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1. 发明申请

US20100087373A1 DETECTION AND THERAPY OF BACTERIAL INFECTION CAUSED BY ENTEROBACTERIACEAE 有权
标题翻译：肠杆菌引起的细菌感染的检测和治疗
公开(公告)号：US20100087373A1
公开(公告)日：2010-04-08
申请号：US12569363
申请日：2009-09-29
申请人： Yi-Yuan Yang , Hsueh-Hsia Wu , Sy-Jye Leu , Neng-Yao Shih , I-Jen Huang , Ching-Yu Lin , Wen-Shyang Hsieh , Ko-Jiunn Liu , Shih-Yi Huang , Yung-Luen Shih , Chi-Hsin Lee , Yuan-Soon Ho , Shih-Lan Hsu
发明人： Yi-Yuan Yang , Hsueh-Hsia Wu , Sy-Jye Leu , Neng-Yao Shih , I-Jen Huang , Ching-Yu Lin , Wen-Shyang Hsieh , Ko-Jiunn Liu , Shih-Yi Huang , Yung-Luen Shih , Chi-Hsin Lee , Yuan-Soon Ho , Shih-Lan Hsu
IPC分类号： A61K38/16 , A61K39/02 , C07K16/12 , G01N33/53
CPC分类号： A61K38/164 , C07K16/1232 , C07K2317/11 , C07K2317/23 , C07K2317/76 , G01N33/56916 , G01N33/6893 , G01N2800/26
摘要： The present invention provides a method for the treatment and/or prevention of bacterial infection caused by Enterobacteriaceae bacteria in central nervous system and/or peripheral blood circulation in a mammal by administering effective amount of outer membrane protein A (OmpA) or its derivatives to a mammal. Also provided are a method for vaccinating a mammal to produce an antibody against bacterial infection caused by Enterobacteriaceae family in central nervous system and/or peripheral blood circulation and a method of detecting or diagnosing bacterial infections caused by Enterobacteriaceae family in central nervous system and/or peripheral blood circulation in a mammal. An antibody and a kit on the basis of the vaccinating method and detecting/diagnosing method are also provided.
摘要翻译：本发明提供了一种通过将有效量的外膜蛋白A（OmpA）或其衍生物施用于哺乳动物的中枢神经系统和/或外周血循环中由肠杆菌科细菌引起的细菌感染的治疗和/或预防方法哺乳动物。还提供了一种用于接种哺乳动物以在中枢神经系统和/或外周血循环中产生由肠杆菌科家族引起的细菌感染的抗体的方法，以及检测或诊断由中枢神经系统中肠杆菌科家族引起的细菌感染的方法和/或哺乳动物的外周血循环。还提供了基于疫苗接种方法和检测/诊断方法的抗体和试剂盒。

2. 发明授权

US08361441B2 Detection and therapy of bacterial infection caused by Enterobacteriaceae 有权
标题翻译：检测和治疗由肠杆菌科引起的细菌感染
公开(公告)号：US08361441B2
公开(公告)日：2013-01-29
申请号：US12569363
申请日：2009-09-29
申请人： Yi-Yuan Yang , Hsueh-Hsia Wu , Sy-Jye Leu , Neng-Yao Shih , I-Jen Huang , Wen-Shyang Hsieh , Ko-Jiunn Liu , Shih-Yi Huang , Yung-Luen Shih , Chi-Hsin Lee , Yuan-Soon Ho , Shih-Lan Hsu
发明人： Yi-Yuan Yang , Hsueh-Hsia Wu , Sy-Jye Leu , Neng-Yao Shih , I-Jen Huang , Wen-Shyang Hsieh , Ko-Jiunn Liu , Shih-Yi Huang , Yung-Luen Shih , Chi-Hsin Lee , Yuan-Soon Ho , Shih-Lan Hsu
IPC分类号： A61K49/00 , A61K39/02 , A61K39/112
CPC分类号： A61K38/164 , C07K16/1232 , C07K2317/11 , C07K2317/23 , C07K2317/76 , G01N33/56916 , G01N33/6893 , G01N2800/26
摘要： The present invention provides a method for the treatment and/or prevention of bacterial infection caused by Enterobacteriaceae bacteria in central nervous system and/or peripheral blood circulation in a mammal by administering effective amount of outer membrane protein A (OmpA) or its derivatives to a mammal. Also provided are a method for vaccinating a mammal to produce an antibody against bacterial infection caused by Enterobacteriaceae family in central nervous system and/or peripheral blood circulation and a method of detecting or diagnosing bacterial infections caused by Enterobacteriaceae family in central nervous system and/or peripheral blood circulation in a mammal. An antibody and a kit on the basis of the vaccinating method and detecting/diagnosing method are also provided.
摘要翻译：本发明提供了一种通过将有效量的外膜蛋白A（OmpA）或其衍生物施用于哺乳动物的中枢神经系统和/或外周血循环中由肠杆菌科细菌引起的细菌感染的治疗和/或预防方法哺乳动物。还提供了一种用于接种哺乳动物以在中枢神经系统和/或外周血循环中产生由肠杆菌科家族引起的细菌感染的抗体的方法，以及检测或诊断由中枢神经系统中肠杆菌科家族引起的细菌感染的方法和/或哺乳动物的外周血循环。还提供了基于疫苗接种方法和检测/诊断方法的抗体和试剂盒。

