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1. 发明申请

US20070073229A1 Dispenser Components And Methods For Patient Infusion Device 审中-公开
标题翻译：用于患者输液装置的分配器组件和方法
公开(公告)号：US20070073229A1
公开(公告)日：2007-03-29
申请号：US11554248
申请日：2006-10-30
申请人： William Gorman , John Garibotto , J. Flaherty , John Bussiere , Gaurav Rohatgi
发明人： William Gorman , John Garibotto , J. Flaherty , John Bussiere , Gaurav Rohatgi
IPC分类号： A61M37/00
CPC分类号： A61M5/14276 , A61M5/1452 , A61M2005/14208 , A61M2005/14573 , A61M2205/0266 , A61M2205/3365 , A61M2205/3523
摘要： A device for delivering fluid to a patient including an exit port assembly, a reservoir including a side wall extending towards an outlet connected to the exit port assembly, a threaded lead screw received at least partly in the reservoir and longitudinally extending towards the outlet, and a plunger secured to the lead screw and having an outer periphery linearly slideable along the side wall of the reservoir. A tube is coaxially received on the lead screw and includes a longitudinal slot, a pin extending through the lead screw and the slot of the tube, and a gear is secured to the tube for rotation therewith.
摘要翻译：一种用于将流体输送到患者的装置，包括出口端口组件，储存器，包括朝向连接到出口端口组件的出口延伸的侧壁;至少部分地容纳在储存器中并且朝向出口纵向延伸的螺纹导螺杆;以及柱塞，其固定到所述导螺杆上，并且具有沿所述储存器的侧壁可直线滑动的外周。管被同轴地容纳在导螺杆上并且包括纵向狭槽，延伸穿过导螺杆的销和管的狭槽，并且齿轮固定到管上以与其一起旋转。

2. 发明申请

US20060282290A1 Components and Methods For Patient Infusion Device 审中-公开
标题翻译：患者输液装置的组件和方法
公开(公告)号：US20060282290A1
公开(公告)日：2006-12-14
申请号：US11467205
申请日：2006-08-25
申请人： J. Flaherty , William Gorman , John Garibotto , John Bussiere , Matthew Abelson , David Chastain
发明人： J. Flaherty , William Gorman , John Garibotto , John Bussiere , Matthew Abelson , David Chastain
IPC分类号： G06Q10/00 , G06Q50/00
CPC分类号： A61M5/1454 , A61M5/14248 , A61M5/158 , A61M2005/14252 , A61M2005/1583 , A61M2005/1585 , A61M2205/0266 , G06Q50/22
摘要： A fluid delivery device including a housing, a reservoir positioned within the housing, and a transcutaneous access tool positioned within the housing and including, a cannula in fluid communication with the reservoir and linearly moveable along an axis of the transcutaneous access tool through a port in a wall of the housing, a deployment member secured to the cannula and movable along the axis of the transcutaneous access tool against the wall of the housing defining the port, and an annular seal coaxially positioned about the cannula and positioned between the deployment member and the wall of the housing defining the port, so that the seal provides a substantially fluid-tight seal between the deployment member and the wall of the housing when the deployment member is moved against the wall of the housing.
摘要翻译：流体输送装置，其包括壳体，位于壳体内的储存器和定位在壳体内的经皮通路工具，并且包括：与贮液器流体连通的套管，其可沿着经皮通道工具的轴线通过口所述壳体的壁，固定到所述套管并且可沿所述经皮通道工具的轴线移动的展开构件抵靠限定所述端口的所述壳体的壁，以及围绕所述插管同轴定位并且定位在所述展开构件和所述插入件之间的环形密封件所述壳体限定所述端口，使得当所述展开构件抵靠所述壳体的壁移动时，所述密封件在所述展开构件和所述壳体的壁之间提供基本上流体密封的密封。

