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1. 发明授权

US06379346B1 Introducer system 有权
标题翻译：介绍系统
公开(公告)号：US06379346B1
公开(公告)日：2002-04-30
申请号：US09552250
申请日：2000-04-18
申请人： Michael E. McIvor , Kenneth C. Gardeski , Pedro A. Meregotte , Matthew D. Bonner , Timothy G. Laske , Linda L. Lach
发明人： Michael E. McIvor , Kenneth C. Gardeski , Pedro A. Meregotte , Matthew D. Bonner , Timothy G. Laske , Linda L. Lach
IPC分类号： A61M2500
CPC分类号： A61M25/0668 , A61M25/01 , A61M2025/0675
摘要： An introducer is structured with an elongated tube having first and second lumens. A molded handle is coupled to the proximal end of the tube with an opening aligned with the first lumen. Further, a wall adjacent the opening of the handle defines a slot and is located diametrically opposite the second lumen. A tubular reinforcement member is located within the second lumen and the handle is provided with a second opening, thereby having a communication with the second lumen. In another embodiment a lead/catheter introducer includes an implantable lead or catheter having an elongated first lumen through which the lead or catheter passes and a second lumen extends parallel to the first lumen along at least a distal portion thereof. A tubular reinforcement member is disposed within the second lumen. The tubular reinforcement member further includes an internal lumen and a curvable stylet disposed in the lumen.
摘要翻译：导引器构造有具有第一和第二腔的细长管。模制手柄与管的近端连接，开口与第一内腔对准。此外，与手柄的开口相邻的壁限定了狭槽，并且位于与第二内腔完全相对的位置。管状加强构件位于第二内腔内，手柄设置有第二开口，从而与第二腔相连通。在另一个实施例中，引导/导管导引器包括具有细长的第一内腔的可植入引线或导管，所述引导件或导管通过所述细长的第一内腔，并且沿其至少其远端部分平行于所述第一内腔延伸的第二腔。管状加强构件设置在第二内腔内。管状加强构件还包括内腔和设置在内腔中的可调节探针。

2. 发明授权

US06868291B1 Arrangement for implanting an endocardial cardiac lead 有权
标题翻译：用于植入心内膜心脏铅的装置
公开(公告)号：US06868291B1
公开(公告)日：2005-03-15
申请号：US09699865
申请日：2000-10-30
申请人： Matthew D. Bonner , Timothy G. Laske
发明人： Matthew D. Bonner , Timothy G. Laske
IPC分类号： A61N1/05
CPC分类号： A61N1/056 , A61M25/0043 , A61M25/01 , A61N2001/0578
摘要： An arrangement for introducing and implanting the electrode(s) of an endocardial implantable cardiac lead at a cardiac implantation site within a heart chamber or vessel. An elongated guide body formed of flexible material and extending between a guide body proximal end and a guide body distal end is advanced transvenously to position the guide body distal end in relation to the cardiac implantation site. Guide body tracking means is coupled with the lead distal end for receiving and slidingly engaging the guide body to allow the cardiac lead to be advanced along the guide body until the electrode is positioned at the cardiac implantation site. Pusher means formed of an elongated pusher body of flexible material extends between a pusher body proximal end and a pusher body distal end and has a cardiac lead engaging means for engaging the cardiac lead at or adjacent the distal lead end. The pusher body has sufficient column strength to be advanced alongside the guide body and lead body with the cardiac lead engaging means engaging and slidingly advancing the guide body tracking means and the cardiac lead distally along the guide body to thereby allow the cardiac lead to be advanced along the guide body until the electrode is positioned at the cardiac implantation site. The lead body is released from the lead engaging means and fixed, if the lead includes a fixation mechanism. The pusher means is retracted by retraction of the pusher body.
摘要翻译：用于在心室或血管内的心脏植入部位处引入和植入心内可植入心脏引线的电极的装置。由柔性材料形成并在引导体近端和引导体远端之间延伸的细长引导体相对于心脏植入部位传递推进以引导体远端。引导体跟踪装置与引线远端联接，用于接收和滑动地接合引导体，以允许心脏引导沿引导体前进，直到电极定位在心脏植入部位。由细长的柔性材料推动器构成的推动器装置在推动器本体近端和推动器主体远端之间延伸，并且具有心脏引线接合装置，用于在远侧引线端处或与其相邻的心脏引线接合。推动器主体具有足够的柱强度，以使引导体和引线体沿着引导体接合装置前进，引导体跟踪装置和心引导件沿引导体向远侧滑动，从而允许心导线前进沿着引导体直到电极位于心脏植入部位。如果引线包括固定机构，则引线体从引线接合装置释放并固定。推动器装置通过推动器主体的缩回缩回。

