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1. 发明申请

US20120009662A1 METHOD OF FABRICATING MICROFLUIDIC SYSTEMS 有权
标题翻译：微流体系统的制备方法
公开(公告)号：US20120009662A1
公开(公告)日：2012-01-12
申请号：US13003647
申请日：2009-07-10
申请人： Wei Shen , Xu Li , Junfei Tian , Mohidus Samad Khan , Gil Garnier
发明人： Wei Shen , Xu Li , Junfei Tian , Mohidus Samad Khan , Gil Garnier
IPC分类号： C12M1/00 , G03F7/20
CPC分类号： D21H17/17 , B01L3/502707 , B01L2200/10 , B01L2200/12 , B01L2300/126 , B01L2300/161 , D21H17/16 , D21H19/10 , D21H21/16 , Y10T436/11
摘要： A method of fabricating a microfluidic system having microfluidic channels on a surface of a hydrophilic substrate, the method including the steps of: hydrophobizing the substrate surface; locating a mask defining the substrate surface, the mask having open areas defining the periphery of the microfluidic channels; and applying an irradiation treatment to areas of the substrate surface exposed by the open areas of the mask, said exposed areas becoming hydrophilic to therefore form said microfluidic channels.
摘要翻译：一种在亲水基材的表面上制造具有微流体通道的微流体系统的方法，所述方法包括以下步骤：使基材表面疏水化; 定位限定衬底表面的掩模，所述掩模具有限定所述微流体通道的周边的开口区域; 以及对由所述掩模的开放区域暴露的所述衬底表面的区域进行照射处理，所述暴露区域变得亲水，从而形成所述微流体通道。

2. 发明授权

US08852526B2 Method of fabricating microfluidic systems 有权
标题翻译：制造微流体系统的方法
公开(公告)号：US08852526B2
公开(公告)日：2014-10-07
申请号：US13003647
申请日：2009-07-10
申请人： Wei Shen , Xu Li , Junfei Tian , Mohidus Samad Khan , Gil Garnier
发明人： Wei Shen , Xu Li , Junfei Tian , Mohidus Samad Khan , Gil Garnier
IPC分类号： G01N15/06 , G01N33/00 , G01N33/48 , D21H21/16 , D21H17/17 , D21H17/16 , D21H19/10 , B01L3/00
CPC分类号： D21H17/17 , B01L3/502707 , B01L2200/10 , B01L2200/12 , B01L2300/126 , B01L2300/161 , D21H17/16 , D21H19/10 , D21H21/16 , Y10T436/11
摘要： A method of fabricating a microfluidic system having microfluidic channels on a surface of a hydrophilic substrate, the method including the steps of: hydrophobizing the substrate surface; locating a mask defining the substrate surface, the mask having open areas defining the periphery of the microfluidic channels; and applying an irradiation treatment to areas of the substrate surface exposed by the open areas of the mask, said exposed areas becoming hydrophilic to therefore form said microfluidic channels.
摘要翻译：一种在亲水基材的表面上制造具有微流体通道的微流体系统的方法，所述方法包括以下步骤：使基材表面疏水化; 定位限定衬底表面的掩模，所述掩模具有限定所述微流体通道的周边的开口区域; 以及对由所述掩模的开放区域暴露的所述衬底表面的区域进行照射处理，所述暴露区域变得亲水，从而形成所述微流体通道。

3. 发明申请

US20120322086A1 TESTING DEVICE FOR IDENTIFYING ANTIGENS AND ANTIBODIES IN BIOFLUIDS 审中-公开
标题翻译：用于识别生物体内的抗原和抗体的测试装置
公开(公告)号：US20120322086A1
公开(公告)日：2012-12-20
申请号：US13497704
申请日：2010-09-24
申请人： Gil Garnier , Wei Shen , Mohidus Samad Khan , Xu Li , George Thouas
发明人： Gil Garnier , Wei Shen , Mohidus Samad Khan , Xu Li , George Thouas
IPC分类号： C12M1/34 , G01N21/82
CPC分类号： G01N33/80 , G01N21/82 , G01N30/90 , G01N33/558 , G01N2021/752 , G01N2021/757 , G01N2021/825 , Y02A50/58
摘要： A testing device for identifying an antigen or antibody within a biofluid sample including: a substrate having a hydrophilic surface thereon; the surface including a collection zone, and at least one detection zone extending therefrom; wherein the biofluid sample can be mixed with a specific antigen or antibody, and deposited on the collection zone and transferred by capillary action to the detection zone; the antigen or antibody in the biofluid sample reacting with an appropriate said antibody or antigen thereby resulting in a visual indication within the detection zone.
摘要翻译：一种用于鉴定生物流体样品内的抗原或抗体的测试装置，包括：其上具有亲水表面的基底; 所述表面包括收集区，以及至少一个从其延伸的检测区; 其中所述生物流体样品可以与特定的抗原或抗体混合，并且沉积在所述收集区上并通过毛细作用转移到所述检测区; 生物流体样品中的抗原或抗体与合适的所述抗体或抗原反应，从而导致检测区内的视觉指示。

