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1. 发明授权

US08741567B2 Composition and methods related to modification of 5-hydroxymethylcytosine (5-hmC) 有权
标题翻译：与5-羟甲基胞嘧啶（5-hmC）修饰相关的组成和方法
公开(公告)号：US08741567B2
公开(公告)日：2014-06-03
申请号：US13095505
申请日：2011-04-27
申请人： Chuan He , Chunxiao Song
发明人： Chuan He , Chunxiao Song
IPC分类号： C12Q1/68 , C07H21/00
CPC分类号： C12Q1/6883 , C12P19/34 , C12Q1/48 , C12Q1/6827 , C12Q2600/154 , C12Y204/01028 , C12Q2521/531 , C12Q2537/164
摘要： The present invention relates generally to the field of molecular biology. More particularly, it concerns methods and compositions for detecting, evaluating, and/or mapping 5-hydroxymethyl-modified cytosine bases within a nucleic acid molecule.
摘要翻译：本发明一般涉及分子生物学领域。更具体地，涉及用于在核酸分子内检测，评估和/或测定5-羟甲基修饰的胞嘧啶碱基的方法和组合物。

2. 发明授权

US07546761B2 Diesel oxidation catalyst (DOC) temperature sensor rationality diagnostic 有权
标题翻译：柴油氧化催化剂（DOC）温度传感器合理性诊断
公开(公告)号：US07546761B2
公开(公告)日：2009-06-16
申请号：US11385045
申请日：2006-03-17
申请人： Chuan He , Richard B. Jess , Jay Tolsma , GuoJun Shi , Jose L. DeLeon , Kouji Sakumoto
发明人： Chuan He , Richard B. Jess , Jay Tolsma , GuoJun Shi , Jose L. DeLeon , Kouji Sakumoto
IPC分类号： G01M15/10
CPC分类号： F01N11/005 , F01N3/0231 , F01N3/035 , F01N2560/02 , F02B37/00 , Y02T10/47
摘要： A temperature sensor rationality control system for an exhaust treatment system having an oxidation catalyst includes an oxidation catalyst inlet temperature sensor that generates an inlet temperature signal and an oxidation catalyst outlet temperature sensor that generates an outlet temperature signal. A control module determines whether a difference based on the inlet temperature signal and the outlet temperature signal is below a difference threshold when an exhaust temperature is within a threshold range.
摘要翻译：具有氧化催化剂的废气处理系统的温度传感器合理性控制系统包括产生入口温度信号的氧化催化剂入口温度传感器和产生出口温度信号的氧化催化剂出口温度传感器。当排气温度在阈值范围内时，控制模块确定基于入口温度信号和出口温度信号的差异是否低于差值阈值。

3. 发明申请

US20090025367A1 Physical based LNT regeneration strategy 失效
标题翻译：基于物理的LNT再生策略
公开(公告)号：US20090025367A1
公开(公告)日：2009-01-29
申请号：US11880950
申请日：2007-07-25
申请人： James Edward McCarthy, JR. , Chuan He
发明人： James Edward McCarthy, JR. , Chuan He
IPC分类号： F01N3/20
CPC分类号： F01N3/0885 , B01D53/9409 , B01D53/9495 , B01D2251/208 , B01D2258/012 , F01N3/0814 , F01N3/0871 , F01N3/2073 , F01N3/208 , F01N13/0097 , F01N2240/30 , F01N2560/026 , F01N2610/03 , F01N2610/146 , F01N2900/1621 , Y02T10/24
摘要： A lean NOX trap is a diesel exhaust aftertreatment system is selectively denitrated in a manner that addresses unreliability of NOX sensor data. According to one concept, data from a NOX is ignored or given decreased weight in a period immediately following a denitration. According to another concept, denitration is made contingent on both a first and a second criteria being met. The first criteria relates to the amount of NOX stored in the LNT or remaining NOX storage capacity of the LNT. The second criteria relates to the current performance of the exhaust treatment system, or a portion thereof, as determined from one or more measurements of NOX concentration in the exhaust. This reduces premature denitrations and associated unnecessary fuel expenditures resulting from inaccurate NOX concentration data and transient events
摘要翻译：精益NOX捕集器是以解决NOX传感器数据的不可靠性的方式选择性地脱硝柴油机排气后处理系统。根据一个概念，来自NOX的数据被忽略，或者在脱氮之后的时间段内减轻重量。根据另一个概念，脱硝是根据符合第一和第二标准而进行的。第一个标准涉及储存在LNT中的NOX量或LNT的剩余NOX储存容量。第二标准涉及排气处理系统的当前性能，或其一部分，其根据排气中的一氧化氮浓度的一个或多个测量结果确定。这可以减少由于不准确的NOX浓度数据和瞬态事件导致的过早脱硝和相关的不必要的燃料费用