3. 发明授权

US07184839B2 Catheter-delivered cardiac lead 有权
标题翻译：导管心脏导联
公开(公告)号：US07184839B2
公开(公告)日：2007-02-27
申请号：US10318518
申请日：2002-12-16
申请人： Willim J. Clemens , Michael L. Freiborg , Michael A. Ruff , Douglas N. Hess , Elisabeth L. Belden , Terrell M. Williams , Brian T. McHenry , Mark B. Bucheger , Timothy G. Laske , Matthew D. Bonner
发明人： Willim J. Clemens , Michael L. Freiborg , Michael A. Ruff , Douglas N. Hess , Elisabeth L. Belden , Terrell M. Williams , Brian T. McHenry , Mark B. Bucheger , Timothy G. Laske , Matthew D. Bonner
IPC分类号： A61N1/05
CPC分类号： A61N1/056 , A61N2001/058
摘要： A lead for delivering electrical signals to and/or receive electrical signals from a human heart that includes a solid inner conductor, and a fixation device having a titanium nitride coated surface and electrically coupled to the inner conductor. A steroid is applied to the titanium nitride surface of the fixation device, and at least one layer of insulation is positioned around the inner conductor. A conductive coil is positioned around and is insulated from the inner conductor, an electrode ring electrically coupled to the conductive coil is positioned around and is electrically isolated from the inner conductor, and an insulating spacer is positioned between and electrically isolates the ring electrode and the fixation device.
摘要翻译：用于将电信号传递到和/或接收来自包括实心内导体的人心脏的电信号的引线，以及具有氮化钛涂覆表面并电耦合到内导体的固定装置。将类固醇施加到固定装置的氮化钛表面，并且至少一层绝缘体围绕内部导体定位。导电线圈定位在内导体周围并与内导体绝缘，电耦合到导电线圈的电极环位于内导体周围并与内导体电隔离，并且绝缘间隔物位于电极之间并电隔离环电极和固定装置

4. 发明授权

US5902331A Arrangement for implanting an endocardial cardiac lead 失效
标题翻译：用于植入心内膜心脏铅的装置
公开(公告)号：US5902331A
公开(公告)日：1999-05-11
申请号：US037654
申请日：1998-03-10
申请人： Matthew D. Bonner , Timothy G. Laske
发明人： Matthew D. Bonner , Timothy G. Laske
IPC分类号： A61N1/05 , A61M25/01
CPC分类号： A61N1/056 , A61M25/0043 , A61M25/01 , A61N2001/0578
摘要： An arrangement for introducing and implanting the electrode(s) of an endocardial implantable cardiac lead at a cardiac implantation site within a heart chamber or vessel. An elongated guide body formed of flexible material and extending between a guide body proximal end and a guide body distal end is advanced transvenously to position the guide body distal end in relation to the cardiac implantation site. A guide body tracking mechanism is coupled with the lead distal end for receiving and slidingly engaging the guide body to allow the cardiac lead to be advanced along the guide body until the electrode is positioned at the cardiac implantation site. Pusher mechanism formed of an elongated pusher body of flexible material extends between a pusher body proximal end and a pusher body distal end and has a cardiac lead engaging mechanism for engaging the cardiac lead at or adjacent the distal lead end. The pusher body has sufficient column strength to be advanced alongside the guide body and lead body with the cardiac lead engaging mechanism engaging and slidingly advancing the guide body tracking mechanism and the cardiac lead distally along the guide body to thereby allow the cardiac lead to be advanced along the guide body until the electrode is positioned at the cardiac implantation site. The lead body is released from the lead engaging mechanism and fixed, if the lead includes a fixation mechanism. The pusher mechanism is retracted by retraction of the pusher body.
摘要翻译：用于在心室或血管内的心脏植入部位处引入和植入心内可植入心脏引线的电极的装置。由柔性材料形成并在引导体近端和引导体远端之间延伸的细长引导体相对于心脏植入部位传递推进以引导体远端。引导体跟踪机构与引线远端联接，用于接收和滑动地接合引导体，以允许心脏引线沿引导体前进，直到电极定位在心脏植入部位。由细长的柔性材料推动器主体构成的推动机构在推动体本体近端和推动器主体远端之间延伸，并且具有心脏引导接合机构，用于在远侧引线端处或与其相邻的心脏引线接合。推动器主体具有足够的柱强度，使引导体和引线体沿着引导体接合并使引导体跟踪机构和心引导体沿引导体向远侧滑动地前进，从而允许心导线前进沿着引导体直到电极位于心脏植入部位。如果引线包括固定机构，则引线体从引线接合机构释放并固定。推动器机构通过推动器主体的缩回缩回。

