专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US09494526B2 Combined illuminator/light collectors for optical readers 有权
标题翻译：用于光学读取器的组合照明器/光收发器
公开(公告)号：US09494526B2
公开(公告)日：2016-11-15
申请号：US13713595
申请日：2012-12-13
申请人： Step Ahead Innovations, Inc.
发明人： James E. Clark
IPC分类号： F21V5/00 , G01N21/88 , G01N21/77 , C02F1/00 , G01N33/18 , G01N21/85 , G01N21/15 , F21V8/00 , G01N21/78 , G01N31/22 , A01K63/04 , G01N21/64
CPC分类号： G01N21/77 , A01K63/04 , C02F1/008 , C02F2103/42 , C02F2209/005 , C02F2209/006 , C02F2209/008 , C02F2209/06 , C02F2209/14 , C02F2209/15 , C02F2209/18 , G01N21/15 , G01N21/6428 , G01N21/78 , G01N21/8507 , G01N21/88 , G01N31/22 , G01N33/18 , G01N2021/758 , G01N2021/7786 , G01N2021/7793 , G01N2201/127 , G02B6/0001 , Y10S436/805 , Y10S436/809 , Y10T436/11 , Y10T436/115831 , Y10T436/12 , Y10T436/173076 , Y10T436/173845 , Y10T436/174614 , Y10T436/175383 , Y10T436/193333 , Y10T436/207497 , Y10T436/25 , Y10T436/25375
摘要： Combined illuminator/light collectors (I/LCs) that provide measurement and/or reference light to a target and collect light from the target. One example of a use for a combined I/LC of the present disclosure is for an optic of an optical reader used to read one or more chemical indicators that undergo physical changes that can be optically detected. The combined I/LC includes a spot lensing designed and configured in conjunction with the target to provide spot illumination on the target from one or more light sources. A light collector collects light from the target resulting from the spot illumination. Some embodiments further include dispersive lensing to direct a portion of the light from each light source away from the spot illumination to keep that light from interfering with the spot illumination.
摘要翻译：组合的照明器/集光器（I / LC），其向目标提供测量和/或参考光并从目标收集光。用于本公开的组合I / LC的一个示例是用于读取一个或多个经历可被光学检测的物理变化的化学指示剂的光学读取器的光学元件。组合的I / LC包括与目标结合设计和配置的点透镜，以从一个或多个光源在目标上提供斑点照明。光收集器从点光照射中收集来自目标的光。一些实施例还包括色散透镜以将来自每个光源的光的一部分引导离开光点照明，以保持该光不影响光点照明。

2. 发明申请

US20140017143A1 Aquatic Environment Water-Quality Monitor Having A Submersible Chemical Indicator Wheel 有权
标题翻译：具有潜水化学指示轮的水环境水质监测仪
公开(公告)号：US20140017143A1
公开(公告)日：2014-01-16
申请号：US13713537
申请日：2012-12-13
申请人： Step Ahead Innovations, Inc.
发明人： James E. Clark
IPC分类号： G01N21/78
CPC分类号： G01N21/77 , A01K63/04 , C02F1/008 , C02F2103/42 , C02F2209/005 , C02F2209/006 , C02F2209/008 , C02F2209/06 , C02F2209/14 , C02F2209/15 , C02F2209/18 , G01N21/15 , G01N21/6428 , G01N21/78 , G01N21/8507 , G01N21/88 , G01N31/22 , G01N33/18 , G01N2021/758 , G01N2021/7786 , G01N2021/7793 , G01N2201/127 , G02B6/0001 , Y10S436/805 , Y10S436/809 , Y10T436/11 , Y10T436/115831 , Y10T436/12 , Y10T436/173076 , Y10T436/173845 , Y10T436/174614 , Y10T436/175383 , Y10T436/193333 , Y10T436/207497 , Y10T436/25 , Y10T436/25375
摘要： A water-quality monitoring system for an aquatic environment that includes a monitoring unit and a chemical indicator wheel designed and configured to be submerged in the water being monitored. The chemical indicator wheel includes a holder that supports a number of chemical indicators selected for use in measuring levels of constituents of the water. When in use, the wheel is drivingly engaged with a monitoring/measuring unit that includes at least one reader for reading the chemical indicators. In some embodiments, each apparatus includes a plurality of immobilized-dye-based chemical indicators that undergo an optically detectable physical change as levels of one or more constituents of the water change. Also disclosed are a variety of features that can be used to provide the monitoring system with additional functionalities.
摘要翻译：一种用于水环境的水质监测系统，包括监测单元和化学指示器轮，设计并配置为浸没在被监测的水中。化学指示轮包括支撑多个选择用于测量水分成分水平的化学指标的支架。在使用时，车轮与包含至少一个用于读取化学指示器的读取器的监测/测量单元驱动地接合。在一些实施方案中，每个装置包括多个基于固定化染料的化学指示剂，其随着水分变化的一个或多个成分的水平而经历可光学检测的物理变化。还公开了可用于向监控系统提供附加功能的各种特征。

