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1. 发明申请

US20100038530A1 Mass Spectrometer 有权
标题翻译：质谱仪
公开(公告)号：US20100038530A1
公开(公告)日：2010-02-18
申请号：US11813221
申请日：2006-01-17
申请人： Kevin Giles , Martin Green , Jason Lee Wildgoose
发明人： Kevin Giles , Martin Green , Jason Lee Wildgoose
IPC分类号： H01J49/04 , H01J49/42
CPC分类号： H01J49/4235 , H01J49/4275
摘要： An ion guide or ion trap (1) is disclosed comprising a segmented linear ion guide or ion trap. Ions are confined radially within the ion guide or ion trap (1) by the application of an AC or RF voltage to the electrodes. A static potential well is maintained along at least a portion of the axial length of the ion guide or ion trap (1). A time varying homogeneous electric field is applied along at least a portion of the axial length of the ion guide or ion trap (1). The combination of the static axial potential well and the time varying axial homogeneous electric field causes ions to be ejected from the ion guide or ion trap (1) in a substantially non-resonant manner.
摘要翻译：公开了一种离子导向器或离子阱（1），其包括分段线性离子导向器或离子阱。通过向电极施加AC或RF电压，离子在径向上被限制在离子导向器或离子阱（1）内。沿离子导向器或离子阱（1）的轴向长度的至少一部分保持静电势阱。沿离子导向器或离子阱（1）的轴向长度的至少一部分施加时变均匀电场。静态轴向势阱和随时间变化的轴向均匀电场的组合导致离子以基本上非共振的方式从离子导向器或离子阱（1）喷出。

2. 发明授权

US08519328B2 Mass spectrometer 有权
标题翻译：质谱仪
公开(公告)号：US08519328B2
公开(公告)日：2013-08-27
申请号：US13435877
申请日：2012-03-30
申请人： Kevin Giles , Martin Green , Jason Lee Wildgoose , Steven Derek Pringle
发明人： Kevin Giles , Martin Green , Jason Lee Wildgoose , Steven Derek Pringle
IPC分类号： H01J49/26
CPC分类号： H01J49/427 , H01J49/4235
摘要： An ion guide or ion trap is disclosed having an entrance electrode and an exit electrode. The potential of the exit electrode is periodically dropped for a relatively short period of time allowing some ions to escape from the ion guide or ion trap via an aperture in the exit electrode. The period of time that the potential of the exit electrode is dropped for is progressively increased and ions emerge from the ion guide or ion trap in a mass to charge ratio dependent manner. The ion guide or ion trap may be operated as a mass separator or low resolution mass analyzer.
摘要翻译：公开了一种具有入口电极和出射电极的离子导向器或离子阱。出口电极的电位周期性地下降相当短的时间段，允许一些离子通过出射电极的孔离开离子导向器或离子阱。出口电极的电位下降的时间段逐渐增加，并且离子导向器或离子阱以质荷比依赖的方式出现离子。离子导向器或离子阱可以作为质量分离器或低分辨率质量分析器来操作。

3. 发明申请

US20090121123A1 Mass Spectrometer 有权
标题翻译：质谱仪
公开(公告)号：US20090121123A1
公开(公告)日：2009-05-14
申请号：US11916438
申请日：2006-06-05
申请人： Kevin Giles , Martin Green , Steven Derek Pringle , Jason Lee Wildgoose
发明人： Kevin Giles , Martin Green , Steven Derek Pringle , Jason Lee Wildgoose
IPC分类号： B01D59/44 , H01J49/00
CPC分类号： H01J49/427 , H01J49/4235
摘要： An ion guide or ion trap (1) is disclosed having an entrance electrode (2) and an exit electrode (3). The potential of the exit electrode (3) is periodically dropped for a relatively short period of time allowing some ions to escape from the ion guide or ion trap (1) via an aperture in the exit electrode (3). The period of time that the potential of the exit electrode (3) is dropped for is progressively increased and ions emerge from the ion guide or ion trap (1) in a mass to charge ratio dependent manner. The ion guide or ion trap (1) may be operated as a mass separator or low resolution mass analyser.
摘要翻译：公开了一种具有入口电极（2）和出口电极（3）的离子导向器或离子阱（1）。出口电极（3）的电位周期性地下降相当短的时间段，允许一些离子通过出射电极（3）中的孔从离子导向器或离子阱（1）逸出。退出电极（3）的电位下降的时间段逐渐增加，并且离子导向器或离子阱（1）以质荷比依赖的方式出现离子。离子导向器或离子阱（1）可以作为质量分离器或低分辨率质量分析器来操作。