4. 发明授权

US09116146B2 Quantitative and self-calibrating chemical analysis using paper-based microfluidic systems 有权
标题翻译：使用纸基微流体系统的定量和自校准化学分析
公开(公告)号：US09116146B2
公开(公告)日：2015-08-25
申请号：US13380303
申请日：2010-06-30
申请人： Wei Shen , Xu Li , Junfei Tian , Gil Garnier
发明人： Wei Shen , Xu Li , Junfei Tian , Gil Garnier
IPC分类号： B01L3/00 , G01N33/52 , G01N33/543 , G01N21/93 , G01N21/78 , G01N33/53 , G01N33/558
CPC分类号： G01N33/52 , B01L3/50273 , B01L2300/0816 , B01L2300/0864 , B01L2300/126 , B01L2400/0406 , G01N21/78 , G01N21/93 , G01N33/5302 , G01N33/543 , G01N33/54366 , G01N33/54386 , G01N33/558 , Y10T436/148888 , Y10T436/173076
摘要： A method of determining the concentration of a test fluid sample using a paper-based microfluidic system having a plurality of hydrophilic testing zones, including: a) depositing said test fluid sample on at least one said testing zone; b) depositing a plurality of standard fluid samples or reactives of differing known concentrations on other said testing zones; c) introducing an indicator solution to each said test zone to thereby react with the deposited fluid sample and result in a color intensity change which is a function of the fluid sample concentration; and d) comparing the differences in color intensity between the test fluid sample and the standard fluid samples or reactives to thereby determine the concentration of said test fluid sample.
摘要翻译：一种使用具有多个亲水测试区域的基于纸的微流体系统确定测试流体样品的浓度的方法，包括：a）将所述测试流体样品沉积在至少一个所述测试区域上; b）在其他所述测试区域上沉积不同已知浓度的多个标准流体样品或反应物; c）向每个所述测试区域引入指示剂溶液，从而与沉积的流体样品反应并导致作为流体样品浓度的函数的颜色强度变化; 以及d）比较测试流体样品和标准流体样品或反应物之间的颜色强度的差异，从而确定所述测试流体样品的浓度。

5. 发明申请

US20120171702A1 QUANTITATIVE AND SELF-CALIBRATING CHEMICAL ANALYSIS USING PAPER-BASED MICROFLUIDIC SYSTEMS 有权
标题翻译：使用基于纸张的微流体系统的量化和自我校准化学分析
公开(公告)号：US20120171702A1
公开(公告)日：2012-07-05
申请号：US13380303
申请日：2010-06-30
申请人： Wei Shen , Xu Li , Junfei Tian , Gil Garnier
发明人： Wei Shen , Xu Li , Junfei Tian , Gil Garnier
IPC分类号： G01N21/25 , B01L3/00
CPC分类号： G01N33/52 , B01L3/50273 , B01L2300/0816 , B01L2300/0864 , B01L2300/126 , B01L2400/0406 , G01N21/78 , G01N21/93 , G01N33/5302 , G01N33/543 , G01N33/54366 , G01N33/54386 , G01N33/558 , Y10T436/148888 , Y10T436/173076
摘要： A method of determining the concentration of a test fluid sample using a paper-based microfluidic system having a plurality of hydrophilic testing zones, including: a) depositing said test fluid sample on at least one said testing zone; b) depositing a plurality of standard fluid samples or reactives of differing known concentrations on other said testing zones; c) introducing an indicator solution to each said test zone to thereby react with the deposited fluid sample and result in a colour intensity change which is a function of the fluid sample concentration; and d) comparing the differences in colour intensity between the test fluid sample and the standard fluid samples or reactives to thereby determine the concentration of said test fluid sample.
摘要翻译：一种使用具有多个亲水测试区域的基于纸的微流体系统确定测试流体样品的浓度的方法，包括：a）将所述测试流体样品沉积在至少一个所述测试区域上; b）在其他所述测试区域上沉积不同已知浓度的多个标准流体样品或反应物; c）向每个所述测试区域引入指示剂溶液，从而与沉积的流体样品反应并导致作为流体样品浓度的函数的颜色强度变化; 以及d）比较测试流体样品和标准流体样品或反应物之间的颜色强度的差异，从而确定所述测试流体样品的浓度。

