专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

81. 发明授权

US4547524A Insecticidal benzoyl hydrazone derivatives 失效
标题翻译：杀虫剂苯甲酰腙衍生物
公开(公告)号：US4547524A
公开(公告)日：1985-10-15
申请号：US466101
申请日：1983-02-14
申请人： Kimiyoshi Kaneko , Hiromichi Ishikawa , Satoru Moriyama , Tsugio Uchiyama
发明人： Kimiyoshi Kaneko , Hiromichi Ishikawa , Satoru Moriyama , Tsugio Uchiyama
IPC分类号： A01N37/28 , A01N37/40 , A01N47/24 , A01N47/34 , C07C67/00 , C07C239/00 , C07C241/00 , C07C251/72 , C07C251/76 , C07C251/84 , C07C251/86 , C07C109/10 , A01N37/18 , A01N47/28 , C07C127/22
CPC分类号： C07C251/72 , A01N37/28 , A01N37/40 , A01N47/24 , A01N47/34
摘要： Compounds of the formula ##STR1## wherein R.sub.1, R.sub.2, R.sub.3 and R.sub.4 are as herein defined useful as insecticides, is described.
摘要翻译：描述了其中R 1，R 2，R 3和R 4如本文所定义的用作杀虫剂的式“IMAGE”的化合物。

82. 发明授权

US4528367A Method and intermediates for preparing high purity 3,3'-azo-bis-(6-hydroxy benzoic acid) 失效
标题翻译：制备高纯度3,3'-偶氮双（6-羟基苯甲酸）的方法和中间体
公开(公告)号：US4528367A
公开(公告)日：1985-07-09
申请号：US462356
申请日：1983-01-31
申请人： Karl H. Agback , Alf S. Nygren
发明人： Karl H. Agback , Alf S. Nygren
IPC分类号： A61K31/19 , A61K31/655 , A61P1/00 , A61P1/04 , C07C67/00 , C07C241/00 , C07C245/08 , C07C301/00 , C07C303/30 , C07C309/04 , C07C309/29 , C07C309/66 , C07C309/73 , C09B29/14 , C09B43/24 , C07C107/06 , C09B29/01 , C09B43/00
CPC分类号： C07C245/08 , C09B29/14 , C09B43/24
摘要： A method of preparing 3,3'-azo-bis-(6-hydroxy benzoic acid) of formula I ##STR1## and salts thereof in at least 98% purity for treating inflammatory intestinal diseases. According to the invention a compound II ##STR2## is diazotized, and the diazonium salt obtained is coupled with a compound III ##STR3## The formed intermediate IV, which is also comprised by the invention, ##STR4## is hydrolized in alkaline medium to form the compound I. R.sub.1, R.sub.2 and R.sub.3 signify lower alkyl, R.sub.2 also possibly substituted phenyl.
摘要翻译：制备式I的3,3'-偶氮双（6-羟基苯甲酸）的方法及其盐，其至少98％的纯度用于治疗炎症性肠病。根据本发明，化合物II II被重氮化，所得的重氮盐与化合物III III连接。本发明也包含的形成的中间体IV在碱性条件下水解培养基形成化合物I.R 1，R 2和R 3表示低级烷基，R 2也可能被取代的苯基。