3. 发明申请

US20050203461A1 TRANSCUTANEOUS FLUID DELIVERY SYSTEM 有权
标题翻译： TRANSCUTANEOUS流体输送系统
公开(公告)号：US20050203461A1
公开(公告)日：2005-09-15
申请号：US10907113
申请日：2005-03-21
申请人： J. Flaherty , William Gorman , John Garibotto , Timothy Wood , Patrick Gutelius
发明人： J. Flaherty , William Gorman , John Garibotto , Timothy Wood , Patrick Gutelius
IPC分类号： A61M5/20 , A61M20060101 , A61M5/00 , A61M5/142 , A61M5/178 , A61M5/31 , A61M37/00
CPC分类号： A61M5/14248 , A61M2005/14252 , A61M2005/1426 , A61M2205/0266 , A61M2205/3592
摘要： A device for delivering fluid to a person including a reservoir for containing a fluid to be delivered to the person, a fluid transport device for dispensing fluid from said reservoir to the person, said fluid transport device including a proximal end in fluid communication with said reservoir and a distal end having a penetrating member for piercing the skin of the person to facilitate the delivery of fluid to the person through the fluid transport device, a housing containing said reservoir and said fluid transport device, said housing including an exit port for receiving said distal end of said fluid transport device upon injection of said distal end into said person and means for securing a first wall of said housing to the skin of the person, a injection activation device including a driving mechanism contacting said fluid transport device for driving said penetrating member from a first position within said housing, through said exit port to a second position, external to said housing and into the skin of said person, and an electrically driven actuator for activating said driving mechanism.
摘要翻译：一种用于将流体输送到包括用于容纳要输送到人的流体的储存器的人的装置，用于将流体从所述储存器分配给人的流体输送装置，所述流体输送装置包括与所述储存器流体连通的近端以及远端，其具有用于刺穿人的皮肤的穿透构件，以便于通过流体输送装置向人传送流体;容纳所述储存器和所述流体输送装置的壳体，所述壳体包括用于接收所述流体所述流体输送装置的远端在将所述远端注射到所述人体中时，以及用于将所述壳体的第一壁固定到人的皮肤的装置，包括驱动机构的喷射启动装置，所述驱动机构接触所述流体输送装置，构件从所述壳体内的第一位置通过所述出口到第二位置，在所述孔的外部使用和进入所述人的皮肤，以及用于启动所述驱动机构的电驱动致动器。

4. 发明授权

US07955343B2 Methods and apparatus for blocking flow through blood vessel 有权
标题翻译：阻塞流经血管的方法和装置
公开(公告)号：US07955343B2
公开(公告)日：2011-06-07
申请号：US11924758
申请日：2007-10-26
申请人： Joshua Makower , J. Christopher Flaherty , Timothy Machold , Jason Whitt , Philip Evard , Patrick Macaulay , John Garibotto , Marc Jensen
发明人： Joshua Makower , J. Christopher Flaherty , Timothy Machold , Jason Whitt , Philip Evard , Patrick Macaulay , John Garibotto , Marc Jensen
IPC分类号： A61B17/34
CPC分类号： A61B1/3137 , A61B17/00234 , A61B17/00491 , A61B17/0643 , A61B17/11 , A61B17/12022 , A61B17/12045 , A61B17/12109 , A61B17/12131 , A61B17/12136 , A61B17/12159 , A61B17/12172 , A61B17/12186 , A61B17/1219 , A61B17/3417 , A61B17/3496 , A61B18/00 , A61B18/1445 , A61B18/1477 , A61B18/1492 , A61B18/24 , A61B90/361 , A61B90/40 , A61B2017/00243 , A61B2017/00247 , A61B2017/00252 , A61B2017/00504 , A61B2017/0641 , A61B2017/0647 , A61B2017/0649 , A61B2017/1107 , A61B2017/1139 , A61B2017/1205 , A61B2017/12127 , A61B2017/22038 , A61B2017/22077 , A61B2017/306 , A61B2017/347 , A61B2017/3488 , A61B2018/00392 , A61B2018/00404 , A61B2018/00869 , A61B2018/1425 , A61B2018/1475 , A61B2090/378 , A61B2090/3925 , A61B2090/3929 , A61B2090/3958 , A61F2/07 , A61F2/2493 , A61F2/90 , A61F2/95 , A61F2002/075 , A61F2002/30079 , A61F2002/8486 , A61F2210/009 , A61M2025/0076 , A61M2025/0096 , A61M2025/1052
摘要： Methods and apparatus for occluding blood flow within a blood vessel. In a first series of embodiments, the present invention comprises a plurality of embolic devices deployable through the lumen of a conventional catheter such that when deployed, said embolic devices remain resident and occlude blood flow at a specific site within the lumen of the blood vessel. Such embolic devices comprise either mechanical embolic devices that become embedded within or compress against the lumen of the vessel or chemical vaso-occlusive agents that seal off blood flow at a given site. A second embodiment of the present invention comprises utilization of a vacuum/cauterizing device capable of sucking in the lumen of the vessel about the device to maintain the vessel in a closed condition where there is then applied a sufficient amount of energy to cause the tissue collapsed about the device to denature into a closure. In a third series of embodiments, the present invention comprises the combination of an embolization facilitator coupled with the application of an energy force to form an intraluminal closure at a specified site within a vessel.
摘要翻译：阻塞血管内血流的方法和装置。在第一系列实施例中，本发明包括可以通过常规导管的内腔部署的多个栓塞装置，使得当展开时，所述栓塞装置保持驻留并阻塞在血管腔内的特定部位处的血流。这种栓塞装置包括机械栓塞装置，其嵌入或压缩容器的内腔或封闭给定部位的血流的化学血管闭塞剂。本发明的第二个实施方案包括使用能够吸收容器内腔的设备的真空/烧灼装置，以将容器保持在闭合状态，在那里然后施加足够量的能量以使组织折叠关于器件变性成闭合。在第三系列实施方案中，本发明包括栓塞促进剂与施加能量力的组合，以在血管内的指定部位形成腔内闭合。

