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1. 发明授权

US06379346B1 Introducer system 有权
标题翻译：介绍系统
公开(公告)号：US06379346B1
公开(公告)日：2002-04-30
申请号：US09552250
申请日：2000-04-18
申请人： Michael E. McIvor , Kenneth C. Gardeski , Pedro A. Meregotte , Matthew D. Bonner , Timothy G. Laske , Linda L. Lach
发明人： Michael E. McIvor , Kenneth C. Gardeski , Pedro A. Meregotte , Matthew D. Bonner , Timothy G. Laske , Linda L. Lach
IPC分类号： A61M2500
CPC分类号： A61M25/0668 , A61M25/01 , A61M2025/0675
摘要： An introducer is structured with an elongated tube having first and second lumens. A molded handle is coupled to the proximal end of the tube with an opening aligned with the first lumen. Further, a wall adjacent the opening of the handle defines a slot and is located diametrically opposite the second lumen. A tubular reinforcement member is located within the second lumen and the handle is provided with a second opening, thereby having a communication with the second lumen. In another embodiment a lead/catheter introducer includes an implantable lead or catheter having an elongated first lumen through which the lead or catheter passes and a second lumen extends parallel to the first lumen along at least a distal portion thereof. A tubular reinforcement member is disposed within the second lumen. The tubular reinforcement member further includes an internal lumen and a curvable stylet disposed in the lumen.
摘要翻译：导引器构造有具有第一和第二腔的细长管。模制手柄与管的近端连接，开口与第一内腔对准。此外，与手柄的开口相邻的壁限定了狭槽，并且位于与第二内腔完全相对的位置。管状加强构件位于第二内腔内，手柄设置有第二开口，从而与第二腔相连通。在另一个实施例中，引导/导管导引器包括具有细长的第一内腔的可植入引线或导管，所述引导件或导管通过所述细长的第一内腔，并且沿其至少其远端部分平行于所述第一内腔延伸的第二腔。管状加强构件设置在第二内腔内。管状加强构件还包括内腔和设置在内腔中的可调节探针。

2. 发明授权

US06280433B1 Introducer system 有权
标题翻译：介绍系统
公开(公告)号：US06280433B1
公开(公告)日：2001-08-28
申请号：US09392715
申请日：1999-09-09
申请人： Michael E. McIvor , Kenneth C. Gardeski , Pedro A. Meregotte , Mathew D. Bonner , Timothy G. Laske , Linda L. Lach
发明人： Michael E. McIvor , Kenneth C. Gardeski , Pedro A. Meregotte , Mathew D. Bonner , Timothy G. Laske , Linda L. Lach
IPC分类号： A61M2500
CPC分类号： A61M25/0668 , A61M25/01 , A61M2025/0675
摘要： An introducer or guide catheter for directing an implantable medical device such as a lead or catheter to a desired location within a patient's body. In one embodiment of the invention, the introducer comprises a two-lumen tube. A first lumen is configured to receive the implantable medical device that is to be introduced. A second lumen is provided to receive an insertable, elongated guiding member such as a stylet, which may be shapable in various orientations, and which may be used to alter the configuration of the introducer. The second lumen may be provided with an internal coil or other tubular reinforcement member to prevent perforation of this lumen by the guiding member when the introducer is in the patient's body. In order to facilitate removal of the introducer over an implantable medical device having a connector or fitting that is larger than the internal diameter of the first lumen, the introducer may be adapted to be slit or split along its length. In some embodiments of the invention, the introducer may be rendered splittable by provision of a weakened zone along its length. According to yet another aspect of the invention, the introducer may be provided with a luer lock at its proximal end to facilitate connection of the introducer to a hemostasis valve, t-fitting, or the like.
摘要翻译：导引器或引导导管，用于将诸如引线或导管的可植入医疗装置引导到患者体内的期望位置。在本发明的一个实施例中，导引器包括两腔管。第一管腔被配置为接收待引入的可植入医疗装置。提供第二内腔以接收可插入的细长引导构件，例如探针，其可以以各种取向成形，并且其可以用于改变导引器的构造。第二内腔可以设置有内部线圈或其他管状加强构件，以在导引器位于患者体内时防止引导构件对该内腔穿孔。为了便于在具有大于第一内腔的内径的连接器或配件的可植入医疗装置上移除导引器，导引器可以适于沿着其长度被切割或分开。在本发明的一些实施例中，导引器可以通过沿着其长度提供弱化区域而被分解。根据本发明的另一方面，导引器在其近端可以设置有鲁尔锁，以便于将导引器连接到止血阀，t形配件等。