83. 发明授权

US4515628A Diphenyl ether derivatives and herbicides containing same 失效
标题翻译：二苯醚衍生物和含有相同的除草剂
公开(公告)号：US4515628A
公开(公告)日：1985-05-07
申请号：US287654
申请日：1981-07-28
申请人： Takeo Yoshimoto , Akira Hosono , Joh Miki , Kengo Oda , Masaaki Ura , Naoki Sato , Teruhiko Toyama , Hajime Tachibana , Yuji Enomoto , Yasunobu Funakoshi , Takashi Fujita , Yoshikata Hojo
发明人： Takeo Yoshimoto , Akira Hosono , Joh Miki , Kengo Oda , Masaaki Ura , Naoki Sato , Teruhiko Toyama , Hajime Tachibana , Yuji Enomoto , Yasunobu Funakoshi , Takashi Fujita , Yoshikata Hojo
IPC分类号： A01N25/02 , A01N25/12 , A01N25/30 , A01N31/14 , A01N33/22 , A01N33/26 , A01N35/10 , A01N37/28 , A01N37/30 , A01N37/32 , A01N37/36 , A01N37/42 , A01N37/44 , A01N37/50 , A01N37/52 , A01N39/02 , A01N39/04 , A01N41/02 , A01N43/08 , A01N43/36 , A01N43/46 , A01N47/24 , A01N47/34 , A01N47/38 , A01N47/42 , A01N51/00 , A01N57/00 , A01N57/22 , A01P13/00 , C07C43/168 , C07C67/00 , C07C239/00 , C07C241/00 , C07C243/22 , C07C243/28 , C07C243/38 , C07C251/02 , C07C253/00 , C07C255/61 , C07C281/00 , C07C281/02 , C07C281/06 , C07C311/49 , C07C323/48 , C07C325/00 , C07C337/02 , C07C337/06 , C07D207/40 , C07D207/404 , C07D207/452 , C07D207/456 , C07D207/50 , C07D209/44 , C07D209/46 , C07D209/48 , C07D223/10 , C07D227/08 , C07D307/48 , C07D307/52 , C07F9/24 , A01N37/48 , C07C79/46
CPC分类号： C07D207/404 , A01N33/26 , A01N35/10 , A01N37/28 , A01N37/30 , A01N37/32 , A01N37/44 , A01N37/50 , A01N37/52 , A01N39/04 , A01N43/08 , A01N47/24 , A01N47/34 , A01N47/42 , C07C243/00 , C07C243/38 , C07C251/72 , C07C323/48 , C07D207/50 , C07D209/48 , C07D223/10 , C07D307/52 , C07F9/2491
摘要： Novel diphenyl ether hydrazine derivatives, particularly 2-nitro-5 (nucleus-substituted phenoxy) phenylhydrazine derivatives are provided. They are useful as a selective herbicide having a high herbicidal acitivity and residual efficacy.
摘要翻译：提供新的二苯醚肼衍生物，特别是2-硝基-5（核 - 取代苯氧基）苯肼衍生物。它们可用作具有高除草活性和残留功效的选择性除草剂。

84. 发明授权

US4499023A Process for separating technically pure 2,4-diisocyanatotoluene or isomer mixtures having an increased content of 2,4-diisocyanatotoluene from isomer mixtures of 2,4- and 2,6-diisocyanatotoluene 失效
标题翻译：从2,4-和2,6-二异氰酸基甲苯的异构体混合物中分离技术上纯的2,4-二异氰酸基甲苯或异构体混合物的方法，其具有增加的2,4-二异氰酸根合甲苯含量
公开(公告)号：US4499023A
公开(公告)日：1985-02-12
申请号：US493869
申请日：1983-05-12
申请人： Alexander Mitrowsky , Adolf Wissner , Werner Hauser
发明人： Alexander Mitrowsky , Adolf Wissner , Werner Hauser
IPC分类号： C07C265/14 , C07C67/00 , C07C71/00 , C07C241/00 , C07C249/14 , C07C263/18 , C07C265/12
CPC分类号： C07C263/20
摘要： Technically pure 2,4-diisocyanatotoluene or an isomer mixture having an increased 2,4-diisocyanatotoluene content is obtained from an isomer mixture of 2,4- and 2,6-diisocyanatotoluene. The 2,4- and 2,6-diisocyanatotoluene mixture is first cooled to a temperature of from 4.degree. to 9.degree. C. and further cooled to between -2.degree. to -6.degree. C. at a rate of 0.5.degree. to 3.degree. C. per hour. The temperature of the mixture is maintained at that temperature for at least 30 minutes. Any liquid present is removed and the solid remaining is then melted. Melting is preferably carried out by heating the solid at a rate of 0.5.degree. to 3.degree. C. per hour until the remaining solid has a 2,4-diisocyanatotoluene content of at least 98%. The liquid melt is removed and the solid having the desired 2,4-diisocyanatotoluene content is then melted.
摘要翻译：从2,4-和2,6-二异氰酸基甲苯的异构体混合物获得技术上纯的2,4-二异氰酸基甲苯或具有增加的2,4-二异氰酸基甲苯含量的异构体混合物。首先将2,4-和2,6-二异氰酸基甲苯混合物冷却至4℃至9℃的温度，并以0.5至3℃的速度进一步冷却至-2至-6℃。每小时C. 将混合物的温度保持在该温度下至少30分钟。取出任何存在的液体，然后将剩下的固体熔化。熔融优选通过以0.5至3℃/小时的速率加热固体直到剩余的固体具有至少98％的2,4-二异氰酸基甲苯含量来进行。然后除去液体熔体，然后将具有所需2,4-二异氰酸基甲苯含量的固体熔化。

