码的通信系统中降低解码操作复杂度的优点。
    • 29. 发明授权
    • Safer attenuated varicella-zoster virus vaccines with missing or diminished latency of infection
    • 更安全的减毒水痘带状疱疹病毒疫苗缺失或减少的潜伏期的感染
    • US08916175B2
    • 2014-12-23
    • US11630147
    • 2005-06-22
    • Jeffrey I. CohenEdward M. Cox, Jr.Lesley M. Pesnicak
    • Jeffrey I. CohenEdward M. Cox, Jr.Lesley M. Pesnicak
    • A61K39/25A01N63/00C12N7/00C12N7/04
    • A61K39/25A61K39/12C12N7/00C12N2710/16734C12N2710/16761C12N2710/16762
    • Viruses having weakened ability to establish and/or maintain latency and their use as live vaccines are described. The vaccines have one or more alterations in genes that provide continued virus replication but that inhibit latency. The vaccine materials and methods for their construction are exemplified with the varicella zoster virus. Deletion of a significant portion from both copies of the varicella zoster gene ORF63 was shown to inhibit establishment of a latent infection from a live vaccine form of the virus. Insertion of an additional ORF62 gene which is partially truncated with the ORF63 deletion inhibited establishment of latency and allowed normal growth of the virus. Other desirable viral antigen encoding sequence(s) and/or cytokine genes advantageously may replace deleted genetic material to enhance a desired immunological response. Aspects of the discovery pertain to live vaccines of other viruses, and can provide a variety of vaccines having greater safety.
    • 描述了具有削弱建立和/或维持延迟的能力及其作为活疫苗的用途的病毒。 疫苗在提供持续病毒复制但抑制潜伏期的基因中具有一个或多个改变。 用于其构建的疫苗材料和方法以水痘带状疱疹病毒为例。 从水痘带状疱疹基因ORF63的两个拷贝中删除重要部分被证明可以抑制病毒活疫苗形式的潜伏感染的建立。 用ORF63缺失部分截断的另外的ORF62基因的插入抑制了潜伏期的建立并允许病毒的正常生长。 其他所需的病毒抗原编码序列和/或细胞因子基因有利地可以代替缺失的遗传物质以增强所需的免疫应答。 该发现的方面涉及其他病毒的活疫苗,并且可以提供具有更高安全性的多种疫苗。