4. 发明授权

US06185051B2 High numerical aperture optical focusing device for use in data storage systems 有权
标题翻译：用于数据存储系统的高数值孔径光学聚焦装置
公开(公告)号：US06185051B2
公开(公告)日：2001-02-06
申请号：US09338785
申请日：1999-06-23
申请人： Hong Chen , Chuan He , Charles C. K. Cheng , Joseph J. Miceli, Jr.
发明人： Hong Chen , Chuan He , Charles C. K. Cheng , Joseph J. Miceli, Jr.
IPC分类号： G02B1318
CPC分类号： B82Y10/00 , G11B7/122 , G11B7/1374 , G11B7/1387 , G11B11/10534 , G11B11/10543 , G11B11/10554 , G11B11/1058 , G11B2007/13725
摘要： A near-field optical or MO data storage system uses an optical focusing device for focusing an incident optical beam to a small size focal spot. The optical focusing device includes an optically transmissive body which is defined by a generally flat incident surface, a flat, bottom surface disposed opposite and parallel to the incident surface, and a reflective side coated with a reflective layer for reflecting the optical beam through the body toward the bottom surface. The bottom surface defines a focal plane on which the focal spot is formed, for generating a localized evanescent field. The focal spot is located along a central axis P, in very close proximity to the data storage disk, such that the localized evanescent field interacts with the disk, for enabling data to be transduced to and from the disk by effecting near field coupling. An electro-magnetic coil or coil assembly, can optionally be formed on the bottom surface, co-axially with the focal spot, for generating a desired write magnetic field. The reflective side of the optical focusing device preferably has a parabola shaped curvature, but other shapes can alternatively be selected. For example, the side curvature can have a tilted parabola shape.
摘要翻译：近场光学或MO数据存储系统使用光聚焦装置将入射光束聚焦到小尺寸焦点。该光学聚焦装置包括光学透射体，其由大致平坦的入射表面，与入射表面相对并平行设置的平坦的底表面限定，反射面涂覆有反射层，用于将光束反射通过本体朝向底面。底表面限定焦平面，焦平面形成在其上，用于产生局部渐逝场。焦点沿着中心轴P位于数据存储盘非常接近处，使得局部的消逝场与磁盘相互作用，以通过进行近场耦合使数据能够被传送到磁盘。电磁线圈或线圈组件可以可选地形成在底表面上，与焦斑同轴地形成，以产生所需的写入磁场。光学聚焦装置的反射侧优选地具有抛物线形曲率，但是也可以选择其它形状。例如，侧曲率可以具有倾斜的抛物线形状。