6. 发明授权

US09011798B2 Switches for microfluidic systems 有权
标题翻译：微流体系统开关
公开(公告)号：US09011798B2
公开(公告)日：2015-04-21
申请号：US13058449
申请日：2009-08-10
申请人： Wei Shen , Xu Li , Junfie Tian , Thanh Huynh Nguyen , Gil Garnier
发明人： Wei Shen , Xu Li , Junfie Tian , Thanh Huynh Nguyen , Gil Garnier
IPC分类号： B01L99/00 , G01N33/00 , B01L3/00 , F16K99/00
CPC分类号： B01L3/502707 , B01L3/5023 , B01L3/502738 , B01L2200/10 , B01L2300/0864 , B01L2300/0867 , B01L2300/087 , B01L2300/0874 , B01L2300/0887 , B01L2300/126 , B01L2400/0406 , B01L2400/0622 , B01L2400/0633 , B01L2400/0677 , B01L2400/0688 , F16K99/0001 , F16K2099/0074 , F16K2099/008 , F16K2099/0084 , F16K2099/0086 , F16K2099/0092 , Y10T83/02 , Y10T436/2575
摘要： A microfluidic system including a substrate in sheet form, at least one hydrophilic microfluidic channel supported on a surface of the substrate, and at least one functional component formed as part of the substrate for providing a functional component for the microfluidic channel wherein the functional component comprises at least one cut within the substrate for providing a switch or filter component for the microfluidic channel.
摘要翻译：一种微流体系统，其包括片状基材，至少一个支撑在该基底表面上的亲水性微流体通道，以及至少一种形成为该基底的一部分的功能组分，用于提供该微流体通道的功能组分，其中该功能组分包含衬底内的至少一个切口，用于为微流体通道提供开关或过滤器部件。

7. 发明申请

US20110318227A1 SWITCHES FOR MICROFLUIDIC SYSTEMS 有权
标题翻译：微流控系统开关
公开(公告)号：US20110318227A1
公开(公告)日：2011-12-29
申请号：US13058449
申请日：2009-08-10
申请人： Wei Shen , Xu Li , Junfie Tian , Thanh Huynh Nguyen , Gil Garnier
发明人： Wei Shen , Xu Li , Junfie Tian , Thanh Huynh Nguyen , Gil Garnier
IPC分类号： B01L3/00 , B26D3/00 , G01N33/00
CPC分类号： B01L3/502707 , B01L3/5023 , B01L3/502738 , B01L2200/10 , B01L2300/0864 , B01L2300/0867 , B01L2300/087 , B01L2300/0874 , B01L2300/0887 , B01L2300/126 , B01L2400/0406 , B01L2400/0622 , B01L2400/0633 , B01L2400/0677 , B01L2400/0688 , F16K99/0001 , F16K2099/0074 , F16K2099/008 , F16K2099/0084 , F16K2099/0086 , F16K2099/0092 , Y10T83/02 , Y10T436/2575
摘要： A microfluidic system including a substrate in sheet form, at least one hydrophilic microfluidic channel supported on a surface of the substrate, and at least one function component formed as part of the substrate for providing a functional component for the microfluidic channel wherein the functional component comprises at least one cut within the substrate for providing a switch or filter component for the microfluidic channel.
摘要翻译：一种微流体系统，其包括片状的底物，至少一个支撑在该基底的表面上的亲水性微流体通道，以及形成为该基底的一部分的至少一个功能组分，用于提供该微流体通道的功能组分，其中该功能组分包含衬底内的至少一个切口，用于为微流体通道提供开关或过滤器部件。

8. 发明授权

US06824650B2 Fibrous materials treated with a polyvinylamine polymer 有权
标题翻译：用聚乙烯胺聚合物处理的纤维材料
公开(公告)号：US06824650B2
公开(公告)日：2004-11-30
申请号：US10023489
申请日：2001-12-18
申请人： Jeff Lindsay , Tom G. Shannon , Mike Goulet , Mike Lostocco , Troy Runge , Kelly Branham , Lisa Flugge , Jamie Foster , Fred Lang , Tong Sun , Gil Garnier
发明人： Jeff Lindsay , Tom G. Shannon , Mike Goulet , Mike Lostocco , Troy Runge , Kelly Branham , Lisa Flugge , Jamie Foster , Fred Lang , Tong Sun , Gil Garnier
IPC分类号： D21H2376
CPC分类号： D21H21/18 , D21H17/24 , D21H17/34 , D21H17/36 , D21H17/42 , D21H17/56 , D21H17/72 , D21H23/76 , D21H27/002
摘要： Textile materials, including paper webs, treated with a polyvinylamine polymer and a second agent that interacts with the polyvinylamine polymer is disclosed. The second agent added with the polyvinylamine polymer can be, for instance, a polymeric anionic reactive compound or a polymeric aldehyde-functional compound. When incorporated into a paper web, the combination of the polyvinylamine polymer and the second agent provide improved strength properties, such as wet strength properties. In an alternative embodiment, the polyvinylamine polymer and the second polymer can be applied to a textile material for increasing the affinity of the textile material for acid dyes.
摘要翻译：公开了用聚乙烯胺聚合物处理的纺织材料，包括纸幅，以及与聚乙烯胺聚合物相互作用的第二试剂。加入聚乙烯胺聚合物的第二种试剂可以是例如聚合阴离子反应性化合物或聚合醛官能化合物。当结合到纸幅中时，聚乙烯胺聚合物和第二剂的组合提供了改进的强度性能，例如湿强度性质。在替代实施方案中，聚乙烯胺聚合物和第二聚合物可以施加到织物材料上，以增加织物材料对酸性染料的亲和力。

