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1. 发明授权

US07110816B2 Reduction of left-ventricular offset interaction with tachyarrhythmia detection 有权
公开(公告)号：US07110816B2
公开(公告)日：2006-09-19
申请号：US10878953
申请日：2004-06-28
申请人： Kenneth L. Baker , David L. Perschbacher , Andrew P. Kramer , Jeffrey E. Stahmann
发明人： Kenneth L. Baker , David L. Perschbacher , Andrew P. Kramer , Jeffrey E. Stahmann
IPC分类号： A61N1/365
CPC分类号： A61N1/3627 , A61N1/3684
摘要： A device and method for improving tachyarrhythmia detection when the ventricles are resynchronized by delivering paces to both ventricles separated by a specified offset interval. Timing of escape intervals and tachyarrhythmia detection is based upon senses from one of the ventricles designated as a rate ventricle. A reversion pacing mode is provided in order to prevent tachyarrhythmia detection from being compromised when the rate ventricle is paced after the other ventricle.

2. 发明授权

US06757562B2 Reduction of left-ventricular offset interaction with tachyarrhythmia detection 有权
标题翻译：减慢与心律失常检测的左心室偏移相互作用
公开(公告)号：US06757562B2
公开(公告)日：2004-06-29
申请号：US10037444
申请日：2001-10-25
申请人： Kenneth L. Baker , David L. Perschbacher , Andrew P. Kramer , Jeffrey E. Stahmann
发明人： Kenneth L. Baker , David L. Perschbacher , Andrew P. Kramer , Jeffrey E. Stahmann
IPC分类号： A61N1362
CPC分类号： A61N1/3627 , A61N1/3684
摘要： A device and method for improving tachyarrhythmia detection when the ventricles are resynchronized by delivering paces to both ventricles separated by a specified offset interval. Timing of escape intervals and tachyarrhythmia detection is based upon senses from one of the ventricles designated as a rate ventricle. A reversion pacing mode is provided in order to prevent tachyarrhythmia detection from being compromised when the rate ventricle is paced after the other ventricle.
摘要翻译：通过向两个心室分配指定的偏移间隔来逐步重新同步心室，从而改善快速性心律失常检测的装置和方法。逃避间隔和快速性心律失常检测的时间是基于指定为速率心室的心室之一的感觉。提供回波起搏模式，以便当速率心室在另一脑室之后起搏时，防止快速性心律失常检测受到损害。

3. 发明授权

US07801609B2 Reduction of left-ventricular offset interaction with tachyarrhythmia detection 有权
标题翻译：减慢与心律失常检测的左心室偏移相互作用
公开(公告)号：US07801609B2
公开(公告)日：2010-09-21
申请号：US11522691
申请日：2006-09-18
申请人： Kenneth L. Baker , David L. Perschbacher , Andrew P. Kramer , Jeffrey E. Stahmann
发明人： Kenneth L. Baker , David L. Perschbacher , Andrew P. Kramer , Jeffrey E. Stahmann
IPC分类号： A61N1/00
CPC分类号： A61N1/3627 , A61N1/3684
摘要： A device and method for improving tachyarrhythmia detection when the ventricles are resynchronized by delivering paces to both ventricles separated by a specified offset interval. Timing of escape intervals and tachyarrhythmia detection is based upon senses from one of the ventricles designated as a rate ventricle. A reversion pacing mode is provided in order to prevent tachyarrhythmia detection from being compromised when the rate ventricle is paced after the other ventricle.
摘要翻译：通过向两个心室分配指定的偏移间隔来逐步重新同步心室，从而改善快速性心律失常检测的装置和方法。逃避间隔和快速性心律失常检测的时间是基于指定为速率心室的心室之一的感觉。提供回波起搏模式，以便当速率心室在另一脑室之后起搏时，防止快速性心律失常检测受到损害。

