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1. 发明授权

US12033842B2 Mass spectrometer and method of controlling the same 有权
公开(公告)号：US12033842B2
公开(公告)日：2024-07-09
申请号：US17628388
申请日：2020-07-22
申请人： Hitachi High-Tech Corporation
发明人： Hiroyuki Yasuda , Yuichiro Hashimoto , Yuka Sugawara , Riku Tamura
IPC分类号： H01J49/06 , G01N30/72 , G01N35/00 , H01J49/24 , H01J49/42 , G01N30/32
CPC分类号： H01J49/063 , G01N30/72 , G01N35/00584 , H01J49/24 , H01J49/42 , G01N2030/326 , G01N2030/328
摘要： There is provided a mass spectrometer that can appropriately maintain the atmospheric pressure of a vacuum chamber, and a method of controlling the same. An example of a mass spectrometer according to the present invention includes first vacuum chambers, first vacuum pumps, an atmospheric pressure relating value acquiring unit, and an adjustment unit configured to adjust the effective exhaust velocity of the first vacuum pumps, and controllers. The controllers control the adjustment unit corresponding to an atmospheric pressure relating value.

2. 发明公开

US20230386811A1 A METHOD OF CALIBRATING A MASS SPECTROMETER 审中-公开
公开(公告)号：US20230386811A1
公开(公告)日：2023-11-30
申请号：US18032702
申请日：2021-10-21
申请人： Waters Technologies Ireland LTD
发明人： Maria GAFFNEY-LOVETT , Richard DENNY
IPC分类号： H01J49/00 , H01J49/42
CPC分类号： H01J49/0009 , H01J49/0036 , H01J49/42
摘要： We provide a method of assessing an acquired mass spectrum, the method including the steps of: obtaining a model isotope pattern for a chemical compound of known elemental composition, providing mass spectrum data obtained from a mass spectrometer in analysis of the chemical compound, and performing location matching by comparing the mass spectrum data to the isotope pattern to match a reference location in the isotope pattern with respective corresponding candidate locations in the mass spectrum data, the location matching including: determining a likelihood function over the mass spectrum data, representing the likelihood that each location in the mass spectrum data correctly corresponds to the reference location of the isotope pattern, determining a set of candidate locations each corresponding to a local maxima in the determined likelihood function, and at each candidate location, determining an associated error bar based on the curvature of the likelihood function at that location.

3. 发明授权

US11749518B2 Package comprising an ion-trap and method of fabrication 有权
公开(公告)号：US11749518B2
公开(公告)日：2023-09-05
申请号：US16913932
申请日：2020-06-26
申请人： Duke University
发明人： Jungsang Kim , Kai Hudek , Geert Vrijsen , Robert Spivey , Peter Maunz
IPC分类号： H01J49/42 , G06N10/00 , H01J49/16 , H01J49/24
CPC分类号： H01J49/422 , G06N10/00 , H01J49/16 , H01J49/24 , H01J49/42
摘要： A package-level, integrated high-vacuum ion-chip enclosure having improved thermal characteristics is disclosed. Enclosures in accordance with the present invention include first and second chambers that are located on opposite sides of a chip carrier, where the chambers are fluidically coupled via a conduit through the chip carrier. The ion trap is located in the first chamber and disposed on the chip carrier. A source for generating an atomic flux is located in the second chamber. The separation of the source and ion trap in different chambers affords thermal isolation between them, while the conduit between the chambers enables the ion trap to receive the atomic flux.

4. 发明申请

US20190148122A1 ION GUIDE AND MASS SPECTROMETER USING SAME 审中-公开
公开(公告)号：US20190148122A1
公开(公告)日：2019-05-16
申请号：US16228982
申请日：2018-12-21
申请人： HITACHI HIGH-TECHNOLOGIES CORPORATION
发明人： Masuyuki SUGIYAMA , Hideki HASEGAWA , Masao SUGA , Hiroyuki SATAKE , Yuichiro HASHIMOTO
IPC分类号： H01J49/06 , H01J49/42
CPC分类号： H01J49/063 , H01J49/42
摘要： A first rod electrode set has a first center axis, into which ions and air current are introduced. A second rod electrode set has a second center axis at a distance from the first center axis, from which the ions are discharged. A power supply applies voltages to the first rod electrode set and the second rod electrode set. The first rod electrode set and the second rod electrode set have a region where the sets overlap each other in the longitudinal direction, and form a single multipole ion guide by being combined to each other in the region. Different offset DC voltages are applied to the first rod electrode set and the second rod electrode set, respectively, and a DC potential for moving the ions to the second rod electrode set in the region is formed, the ions having been guided by the first rod electrode set.