5. 发明授权

US6130779A Near field magneto-optical head made using wafer processing techniques 失效
标题翻译：使用晶片处理技术制造的近场磁光头
公开(公告)号：US6130779A
公开(公告)日：2000-10-10
申请号：US111098
申请日：1998-07-06
申请人： Carl J. Carlson , Joseph Miceli, Jr. , Hong Chen , Chuan He , Charles C-K Cheng , Ross W Stovall
发明人： Carl J. Carlson , Joseph Miceli, Jr. , Hong Chen , Chuan He , Charles C-K Cheng , Ross W Stovall
IPC分类号： G02B5/18 , G11B7/135 , G11B7/22 , G11B11/105 , G11B7/00 , G11B5/27
CPC分类号： G11B11/10554 , B82Y10/00 , G02B5/1876 , G02B5/1885 , G11B11/10532 , G11B7/1353 , G11B11/1058 , G11B7/22
摘要： The method of making and self-aligning a magneto-optical head at a wafer level is as follows: A flat optical substrate is molded or heat pressed in batches as a wafer level to form the desired lens shapes. Coil cavities or depressions are simultaneously formed with the lens to accommodate the coil assembly. Conductive plugs are formed in proximity to the cutting lines, for wire bonding attachment to the coil. The plugs are filled with a conductive material such as copper. The plugs do not extend through the entire depth of the optical wafer, thus further facilitating the mass production of the integrated heads. The slider body wafer is formed from silicon or other appropriate material. The slider body wafer and the lens/coil wafer are bonded. Coils and pedestals are formed on the lens / coil plate using thin-film processing techniques. Reflective surfaces are deposited on the bottom surface of the substrate, opposite the lens. The mirror material around the pedestal areas and plugs is masked and removed. An alumina layer is then deposited to define the air bearing surface and the pedestal. Yokes are then formed by means of lithography and plating in the base and sides of the depressions to assume a desired shape. A series of alternating insulating layers and conductive coil layers is formed. A protective layer seals the coil assembly, and is lapped to correct the lens thickness and to provide proper focal plane.
摘要翻译：在晶片级别制造和自动对准磁光头的方法如下：平板光学基板被成型或成批地热压成晶片级以形成所需的透镜形状。线圈腔或凹陷部分与透镜同时形成以容纳线圈组件。导电插塞形成在切割线附近，用于与线圈的引线接合。塞子填充有诸如铜的导电材料。插头不延伸穿过光学晶片的整个深度，从而进一步促进了集成头的批量生产。滑块体晶片由硅或其它合适的材料形成。滑块体晶片和透镜/线圈晶片接合。使用薄膜加工技术在透镜/线圈板上形成线圈和基座。反射表面沉积在基底的与透镜相对的底表面上。底座区域和插头周围的镜子材料被遮蔽并移除。然后沉积氧化铝层以限定空气轴承表面和基座。然后通过在凹部的基部和侧面中的光刻和电镀形成轭以呈现期望的形状。形成一系列交替绝缘层和导电线圈层。保护层密封线圈组件，并且被研磨以校正透镜厚度并提供适当的焦平面。

6. 发明授权

US09666426B2 Methods and apparatus for uniformly metallization on substrates 有权
公开(公告)号：US09666426B2
公开(公告)日：2017-05-30
申请号：US14127285
申请日：2011-06-24
申请人： Hui Wang , Yue Ma , Chuan He , Xi Wang
发明人： Hui Wang , Yue Ma , Chuan He , Xi Wang
IPC分类号： C25D7/12 , C25D5/20 , H01L21/02 , C25D17/00 , C25D5/08 , C25D5/18 , C25D17/06 , C25D21/10
CPC分类号： C25D21/10 , C25D5/08 , C25D5/18 , C25D5/20 , C25D7/12 , C25D7/123 , C25D17/00 , C25D17/001 , C25D17/002 , C25D17/008 , C25D17/06 , H01L21/02 , H01L21/67138
摘要： An apparatus for substrate metallization from electrolyte is provided. The apparatus comprises: an immersion cell containing metal salt electrolyte; at least one electrode connecting to at least one power supply; an electrically conductive substrate holder holding at least one substrate to expose a conductive side of the substrate to face the at least one electrode; an oscillating actuator for oscillating the substrate holder with an amplitude and a frequency; at least one ultrasonic device with an operating frequency and an intensity, disposed in the metallization apparatus; at least one ultrasonic power generator connecting to the ultrasonic device; at least one inlet for metal slat electrolyte feeding; and at least one outlet for metal salt electrolyte draining.

7. 发明申请

US20140322707A1 COMPOSITION AND METHODS RELATED TO MODIFICATION OF 5-METHYLCYTOSINE (5-mC) 有权
标题翻译：与5-甲基喹啉（5-mC）的改性相关的组合物和方法
公开(公告)号：US20140322707A1
公开(公告)日：2014-10-30
申请号：US14110007
申请日：2012-04-06
申请人： Chuan He , Liang Zhang , Xingyu Lu
发明人： Chuan He , Liang Zhang , Xingyu Lu
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6869 , C12Q1/6827 , C12Q2521/531 , C12Q2537/164
摘要： The present invention relates to methods and compositions for detecting, evaluating, and/or mapping 5-methyl-modified and/or 5-hydroxylmethyl-modified cytosine bases within a nucleic acid molecule.
摘要翻译：本发明涉及用于检测，评估和/或测定核酸分子内的5-甲基修饰和/或5-羟甲基修饰的胞嘧啶碱基的方法和组合物。