3. 发明授权

US06733500B2 Method and system for delivering a medical electrical lead within a venous system 有权
标题翻译：用于在静脉系统内递送医用电线的方法和系统
公开(公告)号：US06733500B2
公开(公告)日：2004-05-11
申请号：US10131672
申请日：2002-04-24
申请人： James F. Kelley , James H. Vaughn , Stanten C. Spear , Douglas S. Hine , Kenneth C. Gardeski , Vicki L. Bjorklund , Pedro A. Meregotte , John L. Sommer , John J. Maier
发明人： James F. Kelley , James H. Vaughn , Stanten C. Spear , Douglas S. Hine , Kenneth C. Gardeski , Vicki L. Bjorklund , Pedro A. Meregotte , John L. Sommer , John J. Maier
IPC分类号： A61B1818
CPC分类号： A61M25/0138 , A61B18/1492 , A61B2017/22038 , A61M25/005 , A61M25/0054 , A61M25/0141 , A61M25/0147 , A61M25/0668 , A61M25/09 , A61M25/09041 , A61M2025/0042 , A61M2025/0047 , A61M2025/0081 , A61M2025/0161 , A61M2025/0681 , A61M2025/1052 , A61M2025/1079 , A61N1/056 , A61N1/06 , A61N1/372 , A61N2001/0578 , A61N2001/0585
摘要： A loading device for loading a guide wire within a medical electrical lead that includes a navigation portion, having an outer portion, and extending from a front end to a back end, and having an opening formed at the back end. An engagement cavity receives and properly orientates the lead distal tip to align the lumen of the lead with the opening of the navigation portion during the loading of the guide wire within the lead. A first side wall is spaced from a second side wall to form a slot extending along the outer portion from the front end to the back end of the navigation portion, and the guide wire is advanced through the slot as the lead having the guide wire loaded therein is removed from the loading device.
摘要翻译：一种用于将导丝装载在医疗用电线内的装载装置，其包括具有外部的导航部，并且从前端延伸到后端，并且具有形成在后端的开口。接合腔容纳并适当地定向引线远侧末端，以在引导线在引线内的加载期间使引线的内腔与引导部分的开口对准。第一侧壁与第二侧壁间隔开以形成沿着导引部分的前端到后端的外部部分延伸的狭槽，并且当导线加载有引导线时，引导线前进通过狭槽其中的装载装置被移除。

4. 发明授权

US5928277A One piece defibrillation lead circuit 失效
标题翻译：一片除颤引线电路
公开(公告)号：US5928277A
公开(公告)日：1999-07-27
申请号：US26064
申请日：1998-02-19
申请人： Timothy G. Laske , David W. Mayer , Pedro A. Meregotte , Bret R. Shoberg , Gregory A. Boser
发明人： Timothy G. Laske , David W. Mayer , Pedro A. Meregotte , Bret R. Shoberg , Gregory A. Boser
IPC分类号： A61N1/05
CPC分类号： A61N1/0563
摘要： An implantable electrical lead having a lead body with a longitudinal lumen therein and a stranded electrical conductor located in the lumen and which exits the lumen at a distal portion of the lead body, the distal end of the conductor being curved to form a loop and reentering the lumen, terminating within the lumen alongside a more proximal portion of the conductor. The portion of the conductor exterior to the lumen is wound around the lead body to form a coiled electrode. In some embodiments the distal end of the conductor is coupled to a more proximal portion of the conductor to form a loop and the loop is wound around the lead body to form a bifilar coil. In other embodiments the conductor is wound around the lead body to form a mono-filar coil. The distal end of the conductor is mechanically and electrically coupled to a more proximal portion of the conductor, within the lumen.
摘要翻译：一种植入式电引线，其具有其中具有纵向内腔的引线主体和位于所述内腔中的绞合电导体，并且在所述引线主体的远端部分处离开所述内腔，所述导体的远端弯曲以形成环并重新进入该管腔与导管的较近端部分一起终止于管腔内。导管外部的导体部分缠绕在引线体上以形成线圈电极。在一些实施例中，导体的远端耦合到导体的更近端部分以形成环，并且环绕引线体缠绕以形成双线圈。在其它实施例中，导体缠绕在引线体上以形成单丝线圈。导体的远端在管腔内机械地和电耦合到导体的更靠近的部分。