5. 发明授权

US07771412B2 Environmental seal for fluid delivery device 有权
标题翻译：流体输送装置的环境密封
公开(公告)号：US07771412B2
公开(公告)日：2010-08-10
申请号：US11874776
申请日：2007-10-18
申请人： Marc Anderson , John Garibotto , Steven Dilanni
发明人： Marc Anderson , John Garibotto , Steven Dilanni
IPC分类号： A61M25/16
CPC分类号： F16L5/10 , A61M39/04 , A61M39/06 , A61M39/20 , A61M2039/066
摘要： An environmental seal for a fluid delivery device may include a 2-shot molded cap including a carrier and a low durometer silicone plug. The seal also may include a cap receptacle that applies compressive force to the plug displacing the plug material and forming a seal between the cap, the plug and the cap receptacle. A cannula may be slidably received in the plug and may move freely through the plug without compromising the seal.
摘要翻译：用于流体输送装置的环境密封件可以包括包括载体和低硬度硅胶塞的2-shot模制帽。密封件还可以包括盖插座，其向插头施加压力以移动塞子材料并且在盖，插头和盖插座之间形成密封。插管可以可滑动地容纳在插头中并且可以自由地移动穿过插头而不损害密封。

6. 发明申请

US20060178633A1 CHASSIS FOR FLUID DELIVERY DEVICE 审中-公开
标题翻译：流体输送装置用底盘
公开(公告)号：US20060178633A1
公开(公告)日：2006-08-10
申请号：US10907286
申请日：2005-03-28
申请人： John Garibotto , Steven DiIanni , David Zeller , Brian James , Marc Anderson , Fred Finnemore , David Clare , Jason Daigle
发明人： John Garibotto , Steven DiIanni , David Zeller , Brian James , Marc Anderson , Fred Finnemore , David Clare , Jason Daigle
IPC分类号： A61M37/00
CPC分类号： A61M5/1413 , A61M5/14244 , A61M5/1452 , A61M2205/0266
摘要： A chassis for a fluid delivery device provides mechanical and/or electrical connections between components of the fluid delivery device. The chassis includes a framework of structural members that mechanically interface components, such as a batteries, electrical contacts, fluid reservoirs, tubing, drive wheels, pivoting actuator components, sensors, control circuitry, alarms or indicators, sliding assemblies, springs, cams and latching members. The chassis may also include one or more electrically conductive paths along selected portions of the framework to provide electrical connections between the components.
摘要翻译：用于流体输送装置的底盘在流体输送装置的部件之间提供机械和/或电连接。底盘包括机械接口组件的结构构件的框架，例如电池，电触点，流体储存器，管道，驱动轮，枢转致动器部件，传感器，控制电路，报警器或指示器，滑动组件，弹簧，凸轮和闩锁会员底架还可以包括沿着框架的选定部分的一个或多个导电路径，以提供部件之间的电连接。

