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31. 发明授权

US06280433B1 Introducer system 有权
标题翻译：介绍系统
公开(公告)号：US06280433B1
公开(公告)日：2001-08-28
申请号：US09392715
申请日：1999-09-09
申请人： Michael E. McIvor , Kenneth C. Gardeski , Pedro A. Meregotte , Mathew D. Bonner , Timothy G. Laske , Linda L. Lach
发明人： Michael E. McIvor , Kenneth C. Gardeski , Pedro A. Meregotte , Mathew D. Bonner , Timothy G. Laske , Linda L. Lach
IPC分类号： A61M2500
CPC分类号： A61M25/0668 , A61M25/01 , A61M2025/0675
摘要： An introducer or guide catheter for directing an implantable medical device such as a lead or catheter to a desired location within a patient's body. In one embodiment of the invention, the introducer comprises a two-lumen tube. A first lumen is configured to receive the implantable medical device that is to be introduced. A second lumen is provided to receive an insertable, elongated guiding member such as a stylet, which may be shapable in various orientations, and which may be used to alter the configuration of the introducer. The second lumen may be provided with an internal coil or other tubular reinforcement member to prevent perforation of this lumen by the guiding member when the introducer is in the patient's body. In order to facilitate removal of the introducer over an implantable medical device having a connector or fitting that is larger than the internal diameter of the first lumen, the introducer may be adapted to be slit or split along its length. In some embodiments of the invention, the introducer may be rendered splittable by provision of a weakened zone along its length. According to yet another aspect of the invention, the introducer may be provided with a luer lock at its proximal end to facilitate connection of the introducer to a hemostasis valve, t-fitting, or the like.
摘要翻译：导引器或引导导管，用于将诸如引线或导管的可植入医疗装置引导到患者体内的期望位置。在本发明的一个实施例中，导引器包括两腔管。第一管腔被配置为接收待引入的可植入医疗装置。提供第二内腔以接收可插入的细长引导构件，例如探针，其可以以各种取向成形，并且其可以用于改变导引器的构造。第二内腔可以设置有内部线圈或其他管状加强构件，以在导引器位于患者体内时防止引导构件对该内腔穿孔。为了便于在具有大于第一内腔的内径的连接器或配件的可植入医疗装置上移除导引器，导引器可以适于沿着其长度被切割或分开。在本发明的一些实施例中，导引器可以通过沿着其长度提供弱化区域而被分解。根据本发明的另一方面，导引器在其近端可以设置有鲁尔锁，以便于将导引器连接到止血阀，t形配件等。

32. 发明授权

US08509899B2 Multi-electrode implantable systems and assemblies thereof 有权
标题翻译：多电极可植入系统及其组件
公开(公告)号：US08509899B2
公开(公告)日：2013-08-13
申请号：US13008524
申请日：2011-01-18
申请人： John Louis Sommer , Joseph Michael D'Sa , Joyce K. Yamamoto , Brad C. Tischendorf , James D. Reinke , Andrew J. Thom , Thomas P. Miltich , William John Taylor , Kenneth C. Gardeski , Larry Earl Tyler , Jeffrey O. York , Gordon O. Munns
发明人： John Louis Sommer , Joseph Michael D'Sa , Joyce K. Yamamoto , Brad C. Tischendorf , James D. Reinke , Andrew J. Thom , Thomas P. Miltich , William John Taylor , Kenneth C. Gardeski , Larry Earl Tyler , Jeffrey O. York , Gordon O. Munns
IPC分类号： A61N1/362
CPC分类号： A61N1/362 , A61N1/05 , A61N1/056 , A61N1/372
摘要： Hermetically sealed assemblies, for example, that include IC chips, are configured for incorporation within a connector terminal of an implantable medical electrical lead, preferably within a contact member of the terminal. An assembly may include two feedthrough subassemblies, welded to either end of the contact member, to form an hermetic capsule, in which an IC chip is enclosed, and a tubular member, which allows a lumen to extend therethrough, along a length of the terminal. A multi-electrode lead may include multiplexer circuitry, preferably a switch matrix element and a communications, control and power supply element that are electrically coupled to the contact member and to another contact member of the terminal. Each pair of switch matrix switches allows for any two of the electrodes to be selected, in order to deliver a stimulation vector, via stimulation pulses from a device/pulse generator, to which the connector terminal is connected.
摘要翻译：例如，包括IC芯片的密封组件被配置为并入可植入医疗电线的连接器端子内，优选地在端子的接触构件内。组件可以包括焊接到接触构件的任一端的两个馈通子组件，以形成封闭IC芯片的密封胶囊，以及允许内腔沿着端子的长度延伸穿过的管状构件。多电极引线可以包括多路复用器电路，优选地是开关矩阵元件和通信，控制和电源元件，其电耦合到接触构件和终端的另一接触构件。每对开关矩阵开关允许选择任何两个电极，以便通过来自连接器端子连接到的装置/脉冲发生器的刺激脉冲传送刺激矢量。

