专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US10617665B2 Methods of therapeutic monitoring of nitrogen scavenging drugs 有权
公开(公告)号：US10617665B2
公开(公告)日：2020-04-14
申请号：US16194061
申请日：2018-11-16
申请人： Horizon Therapeutics, LLC
发明人： Bruce Scharschmidt , Masoud Mokhtarani
IPC分类号： A61K31/216 , A61K9/00 , G01N33/49 , A61K31/235 , G01N33/84 , G01N31/22
CPC分类号： A61K31/235 , A61K9/0053 , A61K31/216 , G01N31/221 , G01N33/4925 , G01N33/84 , G01N2800/04 , G01N2800/085 , G01N2800/52 , Y10T436/175383
摘要： The present disclosure provides methods for evaluating daily ammonia exposure based on a single fasting ammonia blood level measurement, as well as methods that utilize this technique to adjust the dosage of a nitrogen scavenging drug, determine whether to administer a nitrogen scavenging drug, and treat nitrogen retention disorders.

2. 发明申请

US20180021291A1 METHODS OF THERAPEUTIC MONITORING OF NITROGEN SCAVENGING DRUGS 有权
公开(公告)号：US20180021291A1
公开(公告)日：2018-01-25
申请号：US15687118
申请日：2017-08-25
申请人： Horizon Therapeutics, LLC
发明人： Bruce SCHARSCHMIDT , Masoud MOKHTARANI
IPC分类号： A61K31/235 , G01N33/84 , A61K31/216 , A61K9/00 , G01N31/22 , G01N33/49
CPC分类号： A61K31/235 , A61K9/0053 , A61K31/216 , G01N31/221 , G01N33/4925 , G01N33/84 , G01N2800/04 , G01N2800/085 , G01N2800/52 , Y10T436/175383
摘要： The present disclosure provides methods for evaluating daily ammonia exposure based on a single fasting ammonia blood level measurement, as well as methods that utilize this technique to adjust the dosage of a nitrogen scavenging drug, determine whether to administer a nitrogen scavenging drug, and treat nitrogen retention disorders.

3. 发明授权

US09494527B2 Optical reader optic cleaning systems having motion deployed cleaning elements 有权
标题翻译：具有运动部署清洁元件的光学读取器光学清洁系统
公开(公告)号：US09494527B2
公开(公告)日：2016-11-15
申请号：US13713864
申请日：2012-12-13
申请人： Step Ahead Innovations, Inc.
发明人： James E. Clark
IPC分类号： G01N21/15 , G01N21/88 , G01N21/77 , C02F1/00 , G01N33/18 , G01N21/85 , F21V8/00 , G01N21/78 , G01N31/22 , A01K63/04 , G01N21/64
CPC分类号： G01N21/77 , A01K63/04 , C02F1/008 , C02F2103/42 , C02F2209/005 , C02F2209/006 , C02F2209/008 , C02F2209/06 , C02F2209/14 , C02F2209/15 , C02F2209/18 , G01N21/15 , G01N21/6428 , G01N21/78 , G01N21/8507 , G01N21/88 , G01N31/22 , G01N33/18 , G01N2021/758 , G01N2021/7786 , G01N2021/7793 , G01N2201/127 , G02B6/0001 , Y10S436/805 , Y10S436/809 , Y10T436/11 , Y10T436/115831 , Y10T436/12 , Y10T436/173076 , Y10T436/173845 , Y10T436/174614 , Y10T436/175383 , Y10T436/193333 , Y10T436/207497 , Y10T436/25 , Y10T436/25375
摘要： Cleaning systems for optics of optical readers to periodically clean one or more surfaces of the optics of matter that may deposit on surface(s) and that might interfere with the performance of the reader. In an example, the cleaning system is used on a chemical indicator apparatus that includes one or more chemical indicators that are read by an optical reader having an optic. During use, the chemical indicator apparatus is moved relative optic during a reading mode. A cleaning element is engaged with the chemical indicator apparatus so as to have a neutral position in which it cannot contact the optic during the reading mode. When it is desired to clean the optic, the chemical indicator apparatus is moved in a manner that causes the cleaning element to move from the neutral position to a deployed position in which it contacts the optic in a manner that cleans the optic as the apparatus continues to be moved.
摘要翻译：用于光学读取器的光学系统的清洁系统周期性地清洁可能沉积在表面上并且可能干扰读取器的性能的物质光学元件的一个或多个表面。在一个示例中，清洁系统用于化学指示器装置，其包括由具有光学元件的光学读取器读取的一个或多个化学指示器。在使用期间，在读取模式期间，化学指示器装置相对于光学元件移动。清洁元件与化学指示器装置接合，以便具有在读取模式期间其不能接触光学元件的中性位置。当需要清洁光学元件时，化学指示器装置以使得清洁元件从中立位置移动到展开位置的方式移动，在该展开位置中，该化学指示器装置以与装置相连的方式清洁光学元件的方式移动被移动

