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1. 发明授权

US08903512B2 Medical system including a novel bipolar pacing pair 有权
标题翻译：医疗系统包括一个新颖的双极起搏对
公开(公告)号：US08903512B2
公开(公告)日：2014-12-02
申请号：US10630547
申请日：2003-07-29
申请人： Mark T. Marshall , Teresa A. Whitman , Eduardo N. Warman , Jeffrey M. Gillberg , Matthew D. Bonner , Mark L. Brown
发明人： Mark T. Marshall , Teresa A. Whitman , Eduardo N. Warman , Jeffrey M. Gillberg , Matthew D. Bonner , Mark L. Brown
IPC分类号： A61N1/05 , A61N1/368 , A61N1/37
CPC分类号： A61N1/057 , A61N1/0568 , A61N1/0573 , A61N1/368 , A61N1/3702 , A61N2001/0585
摘要： An implantable electrical medical system comprises a low voltage cathode electrode assembly, including a cathode surface adapted for, intimate contact with electrically active tissue, and a low voltage anode electrode assembly, including an anode surface and a porous layer extending over the anode surface. The cathode surface and the anode surface function as a bipolar pair for pacing and the porous layer extending over the anode surface allows conduction therethrough and prevents the anode surface from contacting the electrically active tissue in order to prevent anodal stimulation.
摘要翻译：可植入电气医疗系统包括低电压阴极电极组件，其包括适于与电活性组织紧密接触的阴极表面，以及包括在阳极表面上延伸的阳极表面和多孔层的低压阳极电极组件。阴极表面和阳极表面用作用于起搏的双极对，并且在阳极表面上延伸的多孔层允许通过其传导，并且防止阳极表面接触电活性组织以防止阳极刺激。

2. 发明申请

US20130197597A1 TECHNIQUES FOR MITIGATING MOTION ARTIFACTS FROM IMPLANTABLE PHYSIOLOGICAL SENSORS 有权
公开(公告)号：US20130197597A1
公开(公告)日：2013-08-01
申请号：US13360149
申请日：2012-01-27
申请人： David A. Anderson , Noah D. Barka , Erin D. Grassl , Matthew D. Bonner
发明人： David A. Anderson , Noah D. Barka , Erin D. Grassl , Matthew D. Bonner
IPC分类号： A61N1/365 , A61B5/02 , A61B5/08 , A61B5/053 , A61B5/1459 , A61B5/00 , A61B5/0402
CPC分类号： A61B5/0205 , A61B5/0006 , A61B5/026 , A61B5/0261 , A61B5/042 , A61B5/046 , A61B5/0538 , A61B5/11 , A61B5/1116 , A61B5/14552 , A61B5/6867 , A61B5/7207 , A61B7/003 , A61B7/023 , A61B7/04 , A61N1/3622 , A61N1/3627 , A61N1/36514 , A61N1/36521 , A61N1/36557 , A61N1/36571 , A61N1/36578 , A61N1/36585
摘要： Disclosed techniques include monitoring a physiological characteristic of a patient with a sensor that is mounted to an inner wall of a thoracic cavity of the patient, and sending a signal based on the monitored physiological characteristic from the sensor to a remote device.

3. 发明授权

US07711421B2 Method and system for vagal nerve stimulation with multi-site cardiac pacing 有权
标题翻译：多节点心脏起搏迷走神经刺激方法与系统
公开(公告)号：US07711421B2
公开(公告)日：2010-05-04
申请号：US11835808
申请日：2007-08-08
申请人： Lisa L. Shafer , Steve R. LaPorte , James R. Keogh , Michael R. S. Hill , Matthew D. Bonner
发明人： Lisa L. Shafer , Steve R. LaPorte , James R. Keogh , Michael R. S. Hill , Matthew D. Bonner
IPC分类号： A61N1/362
CPC分类号： A61N1/39 , A61N1/36114 , A61N1/362 , A61N1/3627 , A61N1/36514 , A61N1/3684 , A61N1/385 , A61N1/3956
摘要： A method of performing a medical procedure is provided. The medical procedure includes stimulation of a patient's heart while stimulating a nerve of the patient in order to modulate the patient's inflammatory process. More particularly, the medical procedure includes pacing the ventricles of the patient's heart while stimulating the vagal nerve of the patient. Systems and devices for performing the medical procedure are also provided.
摘要翻译：提供了一种执行医疗程序的方法。医疗过程包括刺激患者的心脏同时刺激患者的神经以调节患者的炎症过程。更具体地，医疗过程包括在刺激患者的迷走神经的同时起搏患者心脏的心室。还提供用于执行医疗程序的系统和设备。