33. 发明申请

US20110270170A1 Steerable Medical Device Having Means For Imparting Multiple Curves in the Device 审中-公开
标题翻译：具有装置中多个曲线的手段的可导向医疗装置
公开(公告)号：US20110270170A1
公开(公告)日：2011-11-03
申请号：US12771333
申请日：2010-04-30
申请人： Kenneth C. Gardeski , Ronald Alan Drake
发明人： Kenneth C. Gardeski , Ronald Alan Drake
IPC分类号： A61M25/092 , A61M25/00
CPC分类号： A61M25/0136 , A61M25/0133
摘要： A steerable elongated medical device that is capable of forming as “s” shaped bend. The devices include an outer tube extending between an outer tube proximal segment and an outer tube distal segment, having an outer tube wall forming an outer tube lumen and first and second elongated outer tube slots through the outer tube wall to the outer tube lumen. The first elongated outer tube slot has a first portion and a second portion and formed between a first outer tube slot proximal end and a first outer tube slot distal end and extending axially along the outer tube distal segment through a first outer tube slot length to define a first cutaway portion of the outer tube. The second elongated outer tube slot has a first portion and a second portion and formed between a second outer tube slot proximal end and a second outer tube slot distal end and extending axially along the outer tube distal segment through a second outer tube slot length to define a second cutaway portion of the outer tube and offset about 180 degrees from the first elongated outer tube slot. Each of the first and second outer tube slots have reinforcing sleeves, each of the reinforcing sleeves having reinforcing sleeve slot portions and reinforcing sleeve overlap portions.
摘要翻译：一种能够形成“s”形弯曲的可操纵的细长医疗装置。这些装置包括在外管近端段和外管远端段之间延伸的外管，其具有形成外管腔的外管壁和穿过外管壁到外管内腔的第一和第二细长外管狭槽。第一细长外管狭槽具有第一部分和第二部分，并且形成在第一外管狭缝近端和第一外管狭槽远端之间，并且通过第一外管狭槽长度沿着外管远端段轴向延伸以限定外管的第一切除部分。第二细长外管狭槽具有第一部分和第二部分，并且形成在第二外管狭缝近端和第二外管狭槽远端之间，并且通过第二外管狭槽长度沿着外管远端段轴向延伸以限定外管的第二切口部分并且与第一细长外管狭槽偏移大约180度。第一和第二外管槽中的每一个具有加强套管，每个加强套管具有加强套管槽部分和加强套管重叠部分。

34. 发明申请

US20100280363A1 Electromagnetic Navigation of Medical Instruments for Cardiothoracic Surgery 审中-公开
标题翻译：医学仪器用于心胸外科的电磁导航
公开(公告)号：US20100280363A1
公开(公告)日：2010-11-04
申请号：US12767163
申请日：2010-04-26
申请人： James Skarda , Mark Stewart , James Keogh , David Francischelli , Kenneth C. Gardeski , Thomas A. Poss , Michael Neidert
发明人： James Skarda , Mark Stewart , James Keogh , David Francischelli , Kenneth C. Gardeski , Thomas A. Poss , Michael Neidert
IPC分类号： A61B5/05
CPC分类号： A61B1/00154 , A61B1/00135 , A61B34/20 , A61B90/361 , A61B2017/00243 , A61B2017/00336 , A61B2034/2051 , A61N1/056
摘要： The present invention provides devices, instruments, systems, and methods to navigate medical instruments within the thoracic cavity. More specifically, the present invention provides a navigation system comprising medical instruments having electromagnetic tracking functionality and the integration of previously acquired imaging into a user interface of the navigation system.
摘要翻译：本发明提供了用于在胸腔内导航医疗器械的装置，仪器，系统和方法。更具体地，本发明提供了一种导航系统，其包括具有电磁跟踪功能的医疗仪器和将先前获取的成像集成到导航系统的用户界面中。

