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1. 发明申请

US20110105356A1 COMPOSITIONS AND METHODS FOR PROVIDING SUBSTANCES TO AND FROM AN ARRAY 审中-公开
标题翻译：用于向物质提供物质和从阵列提供物质的组合物和方法
公开(公告)号：US20110105356A1
公开(公告)日：2011-05-05
申请号：US12991121
申请日：2009-05-05
申请人： Chad F. DeRosier , John A. Moon , Fiona E. Black , Robert Yang , Hongji Ren , David L. Heiner
发明人： Chad F. DeRosier , John A. Moon , Fiona E. Black , Robert Yang , Hongji Ren , David L. Heiner
IPC分类号： C40B30/04 , C40B50/00 , C40B50/06 , C40B40/00
CPC分类号： C40B50/14 , B01J19/0046 , B01J2219/00317 , B01J2219/00382 , B01J2219/00495 , B01J2219/00527 , B01J2219/00585 , B01J2219/00596 , B01J2219/00605 , B01J2219/00644 , B01J2219/00722 , B01J2219/00725 , B01L3/5085 , B01L2300/0819 , C40B60/14
摘要： Methods, kits, systems, and multilayer transfer media for transferring a substance to and from an array are disclosed herein. Also disclosed herein are methods of detecting a substance that has been transferred to an array.
摘要翻译：本文公开了用于将物质转移到阵列和从阵列转移物质的方法，试剂盒，系统和多层转移介质。本文还公开了检测已经转移到阵列的物质的方法。

2. 发明授权

US09073033B2 Methods and compositions for processing chemical reactions 有权
标题翻译：用于处理化学反应的方法和组合物
公开(公告)号：US09073033B2
公开(公告)日：2015-07-07
申请号：US13008317
申请日：2011-01-18
申请人： Michal Lebl , Michel Perbost , Chad F. DeRosier , Mark J. Nibbe , Steve R. Burgett , David L. Heiner
发明人： Michal Lebl , Michel Perbost , Chad F. DeRosier , Mark J. Nibbe , Steve R. Burgett , David L. Heiner
IPC分类号： B01L3/00 , B01J19/22 , B01J14/00 , B01J19/00 , B01L7/00
CPC分类号： B01J19/22 , B01J14/005 , B01J19/0046 , B01J2219/00306 , B01J2219/00324 , B01J2219/00351 , B01J2219/0036 , B01J2219/00378 , B01J2219/0038 , B01J2219/00495 , B01J2219/00518 , B01J2219/00533 , B01J2219/00585 , B01J2219/00596 , B01J2219/00644 , B01J2219/00686 , B01J2219/00693 , B01J2219/00722 , B01L3/50851 , B01L7/5255 , B01L2300/069 , B01L2300/0812 , B01L2300/0829 , B01L2300/123
摘要： Disclosed herein are compositions, methods and systems for the processing of chemical reactions, such as the synthesis of polymers.
摘要翻译：本文公开了用于处理化学反应的组合物，方法和系统，例如聚合物的合成。

3. 发明申请

US20110178285A1 METHODS AND COMPOSITIONS FOR PROCESSING CHEMICAL REACTIONS 有权
标题翻译：用于加工化学反应的方法和组合物
公开(公告)号：US20110178285A1
公开(公告)日：2011-07-21
申请号：US13008317
申请日：2011-01-18
申请人： Michal Lebl , Michel Perbost , Chad F. DeRosier , Mark J. Nibbe , Steve R. Burgett , David L. Heiner
发明人： Michal Lebl , Michel Perbost , Chad F. DeRosier , Mark J. Nibbe , Steve R. Burgett , David L. Heiner
IPC分类号： C07H21/00 , B01J7/02 , B05D5/00
CPC分类号： B01J19/22 , B01J14/005 , B01J19/0046 , B01J2219/00306 , B01J2219/00324 , B01J2219/00351 , B01J2219/0036 , B01J2219/00378 , B01J2219/0038 , B01J2219/00495 , B01J2219/00518 , B01J2219/00533 , B01J2219/00585 , B01J2219/00596 , B01J2219/00644 , B01J2219/00686 , B01J2219/00693 , B01J2219/00722 , B01L3/50851 , B01L7/5255 , B01L2300/069 , B01L2300/0812 , B01L2300/0829 , B01L2300/123
摘要： Disclosed herein are compositions, methods and systems for the processing of chemical reactions, such as the synthesis of polymers.
摘要翻译：本文公开了用于处理化学反应的组合物，方法和系统，例如聚合物的合成。

