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    • 2. 发明授权
    • Prophylactic/therapeutic agents for lifestyle-related diseases
    • 生活方式相关疾病的预防/治疗药物
    • US08623909B2
    • 2014-01-07
    • US12991155
    • 2009-05-08
    • Hajime NawataToshihiko YanaseTakayoshi Nakagawa
    • Hajime NawataToshihiko YanaseTakayoshi Nakagawa
    • C07D311/78A61K31/35
    • A61K31/57A61K31/56G01N33/5044G01N33/689G01N33/6893G01N33/74G01N2800/02G01N2800/042G01N2800/044G01N2800/321
    • Disclosed is a method for screening a compound having an activity that selectively modulates an androgen receptor, comprising a step of measuring the mRNA expression level of prostate-specific antigen or the production level of prostate-specific antigen in prostate cancer cells by contacting a test substance with the prostate cancer cells, and a step of measuring the mRNA expression level of uncoupling protein 1 or the production level of uncoupling protein 1 in adipocytes by contacting a test substance with the adipocytes. Additionally disclosed is a selective androgen receptor modulator, comprising as an active ingredient thereof a compound represented by any of structural formulas (I) to (III), and a composition for preventing or treating a lifestyle-related disease, comprising as an active ingredient thereof said selective androgen receptor modulator.
    • 公开了一种筛选具有选择性调节雄激素受体活性的化合物的方法,包括通过使测试物质接触测量前列腺癌细胞中前列腺特异性抗原的mRNA表达水平或前列腺特异性抗原的产生水平的步骤 与前列腺癌细胞,以及通过使测试物质与脂肪细胞接触来测量解偶联蛋白1的mRNA表达水平或脂肪细胞中解偶联蛋白1的产生水平的步骤。 另外公开了一种选择性雄激素受体调节剂,其包含作为其活性成分的由结构式(I)至(III)中任一项表示的化合物和用于预防或治疗与生活方式有关的疾病的组合物,其包含作为其活性成分 所述选择性雄激素受体调节剂。
    • 3. 发明授权
    • Distortion correcting device
    • 失真校正装置
    • US08537039B2
    • 2013-09-17
    • US13409516
    • 2012-03-01
    • Junya MatsunoTetsuro Itakura
    • Junya MatsunoTetsuro Itakura
    • H03M1/06
    • H03M1/0614H03M1/12H03M1/1225
    • There is provided a distortion correcting device in which a first A/D converter A/D converts a first input signal to obtain a first converted signal, a second A/D converter A/D converts a second input signal to obtain a second converted signal wherein the second input signal is a signal obtained by reducing an amplitude of the first input signal, or the first input signal is a signal obtained by increasing an amplitude of the second input signal, the exponentiator obtains an exponential signal by raising the second converted signal to an n-th power (“n” is an integer of 2 or more), a adaptive correlation controller carries out adaptive correlation control based on the exponential signal and the second converted signal to generate a distortion signal that is an n-th power component contained in the exponential signal, and a distortion remover removes the distortion signal from the first converted signal.
    • 提供了一种失真校正装置,其中第一A / D转换器A / D转换第一输入信号以获得第一转换信号,第二A / D转换器A / D转换第二输入信号以获得第二转换信号 其中所述第二输入信号是通过减小所述第一输入信号的幅度获得的信号,或者所述第一输入信号是通过增加所述第二输入信号的幅度而获得的信号,所述指数器通过提高所述第二转换信号来获得指数信号 到“n”次幂(“n”是2以上的整数)时,自适应相关控制器根据指数信号和第二转换信号进行自适应相关控制,生成作为第n次方的失真信号 分量包含在指数信号中,并且失真去除器从第一转换信号中去除失真信号。
    • 5. 发明授权
    • Display drive apparatus, display apparatus and drive method therefor
    • 显示驱动装置,显示装置及其驱动方法
    • US08497854B2
    • 2013-07-30
    • US12079887
    • 2008-03-28
    • Jun Ogura
    • Jun Ogura
    • G09G5/00
    • G09G3/3275G09G2320/0295
    • A display drive apparatus includes a detection voltage applying circuit that applies a predetermined detection voltage to the drive element of the pixel drive circuit, a voltage detecting circuit that detects a voltage value corresponding to a device characteristic unique to the drive element after a predetermined time elapses after the application of the detection voltage to the drive element by the pixel drive circuit, and a gradation designating signal generating circuit that generates a gradation designating signal based on an absolute value of a voltage component according to a gradation value of display data and a value, acquired by multiplying an absolute value of the voltage value detected by the voltage detecting circuit, by a constant greater than 1, and applies the gradation designating signal to the pixel drive circuit, whereby a change in device characteristic.