4. 发明授权

US09460906B2 Mass spectrometer 有权
标题翻译：质谱仪
公开(公告)号：US09460906B2
公开(公告)日：2016-10-04
申请号：US11813221
申请日：2006-01-17
申请人： Kevin Giles , Martin Green , Jason Lee Wildgoose
发明人： Kevin Giles , Martin Green , Jason Lee Wildgoose
IPC分类号： H01J49/26 , H01J49/42
CPC分类号： H01J49/4235 , H01J49/4275
摘要： An ion guide or ion trap is disclosed comprising a segmented linear ion guide or ion trap. Ions are confined radially within the ion guide or ion trap by the application of an AC or RF voltage to the electrodes. A static potential well is maintained along at least a portion of the axial length of the ion guide or ion trap. A time varying homogeneous electric field is applied along at least a portion of the axial length of the ion guide or ion trap. The combination of the static axial potential well and the time varying axial homogeneous electric field causes ions to be ejected from the ion guide or ion trap in a substantially non-resonant manner.
摘要翻译：公开了一种离子导向器或离子阱，其包括分段线性离子导向器或离子阱。通过向电极施加AC或RF电压，离子限制在离子导向器或离子阱内径向。沿着离子导向器或离子阱的轴向长度的至少一部分保持静电势阱。沿着离子导向器或离子阱的轴向长度的至少一部分施加时变均匀电场。静态轴向势阱和随时间变化的轴向均匀电场的组合导致离子以基本上非共振的方式从离子导向器或离子阱排出。

5. 发明授权

US08153960B2 Mass spectrometer 有权
标题翻译：质谱仪
公开(公告)号：US08153960B2
公开(公告)日：2012-04-10
申请号：US11916438
申请日：2006-06-05
申请人： Kevin Giles , Martin Green , Steven Derek Pringle , Jason Lee Wildgoose
发明人： Kevin Giles , Martin Green , Steven Derek Pringle , Jason Lee Wildgoose
IPC分类号： H01J49/26
CPC分类号： H01J49/427 , H01J49/4235
摘要： An ion guide or ion trap (1) is disclosed having an entrance electrode (2) and an exit electrode (3). The potential of the exit electrode (3) is periodically dropped for a relatively short period of time allowing some ions to escape from the ion guide or ion trap (1) via an aperture in the exit electrode (3). The period of time that the potential of the exit electrode (3) is dropped for is progressively increased and ions emerge from the ion guide or ion trap (1) in a mass to charge ratio dependent manner. The ion guide or ion trap (1) may be operated as a mass separator or low resolution mass analyser.
摘要翻译：公开了一种具有入口电极（2）和出口电极（3）的离子导向器或离子阱（1）。出口电极（3）的电位周期性地下降相当短的时间段，允许一些离子通过出射电极（3）中的孔从离子导向器或离子阱（1）逸出。退出电极（3）的电位下降的时间段逐渐增加，并且离子导向器或离子阱（1）以质荷比依赖的方式出现离子。离子导向器或离子阱（1）可以作为质量分离器或低分辨率质量分析器来操作。

6. 发明授权

US08847153B2 Segmented ion trap mass spectrometer 有权
标题翻译：分段离子阱质谱仪
公开(公告)号：US08847153B2
公开(公告)日：2014-09-30
申请号：US11722970
申请日：2006-01-17
申请人： Kevin Giles , Martin Green , Jason Lee Wildgoose
发明人： Kevin Giles , Martin Green , Jason Lee Wildgoose
IPC分类号： H01J49/00 , H01J49/42
CPC分类号： H01J49/4235 , H01J49/4275
摘要： An ion guide or ion trap 1 is disclosed comprising a segmented linear ion guide or ion trap. Ions are confined radially within the ion guide or ion trap 1 by the application of an AC or RF voltage to the electrodes. Ions are trapped within an axial quadratic potential well which is oscillated or modulated axially so as to cause ions to be ejected from the ion guide or ion trap 1 in a substantially non-resonant manner.
摘要翻译：公开了一种离子导向器或离子阱1，其包括分段线性离子导向器或离子阱。通过向电极施加AC或RF电压，离子限制在离子导向器或离子阱1的径向内。离子被捕获在轴向二次势阱内，其轴向振荡或调制，从而使离子以基本上非共振的方式从离子导向器或离子阱1喷出。