4. 发明申请

US20080172012A1 INJECTION NEEDLE HAVING LATERAL DELIVERY PORTS AND METHOD FOR THE MANUFACTURE THEREOF 审中-公开
标题翻译：具有横向输送口的注射针及其制造方法
公开(公告)号：US20080172012A1
公开(公告)日：2008-07-17
申请号：US11555086
申请日：2006-10-31
申请人： Prasanga D. Hiniduma-Lokuge , Daniel C. Sigg , John L. Sommer , Matthew D. Bonner , Brian C.A. Fernandes
发明人： Prasanga D. Hiniduma-Lokuge , Daniel C. Sigg , John L. Sommer , Matthew D. Bonner , Brian C.A. Fernandes
IPC分类号： A61M5/32
CPC分类号： A61M5/3291 , A61M5/3286 , A61M25/00 , B21G1/08
摘要： An injection needle comprises an elongated body having an outer surface and an inner surface defining a longitudinal channel through the tubular body. The elongated body further comprises a distal end and at least one lateral delivery port extending from the inner surface to the outer surface proximate the distal end and fluidly coupled to the longitudinal channel. A distal tip is coupled to the distal end and comprises a radio-opaque material.
摘要翻译：注射针包括具有外表面和限定通过管状体的纵向通道的内表面的细长体。细长主体还包括远端和至少一个侧向输送端口，该至少一个侧向输送端口从内表面延伸到靠近远端的外表面并且流体地连接到纵向通道。远侧末端联接到远端并且包括不透射线材料。

5. 发明申请

US20080161843A1 Vessel support device and method of vessel harvesting 审中-公开
标题翻译：船舶支持装置和船舶采收方法
公开(公告)号：US20080161843A1
公开(公告)日：2008-07-03
申请号：US11974922
申请日：2007-10-16
申请人： Cynthia T. Clague , Michael J. Hobday , Raymond W. Usher , Roderick E. Briscoe , Katherine S. Olig , Ana R. Menk , Christopher P. Olig , Eric A. Meyer , Steven C. Christian , Thomas P. Daigle , Robert H. Reetz , Jeffrey D. Sandstrom , James R. Keogh , Matthew D. Bonner , Scott E. Jahns , Philip J. Haarstad
发明人： Cynthia T. Clague , Michael J. Hobday , Raymond W. Usher , Roderick E. Briscoe , Katherine S. Olig , Ana R. Menk , Christopher P. Olig , Eric A. Meyer , Steven C. Christian , Thomas P. Daigle , Robert H. Reetz , Jeffrey D. Sandstrom , James R. Keogh , Matthew D. Bonner , Scott E. Jahns , Philip J. Haarstad
IPC分类号： A61B17/32 , A61M5/00 , A61M31/00 , A61M5/178 , A61B19/00
CPC分类号： A61B17/32 , A61B17/00008 , A61B17/3205 , A61B17/32053 , A61B2017/320064
摘要： Embodiments of the invention provide a vessel support system and a method of vessel harvesting. The system can include a cutting device, a catheter adapted to be inserted into a section of the vessel in order to support the vessel as the cutting device is advanced over the vessel, and a cannula adapted to be coupled to the vessel and adapted to receive the catheter as the catheter is inserted into the section of the vessel. The method can include orienting a cutting device coaxially with the cannula and the catheter and advancing the cutting device over the cannula, the catheter, and the section of the vessel in order to core out the section of the vessel and a portion of the surrounding tissue.
摘要翻译：本发明的实施例提供了一种血管支持系统和血管收集方法。该系统可以包括切割装置，适于插入到容器的一部分中的导管，以便当切割装置前进在容器上时支撑容器，以及适于联接到容器并适于接收的套管作为导管的导管插入血管的部分。该方法可以包括将切割装置与套管和导管同轴定向，并将切割装置推进套管，导管和容器的部分，以便将血管的一部分和周围组织的一部分。