    • 一种显示驱动装置,具备:对上述像素驱动电路的驱动元件施加规定的检测电压的检测电压施加电路;检测与上述驱动元件特有的装置特性对应的电压值,经过规定时间后, 在通过像素驱动电路向驱动元件施加检测电压之后,根据显示数据的灰度值,根据电压分量的绝对值生成灰度指定信号的灰度指定信号生成电路, 通过将由电压检测电路检测的电压值的绝对值乘以大于1的常数获得的,并且将渐变指定信号施加到像素驱动电路,从而改变器件特性。
    • 6. 发明授权
    • Image pickup device having abnormality warning function based on brightness dispersions of two picked-up images, and warning method and recording medium for the same
    • 具有基于两个拍摄图像的亮度分散的异常警告功能的图像拾取装置,以及用于其的警告方法和记录介质
    • US08488041B2
    • 2013-07-16
    • US13018490
    • 2011-02-01
    • Mitsuyasu NakajimaMasaaki Kikuchi
    • Mitsuyasu NakajimaMasaaki Kikuchi
    • H04N5/222
    • H04N5/228H04N5/2171
    • An image pickup control unit displays either one of a picked-up image by a first image pickup unit and a picked-up image by a second image pickup unit on a display unit as a finder image. A feature detecting unit calculates a distribution of brightness values or brightness dispersion for each of the picked-up images by the first and second image pickup units, thereby detecting features of the two picked-up images. A sameness determining unit determines the sameness between both picked-up images based on the detected features, and determines that an abnormality like the unexpected appearance of an obstacle is present when the feature largely differs. When it is determined that an abnormality is present, a warning processing unit simultaneously displays both picked-up images on the display unit, or displays the picked-up image including the abnormality on the display unit as a finder image.
    • 图像拾取控制单元作为取景器图像,通过第一图像拾取单元将拾取的图像和由第二图像拾取单元拾取的图像显示在显示单元上。 特征检测单元通过第一和第二图像拾取单元计算每个拍摄图像的亮度值或亮度色散的分布,从而检测两个拾取图像的特征。 同一性确定单元基于检测到的特征来确定两个拾取图像之间的相同性,并且当特征很大程度上不同时,确定出现像障碍物的意外外观那样的异常。 当确定存在异常时,警告处理单元同时在显示单元上显示所拾取的图像,或者在显示单元上显示包括异常的拍摄图像作为取景器图像。
    • 7. 发明授权
    • Method of connecting printed circuit boards and corresponding arrangement
    • 连接印刷电路板的方法和相应的布置
    • US08482928B2
    • 2013-07-09
    • US12587978
    • 2009-10-15
    • Simone CapeletoChristian Hacker
    • Simone CapeletoChristian Hacker
    • H05K1/00H05K1/14
    • H05K1/148H05K3/0061H05K3/361H05K2201/09027H05K2201/09745H05K2201/10106
    • Connecting a first (12) and a second (14) printed circuit board or PCB carrying a LED lighting source (10) and the associated drive circuitry involves providing board connection pads (12a, 14a) at said first (12) and second (14) PCBs, and arranging a flex PCB (16) in a bridge-like fashion between the first (12) and second (14) PCBs. The flex PCB (16) has connection pads (16a) for bonding with the board connection pads (12a, 14a) of the PCBs (12, 14). The connection pads (16a) in the flex PCB (16) arranged in a bridge-like fashion between the first (12) and second (14) PCBs are bonded with the connection pads (12a, 14a) of the first (12) and second (14) PCBs, so that the first (12) and second (14) PCBs are connected.