5. 发明授权

US5807399A Method for removal of chronically implanted leads and leads optimized for use therewith 失效
标题翻译：用于去除长期植入的引线和优化用于其的引线的方法
公开(公告)号：US5807399A
公开(公告)日：1998-09-15
申请号：US736000
申请日：1996-10-23
申请人： Timothy G. Laske , Pedro A. Meregotte , Michael R. Dollimer
发明人： Timothy G. Laske , Pedro A. Meregotte , Michael R. Dollimer
IPC分类号： A61N1/05
CPC分类号： A61N1/057 , A61N2001/0578
摘要： A method of removing chronically implanted pacing leads and leads specifically adapted to be removed using the method. The leads are constructed so that upon tension applied to the electrode, it is withdrawn to a first location, so that upon further application of tension, the sheath located distal to the withdrawn electrode may collapse, enhancing its removability. In some embodiments of leads particularly adapted for use in conjunction with the method, the leads are provided with a mechanism for allowing breakage of the lead adjacent the points to which the electrode has been withdrawn, upon application of further tension to the electrode.
摘要翻译：使用该方法去除长期植入的起搏引线和引线的方法，其特别适于被去除。引线被构造成使得当施加到电极的张力时，其被拉出到第一位置，使得在进一步施加张力时，位于引出电极的远侧的护套可能会塌陷，从而增强其可移除性。在特别适合于与该方法一起使用的引线的一些实施例中，引线设置有用于在向电极施加进一步的张力时允许引线邻近电极已被取出的点断裂的机构。

6. 发明授权

US5676694A Medical electrical lead 失效
标题翻译：医用电线
公开(公告)号：US5676694A
公开(公告)日：1997-10-14
申请号：US657577
申请日：1996-06-07
申请人： Gregory A. Boser , Mark A. Hjelle , Timothy G. Laske , Mark Mabel , Pedro A. Meregotte , Jon M. Ocel , Clare E. Padgett , David G. Schaenzer , Bret R. Shoberg , Sandra F. Viktora
发明人： Gregory A. Boser , Mark A. Hjelle , Timothy G. Laske , Mark Mabel , Pedro A. Meregotte , Jon M. Ocel , Clare E. Padgett , David G. Schaenzer , Bret R. Shoberg , Sandra F. Viktora
IPC分类号： A61N1/05 , A61B5/042
CPC分类号： A61N1/0563
摘要： A medical electrical lead having an elongated lead body provided with an internal longitudinally extending lumen carrying an elongated stranded or cabled conductor and an electrode coil, located on said lead body. The coil is coupled to the conductor by a conductive sleeve having a tubular portion which has an internal lumen through which the conductor passes and a groove or bore which engages only a portion of a turn or turns of the electrode coil, such that the coil is oriented generally perpendicular to the internal lumen of said sleeve and to the conductor.
摘要翻译：一种具有细长引线主体的医用电引线，该引线体设置有位于所述引线主体上的内部纵向延伸的内腔，其承载细长绞合或电缆导体和电极线圈。线圈通过具有管状部分的导电套管耦合到导体，该管状部分具有导体所穿过的内腔，以及仅与电极线圈的匝或匝相接合的凹槽或孔，使得线圈为定向为大致垂直于所述套筒的内腔和导体。

7. 发明授权

US06836687B2 Method and system for delivery of a medical electrical lead within a venous system 有权
标题翻译：用于在静脉系统内递送医用电线的方法和系统
公开(公告)号：US06836687B2
公开(公告)日：2004-12-28
申请号：US10131388
申请日：2002-04-25
申请人： James F. Kelley , James H. Vaughn , Stanten C. Spear , Douglas S. Hine , Kenneth C. Gardeski , Vicki L. Bjorklund , Pedro A. Meregotte , John L. Sommer , John J. Maier
发明人： James F. Kelley , James H. Vaughn , Stanten C. Spear , Douglas S. Hine , Kenneth C. Gardeski , Vicki L. Bjorklund , Pedro A. Meregotte , John L. Sommer , John J. Maier
IPC分类号： A61N105
CPC分类号： A61M25/0138 , A61B18/1492 , A61B2017/22038 , A61M25/005 , A61M25/0054 , A61M25/0141 , A61M25/0147 , A61M25/0668 , A61M39/0613 , A61M2025/0042 , A61M2025/0047 , A61M2025/0081 , A61M2025/0161 , A61M2025/0681 , A61M2025/1052 , A61M2025/1079 , A61N1/05 , A61N1/056 , A61N2001/0578 , A61N2001/0585
摘要： A system for delivering a medical electrical lead within a coronary venous system that includes an introducer kit for establishing venous access to the coronary venous system and a plurality of delivery sheaths, each corresponding to a desired approach to a coronary sinus of the coronary venous system and insertable within the coronary venous system through the navigation pathway. A hemostasis valve is coupled to a delivery sheath of the plurality of delivery sheaths, and a guide wire is inserted within the lead lumen, guiding delivery of the distal tip of the medical electrical lead to a target site within the coronary venous system through the hemostasis valve and the delivery sheath. Subsequent to the distal tip being delivered to the target sight, the hemostasis valve is advanced over the connector of the medical electrical lead to remove the hemostasis valve from the medical electrical lead.
摘要翻译：一种用于在冠状静脉系统内递送医用电线的系统，其包括用于建立对冠状静脉系统的静脉通路的引导器套件和多个输送护套，每个输送护套对应于冠状静脉系统的冠状窦所需的方法，通过导航路径插入冠状静脉系统内。止血阀联接到多个输送护套的输送护套，并且引导线插入引导腔内，通过止血将医用电导线的远端引导到冠状静脉系统内的靶位点阀门和输送护套。在远端尖端被传送到目标瞄准器之后，止血阀在医用电线的连接器上前进，以从医用电引线上除去止血阀。