4. 发明授权

US06427084B2 Multi-site hybrid hardware-based cardiac pacemaker 有权
标题翻译：多站点混合硬件心脏起搏器
公开(公告)号：US06427084B2
公开(公告)日：2002-07-30
申请号：US09514813
申请日：2000-02-28
申请人： Kenneth L. Baker , Doug M. Birkholz , David L. Perschbacher , Andrew P. Kramer , Gary T. Seim
发明人： Kenneth L. Baker , Doug M. Birkholz , David L. Perschbacher , Andrew P. Kramer , Gary T. Seim
IPC分类号： A61N1362
CPC分类号： A61N1/368 , A61N1/3622 , A61N1/3684
摘要： A hybrid cardiac pacemaker in which the operation of the device is controlled by hardware-based controller as supervised by a microprocessor-based controller. The hardware-based controller comprises a plurality of timers that expire when they reach timer limit values stored in registers updatable by the microprocessor, and a combinational logic array for causing the device to generate pace outputs in accordance with timer expirations and sense signals. The combinational logic array may operate the pacemaker in a number of programmed modes in accordance with a mode value stored in a mode control register by the microprocessor.
摘要翻译：一种混合心脏起搏器，其中由基于微处理器的控制器监控的由基于硬件的控制器控制该设备的操作。基于硬件的控制器包括多个定时器，当它们达到存储在可由微处理器更新的寄存器中的定时器限制值时，该定时器到期，以及组合逻辑阵列，用于使该设备根据定时器期满和感测信号产生步进输出。组合逻辑阵列可以根据由微处理器存储在模式控制寄存器中的模式值，以多种编程模式操作起搏器。

5. 发明授权

US06920355B2 Multi-site hybrid hardware-based cardiac pacemaker 有权
标题翻译：多站点混合硬件心脏起搏器
公开(公告)号：US06920355B2
公开(公告)日：2005-07-19
申请号：US10150297
申请日：2002-05-17
申请人： Kenneth L. Baker , Doug M. Birkholz , David L. Perschbacher , Andrew P. Kramer , Gary T. Seim
发明人： Kenneth L. Baker , Doug M. Birkholz , David L. Perschbacher , Andrew P. Kramer , Gary T. Seim
IPC分类号： A61N1/362 , A61N1/368
CPC分类号： A61N1/368 , A61N1/3622 , A61N1/3684
摘要： A hybrid cardiac pacemaker in which the operation of the device is controlled by hardware-based controller as supervised by a microprocessor-based controller. The hardware-based controller comprises a plurality of timers that expire when they reach timer limit values stored in registers updatable by the microprocessor, and a combinational logic array for causing the device to generate pace outputs in accordance with timer expirations and sense signals. The combinational logic array may operate the pacemaker in a number of programmed modes in accordance with a mode value stored in a mode control register by the microprocessor.
摘要翻译：一种混合心脏起搏器，其中由基于微处理器的控制器监控的由基于硬件的控制器控制该设备的操作。基于硬件的控制器包括多个定时器，当它们达到存储在可由微处理器更新的寄存器中的定时器限制值时，该定时器到期，以及组合逻辑阵列，用于使该设备根据定时器期满和感测信号产生步进输出。组合逻辑阵列可以根据由微处理器存储在模式控制寄存器中的模式值，以多种编程模式操作起搏器。