9. 发明申请

US20060065380A1 Bicomponent strengthening system for paper 审中-公开
标题翻译：纸张双组份强化系统
公开(公告)号：US20060065380A1
公开(公告)日：2006-03-30
申请号：US11281109
申请日：2005-11-17
申请人： Gil Garnier , Jeffrey Lindsay , Thomas Shannon , Michael Lostocco , Lacey Hansen , Kelly Branham , Dan Siderius
发明人： Gil Garnier , Jeffrey Lindsay , Thomas Shannon , Michael Lostocco , Lacey Hansen , Kelly Branham , Dan Siderius
IPC分类号： D21H21/20
CPC分类号： D21H17/56 , D21H17/20 , D21H17/37 , D21H17/42 , D21H17/71 , D21H23/04
摘要： The present invention is directed to a bicomponent strengthening system and the paper webs produced with the bicomponent strengthening system. Through use of the strengthening system, paper webs may be produced in which the strength characteristics of the web may be specifically tailored. The first component of the system comprises a polymer having at least about 1.5 m-eq primary amine functionality per gram of polymer and a molecular weight of at least about 10,000 Daltons. The second component may be either a polymeric anionic compound or a polymeric aldehyde functional compound. For example, the polyamine polymer component may be a polyvinylamine or polysaccharide having primary amine functionality. In one embodiment, the second component may be a cationic polymeric aldehyde functional compound. For example, the second component may be a cationic glyoxylated polyacrylamide. In another embodiment, the second component may be a polymeric anionic compound comprising carboxy functionality.
摘要翻译：本发明涉及双组分强化体系和由双组分强化体系生产的纸幅。通过使用强化系统，可以制造纸幅，其中纤维网的强度特性可以被特别地定制。该体系的第一组分包含具有至少约1.5m当量伯胺官能度/克聚合物和分子量至少约10,000道尔顿的聚合物。第二组分可以是聚合阴离子化合物或聚合醛官能化合物。例如，聚胺聚合物组分可以是具有伯胺官能团的聚乙烯胺或多糖。在一个实施方案中，第二组分可以是阳离子聚合醛官能化合物。例如，第二组分可以是阳离子乙醛酸聚丙烯酰胺。在另一个实施方案中，第二组分可以是包含羧基官能团的聚合阴离子化合物。

10. 发明申请

US20050137542A1 Live graphics on absorbent articles using electrochromic displays 审中-公开
标题翻译：使用电致变色显示器的吸收制品上的实时图形
公开(公告)号：US20050137542A1
公开(公告)日：2005-06-23
申请号：US10742611
申请日：2003-12-19
申请人： Rick Underhill , Jeffrey Lindsay , Fung-jou Chen , Gil Garnier
发明人： Rick Underhill , Jeffrey Lindsay , Fung-jou Chen , Gil Garnier
IPC分类号： A61F13/15 , A61F13/20 , A61F13/42 , G02F1/153
CPC分类号： A61F13/42 , A61F2013/8479 , A61F2013/8497 , G02F1/153
摘要： An absorbent article is provided that includes an electroactive display. The electroactive display may include an electrochromic composition positioned between two electrodes. The electroactive display is configured to create and exhibit an image that contains active features such as moving graphics or color-changing objects. For instance, the electroactive display may display an animated cartoon character or a moving vehicle. The electroactive display may also create symbols or words. When combined with sensors, a power source, and the proper circuitry, the electroactive display may be used, for instance, as a wetness indicator or to indicate the presence of a particular substance. In other embodiments, the electroactive display may be used solely for aesthetic purposes.
摘要翻译：提供了一种包括电活性显示器的吸收制品。电活性显示器可以包括位于两个电极之间的电致变色组合物。电活动显示器被配置为创建和展示包含诸如移动图形或变色对象的活动特征的图像。例如，电动显示器可以显示动画卡通人物或移动车辆。电活动显示器还可以创建符号或单词。当与传感器，电源和适当的电路组合时，电活性显示器可以用作例如湿度指示器或指示特定物质的存在。在其它实施例中，电活性显示器可以仅用于美学目的。

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