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1. 发明授权

US10414774B2 Compound useful for altering the levels of bile acids for the treatment of diabetes and cardiometabolc disease 有权
公开(公告)号：US10414774B2
公开(公告)日：2019-09-17
申请号：US16324596
申请日：2017-08-10
申请人： Merck Sharp & Dohme Corp. , Jared N. Cumming , Kevin D. Dykstra , Alan Hruza , Derun Li , Hong Liu , Haiqun Tang , Brandon M. Taoka , Andreas Verras , Shawn P. Walsh , Wen-Lian Wu
发明人： Jared N. Cumming , Kevin D. Dykstra , Alan Hruza , Derun Li , Hong Liu , Haiqun Tang , Brandon M. Taoka , Andreas Verras , Shawn P. Walsh , Wen-Lian Wu
IPC分类号： C07D487/04 , C07D519/00 , A61P3/10 , C07D498/04 , C07D513/04 , C07D471/04
摘要： Described herein are compounds of Formula (I) or a pharmaceutically acceptable salt thereof. The compounds of Formula I act as Cyp8b1 inhibitors and can be useful in preventing, treating or acting as a remedial agent for diabetes and cardiovascular disease.

2. 发明授权

US10039855B2 Elastic fiber containing an anti-tack additive 有权
公开(公告)号：US10039855B2
公开(公告)日：2018-08-07
申请号：US12969725
申请日：2010-12-16
申请人： James Michael Lambert , Young D. Nguyen , Robert O. Waldbauer, Jr. , Hong Liu
发明人： James Michael Lambert , Young D. Nguyen , Robert O. Waldbauer, Jr. , Hong Liu
IPC分类号： D01F1/10 , A61L15/14 , A61L15/24 , C08L23/14 , D01F6/30 , D01F6/46 , C08K5/09 , C08K5/20 , C08L9/00
摘要： Embodiments of the disclosure include elastomeric stretch fibers containing an anti-tack agent, methods of preparing the fiber, methods of using this fiber, articles including this fiber, and the like.

3. 发明申请

US20170323121A1 STORAGE DEVICE TAMPERING DETECTION 有权
公开(公告)号：US20170323121A1
公开(公告)日：2017-11-09
申请号：US14900962
申请日：2014-05-15
申请人： Hong LIU , Abhay KATARIA , Chao CHEN , WeiWei FENG , Monty FOREHAND , William Erik ANDERSON , SEAGATE TECHNOLOGY LLC
发明人： Hong LIU , Abhay KATARIA , Chao CHEN , WeiWei FENG , Monty A. FOREHAND , William Erik ANDERSON
IPC分类号： G06F21/73 , G06F21/80 , G06F21/79 , G06F21/86 , G06F21/57
CPC分类号： G06F21/73 , G06F21/57 , G06F21/78 , G06F21/79 , G06F21/80 , G06F21/86
摘要： Apparatus (400, 500) and method (200, 220, 240, 260, 280, 300) for detecting unauthorized tampering with a data storage device (100, 110, 140, 520). In some embodiments, the data storage device has a housing (112, 142) and a memory (192) supported by the housing. A first identifier value (202A, 222A, 242A, 262A, 282A, 306A) is stored on an external surface of the housing and a second identifier value (202B, 222B, 242B, 262B, 282B, 306B) is stored within the memory. A digital signature (210, 256, 296) generated in response to the first and second identifier values and in response to a private key (208, 254, 288) is stored on the storage device. Thereafter, the first identifier value is retrieved from the external surface of the housing and the second identifier value is retrieved from the memory. The storage device is authenticated using the retrieved first and second identifier values, the digital signature and a public key (228, 274, 312).