3. 发明申请

US20140016122A1 Chemical Indicator Obstruction Detection System and Method For An Aquatic Environment 有权
标题翻译：化学指标障碍物检测系统和水环境的方法
公开(公告)号：US20140016122A1
公开(公告)日：2014-01-16
申请号：US13713668
申请日：2012-12-13
申请人： Step Ahead Innovations, Inc.
发明人： James E. Clark
IPC分类号： G01N21/88
CPC分类号： G01N21/77 , A01K63/04 , C02F1/008 , C02F2103/42 , C02F2209/005 , C02F2209/006 , C02F2209/008 , C02F2209/06 , C02F2209/14 , C02F2209/15 , C02F2209/18 , G01N21/15 , G01N21/6428 , G01N21/78 , G01N21/8507 , G01N21/88 , G01N31/22 , G01N33/18 , G01N2021/758 , G01N2021/7786 , G01N2021/7793 , G01N2201/127 , G02B6/0001 , Y10S436/805 , Y10S436/809 , Y10T436/11 , Y10T436/115831 , Y10T436/12 , Y10T436/173076 , Y10T436/173845 , Y10T436/174614 , Y10T436/175383 , Y10T436/193333 , Y10T436/207497 , Y10T436/25 , Y10T436/25375
摘要： A system and method for determining adverse conditions associated with a chemical indicator in an aquatic environment monitoring system in which reference illumination from an optical reader is used to illuminate a chemical indicator. Response from the reference illumination is used to determine a confidence value that can be part of an analysis associated with a measurement illumination response to produce a confidence adjustment instruction for possible action on the measured response value.
摘要翻译：一种用于确定与水中环境监测系统中的化学指示剂相关的不利条件的系统和方法，其中使用来自光学读取器的参考照明来照射化学指示剂。使用参考照明的响应来确定可以是与测量照明响应相关联的分析的一部分的置信度值，以产生对所测量的响应值的可能动作的置信度调整指令。

4. 发明授权

US08481324B2 Apparatus and methods for diagnosing renal disorders 有权
标题翻译：用于诊断肾脏疾病的装置和方法
公开(公告)号：US08481324B2
公开(公告)日：2013-07-09
申请号：US13131345
申请日：2009-12-02
申请人： Hossam Haick , Zaid Abassi , Farid Nakhoul
发明人： Hossam Haick , Zaid Abassi , Farid Nakhoul
IPC分类号： G01N33/48 , G01N27/04 , G01N27/22 , G01N1/22
CPC分类号： G01N33/497 , B82Y15/00 , G01N33/0034 , G01N2800/347 , Y10T436/145555 , Y10T436/172307 , Y10T436/173845 , Y10T436/174614 , Y10T436/200833 , Y10T436/25875
摘要： The present invention provides a system containing an array of chemically sensitive sensors based on coated single walled carbon nanotubes, for measuring volatile organic compounds indicative of renal failure. Methods of breath analysis for diagnosing chronic, acute and end-stage renal failure are disclosed.
摘要翻译：本发明提供一种包含基于涂覆的单壁碳纳米管的化学敏感传感器阵列的系统，用于测量指示肾衰竭的挥发性有机化合物。公开了用于诊断慢性，急性和终末期肾衰竭的呼吸分析方法。