3. 发明授权

US07807139B2 Use of outer membrane protein A (OMPA) in treatment/prevention/diagnosis of infections caused by Klebsiella pneumoniae and other gram-negative bacteria 有权
标题翻译：使用外膜蛋白A（OMPA）治疗/预防/诊断由肺炎克雷伯杆菌和其他革兰氏阴性细菌引起的感染
公开(公告)号：US07807139B2
公开(公告)日：2010-10-05
申请号：US12359205
申请日：2009-01-23
申请人： Yi-Yuan Yang , Hsueh-Hsia Wu , Sy-Jye Leu , Neng-Yao Shih , I-Jen Huang , Ching-Yu Lin , Wen-Shyang Hsieh , Ko-Jiunn Liu , Shih-Yi Huang , Yueh-Lun Lee , Chi-Hsin Lee , Yuan-Soon Ho , Shih-Lan Hsu
发明人： Yi-Yuan Yang , Hsueh-Hsia Wu , Sy-Jye Leu , Neng-Yao Shih , I-Jen Huang , Ching-Yu Lin , Wen-Shyang Hsieh , Ko-Jiunn Liu , Shih-Yi Huang , Yueh-Lun Lee , Chi-Hsin Lee , Yuan-Soon Ho , Shih-Lan Hsu
IPC分类号： A61K49/00 , A61K39/00 , A61K39/108
CPC分类号： G01N33/56916 , A61K38/164 , A61K39/025 , G01N2469/10 , Y02A50/474 , Y02A50/482 , Y02A50/484
摘要： The present invention provides a method for the treatment and/or prevention of bacterial infection caused by Klebsiella pneumoniae and other gram-negative bacteria in central nervous system and/or peripheral blood circulation in a mammal by administering effective amount of outer membrane protein A (OmpA) or its derivatives to a mammal. Also provided are a method for vaccinating a mammal to produce an antibody against bacterial infection caused by Enterobacteriaceae family in central nervous system and/or peripheral blood circulation and a method of detecting or diagnosing bacterial infections caused by Enterobacteriaceae family in central nervous system and/or peripheral blood circulation in a mammal.
摘要翻译：本发明提供一种通过施用有效量的外膜蛋白A（OmpA）来治疗和/或预防哺乳动物的中枢神经系统和/或外周血循环中由肺炎克雷伯杆菌和其它革兰氏阴性细菌引起的细菌感染的方法）或其衍生物。还提供了一种用于接种哺乳动物以在中枢神经系统和/或外周血循环中产生由肠杆菌科家族引起的细菌感染的抗体的方法，以及检测或诊断由中枢神经系统中肠杆菌科家族引起的细菌感染的方法和/或哺乳动物的外周血循环。