4. 发明授权

US09573939B2 Substituted benzofuran compounds and methods of use thereof for the treatment of viral diseases 有权
标题翻译：取代的苯并呋喃化合物及其用于治疗病毒性疾病的方法
公开(公告)号：US09573939B2
公开(公告)日：2017-02-21
申请号：US14343462
申请日：2012-08-16
申请人： Casey C. McComas , Nigel J. Liverton , Joerg Habermann , Uwe Koch , Frank Narjes , Peng Li , Xuanjia Peng , Richard Soll , Hao Wu , Anandan Palani , Xing Dai , Hong Liu , Shuwen He , Qun Dang
发明人： Casey C. McComas , Nigel J. Liverton , Joerg Habermann , Uwe Koch , Frank Narjes , Peng Li , Xuanjia Peng , Richard Soll , Hao Wu , Anandan Palani , Xing Dai , Hong Liu , Shuwen He , Qun Dang
IPC分类号： C07D405/04 , C07D405/14 , C07D487/04 , C07D471/04 , C07D473/00 , C07D498/04 , A61K45/06 , A61K31/416 , A61K31/52 , A61K31/437 , A61K31/4045 , A61K31/4184 , A61K31/4375 , A61K31/4439 , A61K31/4985 , A61K31/5025
CPC分类号： C07D405/04 , A61K31/4045 , A61K31/416 , A61K31/4184 , A61K31/437 , A61K31/4375 , A61K31/4439 , A61K31/4985 , A61K31/5025 , A61K31/52 , A61K45/06 , C07D405/14 , C07D471/04 , C07D473/00 , C07D487/04 , C07D498/04 , Y02A50/387 , Y02A50/389 , Y02A50/395 , A61K2300/00
摘要： The present invention relates to compounds of formula (I) that are useful as hepatitis C virus (HCV) NS5B polymerase inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5B polymerase activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and/or viral production in a cell-based system.
摘要翻译：本发明涉及可用作丙型肝炎病毒（HCV）NS5B聚合酶抑制剂，这种化合物的合成以及这些化合物用于抑制HCV NS5B聚合酶活性用于治疗或预防HCV感染的式（I）化合物并用于在基于细胞的系统中抑制HCV病毒复制和/或病毒生产。

5. 发明授权

US09541453B2 Infrared detector 有权
标题翻译：红外探测器
公开(公告)号：US09541453B2
公开(公告)日：2017-01-10
申请号：US12876352
申请日：2010-09-07
申请人： Chun-Hua Hu , Chang-Hong Liu , Shou-Shan Fan
发明人： Chun-Hua Hu , Chang-Hong Liu , Shou-Shan Fan
IPC分类号： G01J5/16 , G01J5/12 , G01J5/14 , G01J5/04 , B82Y30/00 , H01L51/00 , H01L51/44 , H01L31/0256 , G01J5/02 , H01L35/32 , G01J5/06 , G01J1/16
CPC分类号： G01J5/16 , B82Y30/00 , G01J1/1626 , G01J5/02 , G01J5/023 , G01J5/04 , G01J5/048 , G01J5/12 , G01J5/14 , G01J2005/065 , G01J2005/068 , G01N2201/022 , H01L35/32 , H01L51/0048 , H01L51/441 , H01L51/448 , H01L2031/0344
摘要： An infrared detector includes a detecting element, a first electrode, a second electrode, and a covering structure. The detecting element defines an absorbing part and a non-absorbing part. The detecting element includes a first end and a second end opposite with the first end. The first end is disposed in the absorbing part. The second end is disposed in the non-absorbing part. The first electrode is electrically connected with the first end. The second electrode is electrically connected with the second end. The covering structure covers the non-absorbing part. The detecting element further includes a carbon nanotube layer. The carbon nanotube layer includes a plurality of carbon nanotubes disposed uniformly.
摘要翻译：红外检测器包括检测元件，第一电极，第二电极和覆盖结构。检测元件限定吸收部分和非吸收部分。检测元件包括第一端和与第一端相对的第二端。第一端设置在吸收部中。第二端设置在非吸收部。第一电极与第一端电连接。第二电极与第二端电连接。覆盖结构覆盖非吸收部分。检测元件还包括碳纳米管层。碳纳米管层包括均匀排列的多个碳纳米管。

6. 发明申请

US20160262572A1 Insulating Pot Bottom For Stockpots 有权
标题翻译：绝缘罐底部为库存
公开(公告)号：US20160262572A1
公开(公告)日：2016-09-15
申请号：US15054202
申请日：2016-02-26
申请人： Chung-Yen Cheng , Chun-Hong Liu
发明人： Chung-Yen Cheng
IPC分类号： A47J41/00 , A47J36/34
CPC分类号： A47J41/0055 , A47J36/34
摘要： An insulating pot bottom for stockpots has a connecting base, a flame guiding block, and multiple insulating mounts. The connecting base has a bottom panel, an inlet hole, and multiple abutting ribs. The inlet hole is formed through the bottom panel. The abutting ribs are formed on and protrude from the bottom panel at spaced intervals around the inlet hole, and each one of the abutting ribs has at least one protrusion. The flame guiding block is mounted in the inlet hole of the connecting base and abuts the protrusions of the abutting ribs. The insulating mounts are mounted on the connecting base, and respectively abut the abutting ribs around the flame guiding block.
摘要翻译：储罐的绝缘罐底部具有连接底座，导火块和多个绝缘支架。连接底座具有底板，入口孔和多个邻接肋。入口孔通过底板形成。邻接肋形成在入口孔周围间隔开的底板上并从其突出，并且每个邻接肋具有至少一个突起。火焰引导块安装在连接基座的入口孔中并邻接抵接肋的突起。绝缘安装件安装在连接基座上，并且分别邻接在引导块周围的邻接肋。