85. 发明授权

US4492657A Imines of alkyl 4-halomethylbenzoates 失效
标题翻译：亚胺的4-卤代甲基苯甲酸烷基酯
公开(公告)号：US4492657A
公开(公告)日：1985-01-08
申请号：US488126
申请日：1983-04-25
申请人： Lorenz Heiss
发明人： Lorenz Heiss
IPC分类号： C07C257/08 , C07C67/00 , C07C241/00 , C07C119/20
CPC分类号： C07C257/08
摘要： New alkyl (4-halomethyl)iminobenzoates of the formula ##STR1## and their HCl or HBr salts, R denoting C.sub.1 -C.sub.4 -alkyl or C.sub.1 -C.sub.4 -alkoxyethyl and X denoting Cl or Br. These compounds are prepared by reaction of p-cyanobenzyl chloride or p-cyanobenzyl bromide with a C.sub.1 -C.sub.4 -alcohol or C.sub.1 -C.sub.4 -alkoxyethanol in the presence of hydrogen chloride or bromide. The new imines serve as intermediate products, inter alia for the preparation of optical brighteners of the bisbenzoxazolylstilbene class.
摘要翻译：式（IMAGE）的新的烷基（4-卤甲基）亚氨基苯甲酸酯及其HCl或HBr盐，R表示C 1 -C 4烷基或C 1 -C 4 - 烷氧基乙基，X表示Cl或Br。这些化合物是通过在氯化氢或溴化氢存在下使对氰基苄基氯或对氰基苄基溴与C 1 -C 4醇或C 1 -C 4 - 烷氧基乙醇反应来制备的。新的亚胺作为中间体产品，尤其用于制备双苯并恶唑基茋类荧光增白剂。

