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1. 发明授权

US06379346B1 Introducer system 有权
标题翻译：介绍系统
公开(公告)号：US06379346B1
公开(公告)日：2002-04-30
申请号：US09552250
申请日：2000-04-18
申请人： Michael E. McIvor , Kenneth C. Gardeski , Pedro A. Meregotte , Matthew D. Bonner , Timothy G. Laske , Linda L. Lach
发明人： Michael E. McIvor , Kenneth C. Gardeski , Pedro A. Meregotte , Matthew D. Bonner , Timothy G. Laske , Linda L. Lach
IPC分类号： A61M2500
CPC分类号： A61M25/0668 , A61M25/01 , A61M2025/0675
摘要： An introducer is structured with an elongated tube having first and second lumens. A molded handle is coupled to the proximal end of the tube with an opening aligned with the first lumen. Further, a wall adjacent the opening of the handle defines a slot and is located diametrically opposite the second lumen. A tubular reinforcement member is located within the second lumen and the handle is provided with a second opening, thereby having a communication with the second lumen. In another embodiment a lead/catheter introducer includes an implantable lead or catheter having an elongated first lumen through which the lead or catheter passes and a second lumen extends parallel to the first lumen along at least a distal portion thereof. A tubular reinforcement member is disposed within the second lumen. The tubular reinforcement member further includes an internal lumen and a curvable stylet disposed in the lumen.
摘要翻译：导引器构造有具有第一和第二腔的细长管。模制手柄与管的近端连接，开口与第一内腔对准。此外，与手柄的开口相邻的壁限定了狭槽，并且位于与第二内腔完全相对的位置。管状加强构件位于第二内腔内，手柄设置有第二开口，从而与第二腔相连通。在另一个实施例中，引导/导管导引器包括具有细长的第一内腔的可植入引线或导管，所述引导件或导管通过所述细长的第一内腔，并且沿其至少其远端部分平行于所述第一内腔延伸的第二腔。管状加强构件设置在第二内腔内。管状加强构件还包括内腔和设置在内腔中的可调节探针。

2. 发明授权

US06280433B1 Introducer system 有权
标题翻译：介绍系统
公开(公告)号：US06280433B1
公开(公告)日：2001-08-28
申请号：US09392715
申请日：1999-09-09
申请人： Michael E. McIvor , Kenneth C. Gardeski , Pedro A. Meregotte , Mathew D. Bonner , Timothy G. Laske , Linda L. Lach
发明人： Michael E. McIvor , Kenneth C. Gardeski , Pedro A. Meregotte , Mathew D. Bonner , Timothy G. Laske , Linda L. Lach
IPC分类号： A61M2500
CPC分类号： A61M25/0668 , A61M25/01 , A61M2025/0675
摘要： An introducer or guide catheter for directing an implantable medical device such as a lead or catheter to a desired location within a patient's body. In one embodiment of the invention, the introducer comprises a two-lumen tube. A first lumen is configured to receive the implantable medical device that is to be introduced. A second lumen is provided to receive an insertable, elongated guiding member such as a stylet, which may be shapable in various orientations, and which may be used to alter the configuration of the introducer. The second lumen may be provided with an internal coil or other tubular reinforcement member to prevent perforation of this lumen by the guiding member when the introducer is in the patient's body. In order to facilitate removal of the introducer over an implantable medical device having a connector or fitting that is larger than the internal diameter of the first lumen, the introducer may be adapted to be slit or split along its length. In some embodiments of the invention, the introducer may be rendered splittable by provision of a weakened zone along its length. According to yet another aspect of the invention, the introducer may be provided with a luer lock at its proximal end to facilitate connection of the introducer to a hemostasis valve, t-fitting, or the like.
摘要翻译：导引器或引导导管，用于将诸如引线或导管的可植入医疗装置引导到患者体内的期望位置。在本发明的一个实施例中，导引器包括两腔管。第一管腔被配置为接收待引入的可植入医疗装置。提供第二内腔以接收可插入的细长引导构件，例如探针，其可以以各种取向成形，并且其可以用于改变导引器的构造。第二内腔可以设置有内部线圈或其他管状加强构件，以在导引器位于患者体内时防止引导构件对该内腔穿孔。为了便于在具有大于第一内腔的内径的连接器或配件的可植入医疗装置上移除导引器，导引器可以适于沿着其长度被切割或分开。在本发明的一些实施例中，导引器可以通过沿着其长度提供弱化区域而被分解。根据本发明的另一方面，导引器在其近端可以设置有鲁尔锁，以便于将导引器连接到止血阀，t形配件等。