7. 发明授权

US09441115B2 Aqueous phase pore sealing agent imroving PCB coating oxidation-resistant and corrosion-resistant properties and method for using same 有权
标题翻译：水相孔密封剂可以使PCB涂层具有抗氧化和耐腐蚀性能和使用方法
公开(公告)号：US09441115B2
公开(公告)日：2016-09-13
申请号：US14358026
申请日：2011-11-14
申请人： Xiaoming Wu , Yong Lu , Hong Liu , Yinfeng Wu , Qianyuan Liu
发明人： Xiaoming Wu , Yong Lu , Hong Liu , Yinfeng Wu , Qianyuan Liu
IPC分类号： C09D5/08 , C23C22/60 , C23C22/68 , H05K3/28
CPC分类号： C09D5/086 , C23C22/60 , C23C22/68 , H05K3/282 , H05K2203/0786 , H05K2203/0793
摘要： The present invention relates to a water-based pore sealing agent enhancing PCB coating anti-oxidation and anti-corrosion properties, consisting of, by weight, 4-12 parts of a corrosion inhibitor, 15-25 parts of a mixed surfactants system, 10-20 parts of an ion chelating agent, 6-15 parts of a pH regulator, 20-40 parts of a builder, and the rest being purified water. When used to perform pore sealing on a PCB, the water-based pore sealing agent is diluted with purified water first to be diluted 10-100 times, preferably, 100/8-100/3 times. The pH value is 7-11, and is preferably 7.5-9.5. The surface tension is 18-28 dyn/cm. The pore sealing treatment uses a immersion process, and preferably ultrasonic waves are added at the same time to assist in cleaning the pores. For the pore sealing treatment, the temperature is 20-60° C., and the time is 60-150 seconds. After pore sealing, the temperature for drying the coated piece is 80-150° C., and the time is 60-120 seconds. The PCB treated with the water-based pore sealing agent of the present invention undergoes the neutral salt spray test, the nitric acid vapor test, the mixed gas test, and the sulfur dioxide and bonding tensile strength test, and the results have indicated that the anti-oxidation and anti-corrosion properties of the coating thereof are significantly enhanced.
摘要翻译：本发明涉及一种提高PCB涂层抗氧化和抗腐蚀性能的水性密封剂，由重量比为4-12份的缓蚀剂组成，15-25份混合表面活性剂体系，10 -20份离子螯合剂，6-15份pH调节剂，20-40份助洗剂，其余为纯化水。当用于在PCB上进行孔密封时，首先用净化水稀释水基密封剂以稀释10-100倍，优选为100 / 8-100 / 3倍。 pH值为7-11，优选为7.5-9.5。表面张力为18-28dyn / cm。孔密封处理使用浸渍法，优选同时加入超声波以辅助清洁毛孔。对于孔密封处理，温度为20-60℃，时间为60-150秒。孔密封后，涂层的干燥温度为80-150℃，时间为60-120秒。用本发明的水性密封剂处理的PCB经过中性盐雾试验，硝酸蒸汽试验，混合气体试验，二氧化硫和接合拉伸强度试验，结果表明，其涂层的抗氧化和抗腐蚀性能显着提高。

8. 发明授权

US09265653B2 Thermal therapy device incorporating carbon nanotubes 有权
标题翻译：掺入碳纳米管的热疗装置
公开(公告)号：US09265653B2
公开(公告)日：2016-02-23
申请号：US13109200
申请日：2011-05-17
申请人： Lu-Zhuo Chen , Chang-Hong Liu , Shou-Shan Fan
发明人： Lu-Zhuo Chen , Chang-Hong Liu , Shou-Shan Fan
IPC分类号： A61F7/00 , B82Y30/00 , A61H7/00
CPC分类号： A61F7/007 , A61F2007/0071 , A61H7/007 , A61H2201/0207 , B82Y30/00
摘要： A thermal therapy device includes a substrate and at least one heating unit arranged on the substrate. The at least one heating unit includes a heating element, a first electrode, and a second electrode. The heating element includes a carbon nanotube film structure and a polymer matrix. The carbon nanotube film structure is substantially parallel to and offset from a central plane of the polymer matrix. The first electrode and the second electrode are electrically connected to the carbon nanotube film structure, and control the amount of heat and deformation produced by the carbon nanotube film structure.
摘要翻译：热疗装置包括基板和布置在基板上的至少一个加热单元。所述至少一个加热单元包括加热元件，第一电极和第二电极。加热元件包括碳纳米管膜结构和聚合物基体。碳纳米管膜结构基本上平行于聚合物基体的中心平面并偏离聚合物基体的中心平面。第一电极和第二电极与碳纳米管膜结构电连接，并且控制由碳纳米管膜结构产生的热量和变形量。