7. 发明申请

US20120199734A1 Mass Spectrometer 有权
标题翻译：质谱仪
公开(公告)号：US20120199734A1
公开(公告)日：2012-08-09
申请号：US13435877
申请日：2012-03-30
申请人： Kevin Giles , Martin Green , Steven Derek Pringle , Jason Lee Wildgoose
发明人： Kevin Giles , Martin Green , Steven Derek Pringle , Jason Lee Wildgoose
IPC分类号： H01J49/40 , H01J49/26
CPC分类号： H01J49/427 , H01J49/4235
摘要： An ion guide or ion trap is disclosed having an entrance electrode and an exit electrode. The potential of the exit electrode is periodically dropped for a relatively short period of time allowing some ions to escape from the ion guide or ion trap via an aperture in the exit electrode. The period of time that the potential of the exit electrode is dropped for is progressively increased and ions emerge from the ion guide or ion trap in a mass to charge ratio dependent manner. The ion guide or ion trap may be operated as a mass separator or low resolution mass analyser.
摘要翻译：公开了一种具有入口电极和出射电极的离子导向器或离子阱。出口电极的电位周期性地下降相当短的时间段，允许一些离子通过出射电极的孔离开离子导向器或离子阱。出口电极的电位下降的时间段逐渐增加，并且离子导向器或离子阱以质荷比依赖的方式出现离子。离子导向器或离子阱可以作为质量分离器或低分辨率质量分析器来操作。

8. 发明授权

US07683314B2 Mass spectrometer 有权
标题翻译：质谱仪
公开(公告)号：US07683314B2
公开(公告)日：2010-03-23
申请号：US10599572
申请日：2005-04-04
申请人： Martin Green , Jason Lee Wildgoose , Steven Derek Pringle , Kevin Giles
发明人： Martin Green , Jason Lee Wildgoose , Steven Derek Pringle , Kevin Giles
IPC分类号： H01J49/04
CPC分类号： H01J49/06 , Y10T436/24
摘要： A mass spectrometer is disclosed comprising an ion beam attenuator which attenuates an ion beam repeatedly switching between a zero transmission mode of operation during a time period ΔT1 and a non-zero transmission mode of operation during a time period ΔT2. The degree of attenuation of the ion beam can be varied by varying the mark space ratio ΔT2/ΔT1. The ion beam attenuator may release ions in packets or pulses but the packets or pulses of ions may be converted into a continuous ion beam by a relatively high pressure ion guide or gas collision cell arranged downstream of the ion beam attenuator.
摘要翻译：公开了一种质谱仪，其包括离子束衰减器，该离子束衰减器衰减离子束在时间段Dgr; T1期间的零传输操作模式和在时间段Dgr; T2期间的非零传输操作模式之间重复切换。可以通过改变标记空间比＆Dgr; T2 /＆Dgr; T1来改变离子束的衰减程度。离子束衰减器可以以分组或脉冲的形式释放离子，但是离子束或脉冲可以通过布置在离子束衰减器下游的相对高压的离子导向器或气体碰撞元件转换为连续的离子束。

9. 发明申请

US20090014637A1 Mass Spectrometer 有权
标题翻译：质谱仪
公开(公告)号：US20090014637A1
公开(公告)日：2009-01-15
申请号：US11722970
申请日：2006-01-17
申请人： Kevin Giles , Martin Green , Jason Lee Wildgoose
发明人： Kevin Giles , Martin Green , Jason Lee Wildgoose
IPC分类号： B01D59/44
CPC分类号： H01J49/4235 , H01J49/4275
摘要： An ion guide or ion trap 1 is disclosed comprising a segmented linear ion guide or ion trap. Ions are confined radially within the ion guide or ion trap 1 by the application of an AC or RF voltage to the electrodes. Ions are trapped within an axial quadratic potential well which is oscillated or modulated axially so as to cause ions to be ejected from the ion guide or ion trap 1 in a substantially non-resonant manner.
摘要翻译：公开了一种离子导向器或离子阱1，其包括分段线性离子导向器或离子阱。通过向电极施加AC或RF电压，离子限制在离子导向器或离子阱1的径向内。离子被捕获在轴向二次势阱内，其轴向振荡或调制，从而使离子以基本上非共振的方式从离子导向器或离子阱1喷出。

10. 发明授权

US09685313B2 Combined mass-to-charge ratio and charge state selection in tandem mass spectrometry 有权
公开(公告)号：US09685313B2
公开(公告)日：2017-06-20
申请号：US12514972
申请日：2007-11-15
申请人： Robert Harold Bateman , Kevin Giles , Steven Derek Pringle , Jason Lee Wildgoose
发明人： Robert Harold Bateman , Kevin Giles , Steven Derek Pringle , Jason Lee Wildgoose
IPC分类号： H01J49/00 , H01J49/42 , G01N27/62
CPC分类号： H01J49/4215 , G01N27/622 , H01J49/004 , H01J49/426
摘要： A mass spectrometer is disclosed comprising an ion mobility spectrometer and an ion gate. A collision cell is arranged downstream of the ion gate. The operation of the ion mobility spectrometer and the ion gate are synchronised so that only ions having a particular mass to charge ratio and a desired charge state are onwardly transmitted to the collision cell.

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