86. 发明授权

US4486603A Preparation of trans cyclohexane 1,4-diamine 失效
标题翻译：反式环己烷1,4-二胺的制备
公开(公告)号：US4486603A
公开(公告)日：1984-12-04
申请号：US420186
申请日：1982-09-20
申请人： Hans Zengel , Manfred Bergfeld
发明人： Hans Zengel , Manfred Bergfeld
IPC分类号： C07C271/24 , C07C67/00 , C07C209/00 , C07C209/56 , C07C211/36 , C07C231/00 , C07C231/02 , C07C235/58 , C07C239/00 , C07C241/00 , C07C263/06 , C07C265/00 , C07C265/14 , C07C273/18 , C07C275/04 , C07C275/26 , C07C311/56 , C07D295/20 , C07C85/00 , C07C87/36
CPC分类号： C07C273/1845 , C07C311/56
摘要： A process is disclosed for selectively making trans-cyclohexane-1,4-diisocyanate, trans-cyclohexane-1,4-diamine, a trans-cyclohexane-1,4-diurethane, a trans-cyclohexane-1,4-diurea and trans-cyclohexane-1,4-disulphonyl urea by reacting ammonia with a mixture of cis and trans cyclohexane-1,4-dicarboxylic acid, a lower alkyl ester, a glycol ester, an oligomeric ester or a polyester to make a solid trans-dicarboxylic acid diamide in a first step. The diamide is chlorinated to form trans-cyclohexane-1,4-dicarboxylic acid-bis-N-chloramide. The latter compound is then converted into a(a) trans-cyclohexane-1,4-diamine with an alkali metal hydroxide or alkaline earth metal hydroxide; or into a(b) a trans-cyclohexane-1,4-diurethane by reaction with an alcohol or glycol in a reaction mixture containing an alkali metal hydroxide or alkaline earth metal hydroxide; or into(c) a trans-cyclohexane-1,4-diurea by reaction with a primary or secondary amine in a reaction mixture containing an alkali metal hydroxide or alkaline earth metal hydroxide; or into a(d) trans-cyclohexane-1,4-sulphonyl urea by reaction with a primary sulphonamide in a reaction mixture containing an alkali metal hydroxide and dimethyl formamide and water.The diurea prepared in (c) may be converted into trans-cyclohexane-1,4-diisocyanate with gaseous hydrogen chloride in an inert solvent. The diurethane prepared in (b) and the disulphonyl urea prepared in (d) may be thermally decomposed into trans-cyclohexane-1,4-diisocyanate.
摘要翻译：公开了一种选择性制备反式环己烷-1,4-二异氰酸酯，反式环己烷-1,4-二胺，反式环己烷-1,4-二氨基甲酸酯，反式环己烷-1,4-二脲和反式环己烷-1,4-二脲 - 环己烷-1,4-二磺酰脲通过使氨与顺式和反式环己烷-1,4-二羧酸，低级烷基酯，乙二醇酯，低聚酯或聚酯的混合物反应制得固体反式二羧酸酸二酰胺在第一步。将二酰胺氯化以形成反式 - 环己烷-1,4-二羧酸 - 双-N-氯酰胺。然后将后一种化合物用碱金属氢氧化物或碱土金属氢氧化物转化为（a）反式 - 环己烷-1,4-二胺; 或者通过与含有碱金属氢氧化物或碱土金属氢氧化物的反应混合物中的醇或二醇反应形成（b）反式环己烷-1,4-二氨基甲酸酯; 或者通过与含有碱金属氢氧化物或碱土金属氢氧化物的反应混合物中的伯胺或仲胺反应形成（c）反式环己烷-1,4-二脲; 或通过与含有碱金属氢氧化物和二甲基甲酰胺和水的反应混合物中的伯磺酰胺反应而形成（d）反式 - 环己烷-1,4-磺酰脲。（c）中制备的二脲可以在惰性溶剂中用气态氯化氢转化成反式 - 环己烷-1,4-二异氰酸酯。（b）中制备的二氨基甲酸酯和（d）中制备的二磺酰脲可以热分解成反式环己烷-1,4-二异氰酸酯。

87. 发明授权

US4482544A Compounds for treating hypertension 失效
标题翻译：用于治疗高血压的化合物
公开(公告)号：US4482544A
公开(公告)日：1984-11-13
申请号：US445117
申请日：1982-11-29
申请人： Fu-chih Huang , Howard Jones , Wan-Kit Chan
发明人： Fu-chih Huang , Howard Jones , Wan-Kit Chan
IPC分类号： A61K38/55 , A61K38/00 , A61P9/12 , A61P43/00 , C07C67/00 , C07C241/00 , C07C243/34 , C07K5/02 , A61K37/00 , C07C103/52
CPC分类号： C07K5/0222 , C07K5/022 , A61K38/00 , Y10S530/80
摘要： Compounds of the general formula ##STR1## and their pharmaceutically-acceptable salts, wherein the substituents are as defined herein, having antihypertensive activity.
摘要翻译：通式“IMAGE”的化合物及其药学上可接受的盐，其中取代基如本文所定义，具有抗高血压活性。