5. 发明授权

US08158437B2 Luminescent detection of hydrazine and hydrazine derivatives 失效
标题翻译：肼和肼衍生物的发光检测
公开(公告)号：US08158437B2
公开(公告)日：2012-04-17
申请号：US12308298
申请日：2007-08-02
申请人： Timothy M. Swager , Samuel W. Thomas, III
发明人： Timothy M. Swager , Samuel W. Thomas, III
IPC分类号： G01N21/64 , G01N33/00
CPC分类号： G01N33/0057 , G01N2021/6432 , Y10T436/17 , Y10T436/173076 , Y10T436/173845 , Y10T436/174614 , Y10T436/175383
摘要： The present invention generally relates to methods for modulating the optical properties of a luminescent polymer via interaction with a species (e.g., an analyte). In some cases, the present invention provides methods for determination of an analyte by monitoring a change in an optical signal of a luminescent polymer upon exposure to an analyte. Methods of the present invention may be useful for the vapor phase detection of analytes such as explosives and toxins. The present invention also provides methods for increasing the luminescence intensity of a polymer, such as a polymer that has been photobleached, by exposing the luminescent polymer to a species such as a reducing agent.
摘要翻译：本发明一般涉及通过与物质（例如分析物）的相互作用来调节发光聚合物的光学性质的方法。在一些情况下，本发明提供了通过在暴露于分析物时监测发光聚合物的光学信号的变化来测定分析物的方法。本发明的方法可用于分析物如爆炸物和毒素的气相检测。本发明还提供了通过将发光聚合物暴露于诸如还原剂的物质来提高聚合物（例如已经漂白的聚合物）的发光强度的方法。

6. 发明申请

US20110244584A1 APPARATUS AND METHODS FOR DIAGNOSING RENAL DISORDERS 有权
标题翻译：用于诊断肾脏疾病的装置和方法
公开(公告)号：US20110244584A1
公开(公告)日：2011-10-06
申请号：US13131345
申请日：2009-12-02
申请人： Hossam Haick , Zaid Abassi , Farid Nakhoul
发明人： Hossam Haick , Zaid Abassi , Farid Nakhoul
IPC分类号： G01N33/92 , B01J19/00 , G01N33/64 , G01N33/50
CPC分类号： G01N33/497 , B82Y15/00 , G01N33/0034 , G01N2800/347 , Y10T436/145555 , Y10T436/172307 , Y10T436/173845 , Y10T436/174614 , Y10T436/200833 , Y10T436/25875
摘要： The present invention provides a system comprising an array of chemically sensitive sensors based on coated single walled carbon nanotubes, for measuring volatile organic compounds indicative of renal failure. Methods of breath analysis for diagnosing chronic, acute and end-stage renal failure are disclosed.
摘要翻译：本发明提供一种系统，其包括基于涂覆的单壁碳纳米管的化学敏感传感器阵列，用于测量指示肾衰竭的挥发性有机化合物。公开了用于诊断慢性，急性和终末期肾衰竭的呼吸分析方法。

7. 发明授权

US07981685B2 Generation of acyl amino acids 有权
标题翻译：产生酰基氨基酸
公开(公告)号：US07981685B2
公开(公告)日：2011-07-19
申请号：US12596272
申请日：2008-04-16
申请人： Kevin A. Jarrell , Prashanth Vishwanath , Gabriel Reznik
发明人： Kevin A. Jarrell , Prashanth Vishwanath , Gabriel Reznik
IPC分类号： C12P13/16 , C12P13/04
CPC分类号： C12N15/62 , C12N15/8243 , C12N15/8251 , C12N15/8257 , C12P13/02 , C12P13/04 , C12P13/14 , Y10T436/174614
摘要： Engineered polypeptides useful in synthesizing acyl amino acids are provided. Also provided are methods of making acyl amino acids using engineered polypeptides. In certain embodiments, an acyl amino acid produced using compositions and/or methods of the present invention comprises cocoyl glutamate.
摘要翻译：提供了可用于合成酰基氨基酸的工程化多肽。还提供了使用工程改造的多肽制备酰基氨基酸的方法。在某些实施方案中，使用本发明的组合物和/或方法产生的酰基氨基酸包括椰油酰谷氨酸。