4. 发明申请

US20090232852A1 USE OF OUTER MEMBRANE PROTEIN A (OMPA) IN TREATMENT/PREVENTION/DIAGNOSIS OF INFECTIONS CAUSED BY KLEBSIELLA PNEUMONIAE AND OTHER GRAM-NEGATIVE BACTERIA 有权
标题翻译：使用外膜蛋白A（OMPA）治疗/预防/诊断由克氏杆菌肺炎和其他灰质细菌引起的感染
公开(公告)号：US20090232852A1
公开(公告)日：2009-09-17
申请号：US12359205
申请日：2009-01-23
申请人： Yi-Yuan Yang , Hsueh-Hsia Wu , Sy-Jye Leu , Neng-Yao Shih , I-Jen Huang , Ching-Yu Lin , Wen-Shyang Hsieh , Ko-Jiunn Liu , Shih-Yi Huang , Yueh-Lun Lee , Chi-Hsin Lee , Yuan-Soon Ho , Shih-Lan Hsu
发明人： Yi-Yuan Yang , Hsueh-Hsia Wu , Sy-Jye Leu , Neng-Yao Shih , I-Jen Huang , Ching-Yu Lin , Wen-Shyang Hsieh , Ko-Jiunn Liu , Shih-Yi Huang , Yueh-Lun Lee , Chi-Hsin Lee , Yuan-Soon Ho , Shih-Lan Hsu
IPC分类号： A61K39/108 , A61K38/16 , A61K39/02 , G01N33/569 , A61K39/112
CPC分类号： G01N33/56916 , A61K38/164 , A61K39/025 , G01N2469/10 , Y02A50/474 , Y02A50/482 , Y02A50/484
摘要： The present invention provides a method for the treatment and/or prevention of bacterial infection caused by klebsiella pneumoniae and other gram-negative bacteria in central nervous system and/or peripheral blood circulation in a mammal by administering effective amount of outer membrane protein A (OmpA) or its derivatives to a mammal. Also provided are a method for vaccinating a mammal to produce an antibody against bacterial infection caused by Enterobacteriaceae family in central nervous system and/or peripheral blood circulation and a method of detecting or diagnosing bacterial infections caused by Enterobacteriaceae family in central nervous system and/or peripheral blood circulation in a mammal.
摘要翻译：本发明提供了一种通过施用有效量的外膜蛋白A（OmpA）来治疗和/或预防哺乳动物中枢神经系统和/或外周血循环中由肺炎克雷伯杆菌和其它革兰氏阴性细菌引起的细菌感染的方法）或其衍生物。还提供了一种用于接种哺乳动物以在中枢神经系统和/或外周血循环中产生由肠杆菌科家族引起的细菌感染的抗体的方法，以及检测或诊断由中枢神经系统中肠杆菌科家族引起的细菌感染的方法和/或哺乳动物的外周血循环。

5. 外观设计

USD411149S Framework for wheelchair 失效
公开(公告)号：USD411149S
公开(公告)日：1999-06-22
申请号：US96815
申请日：1998-11-20
申请人： Shih-Yi Huang
设计人： Shih-Yi Huang

6. 发明授权

US06902140B1 Adjustable support foot 失效
标题翻译：可调支撑脚
公开(公告)号：US06902140B1
公开(公告)日：2005-06-07
申请号：US10809404
申请日：2004-03-26
申请人： Shih-Yi Huang
发明人： Shih-Yi Huang
IPC分类号： E06C7/44 , F16M7/00 , F16M11/24
CPC分类号： F16M7/00 , E06C7/44
摘要： An adjustable support foot comprises a support post, a plurality of retaining plates, a control device and an outer shell. The support post has a base and a screwed axle erected thereon. The retaining plates each provided with a screw thread cover around the screwed axle and are further enclosed by the control device including a retaining cylinder and a control ring. The control device urges the retaining plates to engage the screwed axle or depart from the screwed axle, by which the relative position of the support post in the outer shell can be quickly or mildly changed.
摘要翻译：可调节的支撑脚包括支撑柱，多个保持板，控制装置和外壳。支撑柱具有竖立在其上的底座和螺纹轴。保持板各自在螺纹轴周围设置有螺纹盖，并且还包括包括保持筒和控制环的控制装置封闭。控制装置促使固定板与螺纹轴接合或脱离螺纹轴，由此支撑柱在外壳中的相对位置可以快速或轻微地改变。