88. 发明授权

US4467114A Preparation of trans cyclohexane 1,4-diurea 失效
标题翻译：反式环己烷1,4-二脲的制备
公开(公告)号：US4467114A
公开(公告)日：1984-08-21
申请号：US420187
申请日：1982-09-20
申请人： Hans Zengel , Manfred Bergfeld
发明人： Hans Zengel , Manfred Bergfeld
IPC分类号： C07C271/24 , C07C67/00 , C07C209/00 , C07C209/56 , C07C211/36 , C07C231/00 , C07C231/02 , C07C235/58 , C07C239/00 , C07C241/00 , C07C263/06 , C07C265/00 , C07C265/14 , C07C273/18 , C07C275/04 , C07C275/26 , C07C311/56 , C07D295/20 , C07C127/15
CPC分类号： C07C273/1845 , C07C311/56
摘要： A process is disclosed for selectively making trans-cyclohexane-1,4-diisocyanate, trans-cyclohexane-1,4-diamine, a trans-cyclohexane-1,4-diurethane, a trans-cyclohexane-1,4-diurea and trans-cyclohexane-1,4-disulphonyl urea by reacting ammonia with a mixture of cis and trans-cyclohexane-1,4-dicarboxylic acid, a lower alkyl ester, a glycol ester, an oligomeric ester or a polyester to make a solid trans-dicarboxylic acid diamide in a first step. The diamide is chlorinated to form cyclohexane-1,4-dicarboxylic acid-bis-N-chloramide. The latter compound is then converted into a(a) trans-cyclohexane-1,4-diamine with an alkali metal hydroxide or alkaline earth metal hydroxide; or into a(b) a trans-cyclohexane-1,4-diurethane by reaction with an alcohol or glycol in a reaction mixture containing an alkali metal hydroxide or alkaline earth metal hydroxide; or into(c) a trans-cyclohexane-1,4-diurea by reaction with a primary or secondary amine in a reaction mixture containing an alkali metal hydroxide or alkaline earth metal hydroxide; or into a(d) trans-cyclohexane-1,4-sulphonyl urea by reaction with a primary sulphonamide in a reaction mixture containing an alkali metal hydroxide and dimethyl formamide and water.The diurea prepared in (c) may be converted into trans-cyclohexane-1,4-diisocyanate with gaseous hydrogen chloride in an inert solvent. The diurethane prepared in (b) and the disulphonyl urea prepared in (d) may be thermally decomposed into trans-cyclohexane-1,4-diisocyanate.
摘要翻译：公开了一种选择性制备反式环己烷-1,4-二异氰酸酯，反式环己烷-1,4-二胺，反式环己烷-1,4-二氨基甲酸酯，反式环己烷-1,4-二脲和反式环己烷-1,4-二脲通过使氨与顺式和反式 - 环己烷-1,4-二羧酸，低级烷基酯，乙二醇酯，低聚酯或聚酯的混合物反应，形成固体反式 - 环己烷-1,4-二磺酰脲，二羧酸二酰胺。氯化二酰胺以形成环己烷-1,4-二羧酸 - 双-N-氯酰胺。然后将后一种化合物用碱金属氢氧化物或碱土金属氢氧化物转化为（a）反式 - 环己烷-1,4-二胺; 或者通过与含有碱金属氢氧化物或碱土金属氢氧化物的反应混合物中的醇或二醇反应形成（b）反式环己烷-1,4-二氨基甲酸酯; 或者通过与含有碱金属氢氧化物或碱土金属氢氧化物的反应混合物中的伯胺或仲胺反应形成（c）反式环己烷-1,4-二脲; 或通过与含有碱金属氢氧化物和二甲基甲酰胺和水的反应混合物中的伯磺酰胺反应而形成（d）反式 - 环己烷-1,4-磺酰脲。（c）中制备的二脲可以在惰性溶剂中用气态氯化氢转化成反式 - 环己烷-1,4-二异氰酸酯。（b）中制备的二氨基甲酸酯和（d）中制备的二磺酰脲可以热分解成反式环己烷-1,4-二异氰酸酯。