5. 发明授权

US5957970A Method of fabricating a medical electrical lead 失效
标题翻译：制造医用电线的方法
公开(公告)号：US5957970A
公开(公告)日：1999-09-28
申请号：US25485
申请日：1998-02-18
申请人： Bret R. Shoberg , Matthew D. Bonner , Timothy G. Laske
发明人： Bret R. Shoberg , Matthew D. Bonner , Timothy G. Laske
IPC分类号： A61N1/05
CPC分类号： A61N1/056 , A61N1/0563
摘要： A method of producing a lead which is isodiametric or nearly so over the region in which an elongated coiled electrode is located and which can optionally be manufactured starting from a single extruded tubular lead body of constant diameter and the lead so produced. Rather than molding the electrode into the surface of the lead or machining the electrode so that it is flush with the surface of the lead, the present invention instead employs an extruded, multiple lumen lead body of circular cross-section which has material cut away or otherwise removed in one or more regions spaced from one another around the lead body and extending longitudinally along the region of the lead body where the coil electrode is to be located or a lead body which is so molded. The areas in which material is removed or is absent are preferably located in regions where the lead body wall is thickest, for example between adjacent lumens. The removal of material may result in one or more elongated, generally planar surfaces spaced from one another around the circumference of the lead body or may result in elongated indentations spaced from one another around the circumference of the lead body. The removal or absence of material renders the lead body more compressible in the region the electrode is to be located.
摘要翻译：一种制造在其中设置有细长卷绕电极的区域上是等距或接近的引线的方法，其可以任选地从具有恒定直径的单个挤出管状引线体和由此产生的引线开始制造。不是将电极模制到引线的表面或加工电极以使其与引线的表面齐平，而是本发明使用具有圆形横截面的挤出的多腔引线体，其具有切除的材料或否则在围绕引线主体彼此间隔开的一个或多个区域中移除，并沿着线体电极要被定位的引线体的区域或者如此模制的引线体纵向延伸。材料被去除或不存在的区域优选地位于引线体壁最厚的区域中，例如在相邻流明之间。去除材料可能导致一个或多个细长的，大致平坦的表面围绕引线主体的圆周彼此间隔开，或者可能导致围绕引线主体的圆周彼此间隔开的细长的凹陷。材料的去除或不存在使得引线体在电极将被定位的区域中更加可压缩。

6. 发明授权

US06185464B2 Arrangement for planting an endocardial cardiac lead 失效
标题翻译：种植心内膜心脏铅的安排
公开(公告)号：US06185464B2
公开(公告)日：2001-02-06
申请号：US09262387
申请日：1999-03-04
申请人： Matthew D. Bonner , Timothy G. Laske
发明人： Matthew D. Bonner , Timothy G. Laske
IPC分类号： A61N100
CPC分类号： A61N1/056 , A61M25/0043 , A61M25/01 , A61N2001/0578
摘要： An arrangement for introducing and implanting the electrode(s) of an endocardial implantable cardiac lead at a cardiac implantation site within a heart chamber or vessel. An elongated guide body formed of flexible material and extending between a guide body proximal end and a guide body distal end is advanced transvenously to position the guide body distal end in relation to the cardiac implantation site. A guide body tracking mechanism is coupled with the lead distal end for receiving and slidingly engaging the guide body to allow the cardiac lead to be advanced along the guide body until the electrode is positioned at the cardiac implantation site. A pusher mechanism formed of an elongated pusher body of flexible material extends between a pusher body proximal end and a pusher body distal end and has a cardiac lead engaging mechanism for engaging the cardiac lead at or adjacent the distal lead end. The pusher body has sufficient column strength to be advanced alongside the guide body and lead body with the cardiac lead engaging mechanism engaging and slidingly advancing the guide body tracking mechanism and the cardiac lead distally along the guide body to thereby allow the cardiac lead to be advanced along the guide body until the electrode is positioned at the cardiac implantation site. The lead body is released from the lead engaging mechanism and fixed, if the lead includes a fixation mechanism. The pusher mechanism is retracted by retraction of the pusher body.
摘要翻译：用于在心室或血管内的心脏植入部位处引入和植入心内可植入心脏引线的电极的装置。由柔性材料形成并在引导体近端和引导体远端之间延伸的细长引导体相对于心脏植入部位传递推进以引导体远端。引导体跟踪机构与引线远端联接，用于接收和滑动地接合引导体，以允许心脏引线沿引导体前进，直到电极定位在心脏植入部位。由细长的柔性材料推动器构成的推动机构在推动体本体近端和推动体本体远端之间延伸，并且具有心脏引线接合机构，用于在远侧引线端处或与其相邻的心脏引线接合。推动器主体具有足够的柱强度，使引导体和引线体沿着引导体接合并使引导体跟踪机构和心引导体沿引导体向远侧滑动地前进，从而允许心导线前进沿着引导体直到电极位于心脏植入部位。如果引线包括固定机构，则引线体从引线接合机构释放并固定。推动器机构通过推动器主体的缩回缩回。