6. 发明申请

US20080161841A1 Cutting device and method of vessel harvesting 审中-公开
标题翻译：切割装置和采集方法
公开(公告)号：US20080161841A1
公开(公告)日：2008-07-03
申请号：US11974914
申请日：2007-10-16
申请人： Cynthia T. Clague , Michael J. Hobday , Raymond W. Usher , Roderick E. Briscoe , Katherine S. Olig , Ana R. Menk , Christopher P. Olig , Eric A. Meyer , Steven C. Christian , Thomas P. Daigle , Robert H. Reetz , Jeffrey D. Sandstrom , James R. Keogh , Matthew D. Bonner , Scott E. Jahns , Philip J. Haarstad
发明人： Cynthia T. Clague , Michael J. Hobday , Raymond W. Usher , Roderick E. Briscoe , Katherine S. Olig , Ana R. Menk , Christopher P. Olig , Eric A. Meyer , Steven C. Christian , Thomas P. Daigle , Robert H. Reetz , Jeffrey D. Sandstrom , James R. Keogh , Matthew D. Bonner , Scott E. Jahns , Philip J. Haarstad
IPC分类号： A61B17/3205
CPC分类号： A61B17/32 , A61B17/00008 , A61B17/3205 , A61B17/32053 , A61B2017/320064
摘要： Embodiments of the invention provide a cutting device and method of vessel harvesting. The cutting device can include at least one tubular member, a cutting element, and a centering member. The cutting device can include at least one tubular member with a flexible section and a cutting element. The method of vessel harvesting can include spacing a cutting element of the cutting device from the vessel as the cutting element is advanced over the vessel.
摘要翻译：本发明的实施例提供一种切割装置和容器收获方法。切割装置可以包括至少一个管状构件，切割元件和定心构件。切割装置可以包括具有柔性部分和切割元件的至少一个管状部件。当切割元件在容器上前进时，容器收集的方法可以包括将切割装置的切割元件与容器间隔开。

7. 发明授权

US07269457B2 Method and system for vagal nerve stimulation with multi-site cardiac pacing 失效
标题翻译：多节点心脏起搏迷走神经刺激方法与系统
公开(公告)号：US07269457B2
公开(公告)日：2007-09-11
申请号：US10737493
申请日：2003-12-16
申请人： Lisa L. Shafer , Steve R. LaPorte , James R. Keogh , Michael R. S. Hill , Matthew D. Bonner
发明人： Lisa L. Shafer , Steve R. LaPorte , James R. Keogh , Michael R. S. Hill , Matthew D. Bonner
IPC分类号： A61N1/362
CPC分类号： A61N1/39 , A61N1/36114 , A61N1/362 , A61N1/3627 , A61N1/36514 , A61N1/3684 , A61N1/385 , A61N1/3956
摘要： A method of performing a medical procedure is provided. The medical procedure includes stimulation of a patient's heart while stimulating a nerve of the patient in order to modulate the patient's inflammatory process. More particularly, the medical procedure includes pacing the ventricles of the patient's heart while stimulating the vagal nerve of the patient. Systems and devices for performing the medical procedure are also provided.
摘要翻译：提供了一种执行医疗程序的方法。医疗过程包括刺激患者的心脏同时刺激患者的神经以调节患者的炎症过程。更具体地，医疗过程包括在刺激患者的迷走神经的同时起搏患者心脏的心室。还提供用于执行医疗程序的系统和设备。

8. 发明授权

US06837848B2 Methods and apparatus for accessing and stabilizing an area of the heart 有权
公开(公告)号：US06837848B2
公开(公告)日：2005-01-04
申请号：US10342932
申请日：2003-01-15
申请人： Matthew D. Bonner , Paul A. Pignato , Scott E. Jahns , Raymond W. Usher
发明人： Matthew D. Bonner , Paul A. Pignato , Scott E. Jahns , Raymond W. Usher
IPC分类号： A61B18/14 , A61B19/00 , A61B19/02 , A61B19/08 , A61B19/10 , A61M1/00 , A61B1/00
CPC分类号： A61B18/1485 , A61B18/1402 , A61B46/00 , A61B46/23 , A61B50/20 , A61B2018/00291 , A61B2090/306 , A61B2090/3614 , A61B2218/007 , A61M1/008
摘要： A tubular suction tool for accessing an anatomic surface or anatomic space and particularly the pericardium to access pericardial space and the epicardial surface of the heart to implant cardiac leads in a minimally invasive manner are disclosed. The suction tool incorporates a suction pad concave wall defining a suction cavity, a plurality of suction ports arrayed about the concave wall, and a suction lumen, to form a bleb of tissue into the suction cavity when suction is applied. The suction cavity extends along one side of the suction pad, so that the suction pad and suction cavity can be applied tangentially against a tissue site. The suction tool can incorporate light emission and video imaging of tissue adjacent the suction pad. A working lumen terminating in a working lumen port into the suction cavity enables introduction of tools, cardiac leads, and other instruments, cells, drugs or materials into or through the tissue bleb drawn into the suction cavity.