89. 发明授权

US4451485A Treatment of cardio-vascular diseases with 3-(2,2,2-trimethylhydrazinium) propionate dihydrate 失效
标题翻译：用3-（2,2,2-三甲基肼）丙酸酯二水合物治疗心血管疾病
公开(公告)号：US4451485A
公开(公告)日：1984-05-29
申请号：US419454
申请日：1982-09-17
申请人： Ivars Y. Kalvinsh , Alexei V. Vinogradov , Maris M. Veveris , Inna I. Makarova , Anatoly S. Birman , Georgy V. Barmotin , Oleg N. Akifiev
发明人： Ivars Y. Kalvinsh , Alexei V. Vinogradov , Maris M. Veveris , Inna I. Makarova , Anatoly S. Birman , Georgy V. Barmotin , Oleg N. Akifiev
IPC分类号： A61K31/14 , A61K31/15 , A61K31/205 , A61P9/00 , A61P9/06 , A61P43/00 , C07C67/00 , C07C241/00 , C07C243/40
CPC分类号： C07C243/00 , A61K31/15
摘要： A pharmaceutical composition for the treatment of cardio-vascular diseases comprising 3-(2,2,2-trimethylhydrazinium) propionate dihydrate of the following formula:(CH.sub.3).sub.3 N.sup.+ NHCH.sub.2 CH.sub.2 COO.sup.- .multidot.2H.sub.2 Oand a pharmaceutically acceptable diluent.
摘要翻译：一种用于治疗心血管疾病的药物组合物，其包含下式的3-（2,2,2-三甲基肼）丙酸酯二水合物：（CH3）3N + NHCH2CH2COO-x2H2O和药学上可接受的稀释剂。

90. 发明授权

US4446266A N,N'-Bis-salicyloyl-hydrazine as a metal deactivator 失效
标题翻译： N，N'-双 - 水杨酰肼作为金属钝化剂
公开(公告)号：US4446266A
公开(公告)日：1984-05-01
申请号：US173409
申请日：1980-07-29
申请人： Wolfgang von Gentzkow , Roland Rubner
发明人： Wolfgang von Gentzkow , Roland Rubner
IPC分类号： C08L23/00 , C07C67/00 , C07C241/00 , C07C243/38 , C08K5/22 , C08K5/24 , C08K5/25 , C08L7/00 , C08L21/00 , C08L51/00 , C08L51/02 , C08L67/00 , C08L77/00 , C08L101/00 , C09K3/00 , H01B3/20 , H05K3/28
CPC分类号： C08K5/24 , H05K3/282 , H05K3/285
摘要： The invention relates to the use of N,N'-bis-salicyloyl hydrazine as a metal deactivator for organic materials which are in contact with copper or contain copper or copper ions, and has the object of providing an N,N'-bis-salicyloyl hydrazine which allows processing without danger on an industrial scale. For this purpose, the invention provides an N,N'-bis-salicyloyl hydrazine which is prepared from salicylic-acid alkyl ester and either hydrazine or salicylic-acid hydrazide. N,N'-bis-salicyloyl hydrazine prepared in this manner serves particularly as a metal deactivator in cable and wire insulation for power and communications engineering.
摘要翻译：本发明涉及N，N'-双 - 水杨酰肼作为与铜接触或含有铜或铜离子的有机材料的金属钝化剂的用途，其目的是提供N，N'-双 - 水飞蓟肼，允许在工业规模上无危险地加工。为此，本发明提供由水杨酸烷基酯和肼或水杨酸酰肼制备的N，N'-双 - 水杨酰肼。以这种方式制备的N，N'-二 - 水杨酰肼特别用作用于电力和通信工程的电缆和电线绝缘中的金属钝化剂。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式