3. 发明授权

US5928277A One piece defibrillation lead circuit 失效
标题翻译：一片除颤引线电路
公开(公告)号：US5928277A
公开(公告)日：1999-07-27
申请号：US26064
申请日：1998-02-19
申请人： Timothy G. Laske , David W. Mayer , Pedro A. Meregotte , Bret R. Shoberg , Gregory A. Boser
发明人： Timothy G. Laske , David W. Mayer , Pedro A. Meregotte , Bret R. Shoberg , Gregory A. Boser
IPC分类号： A61N1/05
CPC分类号： A61N1/0563
摘要： An implantable electrical lead having a lead body with a longitudinal lumen therein and a stranded electrical conductor located in the lumen and which exits the lumen at a distal portion of the lead body, the distal end of the conductor being curved to form a loop and reentering the lumen, terminating within the lumen alongside a more proximal portion of the conductor. The portion of the conductor exterior to the lumen is wound around the lead body to form a coiled electrode. In some embodiments the distal end of the conductor is coupled to a more proximal portion of the conductor to form a loop and the loop is wound around the lead body to form a bifilar coil. In other embodiments the conductor is wound around the lead body to form a mono-filar coil. The distal end of the conductor is mechanically and electrically coupled to a more proximal portion of the conductor, within the lumen.
摘要翻译：一种植入式电引线，其具有其中具有纵向内腔的引线主体和位于所述内腔中的绞合电导体，并且在所述引线主体的远端部分处离开所述内腔，所述导体的远端弯曲以形成环并重新进入该管腔与导管的较近端部分一起终止于管腔内。导管外部的导体部分缠绕在引线体上以形成线圈电极。在一些实施例中，导体的远端耦合到导体的更近端部分以形成环，并且环绕引线体缠绕以形成双线圈。在其它实施例中，导体缠绕在引线体上以形成单丝线圈。导体的远端在管腔内机械地和电耦合到导体的更靠近的部分。

4. 发明授权

US5807399A Method for removal of chronically implanted leads and leads optimized for use therewith 失效
标题翻译：用于去除长期植入的引线和优化用于其的引线的方法
公开(公告)号：US5807399A
公开(公告)日：1998-09-15
申请号：US736000
申请日：1996-10-23
申请人： Timothy G. Laske , Pedro A. Meregotte , Michael R. Dollimer
发明人： Timothy G. Laske , Pedro A. Meregotte , Michael R. Dollimer
IPC分类号： A61N1/05
CPC分类号： A61N1/057 , A61N2001/0578
摘要： A method of removing chronically implanted pacing leads and leads specifically adapted to be removed using the method. The leads are constructed so that upon tension applied to the electrode, it is withdrawn to a first location, so that upon further application of tension, the sheath located distal to the withdrawn electrode may collapse, enhancing its removability. In some embodiments of leads particularly adapted for use in conjunction with the method, the leads are provided with a mechanism for allowing breakage of the lead adjacent the points to which the electrode has been withdrawn, upon application of further tension to the electrode.
摘要翻译：使用该方法去除长期植入的起搏引线和引线的方法，其特别适于被去除。引线被构造成使得当施加到电极的张力时，其被拉出到第一位置，使得在进一步施加张力时，位于引出电极的远侧的护套可能会塌陷，从而增强其可移除性。在特别适合于与该方法一起使用的引线的一些实施例中，引线设置有用于在向电极施加进一步的张力时允许引线邻近电极已被取出的点断裂的机构。