4. 发明申请

US20160081969A1 METHODS OF THERAPEUTIC MONITORING OF NITROGEN SCAVENGING DRUGS 有权
公开(公告)号：US20160081969A1
公开(公告)日：2016-03-24
申请号：US14958259
申请日：2015-12-03
申请人： Horizon Therapeutics, Inc.
发明人： Bruce Scharschmidt , Masoud Mokhtarani
IPC分类号： A61K31/235 , A61K9/00
CPC分类号： A61K31/235 , A61K9/0053 , A61K31/216 , G01N31/221 , G01N33/4925 , G01N33/84 , G01N2800/04 , G01N2800/085 , G01N2800/52 , Y10T436/175383
摘要： The present disclosure provides methods for evaluating daily ammonia exposure based on a single fasting ammonia blood level measurement, as well as methods that utilize this technique to adjust the dosage of a nitrogen scavenging drug, determine whether to administer a nitrogen scavenging drug, and treat nitrogen retention disorders.

5. 发明授权

US09254278B2 Methods of therapeutic monitoring of nitrogen scavenging drugs 有权
公开(公告)号：US09254278B2
公开(公告)日：2016-02-09
申请号：US14816674
申请日：2015-08-03
申请人： Horizon Therapeutics, Inc.
发明人： Bruce Scharschmidt , Masoud Mokhtarani
IPC分类号： A61K49/00 , A61P13/00 , A61K31/216 , A61K9/00 , G01N31/22 , G01N33/49
CPC分类号： A61K31/235 , A61K9/0053 , A61K31/216 , G01N31/221 , G01N33/4925 , G01N33/84 , G01N2800/04 , G01N2800/085 , G01N2800/52 , Y10T436/175383
摘要： The present disclosure provides methods for evaluating daily ammonia exposure based on a single fasting ammonia blood level measurement, as well as methods that utilize this technique to adjust the dosage of a nitrogen scavenging drug, determine whether to administer a nitrogen scavenging drug, and treat nitrogen retention disorders.

6. 发明授权

US09095559B2 Methods of therapeutic monitoring of nitrogen scavenging drugs 有权
标题翻译：氮清除药物的治疗监测方法
公开(公告)号：US09095559B2
公开(公告)日：2015-08-04
申请号：US13775000
申请日：2013-02-22
申请人： Horizon Therapeutics, Inc.
发明人： Bruce Scharschmidt , Masoud Mokhtarani
IPC分类号： A61K49/00 , A61P13/00 , A61K31/216 , G01N31/22
CPC分类号： A61K31/235 , A61K9/0053 , A61K31/216 , G01N31/221 , G01N33/4925 , G01N33/84 , G01N2800/04 , G01N2800/085 , G01N2800/52 , Y10T436/175383
摘要： The present disclosure provides methods for evaluating daily ammonia exposure based on a single fasting ammonia blood level measurement, as well as methods that utilize this technique to adjust the dosage of a nitrogen scavenging drug, determine whether to administer a nitrogen scavenging drug, and treat nitrogen retention disorders.
摘要翻译：本公开内容提供了基于单次空腹氨血液测量来评估每日氨暴露的方法，以及利用该技术调节氮清除药物的剂量，确定是否施用清除氮气的药物并且治疗氮保留障碍。