    • 连接携带LED照明源(10)的第一(12)和第二(14)印刷电路板或PCB以及相关联的驱动电路包括在所述第一(12)和第二(14)处提供板连接焊盘(12a,14a) )PCB,并且在第一(12)和第二(14)PCB之间布置以桥状形式的柔性PCB(16)。 柔性PCB(16)具有用于与PCB(12,14)的板连接焊盘(12a,14a)接合的连接焊盘(16a)。 在第一(12)和第二(14)PCB之间以桥状排列的柔性PCB(16)中的连接焊盘(16a)与第一(12)和第二(14)PCB的连接焊盘(12a,14a) 第二(14)个PCB,使得第一(12)和第二(14)个PCB连接。
    • 8. 发明授权
    • Electronic calculator and method of controlling the calculator
    • 电子计算器和计算器的控制方法
    • US08482531B2
    • 2013-07-09
    • US12145874
    • 2008-06-25
    • Kosuke Karoji
    • Kosuke Karoji
    • G06F3/041G06F15/02
    • G09B19/0053
    • An electronic calculator is very useful for learning manipulation procedure to perform a predetermined process by designating a position on a display screen of the calculator. Manipulation is executed on a touch screen 16a of the display screen with a touch pen. When a function expression is entered to execute a process for displaying a graphic, a position and content of manipulation in each manipulating process are previously recorded in an external recording medium 13 in association with the order of manipulation. Thereafter, the position and content of manipulation are read from the external recording medium 13 every manipulation to display the position of manipulation and a mark indicating the content of the manipulation, thereby instructing manipulation to be executed. When touch manipulation is executed as instructed, a process is performed to enter the function expression and display a graphic, and manipulation to be executed in the following order of manipulation is displayed on the display screen.
    • 电子计算器对于通过指定计算器的显示屏幕上的位置来执行预定处理的学习操作过程非常有用。 用触摸笔在显示屏的触摸屏16a上执行操作。 当输入功能表达式以执行用于显示图形的处理时,每个操作处理中的操作的位置和内容与操作顺序相关联地预先记录在外部记录介质13中。 此后,每次操作从外部记录介质13读取操作的位置和内容,以显示操作位置和指示操作内容的标记,从而指示执行操作。 当按照指示执行触摸操作时,执行进入功能表达并显示图形的处理,并且在显示屏幕上显示按照以下操作顺序执行的操纵。
    • 9. 发明授权
    • Hand grip member with electric heater
    • 带电加热器的手柄部件
    • US08481889B2
    • 2013-07-09
    • US12088543
    • 2006-09-29
    • Satoru FujiwaraKouzou SasakiYuichi Fukuda
    • Satoru FujiwaraKouzou SasakiYuichi Fukuda
    • H05B3/06H05B3/40B62K21/26B62J33/00
    • B62J33/00B62K21/26H05B3/46Y10T74/20828
    • A handle grip member with electric heater can be produced in high yield through simple processing not using any core of synthetic resin and avoiding molding operation. Depressed groove (4) is spirally provided on an external surface of inner part (1) of rubber, and multiple ribs (5) are provided on an internal surface thereof along the direction of length. Electric heater (7) of tape-shaped metal conductor is implanted in the depressed groove (4), and fixed. Electric wires (8a,8b) are connected to two ends of the electric heater (7) and drawn out. The inner part (1) is inserted in outer part (9) of rubber tube, and the outer part (9) is fixed to the inner part (1) with the use of an adhesive, etc.
    • 具有电加热器的把手部件可以通过简单的加工而不用任何合成树脂芯并且避免成型操作而以高产率生产。 凹槽(4)螺旋地设置在橡胶的内部部分(1)的外表面上,并且沿其长度方向在其内表面上设置多个肋(5)。 将带状金属导体的电加热器(7)注入凹槽(4)中并固定。 电线(8a,8b)连接到电加热器(7)的两端并拉出。 内部部分(1)插入橡胶管的外部部分(9)中,外部部分(9)通过使用粘合剂等固定到内部部分(1)上。