5. 发明申请

US20180261443A1 MASS SPECTROMETRY APPARATUS FOR ULTRAVIOLET LIGHT IONIZATION OF NEUTRAL LOST MOLECULES, AND METHOD FOR OPERATING SAME 审中-公开
公开(公告)号：US20180261443A1
公开(公告)日：2018-09-13
申请号：US15124382
申请日：2015-11-19
申请人： NATIONAL INSTITUTE OF METROLOGY CHINA
发明人： Xingchuang XIONG , Xiang FANG , You JIANG , Xiaoyun GONG , Zejian HUANG , Meiying LIU
IPC分类号： H01J49/42 , H01J49/00 , H01J49/16 , H01J49/36 , H01J49/04
CPC分类号： H01J49/4225 , H01J49/0031 , H01J49/0495 , H01J49/161 , H01J49/36 , H01J49/42
摘要： The invention proposes a mass spectrometry apparatus for ultraviolet light ionization of neutral lost molecules, and a method for operating same. The mass spectrometry apparatus for ultraviolet light ionization of neutral lost molecules includes a quadrupole tandem special linear ion trap mass analyzer, a vacuum ultraviolet lamp, a lamp front shutter, a gradient vacuum system and other necessary components for the mass spectrometry apparatus. In addition, the invention also proposes a method for operating the apparatus to efficiently store ions, fragment and analyze the ions, perform ultraviolet efficient ionization on lost neutral molecules, and then analyze the ions.

6. 发明授权

US09863914B2 Miniature quadrupole arrays using electron multiplication detectors 有权
公开(公告)号：US09863914B2
公开(公告)日：2018-01-09
申请号：US14808291
申请日：2015-07-24
申请人： Implant Sciences Corporation
发明人： Said Boumsellek
IPC分类号： G01N27/62 , H01J49/00 , H01J49/42
CPC分类号： G01N27/62 , H01J49/0009 , H01J49/0013 , H01J49/42 , H01J49/4215
摘要： A gas sensor includes a first chamber containing a plurality of evenly spaced rods having voltages applied thereto to cause gas ions in the first chamber to move in a direction from a first end of the first chamber to a second end of the first chamber and a second chamber coupled to the second end of the first chamber and having at least one ion detector, where ions pass from the first chamber to the second chamber through a plurality of channels between the first chamber and the second chamber and are detected by the at least one ion detector. The voltages applied to the rods may include a first voltage applied to a first subset of the rods and a second voltage applied to a second subset of the rods, each of first and second voltages containing a DC component and an AC component.

7. 发明授权

US09685310B2 System for recording spatial and temporal properties of ions emitted from a quadrupole mass filter 有权
公开(公告)号：US09685310B2
公开(公告)日：2017-06-20
申请号：US15088406
申请日：2016-04-01
申请人： Thermo Finnigan LLC
发明人： Johnathan Wayne Smith , Alan E. Schoen
IPC分类号： H01J49/02 , H01J49/00 , H01J49/42
CPC分类号： H01J49/0031 , H01J49/0036 , H01J49/025 , H01J49/42 , H01J49/4215 , H01J2237/24435
摘要： An ion detection system for a detecting a quantity of ions exiting from a mass analyzer of a mass spectrometer comprises: (a) photon generating means configured to receive the quantity of ions and to generate a quantity of photons that is proportional to the quantity of ions; (b) a linear array of photo-detectors configured along a line for detecting a variation of a portion of the quantity of generated photons along the line; and (c) an optical system for directing the portion of the quantity of photons from the photon generating means to the linear array of photo-detectors comprising: (c1) a first cylindrical lens having a first lens axis disposed parallel to the line; (c2) a second cylindrical lens or rod lens having a second lens axis disposed parallel to the line; and a doublet lens.

8. 发明申请

US20170152594A1 Method for Manufacturing Light-Emitting Element and Deposition Apparatus 审中-公开
公开(公告)号：US20170152594A1
公开(公告)日：2017-06-01
申请号：US15428625
申请日：2017-02-09
申请人： Semiconductor Energy Laboratory Co., Ltd.
发明人： Kohei Yokoyama , Hisao IKEDA , Shinichi HIRASA , Yasuhiro JINBO , Natsuko TAKASE
IPC分类号： C23C14/24 , H01L51/00 , A63F13/327 , H01J49/42 , H01J49/00 , C23C14/54 , H01L51/56
CPC分类号： C23C14/24 , A63F13/327 , C23C14/54 , C23C14/564 , F21S6/002 , F21Y2115/20 , H01J49/004 , H01J49/42 , H01L51/001 , H01L51/56 , H05B33/10
摘要： In order to provide a highly reliable organic EL element, a first step in which a deposition material is heated and vaporized in a deposition chamber in which the pressure is reduced and a second step in which a layer included in an EL layer is deposited in the deposition chamber are performed while exhaustion is performed and the partial pressure of water in the deposition chamber is measured with a mass spectrometer. Alternatively, the deposition chamber in the deposition apparatus includes a deposition material chamber and is connected to an exhaust mechanism. The deposition material chamber is separated from the deposition chamber by a sluice valve, includes a deposition material holding portion including a heating mechanism, and is connected to a mass spectrometer and an exhaust mechanism.