7. 发明授权

US09063111B2 Hybrid chemical sensor, and, sensitive polymeric composition 有权
标题翻译：混合化学传感器，以及敏感聚合物组合物
公开(公告)号：US09063111B2
公开(公告)日：2015-06-23
申请号：US13001851
申请日：2009-06-22
申请人： Edwin Moncada Acevedo , Gilvan Pozzobon Pires , João Henrique Zimnoch Dos Santos
发明人： Edwin Moncada Acevedo , Gilvan Pozzobon Pires , João Henrique Zimnoch Dos Santos
IPC分类号： G01N31/22
CPC分类号： G01N31/221 , Y10T436/17 , Y10T436/173845 , Y10T436/175383
摘要： The present invention relates to chemical sensors with hybrid characteristics, which are thermo-mechanically stable and able to respond to changes in the environment, particularly in the presence of amine and/or amide and/or oxide-reducing compounds, and/or vapor thereof by color change, as well as its incorporation into sensitive polymeric composition.
摘要翻译：本发明涉及具有混合特性的化学传感器，其具有热机械稳定性并且能够响应环境变化，特别是在胺和/或酰胺和/或氧化物还原化合物和/或其蒸气存在下通过颜色变化，以及其结合到敏感聚合物组合物中。

8. 发明申请

US20150065365A1 THERMOELECTRIC SENSOR FOR ANALYTES IN A GAS AND RELATED METHOD 有权
标题翻译：用于气体分析的热电传感器及相关方法
公开(公告)号：US20150065365A1
公开(公告)日：2015-03-05
申请号：US14274844
申请日：2014-05-12
申请人： Invoy Technologies, L.L.C
发明人： Lubna Ahmad
IPC分类号： G01N33/64 , G01N33/98 , G01N33/497
CPC分类号： G01N33/497 , A61B5/097 , C12Q1/26 , C12Q1/54 , G01D1/06 , G01N15/0205 , G01N21/0332 , G01N21/3504 , G01N21/71 , G01N21/75 , G01N21/783 , G01N21/8483 , G01N25/00 , G01N25/20 , G01N25/4813 , G01N25/4873 , G01N27/26 , G01N31/22 , G01N31/224 , G01N33/4972 , G01N33/64 , G01N33/6893 , G01N33/98 , G01N2001/2223 , G01N2033/4975 , G01N2800/042 , G01N2800/347 , G01N2800/50 , Y10T436/172307 , Y10T436/175383 , Y10T436/196666 , Y10T436/200833 , Y10T436/202499 , Y10T436/203332 , Y10T436/204165 , Y10T436/212 , Y10T436/214
摘要： An apparatus is provided for sensing an analyte in a fluid. The apparatus includes a fluid collecting device configured to collect the fluid containing the analyte; a fluid input in fluid communication with the fluid collecting device configured to input the fluid containing the analyte into the fluid collecting device, an analyte interactant in fluid communication with the fluid collecting device, wherein the analyte interactant, when contacted by the analyte, reacts to cause a first change in thermal energy within the fluid collecting device; a modulator that causes a second change in thermal energy; a thermal sensing device comprising at least one pyroelectric device thermally coupled to the fluid collecting device to generate a first signal in response to at least one of the first change in thermal energy and the second change in thermal energy; a control device operatively coupled to the thermal sensing device and the modulator that generates a second signal, wherein the second signal comprises information useful in characterizing the analyte. A related method also is disclosed.
摘要翻译：提供了用于感测流体中的分析物的装置。该装置包括：流体收集装置，被配置为收集含有分析物的流体; 与所述流体收集装置流体连通的流体输入装置，其配置成将含有所述分析物的流体输入到所述流体收集装置中，所述分析物相互作用体与所述流体收集装置流体连通，其中所述分析物相互作用体在被所述分析物接触时反应引起流体收集装置内热能的第一变化; 导致热能的第二变化的调制器; 热感测装置，其包括热耦合到所述流体收集装置的至少一个热电装置，以响应于热能的第一变化和第二热能变化中的至少一个而产生第一信号; 控制装置，其可操作地耦合到所述热感测装置和所述调制器，所述调制器产生第二信号，其中所述第二信号包括用于表征所述分析物的信息。还公开了相关方法。