7. 发明授权

US06379319B1 Systems and methods for directing and snaring guidewires 有权
标题翻译：引导线和引导线的系统和方法
公开(公告)号：US06379319B1
公开(公告)日：2002-04-30
申请号：US09179737
申请日：1998-10-27
申请人： John Garibotto , Steven W. Kim , Jason Whitt , J. Christopher Flaherty , Joshua Makower , Motoya Hayase , John Chang
发明人： John Garibotto , Steven W. Kim , Jason Whitt , J. Christopher Flaherty , Joshua Makower , Motoya Hayase , John Chang
IPC分类号： A61B500
CPC分类号： A61B17/11 , A61B17/00491 , A61B17/0643 , A61B17/12022 , A61B17/12109 , A61B17/12136 , A61B17/221 , A61B17/32056 , A61B17/3417 , A61B18/00 , A61B18/1492 , A61B90/39 , A61B90/40 , A61B2017/00243 , A61B2017/00247 , A61B2017/00252 , A61B2017/00504 , A61B2017/1107 , A61B2017/1139 , A61B2017/22035 , A61B2017/22094 , A61B2017/2212 , A61B2017/306 , A61B2017/347 , A61B2018/00392 , A61F2/064 , A61F2/07 , A61F2/90 , A61F2002/061 , A61F2002/30079 , A61F2002/825 , A61F2210/009 , A61M25/0105 , A61M25/0133 , A61M2025/0076 , A61M2025/0161 , A61M2025/1052
摘要： Devices and methods for achieving directed placement of guidewires or other flexible rails over which other catheters or other devices may be introduced to a targeted location. A guidewire directing device includes a lumen extending between a proximal end and a distal peripheral opening for directing a guidewire laterally from the device, and may have a deflecting member with a predetermined deflection angle in the lumen adjacent the peripheral opening. A snaring device is also provided that includes one or more lumens through which a snare or other grasping member is directed for releasably capturing or coupling to a guidewire. The snaring and target guidewire devices may include cooperating end effectors for releasably coupling or securing the devices together. The devices may be used for directing, snaring and/or manipulating one or more guidewires between two blood vessels connected by an interstitial channel, for example, to “floss” a guidewire through the coronary arterial and venous systems between two percutaneous entry sites and/or to bypass a lesion in a vessel using proximal and distal interstitial channels communicating with an adjacent vessel.
摘要翻译：用于实现导线或其它柔性导轨的定向放置的装置和方法，其它导管或其它装置可以通过其引导到目标位置。导丝引导装置包括在近端和远侧外围开口之间延伸的腔，用于将导丝从装置横向引导，并且可具有在邻近周边开口的内腔中具有预定偏转角的偏转构件。还提供了一种包围一个或多个腔的扼流装置，一个圈套或其他把持件被引导通过该腔，用于可释放地捕获或连接到导丝。牵引和目标导丝装置可以包括用于可释放地将装置连接或固定在一起的协作的端部执行器。这些装置可用于引导，扼制和/或操纵通过间质通道连接的两个血管之间的一个或多个导线，例如通过两个经皮进入部位之间的冠状动脉和静脉系统“引导”导丝，和/ 或绕过与相邻血管连通的近端和远端间隙通道的血管中的病变。