9. 发明授权

US09253981B2 Stable suspension concentrate formulation for water-soluble compounds 有权
标题翻译：用于水溶性化合物的稳定的悬浮浓缩物配方
公开(公告)号：US09253981B2
公开(公告)日：2016-02-09
申请号：US12445905
申请日：2007-10-16
申请人： Robin W. Dexter , Hong Liu
发明人： Robin W. Dexter , Hong Liu
IPC分类号： A01N43/40 , A01P7/04 , A61K47/02 , A61K47/38 , A01N51/00
CPC分类号： A01N43/50 , A01N25/02 , A01N43/40 , A01N51/00 , A61K47/02 , A61K47/38 , A61L2400/06 , A01N25/04 , A01N59/02 , A01N59/06 , A01N2300/00
摘要： The present invention is directed to an insecticidal water based suspension concentrate formulation comprising a water-soluble insecticide selected from the group consisting of N-cyanomethyl-4-(trifluoromethyl)nicotinamide and (EZ)-1-(6-chloro-3-pyridylmethyl)-N-nitroimidazolidin-2-ylidineamine and at least one water-soluble salt selected from the group consisting of magnesium sulfate (hydrated and anhydrous forms) and sodium sulfate, wherein the water-soluble insecticide is present in an insecticidally effective amount and methods of use.
摘要翻译：本发明涉及一种杀虫水基悬浮液浓缩物制剂，其包含选自N-氰基甲基-4-（三氟甲基）烟酰胺和（EZ）-1-（6-氯-3-吡啶基甲基）-N-硝基咪唑烷-2-基胺和至少一种选自硫酸镁（水合和无水形式）和硫酸钠的水溶性盐，其中水溶性杀虫剂以杀虫有效量存在，并且方法的使用。

10. 发明授权

US09225454B1 Aggregation and de-agreggation of bandwidth within data centers using passive optical elements 有权
标题翻译：使用无源光学元件的数据中心内的带宽的聚合和解聚
公开(公告)号：US09225454B1
公开(公告)日：2015-12-29
申请号：US13282229
申请日：2011-10-26
申请人： Hong Liu , Amin Vahdat , Ryohei Urata , Xiaoxue Zhao , Chris Johnson
发明人： Hong Liu , Amin Vahdat , Ryohei Urata , Xiaoxue Zhao , Chris Johnson
IPC分类号： H04J14/02
CPC分类号： H04J14/02
摘要： The specification describes an apparatus including a plurality of communication ports, each communication port coupled to a corresponding networking element, and a plurality of optical transceivers, each optical transceiver coupled to a corresponding communication port and including an optical receiver and an optical transmitter, wherein the optical transmitter can transmit an optical data signal having a carrier wavelength different than any other of the plurality of optical transmitters. A passive optical multiplexer/demultiplexer module is coupled to the transceivers and includes an optical multiplexer including a wavelength division multiplexing (WDM) output and a plurality of inputs, each input coupled to one of the plurality of transmitters, and an optical demultiplexer including a WDM input and a plurality of outputs, each output coupled to one of the plurality of receivers. Placing the passive optical multiplexer and demultiplexer external to the optical transceivers creates an aggregation/de-aggregation point with extremely low fault probability.
摘要翻译：本说明书描述了一种包括多个通信端口，耦合到对应的网络元件的每个通信端口和多个光收发器的设备，每个光收发器耦合到对应的通信端口并且包括光接收器和光发射器，其中，光发射机可以发射具有不同于多个光发射机中任何其它的载波波长的光数据信号。无源光复用器/解复用器模块耦合到收发器，并且包括光复用器，其包括波分多路复用（WDM）输出和多个输入，每个输入耦合到所述多个发射机之一，以及光解复用器，包括WDM 输入和多个输出，每个输出耦合到所述多个接收器中的一个。将无源光复用器和解复用器放置在光收发器外部，创建具有极低故障概率的聚合/解聚合点。

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