8. 发明授权

US08383429B2 Method and apparatus for thermal treatment of semiconductor workpieces 有权
标题翻译：半导体工件热处理方法和装置
公开(公告)号：US08383429B2
公开(公告)日：2013-02-26
申请号：US12733436
申请日：2007-08-29
申请人： Yue Ma , Chuan He , Zhenxu Pang , David Wang , Voha Nuch
发明人： Yue Ma , Chuan He , Zhenxu Pang , David Wang , Voha Nuch
IPC分类号： H01L21/00
CPC分类号： H01L21/324 , F27B17/0025 , H01L21/67109 , H01L21/6719
摘要： The present invention provides an apparatus and method for rapid and uniform thermal treatment of semiconductor workpieces in two closely arranged thermal treatment chambers with a retractable door between them. The retractable door moves in between two thermal treatment chambers during heating or cooling process, and additional heating and cooling sources are provided for double-side thermal treatment of the semiconductor workpiece.
摘要翻译：本发明提供了一种用于在两个紧密布置的热处理室中快速均匀地热处理半导体工件的装置和方法，其间具有可伸缩门。可伸缩门在加热或冷却过程中在两个热处理室之间移动，并且为半导体工件的双面热处理提供附加的加热和冷却源。

9. 发明申请

US20110301045A1 Composition and Methods Related to Modification of 5-Hydroxymethylcytosine (5-hmC) 有权
标题翻译：与5-羟甲基胞嘧啶（5-hmC）修饰相关的组成和方法
公开(公告)号：US20110301045A1
公开(公告)日：2011-12-08
申请号：US13095505
申请日：2011-04-27
申请人： Chuan He , Liang Zhang , Chunxiao Song
发明人： Chuan He , Liang Zhang , Chunxiao Song
IPC分类号： C12Q1/68 , C40B30/00
CPC分类号： C12Q1/6883 , C12P19/34 , C12Q1/48 , C12Q1/6827 , C12Q2600/154 , C12Y204/01028 , C12Q2521/531 , C12Q2537/164
摘要： The present invention relates generally to the field of molecular biology. More particularly, it concerns methods and compositions for detecting, evaluating, and/or mapping 5-hydroxymethyl-modified cytosine bases within a nucleic acid molecule.
摘要翻译：本发明一般涉及分子生物学领域。更具体地，涉及用于在核酸分子内检测，评估和/或测定5-羟甲基修饰的胞嘧啶碱基的方法和组合物。

10. 发明授权

US08036814B2 Calibration scheme for an exhaust gas sensor 有权
标题翻译：废气传感器的校准方案
公开(公告)号：US08036814B2
公开(公告)日：2011-10-11
申请号：US12409231
申请日：2009-03-23
申请人： Dave Charles Weber , David John Kubinski , Chuan He , Michiel J. Van Nieuwstadt
发明人： Dave Charles Weber , David John Kubinski , Chuan He , Michiel J. Van Nieuwstadt
IPC分类号： F02D45/00 , F01N11/00
CPC分类号： F01N11/00 , F01N2560/025 , F01N2560/026 , F02D41/123 , F02D41/1452 , F02D41/1454 , F02D41/1456 , F02D41/1459 , F02D41/146 , F02D41/1462 , F02D41/2416 , F02D41/2454 , F02D2041/1433 , F02D2041/1468 , Y02T10/47
摘要： Various systems and methods are described for controlling an engine in a vehicle in response to an equilibrium value of an exhaust gas constituent generated from an exhaust gas sensor. One example method comprises during engine fueling below a threshold amount where at least one intake valve and one exhaust valve of the engine are operating: generating an equilibrium value of an exhaust gas constituent reading of the exhaust gas sensor, the equilibrium value based on a trajectory of the exhaust gas constituent reading, and under selected engine combusting conditions, adjusting the sensor signal based on the equilibrium value.
摘要翻译：描述了用于响应于从废气传感器产生的排气成分的平衡值来控制车辆中的发动机的各种系统和方法。一个示例性方法包括在发动机加油期间低于阈值量，其中发动机的至少一个进气门和一个排气阀正在操作：产生排气传感器的排气构成读数的平衡值，基于轨迹的平衡值的废气成分读数，并且在选择的发动机燃烧条件下，基于平衡值调节传感器信号。

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