4. 发明申请

US20110269641A1 METHODS AND SYSTEMS FOR CONTROLLING LIQUIDS IN MULTIPLEX ASSAYS 有权
标题翻译：用于控制多重测定中液体的方法和系统
公开(公告)号：US20110269641A1
公开(公告)日：2011-11-03
申请号：US13143027
申请日：2010-02-23
申请人： Chad F. DeRosier
发明人： Chad F. DeRosier
IPC分类号： C40B30/04 , C40B60/00 , C40B40/00
CPC分类号： G01N1/20 , G01N35/028 , Y10T436/2575
摘要： Methods and systems for venting a well that receives a liquid. The method includes providing a microplate including a well that has a cavity with an open inlet and a closed end. The cavity extends between the open inlet and the closed end. The cavity is defined by a wall surface having a cross-sectional contour that includes at least one continuous section and at least one discontinuity section. The method also includes depositing a liquid into the open inlet of the well. The liquid enters the cavity and flows toward the closed end to at least partially fill the well. The liquid flows along the continuous section of the wall surface and remains separated from the discontinuity section of the wall surface, thereby maintaining a gas exhaust path along a spacing between the liquid and the discontinuity section as the liquid flows toward the closed end.
摘要翻译：用于排放接收液体的井的方法和系统。该方法包括提供微孔板，其包括具有开口和闭合端的空腔的微孔板。空腔在开口和封闭端之间延伸。空腔由具有包括至少一个连续部分和至少一个不连续部分的横截面轮廓的壁表面限定。该方法还包括将液体沉积到井的开放入口中。液体进入空腔并朝向封闭端流动，至少部分填充井。液体沿着壁表面的连续部分流动并且保持与壁表面的不连续部分分离，从而当液体朝向封闭端流动时，沿着液体和不连续部分之间的间隔保持气体排出路径。

5. 发明授权

US08338187B2 Methods and systems for controlling liquids in multiplex assays 有权
标题翻译：在多重测定中控制液体的方法和系统
公开(公告)号：US08338187B2
公开(公告)日：2012-12-25
申请号：US13143027
申请日：2010-02-23
申请人： Chad F. DeRosier
发明人： Chad F. DeRosier
IPC分类号： G01N1/10 , B01L3/00
CPC分类号： G01N1/20 , G01N35/028 , Y10T436/2575
摘要： Methods and systems for venting a well that receives a liquid. The method includes providing a microplate including a well that has a cavity with an open inlet and a closed end. The cavity extends between the open inlet and the closed end. The cavity is defined by a wall surface having a cross-sectional contour that includes at least one continuous section and at least one discontinuity section. The method also includes depositing a liquid into the open inlet of the well. The liquid enters the cavity and flows toward the closed end to at least partially fill the well. The liquid flows along the continuous section of the wall surface and remains separated from the discontinuity section of the wall surface, thereby maintaining a gas exhaust path along a spacing between the liquid and the discontinuity section as the liquid flows toward the closed end.
摘要翻译：用于排放接收液体的井的方法和系统。该方法包括提供微孔板，其包括具有开口和闭合端的空腔的微孔板。空腔在开口和封闭端之间延伸。空腔由具有包括至少一个连续部分和至少一个不连续部分的横截面轮廓的壁表面限定。该方法还包括将液体沉积到井的开放入口中。液体进入空腔并朝向封闭端流动，至少部分填充井。液体沿着壁表面的连续部分流动并且保持与壁表面的不连续部分分离，从而当液体朝向封闭端流动时，沿着液体和不连续部分之间的间隔保持气体排出路径。

6. 发明授权

US08765486B2 Methods and systems for controlling liquids in multiplex assays 有权
标题翻译：在多重测定中控制液体的方法和系统
公开(公告)号：US08765486B2
公开(公告)日：2014-07-01
申请号：US13681689
申请日：2012-11-20
申请人： Chad F. DeRosier
发明人： Chad F. DeRosier
IPC分类号： G01N1/10 , B01L3/00
CPC分类号： G01N1/20 , G01N35/028 , Y10T436/2575
摘要： A fluidic device for conveying liquid to a well of a microplate. The device includes a support structure configured to be mounted along the microplate. The device also includes a microfluidic tube coupled to the support structure. The tube has an inlet, an outlet, and an open-sided channel that extends longitudinally therebetween. The tube has a cross-section that includes an interior contour with a gap therein. The gap extends at least partially along a length of the tube. The tube is configured to convey liquid to the well of the microplate when the tube is held in a dispensing orientation.
摘要翻译：用于将液体输送到微板的孔的流体装置。该装置包括构造成沿微孔板安装的支撑结构。该装置还包括耦合到支撑结构的微流体管。管具有入口，出口和在其之间纵向延伸的开放侧通道。该管具有包括其中具有间隙的内部轮廓的横截面。间隙至少部分地沿着管的长度延伸。管被配置成当管保持在分配取向时将液体输送到微板的孔。

7. 发明申请

US20130079252A1 METHODS AND SYSTEMS FOR CONTROLLING LIQUIDS IN MULTIPLEX ASSAYS 有权
标题翻译：用于控制多重测定中液体的方法和系统
公开(公告)号：US20130079252A1
公开(公告)日：2013-03-28
申请号：US13681689
申请日：2012-11-20
申请人： Chad F. DeRosier
发明人： Chad F. DeRosier
IPC分类号： G01N1/20
CPC分类号： G01N1/20 , G01N35/028 , Y10T436/2575
摘要： A fluidic device for conveying liquid to a well of a microplate. The device includes a support structure configured to be mounted along the microplate. The device also includes a microfluidic tube coupled to the support structure. The tube has an inlet, an outlet, and an open-sided channel that extends longitudinally therebetween. The tube has a cross-section that includes an interior contour with a gap therein. The gap extends at least partially along a length of the tube. The tube is configured to convey liquid to the well of the microplate when the tube is held in a dispensing orientation.
摘要翻译：用于将液体输送到微板的孔的流体装置。该装置包括构造成沿微孔板安装的支撑结构。该装置还包括耦合到支撑结构的微流体管。管具有入口，出口和在其之间纵向延伸的开放侧通道。该管具有包括其中具有间隙的内部轮廓的横截面。间隙至少部分地沿着管的长度延伸。管被配置成当管保持在分配取向时将液体输送到微板的孔。

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