7. 发明授权

US07100728B2 Driving mechanism of an electrically-operated vehicle 失效
标题翻译：电动车辆的驱动机构
公开(公告)号：US07100728B2
公开(公告)日：2006-09-05
申请号：US10739569
申请日：2003-12-19
申请人： Shih-Feng Huang , Shih-Yi Huang
发明人： Shih-Feng Huang , Shih-Yi Huang
IPC分类号： B60K1/00
CPC分类号： B62M7/00 , B60K1/02 , B60L11/1805 , B60L2200/12 , B60L2220/42 , B60L2220/46 , B60Y2200/126 , B62K3/002 , B62K25/283 , B62K2204/00 , Y02T10/646 , Y02T10/7005
摘要： An electric vehicle includes a rear frame, a rear axle fastened with the rear frame, a rear wheel mounted on the rear axle, and a driving mechanism mounted on the rear frame to drive both ends of the rear axle. The driving mechanism has a first motor for driving one end of the rear axle in conjunction with a first driven member and a first transmission member, and a second motor for driving the other end of the rear axle in conjunction with a second driven member and a second transmission member.
摘要翻译：一种电动车辆包括后框架，与后框架紧固的后桥，安装在后桥上的后轮，以及安装在后框架上以驱动后桥的两端的驱动机构。驱动机构具有第一马达，用于与第一从动构件和第一传动构件一起驱动后桥的一端，以及用于与第二从动构件一起驱动后桥的另一端的第二马达和第二传输构件。

8. 发明申请

US20050133282A1 Driving mechanism of an electrically-operated vehicle 失效
标题翻译：电动车辆的驱动机构
公开(公告)号：US20050133282A1
公开(公告)日：2005-06-23
申请号：US10739569
申请日：2003-12-19
申请人： Shih-Feng Huang , Shih-Yi Huang
发明人： Shih-Feng Huang , Shih-Yi Huang
IPC分类号： B60K1/02 , B62K3/00 , B62K25/28 , B62M7/00 , B60K1/00
CPC分类号： B62M7/00 , B60K1/02 , B60L11/1805 , B60L2200/12 , B60L2220/42 , B60L2220/46 , B60Y2200/126 , B62K3/002 , B62K25/283 , B62K2204/00 , Y02T10/646 , Y02T10/7005
摘要： An electric vehicle includes a rear frame, a rear axle fastened with the rear frame, a rear wheel mounted on the rear axle, and a driving mechanism mounted on the rear frame to drive both ends of the rear axle. The driving mechanism has a first motor for driving one end of the rear axle in conjunction with a first driven member and a first transmission member, and a second motor for driving the other end of the rear axle in conjunction with a second driven member and a second transmission member.
摘要翻译：一种电动车辆包括后框架，与后框架紧固的后桥，安装在后桥上的后轮，以及安装在后框架上以驱动后桥的两端的驱动机构。驱动机构具有第一马达，用于与第一从动构件和第一传动构件一起驱动后桥的一端，以及用于与第二从动构件一起驱动后桥的另一端的第二马达和第二传输构件。

9. 发明授权

US06192772B1 Controller for the brake of a rolling walkkit 失效
标题翻译：用于制动滚动步行控制器的控制器
公开(公告)号：US06192772B1
公开(公告)日：2001-02-27
申请号：US09390405
申请日：1999-09-03
申请人： Shih-Yi Huang
发明人： Shih-Yi Huang
IPC分类号： F16C112
CPC分类号： B62L3/02 , B62L3/06 , G05G1/04 , Y10T74/20287 , Y10T74/20438
摘要： A controller for the brake of a rolling walkkit includes a controller base, a grip and a connect rod combined together. The controller base has an upper cylindrical portion fixed around a handrest of the rolling walkkit and a lower hollow portion for pivotally connecting the joint member of the grip, and the control rod is pivotally connected inside said grip. When the grip is pushed up, the connect rod is moved to swing to pull forward a brake wire firmly fixed with a lower end of the connect rod to brake the wheels of the walkkit temporarily in moving, and releasing the grip lets the brake wire also loosened to let the wheels to move again. When the grip is pressed down, the connect rod is forced to swing and let the brake wire pulled forward to stop the wheels for a long time, and releasing the grip lets the brake wire recover, permitting the wheels of the walkkit move again.
摘要翻译：用于滚动步行车的制动器的控制器包括组合在一起的控制器基座，把手和连杆。所述控制器基座具有固定在所述滚动步行台的手扶板周围的上部圆柱形部分和用于枢转地连接所述把手的接合部件的下部中空部分，并且所述控制杆枢转地连接在所述把手内部。当把手被向上推时，连杆移动到摆动状态，使连接杆下端牢固固定的刹车线暂时拉动，使手柄的轮子暂时地移动，释放把手使刹车线也松开让轮子再次移动。当把手被按下时，连杆被迫摆动，让刹车线向前拉以使车轮停止很长时间，释放把手就可以使刹车线恢复，从而允许步行车的车轮再次移动。

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