9. 发明授权

US08940543B2 Diagnostic tool and process for assessing thermal urea gasification performance 有权
标题翻译：用于评估热尿素气化性能的诊断工具和过程
公开(公告)号：US08940543B2
公开(公告)日：2015-01-27
申请号：US13463634
申请日：2012-05-03
申请人： William H. Sun , John M. Boyle
发明人： William H. Sun , John M. Boyle
IPC分类号： C01C3/14 , F23J15/00 , F23N5/00 , C01C1/02 , C01C1/08
CPC分类号： C01C1/086 , C01C3/145 , F23J15/003 , F23J15/006 , F23J2215/50 , F23J2217/50 , F23J2219/10 , F23N5/003 , Y10T436/175383
摘要： Disclosed are methods and apparatus for treating and analyzing a gas stream to determine the effectiveness of urea gasification. The apparatus will be capable of performing the method and will include: means for introducing an aqueous solution of urea into a reactor having hot gases therein and subjecting the aqueous to temperatures for a time to assure the gasification of the aqueous urea and form a thermal gasification product stream containing NH3 and HNCO; means for taking a sample stream from the gasification product stream; means for contacting the sample stream with a hydrolysis catalyst in the presence of sufficient water to convert HNCO to NH3 and form an ammonia sample stream; and means for analyzing the ammonia sample stream for NH3. The methods and apparatus can also be used to control a urea gasification process and/or to signal anomalous operation.
摘要翻译：公开了用于处理和分析气流以确定尿素气化的有效性的方法和装置。该设备将能够执行该方法，并且将包括：用于将尿素水溶液引入其中具有热气体的反应器中的装置，并使水温持续一段时间以确保尿素水溶液的气化并形成热气化含NH3和HNCO的产品流; 用于从气化产物流中取样品流的装置; 用于在足够的水存在下使样品流与水解催化剂接触以将HNCO转化成NH 3并形成氨样品流的装置; 以及用于分析NH 3的氨样品流的装置。该方法和设备也可用于控制尿素气化过程和/或发出异常操作信号。

10. 发明申请

US20130157377A1 AMMONIA COMPOUND CONCENTRATION MEASURING DEVICE AND AMMONIA COMPOUND CONCENTRATION MEASURING METHOD 有权
标题翻译：氨络合物浓度测定装置及氨化合物浓度测定方法
公开(公告)号：US20130157377A1
公开(公告)日：2013-06-20
申请号：US13806477
申请日：2010-09-28
申请人： Atsushi Takita , Masazumi Tanoura , Kenji Muta , Shinichiro Asami , Kageharu Moriyama
发明人： Atsushi Takita , Masazumi Tanoura , Kenji Muta , Shinichiro Asami , Kageharu Moriyama
IPC分类号： G01N21/59
CPC分类号： G01N21/59 , G01N1/2247 , G01N21/3504 , G01N21/359 , G01N33/0054 , Y02A50/246 , Y10T436/17 , Y10T436/175383 , Y10T436/25875
摘要： An ammonia compound concentration measuring device includes: a pipe unit through which the circulating gas flows; a converter which is disposed in the pipe unit and converts an ammonia compound into ammonia; a measurement device which measures a first measurement value as a concentration of ammonia contained in a first circulating gas flowing inside a pipe line passing through the converter in the circulating gas flowing inside the pipe unit and a second measurement value as a concentration of ammonia contained in a second circulating gas flowing inside a pipe line not passing through the converter in the circulating gas flowing inside the pipe unit; and a controller which controls operations of the pipe unit and the measurement device and calculates the concentration of the ammonia compound of the measurement subject contained in the circulating gas from a difference between the first measurement value and the second measurement value.
摘要翻译：氨化合物浓度测定装置包括：循环气体流过的管道单元; 转换器，其设置在管单元中并将氨化合物转化为氨; 测量装置，其测量第一测量值作为流经管单元内的循环气体中通过转换器的管线内流动的第一循环气体中所含的氨的浓度，以及作为包含在第二测量值中的氨的浓度的第二测量值流经管单元内的循环气体中不流经转换器的管路内的第二循环气体; 以及控制器，其控制管单元和测量装置的操作，并且从第一测量值和第二测量值之间的差计算循环气体中包含的测量对象的氨化合物的浓度。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式