35. 发明申请

US20090275956A1 TECHNIQUES FOR PLACING MEDICAL LEADS FOR ELECTRICAL STIMULATION OF NERVE TISSUE 有权
公开(公告)号：US20090275956A1
公开(公告)日：2009-11-05
申请号：US12433766
申请日：2009-04-30
申请人： John E. Burnes , Kenneth C. Gardeski , Ruth N. Klepfer , Patrick E. Macaulay , Mary M. Morris , Avram Scheiner
发明人： John E. Burnes , Kenneth C. Gardeski , Ruth N. Klepfer , Patrick E. Macaulay , Mary M. Morris , Avram Scheiner
IPC分类号： A61B17/00
CPC分类号： A61N1/36053 , A61M25/09 , A61N1/05 , A61N1/0551 , A61N1/0558 , A61N1/057 , A61N1/36085 , A61N1/36114 , A61N1/36125 , A61N1/36128
摘要： This disclosure is directed to extra, intra, and transvascular medical lead placement techniques for arranging medical leads and electrical stimulation and/or sensing electrodes proximate nerve tissue within a patient.

36. 发明申请

US20080132800A1 NOVEL MEDICAL METHODS AND SYSTEMS INCORPORATING WIRELESS MONITORING 有权
标题翻译：新型医疗方法与系统无线监控
公开(公告)号：US20080132800A1
公开(公告)日：2008-06-05
申请号：US11565283
申请日：2006-11-30
申请人： Douglas A. Hettrick , Kenneth C. Gardeski , H. Toby Markowitz , Sameh Sowelam
发明人： Douglas A. Hettrick , Kenneth C. Gardeski , H. Toby Markowitz , Sameh Sowelam
IPC分类号： A61B5/04 , A61B5/00
CPC分类号： A61B5/076 , A61B5/0031 , A61B5/1107 , A61B5/686 , A61B90/39 , A61B2017/00411 , A61B2090/3908 , A61B2090/397 , A61B2090/3975 , A61B2562/0209 , A61B2562/046
摘要： Medical systems and methods incorporate monitoring of at least two implanted markers, each of which is adapted to wirelessly transmit a signal in response to a wirelessly transmitted excitation signal; the response signals are converted into positional information for the two markers. The systems and methods further incorporate both, or one of, an implanted sensing member and/or an implanted therapy delivery device. Signals received from the sensing member may be collated with the positional information. A therapy delivered from the therapy delivery device may be adjusted according to the positional information.
摘要翻译：医疗系统和方法包括至少两个植入标记的监测，每个植入标记适于响应于无线发送的激励信号无线地发送信号; 响应信号被转换成两个标记的位置信息。所述系统和方法还包括植入的感测构件和/或植入的治疗递送装置中的一个或其中之一。从感测构件接收到的信号可以与位置信息进行整理。可以根据位置信息调整从治疗输送装置输送的治疗。