7. 发明授权

US5728149A Integral spiral band electrode for transvenous defibrillation leads 失效
标题翻译：用于经静脉除颤导联的整体螺旋带电极
公开(公告)号：US5728149A
公开(公告)日：1998-03-17
申请号：US580006
申请日：1995-12-20
申请人： Timothy G. Laske , Matthew D. Bonner , Jon M. Ocel
发明人： Timothy G. Laske , Matthew D. Bonner , Jon M. Ocel
IPC分类号： A61N1/05 , A61B5/04
CPC分类号： A61N1/056
摘要： A cardioversion/defibrillation lead, and method of manufacture thereof, for location in a human heart. An elongated lead body having an insulating outer sheath extends between proximal and distal ends thereof, and an elongated defibrillation conductor within the lead body extends from a connector at the proximal end to a distal end at a predetermined location along the lead body length. A spiral band defibrillation electrode extends in spiral turns around the exterior of the insulating outer sheath for a pre-determined defibrillation electrode length. The defibrillation electrode is fabricated of a single tube of body compatible, electrically conductive material having first and second tube ends and an inside diameter selected to fit over the outer sheath and the internally disposed defibrillation lead conductor. At least one (and preferably a plurality) spiral slit is formed therein extending from first and second slit end points, spaced from the first and second ends, respectively, thereby forming at least one spiral band integrally attached to first and second end bands, respectively. At least one of the first and second end bands is attached to the defibrillation lead conductor at or near the distal end thereof. In other embodiments, intermediate connection bands are formed along the length of the spiral band, and electrical connections are made between such intermediate connection bands and the defibrillation lead conductor.
摘要翻译：心脏复律/除颤引线及其制造方法，用于在人心脏中定位。具有绝缘外护套的细长引线主体在其近端和远端之间延伸，并且引线主体内的细长除颤导体沿着引线本体长度从近端处的连接器延伸到预定位置处的远端。螺旋带除颤电极围绕绝缘外护套的外部螺旋形旋转，以预定的除颤电极长度。除颤电极由具有第一和第二管端的单体体相容的导电材料制成，并且内径选择为配合在外护套和内部设置的除颤引线导体上。至少一个（并且优选多个）螺旋狭缝形成在其中，从第一和第二狭缝端点分别与第一和第二端分开延伸，从而分别形成至少一个与第一和第二端带整体连接的螺旋带。第一和第二端带中的至少一个在其远端处或附近附接到除颤引线导体。在其他实施例中，沿着螺旋带的长度形成中间连接带，并且在这种中间连接带和除颤引线导体之间形成电连接。

8. 发明授权

US08886311B2 Techniques for mitigating motion artifacts from implantable physiological sensors 有权
标题翻译：用于减轻植入式生理传感器运动伪影的技术
公开(公告)号：US08886311B2
公开(公告)日：2014-11-11
申请号：US13360149
申请日：2012-01-27
申请人： David A. Anderson , Noah D. Barka , Erin D. Grassl , Matthew D. Bonner
发明人： David A. Anderson , Noah D. Barka , Erin D. Grassl , Matthew D. Bonner
IPC分类号： A61N1/365
CPC分类号： A61B5/0205 , A61B5/0006 , A61B5/026 , A61B5/0261 , A61B5/042 , A61B5/046 , A61B5/0538 , A61B5/11 , A61B5/1116 , A61B5/14552 , A61B5/6867 , A61B5/7207 , A61B7/003 , A61B7/023 , A61B7/04 , A61N1/3622 , A61N1/3627 , A61N1/36514 , A61N1/36521 , A61N1/36557 , A61N1/36571 , A61N1/36578 , A61N1/36585
摘要： Disclosed techniques include monitoring a physiological characteristic of a patient with a sensor that is mounted to an inner wall of a thoracic cavity of the patient, and sending a signal based on the monitored physiological characteristic from the sensor to a remote device.
摘要翻译：所公开的技术包括使用安装到患者胸腔内壁的传感器监测患者的生理特征，以及基于所监测的生理特征从传感器向远程设备发送信号。