8. 发明申请

US20080045996A1 Methods and Apparatus for Blocking Flow Through Blood Vessel 有权
标题翻译：阻塞流经血管的方法和装置
公开(公告)号：US20080045996A1
公开(公告)日：2008-02-21
申请号：US11924758
申请日：2007-10-26
申请人： Joshua Makower , J. Christopher Flaherty , Timothy Machold , Jason Whitt , Philip Evard , Patrick Macaulay , John Garibotto , Marc Jensen
发明人： Joshua Makower , J. Christopher Flaherty , Timothy Machold , Jason Whitt , Philip Evard , Patrick Macaulay , John Garibotto , Marc Jensen
IPC分类号： A61M29/02
CPC分类号： A61B1/3137 , A61B17/00234 , A61B17/00491 , A61B17/0643 , A61B17/11 , A61B17/12022 , A61B17/12045 , A61B17/12109 , A61B17/12131 , A61B17/12136 , A61B17/12159 , A61B17/12172 , A61B17/12186 , A61B17/1219 , A61B17/3417 , A61B17/3496 , A61B18/00 , A61B18/1445 , A61B18/1477 , A61B18/1492 , A61B18/24 , A61B90/361 , A61B90/40 , A61B2017/00243 , A61B2017/00247 , A61B2017/00252 , A61B2017/00504 , A61B2017/0641 , A61B2017/0647 , A61B2017/0649 , A61B2017/1107 , A61B2017/1139 , A61B2017/1205 , A61B2017/12127 , A61B2017/22038 , A61B2017/22077 , A61B2017/306 , A61B2017/347 , A61B2017/3488 , A61B2018/00392 , A61B2018/00404 , A61B2018/00869 , A61B2018/1425 , A61B2018/1475 , A61B2090/378 , A61B2090/3925 , A61B2090/3929 , A61B2090/3958 , A61F2/07 , A61F2/2493 , A61F2/90 , A61F2/95 , A61F2002/075 , A61F2002/30079 , A61F2002/8486 , A61F2210/009 , A61M2025/0076 , A61M2025/0096 , A61M2025/1052
摘要： Methods and apparatus for occluding blood flow within a blood vessel. In a first series of embodiments, the present invention comprises a plurality of embolic devices deployable through the lumen of a conventional catheter such that when deployed, said embolic devices remain resident and occlude blood flow at a specific site within the lumen of the blood vessel. Such embolic devices comprise either mechanical embolic devices that become embedded within or compress against the lumen of the vessel or chemical vaso-occlusive agents that seal off blood flow at a given site. A second embodiment of the present invention comprises utilization of a vacuum/cauterizing device capable of sucking in the lumen of the vessel about the device to maintain the vessel in a closed condition where there is then applied a sufficient amount of energy to cause the tissue collapsed about the device to denature into a closure. In a third series of embodiments, the present invention comprises the combination of an embolization facilitator coupled with the application of an energy force to form an intraluminal closure at a specified site within a vessel.
摘要翻译：阻塞血管内血流的方法和装置。在第一系列实施例中，本发明包括可以通过常规导管的内腔部署的多个栓塞装置，使得当展开时，所述栓塞装置保持驻留并且阻塞在血管腔内的特定位置处的血流。这种栓塞装置包括机械栓塞装置，其嵌入或压缩容器的内腔或封闭给定部位的血流的化学血管闭塞剂。本发明的第二个实施方案包括使用能够吸收容器内腔的设备的真空/烧灼装置，以将容器保持在闭合状态，在那里然后施加足够量的能量以使组织折叠关于器件变性成闭合。在第三系列实施方案中，本发明包括栓塞促进剂与施加能量力的组合，以在血管内的指定部位形成腔内闭合。

