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    • 4. 发明申请
    • IMAGING BREAST CANCEROUS LESIONS WITH MICROCALCIFICATIONS
    • 成像乳腺癌与微血管切除术
    • US20110182402A1
    • 2011-07-28
    • US12695896
    • 2010-01-28
    • Larry D. Partain
    • Larry D. Partain
    • H05G1/60H05G1/02A61B6/04
    • A61B6/502A61B6/032A61B6/0435A61B6/4014A61B6/4441A61B6/587A61B6/589
    • A radiation system includes a first radiation source and a first detector positioned opposite to each other configured to image a body portion, and a second radiation source and a second detector positioned opposite to each other configured to image a region of interest in the body portion. The first radiation source has a first spot size and the first detector has a first pixel size. The second radiation source has a second spot size and the second detector has a second pixel size. The first spot size of the first radiation source may be different from the second spot size of the second radiation source, and/or the first pixel size of the first detector may be different from the second pixel size of the second detector.
    • 辐射系统包括第一辐射源和被配置为对身体部分进行成像的彼此相对定位的第一检测器,以及被配置为对身体部分中的感兴趣区域成像的第二辐射源和彼此相对定位的第二检测器。 第一辐射源具有第一光斑尺寸,并且第一检测器具有第一像素尺寸。 第二辐射源具有第二光斑尺寸,第二检测器具有第二像素尺寸。 第一辐射源的第一光斑尺寸可以不同于第二辐射源的第二光斑尺寸,和/或第一检测器的第一像素尺寸可以不同于第二检测器的第二像素尺寸。
    • 8. 发明申请
    • Method of Determining the Probabilities of Suspect Nodules Being Malignant
    • 确定可疑结节恶性概率的方法
    • US20140369582A1
    • 2014-12-18
    • US13918981
    • 2013-06-16
    • Larry D. PARTAIN
    • Larry D. PARTAIN
    • G06T7/00
    • G06T7/0014G06T2207/10081G06T2207/20076G06T2207/30064
    • Methods of determining a probability of a suspect cancer nodule being malignant are provided. In one embodiment, the method begins with tabulating histogram data of malignant and benign nodules as a function of biomarker values for a specified patient population suspect of having a specific type of cancer. Next, the tabulated histogram data is separated into a plurality of biomarker bins where the bins are ranges of biomarker values, and malignancy probability fractions are calculated for each biomarker bin by dividing a number of true positives in each marker bin by a summed total of all true and false positives in each bin. Finally, a suspect nodule in a patient is scanned, a biomarker value for the suspect nodule determined, and a malignancy probability for the suspect nodule determined by reference to the tabulated histogram data and the malignancy probability fractions. Other embodiments are also disclosed.
    • 提供了确定可疑癌症结节恶性概率的方法。 在一个实施方案中,该方法开始列出恶性和良性结节的直方图数据,作为具有特定类型癌症的特定患者群体的生物标志物值的函数。 接下来,列表的直方图数据被分成多个生物标志物箱,其中箱是生物标记值的范围,并且通过将每个标记箱中的真阳性数除以总和的总数,计算每个生物标记箱的恶性概率分数 每个垃圾箱中的真假。 最后,扫描患者中的疑似结节,确定疑似结节的生物标记值,并通过参考列表直方图数据和恶性概率分数确定疑似结节的恶性概率。 还公开了其他实施例。