6. 发明授权

US08649860B2 Adaptive event storage in implantable device 有权
标题翻译：可植入装置中的自适应事件存储
公开(公告)号：US08649860B2
公开(公告)日：2014-02-11
申请号：US12781459
申请日：2010-05-17
申请人： Yanting Dong , David L. Perschbacher , Jeffrey E. Stahmann , Dan Li , Deepa Mahajan
发明人： Yanting Dong , David L. Perschbacher , Jeffrey E. Stahmann , Dan Li , Deepa Mahajan
IPC分类号： A61N1/39
CPC分类号： A61N1/37252 , A61B5/02 , A61B5/04 , A61B5/0452 , A61B5/6846 , A61N1/025 , A61N1/3621 , A61N1/3702 , A61N1/372 , A61N1/3925
摘要： Monitoring physiological parameter using an implantable physiological monitor in order to detect a condition predictive of a possible future pathological episode and collecting additional physiological data associated with the condition predictive of a possible future pathological episode. Monitoring another physiological parameter in order to detect a condition indicative of the beginning of a present pathological episode and collecting additional pathological data in response to the condition. Determining that the condition predictive of a future episode and the condition indicative of a present episode are associated and, in response thereto, storing all the collected physiological data.
摘要翻译：使用植入式生理监测器监测生理参数，以便检测预测可能的未来病理发作的状况并收集与预测可能的未来病理发作相关的条件相关的附加生理数据。监测另一个生理参数，以便检测指示本病理发作开始的病症，并根据病情收集额外的病理资料。确定预测未来事件的状况和指示当前情节的状况是相关联的，并且响应于此，存储所有收集的生理数据。

7. 发明申请

US20100305642A1 ADAPTIVE EVENT STORAGE IN IMPLANTABLE DEVICE 有权
标题翻译：可插入设备中的自适应事件存储
公开(公告)号：US20100305642A1
公开(公告)日：2010-12-02
申请号：US12781459
申请日：2010-05-17
申请人： Yanting Dong , David L. Perschbacher , Jeffrey E. Stahmann , Dan Li , Deepa Mahajan
发明人： Yanting Dong , David L. Perschbacher , Jeffrey E. Stahmann , Dan Li , Deepa Mahajan
IPC分类号： A61N1/00
CPC分类号： A61N1/37252 , A61B5/02 , A61B5/04 , A61B5/0452 , A61B5/6846 , A61N1/025 , A61N1/3621 , A61N1/3702 , A61N1/372 , A61N1/3925
摘要： Monitoring physiological parameter using an implantable physiological monitor in order to detect a condition predictive of a possible future pathological episode and collecting additional physiological data associated with the condition predictive of a possible future pathological episode. Monitoring another physiological parameter in order to detect a condition indicative of the beginning of a present pathological episode and collecting additional pathological data in response to the condition. Determining that the condition predictive of a future episode and the condition indicative of a present episode are associated and, in response thereto, storing all the collected physiological data.
摘要翻译：使用植入式生理监测器监测生理参数，以便检测预测可能的未来病理发作的状况并收集与预测可能的未来病理发作相关的条件相关的附加生理数据。监测另一个生理参数，以便检测指示本病理发作开始的病症，并根据病情收集额外的病理资料。确定预测未来事件的状况和指示当前情节的状况是相关联的，并且响应于此，存储所有收集的生理数据。

8. 发明授权

US07376461B2 Dynamic mode switch for early detection of tachyarrhythmia 有权
标题翻译：用于早发性快速性心律失常的动态模式切换
公开(公告)号：US07376461B2
公开(公告)日：2008-05-20
申请号：US10274697
申请日：2002-10-18
申请人： David L. Perschbacher , Kenneth L. Baker
发明人： David L. Perschbacher , Kenneth L. Baker
IPC分类号： A61N1/365
CPC分类号： A61N1/3622 , A61N1/3684
摘要： An algorithm executed in an implantable cardiac rhythm management device (CRMD) automatically adjusts the time that an atrial pace (AP) and/or a ventricular pace (VP) pulse is generated by a pulse generator when the expected time of occurrence of the AP pulse falls within a predetermined interval referred to as the “lowest tachy zone”. By delaying the generation of the AP pulse until outside of the lowest tachy zone, undersensing of ventricular tachycardia depolarizations due to cross-channel refractory and VP refractory is avoided.
摘要翻译：在可植入心律管理装置（CRMD）中执行的算法在预期的AP脉冲发生时间时自动调节由脉冲发生器产生心房速度（AP）和/或心室起搏（VP）脉冲的时间落在被称为“最低速度区”的预定间隔内。通过延迟AP脉冲的产生直到最低速度区域的外部，避免了由于交叉通道耐火材料和VP耐火材料引起的室性心动过速去极化的不足。