5. 发明授权

US5676694A Medical electrical lead 失效
标题翻译：医用电线
公开(公告)号：US5676694A
公开(公告)日：1997-10-14
申请号：US657577
申请日：1996-06-07
申请人： Gregory A. Boser , Mark A. Hjelle , Timothy G. Laske , Mark Mabel , Pedro A. Meregotte , Jon M. Ocel , Clare E. Padgett , David G. Schaenzer , Bret R. Shoberg , Sandra F. Viktora
发明人： Gregory A. Boser , Mark A. Hjelle , Timothy G. Laske , Mark Mabel , Pedro A. Meregotte , Jon M. Ocel , Clare E. Padgett , David G. Schaenzer , Bret R. Shoberg , Sandra F. Viktora
IPC分类号： A61N1/05 , A61B5/042
CPC分类号： A61N1/0563
摘要： A medical electrical lead having an elongated lead body provided with an internal longitudinally extending lumen carrying an elongated stranded or cabled conductor and an electrode coil, located on said lead body. The coil is coupled to the conductor by a conductive sleeve having a tubular portion which has an internal lumen through which the conductor passes and a groove or bore which engages only a portion of a turn or turns of the electrode coil, such that the coil is oriented generally perpendicular to the internal lumen of said sleeve and to the conductor.
摘要翻译：一种具有细长引线主体的医用电引线，该引线体设置有位于所述引线主体上的内部纵向延伸的内腔，其承载细长绞合或电缆导体和电极线圈。线圈通过具有管状部分的导电套管耦合到导体，该管状部分具有导体所穿过的内腔，以及仅与电极线圈的匝或匝相接合的凹槽或孔，使得线圈为定向为大致垂直于所述套筒的内腔和导体。

6. 发明授权

US06939338B2 Methods and apparatus for imparting curves in elongated medical catheters 失效
标题翻译：在细长的医用导管中赋予曲线的方法和装置
公开(公告)号：US06939338B2
公开(公告)日：2005-09-06
申请号：US10125365
申请日：2002-04-19
申请人： Steven L. Waldhauser , Timothy G. Laske , James F. Kelley , Kenneth C. Gardeski , Gregory P. Shipe
发明人： Steven L. Waldhauser , Timothy G. Laske , James F. Kelley , Kenneth C. Gardeski , Gregory P. Shipe
IPC分类号： A61B1/005 , A61M25/00 , A61M25/01 , A61M25/092
CPC分类号： A61M25/0158 , A61B1/0058 , A61M25/0041 , A61M25/0054 , A61M2025/0064
摘要： Curves and dynamic shapes are imparted in distal segments of medical instruments e.g., catheters, through use of a temperature-activated actuator coupled to distal segment of the instrument body. The actuator comprises includes members extending side-by-side in substantially a common plane and configured to move in opposite directions when independently activated. A first heating device is coupled to a first actuator member and configured to deliver thermal energy to the first actuator member to activate the first actuator member and cause the first actuator member to move the distal segment in a first direction. A second heating device is coupled to a second actuator member and configured to deliver thermal energy to the second actuator member to activate the second actuator member and cause the second actuator member to move the distal segment in a second direction opposed to the first direction.
摘要翻译：曲线和动态形状通过使用耦合到仪器主体的远端部分的温度激活的致动器，在医疗器械的远端部分（例如导管）中被施加。致动器包括在基本上共同的平面中并排延伸的构件，并且构造成当独立地启动时沿相反的方向移动。第一加热装置联接到第一致动器构件并且构造成将热能传递到第一致动器构件以启动第一致动器构件并使第一致动器构件沿第一方向移动远侧段。第二加热装置联接到第二致动器构件并且被配置为将热能传递到第二致动器构件以致动第二致动器构件并使第二致动器构件沿与第一方向相反的第二方向移动远侧段。

7. 发明授权

US06213988B1 Introducer with external hemostasis clip 失效
标题翻译：介绍与外部止血夹
公开(公告)号：US06213988B1
公开(公告)日：2001-04-10
申请号：US09021558
申请日：1998-02-10
申请人： Michael E. McIvor , Mary M. Morris , Judith Betz , Timothy G. Laske
发明人： Michael E. McIvor , Mary M. Morris , Judith Betz , Timothy G. Laske
IPC分类号： A61M500
CPC分类号： A61M25/0662 , A61M25/01
摘要： An introducer of the type employing an elongated introducer sleeve for receiving a catheter or lead body and an associated hemostasis clamp including a clamping member configured to engage the outer circumference of the introducer sleeve. The clamp is provided with a mechanism for maintaining the clamping member in engagement with said outer circumference of the sleeve to compress the outer circumference of the sleeve around a catheter or lead body inserted therethrough. In some embodiments the clamp takes the form of a hinged clamp provided with two jaws each having a recess adapted to engage a portion of the other circumference of the introducer sleeve. In other embodiments the clamp takes the form of interacting ramped members. The clamp is maintained in engagement with the sleeve either resiliently or by means of a latch.
摘要翻译：一种引入器，其采用细长导引器套筒，用于接纳导管或引线体，以及相关联的止血钳，其包括构造成接合引导器套筒的外圆周的夹紧构件。夹具设置有用于将夹紧构件保持与套筒的外周接合的机构，以将套筒的外周压缩成插入其中的导管或引线体。在一些实施例中，夹具采取铰链夹具的形式，其设置有两个钳口，每个钳口具有适于接合导引套筒的另一个圆周的一部分的凹部。在其他实施例中，夹具采取相互作用的倾斜构件的形式。夹具可以弹性地或通过闩锁保持与套筒接合。