37. 发明授权

US07338481B2 Slitting tool 有权
标题翻译：分切工具
公开(公告)号：US07338481B2
公开(公告)日：2008-03-04
申请号：US10367420
申请日：2003-02-14
申请人： Kenneth C. Gardeski , Jeff J. Jannicke , Stanten C. Spear , David A. Schuelke , Debbie L. Kirihara , Elizabeth A. Ellingson , Jeremy J. Odegard , Richard P. Manahan , Andrzej M. Malewicz
发明人： Kenneth C. Gardeski , Jeff J. Jannicke , Stanten C. Spear , David A. Schuelke , Debbie L. Kirihara , Elizabeth A. Ellingson , Jeremy J. Odegard , Richard P. Manahan , Andrzej M. Malewicz
IPC分类号： A61M25/00 , A61M31/00
CPC分类号： B26D3/001 , A61M25/00 , A61M25/0668 , A61M2025/0675
摘要： A slitting tool for severing a tubular body includes a body portion, extending along a first axis, joined to a nose portion extending along a second axis, the second axis extending at an angle between approximately 5 degrees and approximately 90 degrees with respect to the first axis. The nose portion includes means for severing the tubular body while the body portion includes means for gripping by a hand of a user such that a wrist of the hand is in a neutral position when the means for severing is directed toward the tubular body.
摘要翻译：用于切割管状体的切割工具包括主体部分，其沿着第一轴线延伸，与第二轴线延伸的鼻部接合，第二轴线相对于第一轴线以大约5度和大约90度之间的角度延伸轴。鼻部包括用于切断管状体的装置，而主体部分包括用于由使用者的手握住的装置，使得当切割装置指向管状体时，手的手腕处于中立位置。

38. 发明授权

US07130700B2 Multilumen body for an implantable medical device 有权
标题翻译：用于可植入医疗器械的多组织体
公开(公告)号：US07130700B2
公开(公告)日：2006-10-31
申请号：US10299484
申请日：2002-11-19
申请人： Kenneth C. Gardeski , Michael R. Leners
发明人： Kenneth C. Gardeski , Michael R. Leners
IPC分类号： A61N1/375 , A61B19/00
CPC分类号： A61M25/0023 , A61M25/0021 , A61M25/0032 , A61M2025/0036
摘要： A splined multilumen body for use in elongated medical devices is provided for carrying multiple conductors, wires or cables to multiple device components along the device body. Open lumens may be provided through which medical devices or therapies may be delivered. The multilumen body is constructed from a generally tubular outer member having inward-radiating splines that mate with outward-radiating splines on a generally tubular inner member. Lumens formed between sets of mated splines isolate conductors carried therein. Interaction of mated splines provides good torque transfer between outer and inner members. Materials for fabricating outer and inner members may be selected to achieve desired torque transfer properties, flexibility, and surface friction.
摘要翻译：提供用于细长医疗装置的花键多体体，用于沿着装置主体将多个导体，电线或电缆携带到多个装置部件。可以提供开放的流明，通过该腔可以递送医疗装置或治疗物。多腔体由大致管状的外部构件构成，该外部构件具有与大致管状的内部构件上的向外辐射花键相配合的向内辐射花键。在组合的配对花键之间形成的流明隔离导体中的导体。配对花键的相互作用提供了外部和内部构件之间良好的扭矩传递。可以选择用于制造外部和内部构件的材料以实现期望的扭矩传递特性，柔性和表面摩擦。