8. 发明申请

US20110065202A1 Method for Examination of Alzheimer's Disease 审中-公开
标题翻译：阿尔茨海默病检查方法
公开(公告)号：US20110065202A1
公开(公告)日：2011-03-17
申请号：US12992309
申请日：2009-06-11
申请人： Khin Than Myint , Yoshiya Oda , Naoki Asai
发明人： Khin Than Myint , Yoshiya Oda , Naoki Asai
IPC分类号： G01N33/53 , G01N27/26 , G01N30/02 , H01J49/26
CPC分类号： G01N33/9453 , G01N30/72 , G01N33/9486 , G01N2800/2821 , Y10T436/174614
摘要： A method for examining Alzheimer's disease comprising (1) the measurement step of measuring an amount of lidocaine or a metabolite thereof in a cerebrospinal fluid derived from a lidocaine-administered test subject, and (2) the determination step of determining whether the test subject has Alzheimer's disease or not on the basis of the measured amount.
摘要翻译：一种检查阿尔茨海默氏病的方法，其特征在于，包括：（1）测定利多卡因或其代谢物在来自利多卡因的测试对象的脑脊液中的量的测定步骤，以及（2）阿尔茨海默氏病或不是基于测量量。

9. 发明授权

US07833799B2 Zwitterionic dyes for labeling in proteomic and other biological analyses 有权
标题翻译：用于在蛋白质组学和其他生物学分析中标记的两性离子染料
公开(公告)号：US07833799B2
公开(公告)日：2010-11-16
申请号：US11767404
申请日：2007-06-22
申请人： Edward A. Dratz , Paul A. Grieco
发明人： Edward A. Dratz , Paul A. Grieco
IPC分类号： G01N33/00 , G01N33/53
CPC分类号： C07F5/022 , G01N33/533 , G01N33/582 , Y10T436/173845 , Y10T436/174614
摘要： The invention relates to compositions and methods useful in the labeling and identification of proteins. The invention provides for highly soluble zwitterionic dye molecules where the dyes and associated side groups are non-titratable and maintain their net zwitterionic character over a broad pH range, for example, between pH 3 and 12. These dye molecules find utility in a variety of applications, including use in the field of proteomics.
摘要翻译：本发明涉及可用于标记和鉴定蛋白质的组合物和方法。本发明提供了高度可溶的两性离子染料分子，其中染料和相关侧基是不可滴定的并且在宽的pH范围（例如，pH 3和12）之间保持其净两性离子特征。这些染料分子可用于各种应用，包括在蛋白质组学领域的应用。

10. 发明申请

US20100285517A1 TRIMETHYLAMINE COMPOUNDS AS RISK PREDICTORS OF CARDIOVASCULAR DISEASE 有权
标题翻译：作为心血管疾病风险预防剂的三甲胺化合物
公开(公告)号：US20100285517A1
公开(公告)日：2010-11-11
申请号：US12746262
申请日：2008-12-05
申请人： Stanley L. Hazen , Zeneng Wang , Bruce S. Levison
发明人： Stanley L. Hazen , Zeneng Wang , Bruce S. Levison
IPC分类号： C12Q1/02 , G01N33/00
CPC分类号： G01N33/49 , G01N33/493 , G01N33/6893 , G01N33/92 , G01N2800/32 , G01N2800/323 , G01N2800/50 , G01N2800/52 , G01N2800/56 , H01J49/0036 , Y10T436/174614
摘要： Methods of characterizing a test subject's risk of having or developing cardiovascular disease are provided. The methods include using an analytic device to determine levels of choline-related trimethylamine-containing compounds such as trimethylamine N-oxide, choline, or betaine in a biological sample obtained from the subject and comparing the levels of the choline-related trimethylamine-containing compound in the subject's biological sample to a control value. The test subject's risk of having cardiovascular disease is then characterized as higher if the levels of the choline-related trimethylamine-containing compound are higher than the control value. Also provided are methods of identifying a subject at risk of experiencing a complication of atherosclerotic cardiovascular disease, and methods of evaluating the efficacy of a cardiovascular therapeutic agent in a subject with cardiovascular disease using levels of choline-related trimethylamine-containing compounds.
摘要翻译：提供测试受试者患有或发展心血管疾病风险的方法。所述方法包括使用分析装置来确定从受试者获得的生物样品中胆碱相关的含三甲胺的化合物如三甲胺N-氧化物，胆碱或甜菜碱的含量，并比较胆碱相关的含三甲胺的化合物在受试者的生物样本中达到对照值。如果胆碱相关的含三甲胺的化合物的含量高于对照值，则测试对象具有心血管疾病的风险的特征就更高。还提供了鉴定患有动脉粥样硬化性心血管疾病并发症风险的受试者的方法，以及使用胆碱相关的含三甲胺化合物水平的心血管疾病患者评价心血管治疗剂的功效的方法。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式