8. 发明授权

US06185464B2 Arrangement for planting an endocardial cardiac lead 失效
标题翻译：种植心内膜心脏铅的安排
公开(公告)号：US06185464B2
公开(公告)日：2001-02-06
申请号：US09262387
申请日：1999-03-04
申请人： Matthew D. Bonner , Timothy G. Laske
发明人： Matthew D. Bonner , Timothy G. Laske
IPC分类号： A61N100
CPC分类号： A61N1/056 , A61M25/0043 , A61M25/01 , A61N2001/0578
摘要： An arrangement for introducing and implanting the electrode(s) of an endocardial implantable cardiac lead at a cardiac implantation site within a heart chamber or vessel. An elongated guide body formed of flexible material and extending between a guide body proximal end and a guide body distal end is advanced transvenously to position the guide body distal end in relation to the cardiac implantation site. A guide body tracking mechanism is coupled with the lead distal end for receiving and slidingly engaging the guide body to allow the cardiac lead to be advanced along the guide body until the electrode is positioned at the cardiac implantation site. A pusher mechanism formed of an elongated pusher body of flexible material extends between a pusher body proximal end and a pusher body distal end and has a cardiac lead engaging mechanism for engaging the cardiac lead at or adjacent the distal lead end. The pusher body has sufficient column strength to be advanced alongside the guide body and lead body with the cardiac lead engaging mechanism engaging and slidingly advancing the guide body tracking mechanism and the cardiac lead distally along the guide body to thereby allow the cardiac lead to be advanced along the guide body until the electrode is positioned at the cardiac implantation site. The lead body is released from the lead engaging mechanism and fixed, if the lead includes a fixation mechanism. The pusher mechanism is retracted by retraction of the pusher body.
摘要翻译：用于在心室或血管内的心脏植入部位处引入和植入心内可植入心脏引线的电极的装置。由柔性材料形成并在引导体近端和引导体远端之间延伸的细长引导体相对于心脏植入部位传递推进以引导体远端。引导体跟踪机构与引线远端联接，用于接收和滑动地接合引导体，以允许心脏引线沿引导体前进，直到电极定位在心脏植入部位。由细长的柔性材料推动器构成的推动机构在推动体本体近端和推动体本体远端之间延伸，并且具有心脏引线接合机构，用于在远侧引线端处或与其相邻的心脏引线接合。推动器主体具有足够的柱强度，使引导体和引线体沿着引导体接合并使引导体跟踪机构和心引导体沿引导体向远侧滑动地前进，从而允许心导线前进沿着引导体直到电极位于心脏植入部位。如果引线包括固定机构，则引线体从引线接合机构释放并固定。推动器机构通过推动器主体的缩回缩回。