9. 发明授权

US06647291B1 Method and apparatus for cardiac defibrillation 有权
标题翻译：用于心脏除颤的方法和装置
公开(公告)号：US06647291B1
公开(公告)日：2003-11-11
申请号：US09540136
申请日：2000-03-31
申请人： Matthew D. Bonner , Rahul Mehra
发明人： Matthew D. Bonner , Rahul Mehra
IPC分类号： A61N118
CPC分类号： A61N1/0563 , A61N2001/0585
摘要： A method for cardioverting or defibrillating a human heart, performed by placing a transvenous lead having a cardioversion or defibrillation electrode such that the electrode is located at least partially within the middle cardiac vein of a patient's heart and placing an additional cardioversion or defibrillation electrode in the superior vena cava of the patient's heart and thereafter delivering a cardioversion or defibrillation pulse between the first and second electrodes. The method may be practiced by placing the transvenous such that the defibrillation electrode it carries extends around the apex of the patient's heart, and the transvenous lead may be advanced through one cardiac vein toward the apex of the patient's heart and thereafter advanced upward through a different cardiac vein.
摘要翻译：通过放置具有心脏复律或除颤电极的经静脉导管使得电极至少部分位于患者心脏的中心静脉内并将另外的心脏复律或除颤电极放置在心脏复律或除颤电极中来进行心脏转复或除纤维化的方法患者心脏的上腔静脉，然后在第一和第二电极之间递送心脏复律或除颤脉冲。该方法可以通过放置静脉使得其携带的除颤电极围绕患者心脏的顶点延伸，并且经静脉导管可以通过一个心静脉前进到患者心脏的顶点，然后向上通过不同的心脏静脉

10. 发明授权

US06379346B1 Introducer system 有权
标题翻译：介绍系统
公开(公告)号：US06379346B1
公开(公告)日：2002-04-30
申请号：US09552250
申请日：2000-04-18
申请人： Michael E. McIvor , Kenneth C. Gardeski , Pedro A. Meregotte , Matthew D. Bonner , Timothy G. Laske , Linda L. Lach
发明人： Michael E. McIvor , Kenneth C. Gardeski , Pedro A. Meregotte , Matthew D. Bonner , Timothy G. Laske , Linda L. Lach
IPC分类号： A61M2500
CPC分类号： A61M25/0668 , A61M25/01 , A61M2025/0675
摘要： An introducer is structured with an elongated tube having first and second lumens. A molded handle is coupled to the proximal end of the tube with an opening aligned with the first lumen. Further, a wall adjacent the opening of the handle defines a slot and is located diametrically opposite the second lumen. A tubular reinforcement member is located within the second lumen and the handle is provided with a second opening, thereby having a communication with the second lumen. In another embodiment a lead/catheter introducer includes an implantable lead or catheter having an elongated first lumen through which the lead or catheter passes and a second lumen extends parallel to the first lumen along at least a distal portion thereof. A tubular reinforcement member is disposed within the second lumen. The tubular reinforcement member further includes an internal lumen and a curvable stylet disposed in the lumen.
摘要翻译：导引器构造有具有第一和第二腔的细长管。模制手柄与管的近端连接，开口与第一内腔对准。此外，与手柄的开口相邻的壁限定了狭槽，并且位于与第二内腔完全相对的位置。管状加强构件位于第二内腔内，手柄设置有第二开口，从而与第二腔相连通。在另一个实施例中，引导/导管导引器包括具有细长的第一内腔的可植入引线或导管，所述引导件或导管通过所述细长的第一内腔，并且沿其至少其远端部分平行于所述第一内腔延伸的第二腔。管状加强构件设置在第二内腔内。管状加强构件还包括内腔和设置在内腔中的可调节探针。

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