9. 发明申请

US20130184727A1 VESSEL SUPPORT DEVICE AND METHOD OF VESSEL HARVESTING 审中-公开
标题翻译：船舶支持装置和船舶收集方法
公开(公告)号：US20130184727A1
公开(公告)日：2013-07-18
申请号：US12445919
申请日：2007-10-16
申请人： Cynthia T. Clague , Michael J. Hobday , Raymond W. Usher , Roderick E. Briscoe , Katherine S. Jolly , Ana R. Menk , Christopher P. Olig , Eric A. Meyer , Steven C. Christian , Thomas P. Daigle , Robert H. Reetz , Jeffrey D. Sandstrom , James R. Keogh , Matthew D. Bonner , Scott E. Jahns , Philip J. Haarstad
发明人： Cynthia T. Clague , Michael J. Hobday , Raymond W. Usher , Roderick E. Briscoe , Katherine S. Jolly , Ana R. Menk , Christopher P. Olig , Eric A. Meyer , Steven C. Christian , Thomas P. Daigle , Robert H. Reetz , Jeffrey D. Sandstrom , James R. Keogh , Matthew D. Bonner , Scott E. Jahns , Philip J. Haarstad
IPC分类号： A61B17/32
CPC分类号： A61B17/32 , A61B17/00008 , A61B17/3205 , A61B17/32053 , A61B2017/320064
摘要： Embodiments of the invention provide a vessel support system and a method of vessel harvesting. The system can include a cutting device, a catheter adapted to be inserted into a section of the vessel in order to support the vessel as the cutting device is advanced over the vessel, and a cannula adapted to be coupled to the vessel and adapted to receive the catheter as the catheter is inserted into the section of the vessel. The method can include orienting a cutting device coaxially with the cannula and the catheter and advancing the cutting device over the cannula, the catheter, and the section of the vessel in order to core out the section of the vessel and a portion of the surrounding tissue.
摘要翻译：本发明的实施例提供了一种血管支持系统和血管收集方法。该系统可以包括切割装置，适于插入到容器的一部分中的导管，以便当切割装置前进在容器上时支撑容器，以及适于联接到容器并适于接收的套管作为导管的导管插入血管的部分。该方法可以包括将切割装置与套管和导管同轴定向，并将切割装置推进套管，导管和容器的部分，以便将血管的一部分和周围组织的一部分。

10. 发明授权

US08480696B2 Minimally invasive coring vein harvester 有权
标题翻译：微创取芯静脉收割机
公开(公告)号：US08480696B2
公开(公告)日：2013-07-09
申请号：US11155533
申请日：2005-06-16
申请人： Cynthia T. Clague , Michael J. Hobday , Raymond W. Usher , Roderick E. Briscoe , Katherine S. Jolly , Ana R. Buhr , Christopher P. Olig , Eric A. Meyer , Steven C. Christian , Tom P. Daigle , Robert H. Reetz , Jeffrey D. Sandstrom , James R. Keogh , Matthew D. Bonner , Scott E. Jahns
发明人： Cynthia T. Clague , Michael J. Hobday , Raymond W. Usher , Roderick E. Briscoe , Katherine S. Jolly , Ana R. Buhr , Christopher P. Olig , Eric A. Meyer , Steven C. Christian , Tom P. Daigle , Robert H. Reetz , Jeffrey D. Sandstrom , James R. Keogh , Matthew D. Bonner , Scott E. Jahns
IPC分类号： A61B17/22
CPC分类号： A61B17/22 , A61B17/00008 , A61B17/320016 , A61B17/32002 , A61B17/32053 , A61B2017/00557 , A61B2017/00778 , A61B2017/22062 , A61B2017/22068
摘要： The invention provides a system and method for harvesting a vessel section. The system comprises a vessel support member, a handle, and a tubular cutting device. The vessel support member is introduced into the vessel section to be harvested. The tubular cutting device may comprise an outer tubular member or an outer and an inner tubular member. The outer tubular member carries at least one cutting element. The tubular member or members are advanced over the vessel section and vessel support member to core out the vessel section and tissue adjoining the vessel section.
摘要翻译：本发明提供了一种收集血管部分的系统和方法。该系统包括容器支撑构件，手柄和管状切割装置。将容器支撑构件引入待收获的容器部分。管状切割装置可以包括外部管状构件或外部管状构件和内部管状构件。外部管状构件承载至少一个切割元件。管状构件在容器部分和容器支撑构件上前进，以将与容器部分相邻的容器部分和组织芯出。

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