9. 发明授权

US5728149A Integral spiral band electrode for transvenous defibrillation leads 失效
标题翻译：用于经静脉除颤导联的整体螺旋带电极
公开(公告)号：US5728149A
公开(公告)日：1998-03-17
申请号：US580006
申请日：1995-12-20
申请人： Timothy G. Laske , Matthew D. Bonner , Jon M. Ocel
发明人： Timothy G. Laske , Matthew D. Bonner , Jon M. Ocel
IPC分类号： A61N1/05 , A61B5/04
CPC分类号： A61N1/056
摘要： A cardioversion/defibrillation lead, and method of manufacture thereof, for location in a human heart. An elongated lead body having an insulating outer sheath extends between proximal and distal ends thereof, and an elongated defibrillation conductor within the lead body extends from a connector at the proximal end to a distal end at a predetermined location along the lead body length. A spiral band defibrillation electrode extends in spiral turns around the exterior of the insulating outer sheath for a pre-determined defibrillation electrode length. The defibrillation electrode is fabricated of a single tube of body compatible, electrically conductive material having first and second tube ends and an inside diameter selected to fit over the outer sheath and the internally disposed defibrillation lead conductor. At least one (and preferably a plurality) spiral slit is formed therein extending from first and second slit end points, spaced from the first and second ends, respectively, thereby forming at least one spiral band integrally attached to first and second end bands, respectively. At least one of the first and second end bands is attached to the defibrillation lead conductor at or near the distal end thereof. In other embodiments, intermediate connection bands are formed along the length of the spiral band, and electrical connections are made between such intermediate connection bands and the defibrillation lead conductor.
摘要翻译：心脏复律/除颤引线及其制造方法，用于在人心脏中定位。具有绝缘外护套的细长引线主体在其近端和远端之间延伸，并且引线主体内的细长除颤导体沿着引线本体长度从近端处的连接器延伸到预定位置处的远端。螺旋带除颤电极围绕绝缘外护套的外部螺旋形旋转，以预定的除颤电极长度。除颤电极由具有第一和第二管端的单体体相容的导电材料制成，并且内径选择为配合在外护套和内部设置的除颤引线导体上。至少一个（并且优选多个）螺旋狭缝形成在其中，从第一和第二狭缝端点分别与第一和第二端分开延伸，从而分别形成至少一个与第一和第二端带整体连接的螺旋带。第一和第二端带中的至少一个在其远端处或附近附接到除颤引线导体。在其他实施例中，沿着螺旋带的长度形成中间连接带，并且在这种中间连接带和除颤引线导体之间形成电连接。

10. 发明授权

US06868291B1 Arrangement for implanting an endocardial cardiac lead 有权
标题翻译：用于植入心内膜心脏铅的装置
公开(公告)号：US06868291B1
公开(公告)日：2005-03-15
申请号：US09699865
申请日：2000-10-30
申请人： Matthew D. Bonner , Timothy G. Laske
发明人： Matthew D. Bonner , Timothy G. Laske
IPC分类号： A61N1/05
CPC分类号： A61N1/056 , A61M25/0043 , A61M25/01 , A61N2001/0578
摘要： An arrangement for introducing and implanting the electrode(s) of an endocardial implantable cardiac lead at a cardiac implantation site within a heart chamber or vessel. An elongated guide body formed of flexible material and extending between a guide body proximal end and a guide body distal end is advanced transvenously to position the guide body distal end in relation to the cardiac implantation site. Guide body tracking means is coupled with the lead distal end for receiving and slidingly engaging the guide body to allow the cardiac lead to be advanced along the guide body until the electrode is positioned at the cardiac implantation site. Pusher means formed of an elongated pusher body of flexible material extends between a pusher body proximal end and a pusher body distal end and has a cardiac lead engaging means for engaging the cardiac lead at or adjacent the distal lead end. The pusher body has sufficient column strength to be advanced alongside the guide body and lead body with the cardiac lead engaging means engaging and slidingly advancing the guide body tracking means and the cardiac lead distally along the guide body to thereby allow the cardiac lead to be advanced along the guide body until the electrode is positioned at the cardiac implantation site. The lead body is released from the lead engaging means and fixed, if the lead includes a fixation mechanism. The pusher means is retracted by retraction of the pusher body.
摘要翻译：用于在心室或血管内的心脏植入部位处引入和植入心内可植入心脏引线的电极的装置。由柔性材料形成并在引导体近端和引导体远端之间延伸的细长引导体相对于心脏植入部位传递推进以引导体远端。引导体跟踪装置与引线远端联接，用于接收和滑动地接合引导体，以允许心脏引导沿引导体前进，直到电极定位在心脏植入部位。由细长的柔性材料推动器构成的推动器装置在推动器本体近端和推动器主体远端之间延伸，并且具有心脏引线接合装置，用于在远侧引线端处或与其相邻的心脏引线接合。推动器主体具有足够的柱强度，以使引导体和引线体沿着引导体接合装置前进，引导体跟踪装置和心引导件沿引导体向远侧滑动，从而允许心导线前进沿着引导体直到电极位于心脏植入部位。如果引线包括固定机构，则引线体从引线接合装置释放并固定。推动器装置通过推动器主体的缩回缩回。

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