9. 发明授权

US09552974B2 Ion mobility separator with variable effective length 有权
标题翻译：具有可变有效长度的离子迁移分离器
公开(公告)号：US09552974B2
公开(公告)日：2017-01-24
申请号：US14751530
申请日：2015-06-26
申请人： Micromass UK Limited
发明人： Martin Raymond Green , David J. Langridge , Jason Lee Wildgoose
IPC分类号： B01D59/46 , B01D59/44 , H01J49/36 , G01N27/62 , H01J49/42 , H01J49/06
CPC分类号： H01J49/36 , G01N27/624 , H01J49/06 , H01J49/42 , H01J49/426
摘要： An ion mobility separator or spectrometer is disclosed comprising an inner cylinder and an outer cylinder defining an annular volume through which ions are transmitted. Spiral electrodes a-f are arranged on a surface of the inner cylinder and/or on a surface of the outer cylinder. A first device is arranged and adapted to maintain a DC electric field and/or a pseudo-potential force which acts to urge ions from a first end of the ion mobility separator or spectrometer to a second end of the ion mobility separator or spectrometer. A second device is arranged and adapted to apply transient DC voltages to the one or more spiral electrodes in order to urge ions towards the first end of the ion mobility separator or spectrometer. The net effect is to extend the effective path length of the ion mobility separator.
摘要翻译：公开了一种离子迁移率分离器或光谱仪，其包括限定通过离子传播的环形体积的内圆筒和外圆筒。螺旋电极a-f布置在内筒的表面上和/或外筒的表面上。第一装置被布置和适于维持DC电场和/或伪电势力，其用于将离子从离子迁移率分离器或光谱仪的第一端推动到离子迁移率分离器或光谱仪的第二端。第二装置被布置并适于将瞬态DC电压施加到一个或多个螺旋电极，以便促使离子朝向离子迁移率分离器或光谱仪的第一端。净效应是延长离子迁移率分离器的有效路径长度。

10. 发明申请

US20160217990A1 SYSTEM FOR RECORDING SPATIAL AND TEMPORAL PROPERTIES OF IONS EMITTED FROM A QUADRUPOLE MASS FILTER 有权
标题翻译：用于记录从四重质量过滤器发射的离子的空间和时间性质的系统
公开(公告)号：US20160217990A1
公开(公告)日：2016-07-28
申请号：US15088406
申请日：2016-04-01
申请人： Thermo Finnigan LLC
发明人： Johnathan Wayne SMITH , Alan E. SCHOEN
IPC分类号： H01J49/02 , H01J49/42
CPC分类号： H01J49/0031 , H01J49/0036 , H01J49/025 , H01J49/42 , H01J49/4215 , H01J2237/24435
摘要： An ion detection system for a detecting a quantity of ions exiting from a mass analyzer of a mass spectrometer comprises: (a) photon generating means configured to receive the quantity of ions and to generate a quantity of photons that is proportional to the quantity of ions; (b) a linear array of photo-detectors configured along a line for detecting a variation of a portion of the quantity of generated photons along the line; and (c) an optical system for directing the portion of the quantity of photons from the photon generating means to the linear array of photo-detectors comprising: (c1) a first cylindrical lens having a first lens axis disposed parallel to the line; (c2) a second cylindrical lens or rod lens having a second lens axis disposed parallel to the line; and a doublet lens.
摘要翻译：用于检测从质谱仪的质量分析器离开的离子的量的离子检测系统包括：（a）光子产生装置，被配置为接收离子的量并产生与离子量成比例的一定量的光子 ; （b）沿着一条线构成的光电检测器的线性阵列，用于检测沿线产生的光子的一部分的变化; （c）用于将来自光子发生装置的光子量的一部分引导到光电检测器的线性阵列的光学系统，包括：（c1）具有平行于该线设置的第一透镜轴的第一柱面透镜; （c2）具有平行于所述线布置的第二透镜轴的第二柱面透镜或棒状透镜; 和双头透镜。

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