9. 发明授权

US07316655B2 Systems and methods for directing and snaring guidewires 有权
标题翻译：引导线和引导线的系统和方法
公开(公告)号：US07316655B2
公开(公告)日：2008-01-08
申请号：US10136929
申请日：2002-04-30
申请人： John Garibotto , Steven W. Kim , Jason Whitt , J. Christopher Flaherty , Joshua Makower , Motoya Hayase , John Chang
发明人： John Garibotto , Steven W. Kim , Jason Whitt , J. Christopher Flaherty , Joshua Makower , Motoya Hayase , John Chang
IPC分类号： A61B5/00 , A61M25/00
CPC分类号： A61B17/11 , A61B17/00491 , A61B17/0643 , A61B17/12022 , A61B17/12109 , A61B17/12136 , A61B17/221 , A61B17/32056 , A61B17/3417 , A61B18/00 , A61B18/1492 , A61B90/39 , A61B90/40 , A61B2017/00243 , A61B2017/00247 , A61B2017/00252 , A61B2017/00504 , A61B2017/1107 , A61B2017/1139 , A61B2017/22035 , A61B2017/22094 , A61B2017/2212 , A61B2017/306 , A61B2017/347 , A61B2018/00392 , A61F2/064 , A61F2/07 , A61F2/90 , A61F2002/061 , A61F2002/30079 , A61F2002/825 , A61F2210/009 , A61M25/0105 , A61M25/0133 , A61M2025/0076 , A61M2025/0161 , A61M2025/1052
摘要： Devices and methods for achieving directed placement of guidewires or other flexible rails over which other catheters or other devices may be introduced to a targeted location. A guidewire directing device includes a lumen extending between a proximal end and a distal peripheral opening for directing a guidewire laterally from the device, and may have a deflecting member with a predetermined deflection angle in the lumen adjacent the peripheral opening. A snaring device is also provided that includes one or more lumens through which a snare or other grasping member is directed for releasably capturing or coupling to a guidewire. The snaring and target guidewire devices may include cooperating end effectors for releasably coupling or securing the devices together. The devices may be used for directing, snaring and/or manipulating one or more guidewires between two blood vessels connected by an interstitial channel, for example, to “floss” a guidewire through the coronary arterial and venous systems between two percutaneous entry sites and/or to bypass a lesion in a vessel using proximal and distal interstitial channels communicating with an adjacent vessel.
摘要翻译：用于实现导线或其它柔性导轨的定向放置的装置和方法，其它导管或其它装置可以通过其引导到目标位置。导丝引导装置包括在近端和远侧外围开口之间延伸的腔，用于将导丝从装置横向引导，并且可具有在邻近周边开口的内腔中具有预定偏转角的偏转构件。还提供了一种包围一个或多个腔的扼流装置，一个圈套或其他把持件被引导通过该腔，用于可释放地捕获或连接到导丝。牵引和目标导丝装置可以包括用于可释放地将装置连接或固定在一起的协作的端部执行器。这些装置可用于引导，扼制和/或操纵通过间质通道连接的两个血管之间的一个或多个导线，例如通过两个经皮进入部位之间的冠状动脉和静脉系统“引导”导丝，和/ 或绕过与相邻血管连通的近端和远端间隙通道的血管中的病变。

10. 发明授权

US06960192B1 Transcutaneous fluid delivery system 失效
标题翻译：经皮输液系统
公开(公告)号：US06960192B1
公开(公告)日：2005-11-01
申请号：US10128206
申请日：2002-04-23
申请人： J. Christopher Flaherty , William Gorman , John Garibotto , Timothy Wood , Patick Gutelius
发明人： J. Christopher Flaherty , William Gorman , John Garibotto , Timothy Wood , Patick Gutelius
IPC分类号： A61M5/20 , A61M20060101 , A61M5/00 , A61M5/142 , A61M5/178 , A61M5/31 , A61M37/00
CPC分类号： A61M5/14248 , A61M2005/14252 , A61M2005/1426 , A61M2205/0266 , A61M2205/3592
摘要： A device for delivering fluid to a person includes a reservoir for containing a fluid to be delivered to the person; a fluid transport device for dispensing fluid from the reservoir to the person, the fluid transport device including a proximal end in fluid communication with the reservoir and a distal end having a penetrating member for piercing the skin of the person to facilitate the delivery of fluid to the person through the fluid transport device; a housing containing the reservoir and the fluid transport device, the housing including an exit port for receiving the distal end of the fluid transport device upon injection of the distal end into the person and means for securing a first wall of the housing to the skin of the person; and an injection activation device including a driving mechanism contacting the fluid transport device for driving the penetrating member from a first position within the housing, through the exit port to a second position, external to the housing and into the skin of the person.
摘要翻译：用于将流体输送给人的装置包括用于容纳待传送给人的流体的储存器; 用于将流体从储存器分配给人的流体输送装置，所述流体输送装置包括与储存器流体连通的近端和具有穿透构件的远端，所述穿透构件用于刺穿人的皮肤以便于将流体输送到该人通过流体输送装置; 容纳所述储存器和所述流体输送装置的壳体，所述壳体包括用于在将所述远端注射到所述人体中时接收所述流体输送装置的远端的出口，以及用于将所述壳体的第一壁固定到所述壳体的皮肤的装置此人; 以及注射激活装置，其包括与所述流体输送装置接触的驱动机构，用于将所述穿透构件从所述壳体内的第一位置驱动，通过所述出口到达所述壳体外部并进入所述人的皮肤的第二位置。

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