8. 发明授权

US07783365B2 Implantable medical device conductor insulation and process for forming 有权
标题翻译：可植入医疗器械导体绝缘和成型工艺
公开(公告)号：US07783365B2
公开(公告)日：2010-08-24
申请号：US10909518
申请日：2004-08-02
申请人： Michael J. Ebert , John L. Sommer , Richard D. Ries , Jordan D. Honeck , Pedro A. Meregotte , Kenneth R. Brennen
发明人： Michael J. Ebert , John L. Sommer , Richard D. Ries , Jordan D. Honeck , Pedro A. Meregotte , Kenneth R. Brennen
IPC分类号： A61N1/00
CPC分类号： H01B3/306 , A61L31/10 , A61N1/056 , C08L79/08
摘要： An elongate medical electrical lead conductor includes a layer of hydrolytically stable polyimide formed thereover.
摘要翻译：细长的医用电引线导体包括一层形成在其上的水解稳定的聚酰亚胺。

9. 发明申请

US20120136422A1 IMPLANTABLE MEDICAL DEVICE CONDUCTOR INSULATION AND PROCESS FOR FORMING 审中-公开
标题翻译：可植入医疗器械导体绝缘及其成型工艺
公开(公告)号：US20120136422A1
公开(公告)日：2012-05-31
申请号：US13367044
申请日：2012-02-06
申请人： Michael J. Ebert , John L. Sommer , Jordan D. Honeck , Richard D. Ries , Pedro A. Meregotte , Kenneth R. Brennen
发明人： Michael J. Ebert , John L. Sommer , Jordan D. Honeck , Richard D. Ries , Pedro A. Meregotte , Kenneth R. Brennen
IPC分类号： A61N1/05
CPC分类号： A61N1/056
摘要： An implantable medical device that includes a lead body extending from a proximal end to a distal end, a plurality of conductors extending between the proximal end and the distal end of the lead body, and an insulative layer formed of a hydrolytically stable polyimide material surrounding the plurality of conductors. In one embodiment, the hydrolytically stable polyimide material is an SI polyimide material.
摘要翻译：一种可植入医疗装置，其包括从近端延伸到远端的引线体，在所述引线体的近端和远端之间延伸的多根导体，以及由水解稳定的聚酰亚胺材料形成的绝缘层，多个导体。在一个实施方案中，水解稳定的聚酰亚胺材料是SI聚酰亚胺材料。

10. 发明申请

US20090306752A1 IMPLANTABLE MEDICAL DEVICE ELECTRICAL LEAD CONDUCTOR INSULATION AND PROCESS FOR FORMING 审中-公开
标题翻译：可植入医疗器械电导体导体绝缘和成型工艺
公开(公告)号：US20090306752A1
公开(公告)日：2009-12-10
申请号：US12541551
申请日：2009-08-14
申请人： Michael J. Ebert , John L. Sommer , Jordan D. Honeck , Richard D. Ries , Pedro A. Meregotte , Kenneth R. Brennen
发明人： Michael J. Ebert , John L. Sommer , Jordan D. Honeck , Richard D. Ries , Pedro A. Meregotte , Kenneth R. Brennen
IPC分类号： A61N1/05
CPC分类号： A61N1/056
摘要： An implantable medical device that includes a lead body extending from a proximal end to a distal end, a plurality of conductors extending between the proximal end and the distal end of the lead body, and an insulative layer formed of a hydrolytically stable polyimide material surrounding the plurality of conductors. In one embodiment, the hydrolytically stable polyimide material is an Si polyimide material.
摘要翻译：一种可植入医疗装置，其包括从近端延伸到远端的引线体，在所述引线体的近端和远端之间延伸的多根导体，以及由水解稳定的聚酰亚胺材料形成的绝缘层，多个导体。在一个实施方案中，水解稳定的聚酰亚胺材料是Si聚酰亚胺材料。

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