39. 发明授权

US06934589B2 System and method for placing endocardial leads 失效
标题翻译：放置心内膜导管的系统和方法
公开(公告)号：US06934589B2
公开(公告)日：2005-08-23
申请号：US09827108
申请日：2001-04-05
申请人： Stephen Sundquist , Arnold Thornton , Roger Dahl , Duane Zytkovicz , Kenneth C. Gardeski
发明人： Stephen Sundquist , Arnold Thornton , Roger Dahl , Duane Zytkovicz , Kenneth C. Gardeski
IPC分类号： A61N1/05 , A61N1/00
CPC分类号： A61N1/056 , A61N2001/0578 , A61N2001/0585
摘要： An improved system and method for deploying medical electrical leads is disclosed. The system includes a guiding device such as a guidewire used to navigate the vascular system of a body. The guiding device includes a fixation member that can be deployed to maintain the guiding device at a desired location within the vascular system. The fixation member may be an inflatable device such as a balloon, or alternatively, may be an expandable device constructed of flexible fibers that has both an expanded and a contracted state. The system may further include a coupling member located adjacent to the guiding device. The coupling member may be a rail extending distally from a proximal end of the guiding device to a point proximal the fixation member. In an alternative embodiment of the invention, the coupling member is a channel included in the body of the guiding device adapted to slidably engage an electrode assembly. The coupling member is adapted to allow the electrode assembly to be slid to the distal end of the coupling member and deployed at a predetermined implant site. In one embodiment of the invention, the coupling member is movable with respect to the guiding device. This allows the coupling member to be re-positioned to multiple implant sites to deploy more than one electrode while the fixation mechanism remains stationary within a patient's vascular system. According to yet another aspect of the invention, the guiding device includes a lumen to delivery fluoro visible medium.
摘要翻译：公开了用于部署医疗电引线的改进的系统和方法。该系统包括诸如用于导航身体的血管系统的导丝的引导装置。引导装置包括可以部署以将引导装置保持在血管系统内的期望位置的固定构件。固定构件可以是诸如气囊的可充气装置，或者可替代地，可以是由具有膨胀和收缩状态的柔性纤维构成的可扩张装置。该系统还可以包括邻近引导装置定位的联接构件。联接构件可以是从引导装置的近端向靠近固定构件的点向远侧延伸的轨道。在本发明的替代实施例中，联接构件是包括在引导装置的主体中的通道，其适于可滑动地接合电极组件。联接构件适于允许电极组件滑动到联接构件的远端并且在预定的植入位置展开。在本发明的一个实施例中，联接构件可相对于引导装置移动。这允许将联接构件重新定位到多个植入位置以展开多于一个电极，同时固定机构在患者的血管系统内保持静止。根据本发明的另一方面，引导装置包括用于输送氟可见介质的内腔。

40. 发明授权

US06836687B2 Method and system for delivery of a medical electrical lead within a venous system 有权
标题翻译：用于在静脉系统内递送医用电线的方法和系统
公开(公告)号：US06836687B2
公开(公告)日：2004-12-28
申请号：US10131388
申请日：2002-04-25
申请人： James F. Kelley , James H. Vaughn , Stanten C. Spear , Douglas S. Hine , Kenneth C. Gardeski , Vicki L. Bjorklund , Pedro A. Meregotte , John L. Sommer , John J. Maier
发明人： James F. Kelley , James H. Vaughn , Stanten C. Spear , Douglas S. Hine , Kenneth C. Gardeski , Vicki L. Bjorklund , Pedro A. Meregotte , John L. Sommer , John J. Maier
IPC分类号： A61N105
CPC分类号： A61M25/0138 , A61B18/1492 , A61B2017/22038 , A61M25/005 , A61M25/0054 , A61M25/0141 , A61M25/0147 , A61M25/0668 , A61M39/0613 , A61M2025/0042 , A61M2025/0047 , A61M2025/0081 , A61M2025/0161 , A61M2025/0681 , A61M2025/1052 , A61M2025/1079 , A61N1/05 , A61N1/056 , A61N2001/0578 , A61N2001/0585
摘要： A system for delivering a medical electrical lead within a coronary venous system that includes an introducer kit for establishing venous access to the coronary venous system and a plurality of delivery sheaths, each corresponding to a desired approach to a coronary sinus of the coronary venous system and insertable within the coronary venous system through the navigation pathway. A hemostasis valve is coupled to a delivery sheath of the plurality of delivery sheaths, and a guide wire is inserted within the lead lumen, guiding delivery of the distal tip of the medical electrical lead to a target site within the coronary venous system through the hemostasis valve and the delivery sheath. Subsequent to the distal tip being delivered to the target sight, the hemostasis valve is advanced over the connector of the medical electrical lead to remove the hemostasis valve from the medical electrical lead.
摘要翻译：一种用于在冠状静脉系统内递送医用电线的系统，其包括用于建立对冠状静脉系统的静脉通路的引导器套件和多个输送护套，每个输送护套对应于冠状静脉系统的冠状窦所需的方法，通过导航路径插入冠状静脉系统内。止血阀联接到多个输送护套的输送护套，并且引导线插入引导腔内，通过止血将医用电导线的远端引导到冠状静脉系统内的靶位点阀门和输送护套。在远端尖端被传送到目标瞄准器之后，止血阀在医用电线的连接器上前进，以从医用电引线上除去止血阀。

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