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    • 8. 发明授权
    • Method for producing optically active alcohols or carboxylic acids
    • 光学活性醇或羧酸的制备方法
    • US07507866B2
    • 2009-03-24
    • US10589049
    • 2005-02-08
    • Heiko UrtelMarkus RöschAndrea HaunertMarkus Schubert
    • Heiko UrtelMarkus RöschAndrea HaunertMarkus Schubert
    • C07C31/18C07C53/00
    • C07C29/149C07B41/02C07B53/00C07B2200/07C07C213/00C07D307/33C07C215/08C07C215/10C07C215/18C07C215/28C07C31/22C07C31/207C07C31/205C07C31/36C07C31/20C07C31/12
    • The present invention relates to a process for preparing optically active hydroxy-, alkoxy-, amino-, alkyl-, aryl- or chlorine-substituted alcohols or hydroxy carboxylic acids having from 3 to 25 carbon atoms or their acid derivatives or cyclization products by hydrogenating the correspondingly substituted optically active mono- or dicarboxylic acids or their acid derivatives in the presence of a catalyst whose active component consists of rhenium or of rhenium and comprises at least one further element having an atomic number of from 22 to 83, with the provisos that a. the at least one further element having an atomic number of from 22 to 83 is not ruthenium and b. in the case of the preparation of optically active 2-amino-, 2-chloro-, 2-hydroxy- and 2-alkoxy-1-alkanols by catalytically hydrogenating corresponding optically active 2-aminocarboxylic acids, 2-chlorocarboxylic acids, 2-hydroxycarboxylic acids and 2-alkoxycarboxylic acids or their acid derivatives, the at least one further element having an atomic number of from 22 to 83 is not palladium or platinum.
    • 本发明涉及通过氢化制备光学活性羟基,烷氧基 - ,氨基 - ,烷基 - ,芳基 - 或氯取代的醇或具有3至25个碳原子的羟基羧酸或其酸衍生物或环化产物的方法 相应地取代的光学活性单羧酸或二羧酸或其酸衍生物在其活性组分由铼或铼组成的催化剂存在下,并且包含至少一种原子序数为22至83的另外的元素,条件是 一个。 原子序数为22〜83的至少一个以上的元素不是钌,而是b。 在通过催化氢化相应的光学活性2-氨基羧酸,2-氯羧酸,2-羟基羧酸的2-氨基 - ,2-氯 - ,2-羟基 - 和2-烷氧基-1-链烷醇的制备 酸和2-烷氧基羧酸或其酸衍生物,原子序数为22至83的至少一种另外的元素不是钯或铂。