9. 发明授权

US07844332B2 Atrioventricular delay adjustment enhancing ventricular tachyarrhythmia detection 有权
标题翻译：房室延迟调整增强室性快速性心律失常检测
公开(公告)号：US07844332B2
公开(公告)日：2010-11-30
申请号：US11676464
申请日：2007-02-19
申请人： David L. Perschbacher , Kenneth L. Baker
发明人： David L. Perschbacher , Kenneth L. Baker
IPC分类号： A61N1/365
CPC分类号： A61N1/3622 , A61N1/3684
摘要： This document discusses, among other things, an apparatus comprising an atrial sensing circuit, a ventricular sensing circuit and an atrioventricular (AV) delay adjustment circuit. The atrial sensing circuit detects a first fast atrial pace that concludes a timing interval that is shorter than or equal to a first threshold value. The ventricular sensing circuit detects a first condition that comprises a sensed intrinsic first fast ventricular contraction that occurs within a specified first period of a most recently detected first fast atrial pace. The fast ventricular contraction concludes a timing interval that is shorter than or equal to a second threshold value. The AV delay adjustment circuit attempts to decrease an AV delay at least in part in response to detecting the first condition. Other apparatuses and methods are disclosed.
摘要翻译：本文件尤其涉及包括心房感测电路，心室感测电路和房室（AV）延迟调节电路的装置。心房感测电路检测到第一快速心房速度，其结束短于或等于第一阈值的定时间隔。心室感测电路检测包括感测到的内在的第一快速心室收缩的第一状况，其发生在最近检测的第一快速心房步速的指定的第一时段内。快速心室收缩结束时间间隔短于或等于第二阈值。至少部分地响应于检测到第一条件，AV延迟调整电路尝试减小AV延迟。公开了其他装置和方法。

10. 发明授权

US08473042B2 Tachyarrhythmia detection using dynamic duration 有权
标题翻译：快速心律失常检测采用动态持续时间
公开(公告)号：US08473042B2
公开(公告)日：2013-06-25
申请号：US12794346
申请日：2010-06-04
申请人： Jason McCarthy , David L. Perschbacher
发明人： Jason McCarthy , David L. Perschbacher
IPC分类号： A61B5/0464
CPC分类号： A61N1/3621 , A61B5/046
摘要： An apparatus comprises an implantable cardiac signal sensing circuit configured to produce a sensed cardiac signal representative of cardiac activity of a subject and a controller communicatively coupled to the cardiac signal sensing circuit. The controller includes a sensing module configured to detect a cardiac depolarization using the sensed cardiac signal and an arrhythmia detection module. The arrhythmia detection module is configured to detect a depolarization rate or interval that satisfies a first tachyarrhythmia detection rate zone threshold, adjust a specified detection duration threshold for the tachyarrhythmia detection zone according to the detected depolarization rate, declare that the detected depolarization rate is an episode of tachyarrhythmia when the detected depolarization rate is sustained for the adjusted detection duration threshold, and provide an indication of the tachyarrhythmia to a user or process.
摘要翻译：一种装置包括可植入心脏信号感测电路，其被配置为产生代表受试者的心脏活动的感测心脏信号和通信地耦合到心脏信号感测电路的控制器。控制器包括感测模块，其被配置为使用感测的心脏信号和心律失常检测模块来检测心脏去极化。心律失常检测模块被配置为检测满足第一快速心律失常检测率区域阈值的去极化速率或间隔，根据检测到的去极化速率调整快速心律失常检测区域的指定检测持续时间阈值，声明检测到的去极化率是发作当检测到的去极化速率维持在调整的检测持续时间阈值时，并且向使用者或过程提供快速性心律失常的指示，发生快速性心律失常。

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