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1. 发明授权

US09610367B2 Particle and contrast agent having the particle 有权
公开(公告)号：US09610367B2
公开(公告)日：2017-04-04
申请号：US13817711
申请日：2011-08-23
申请人： Shinzaburo Ito , Masato Minami , Tatsuki Fukui , Kouichi Kato , Fumio Yamauchi , Yoshinori Tomida , Satoshi Yuasa , Tetsuya Yano , Satoshi Ogawa , Kengo Kanazaki , Atsushi Takahashi , Daisuke Sasaguri , Hiroyuki Aoki
发明人： Shinzaburo Ito , Masato Minami , Tatsuki Fukui , Kouichi Kato , Fumio Yamauchi , Yoshinori Tomida , Satoshi Yuasa , Tetsuya Yano , Satoshi Ogawa , Kengo Kanazaki , Atsushi Takahashi , Daisuke Sasaguri , Hiroyuki Aoki
IPC分类号： A61K9/00 , A61K49/00 , A61K9/51 , A61K49/22 , B82Y15/00 , B82Y30/00
CPC分类号： A61K49/0093 , A61K9/5153 , A61K49/0034 , A61K49/0052 , A61K49/225 , B82Y15/00 , B82Y30/00
摘要： There is provided an ICG-loaded polymer nanoparticle that is dynamically stable, prevents the leakage of contained ICG and the resulting discoloration, and has a high molar absorbance coefficient. The particle contains a hydrophilic dye having a sulfonate group and a hydrophobic polymer, and the particle further contains at least one of a lipid having a positively charged region, a nicotinic acid derivative and a thiamine derivative.

2. 发明申请

US20110081294A1 CONTRAST AGENT FOR PHOTOACOUSTIC IMAGING AND PHOTOACOUSTIC IMAGING METHOD 有权
标题翻译：对比成像和光电成像方法
公开(公告)号：US20110081294A1
公开(公告)日：2011-04-07
申请号：US12893074
申请日：2010-09-29
申请人： Tatsuki Fukui , Fumio Yamauchi , Satoshi Yuasa , Sachiko Inoue
发明人： Tatsuki Fukui , Fumio Yamauchi , Satoshi Yuasa , Sachiko Inoue
IPC分类号： A61K49/00 , C07D209/04 , C09B5/00 , C07D209/58 , A61P43/00
CPC分类号： C07D209/58 , A61K41/00 , A61K49/0032 , A61K49/0036 , A61K49/0093 , C07D209/60 , C07D209/62 , C07D487/22 , C09B23/0033 , C09B23/0066 , C09B23/086 , C09B47/0673
摘要： A method of detecting a contrast agent for photoacoustic imaging provides a high signal intensity. In a contrast agent for photoacoustic imaging, each particle containing an inorganic material supports at least an organic dye having an absorption coefficient in the near infrared region by means of chemical bonding.
摘要翻译：检测光声成像造影剂的方法提供高信号强度。在用于光声成像的造影剂中，含有无机材料的每个颗粒通过化学键合至少支持在近红外区域具有吸收系数的有机染料。

3. 发明授权

US06906851B2 Electrophoretic display device and method of producing the same 失效
标题翻译：电泳显示装置及其制造方法
公开(公告)号：US06906851B2
公开(公告)日：2005-06-14
申请号：US10448189
申请日：2003-05-30
申请人： Satoshi Yuasa
发明人： Satoshi Yuasa
IPC分类号： G02F1/167 , G02B26/00 , G01R1/12 , G03G17/04 , G09G3/34
CPC分类号： G02F1/167
摘要： An electrophoretic display device executes a display on the basis of dispersing charged particles in a liquid and moving the charged particles under application of an electric field. The device includes a first substrate having an electrode, a film mounted on the first substrate and forming a closed portion with a surface of the first substrate, and a liquid positioned in the closed portion, with charged particles being dispersed in the liquid.
摘要翻译：电泳显示装置基于将带电粒子分散在液体中并在施加电场的状态下移动带电粒子来执行显示。该装置包括具有电极的第一基板，安装在第一基板上的膜，并且形成具有第一基板的表面的封闭部分，以及位于封闭部分中的液体，带电粒子分散在液体中。

4. 发明授权

US06270389B1 Method for forming an electron-emitting device using a metal-containing composition 有权
标题翻译：使用含金属组合物形成电子发射器件的方法
公开(公告)号：US06270389B1
公开(公告)日：2001-08-07
申请号：US09584291
申请日：2000-05-31
申请人： Shin Kobayashi , Tsuyoshi Furuse , Satoshi Yuasa , Naoko Miura , Takashi Iwaki , Yasuko Tomida
发明人： Shin Kobayashi , Tsuyoshi Furuse , Satoshi Yuasa , Naoko Miura , Takashi Iwaki , Yasuko Tomida
IPC分类号： H01J900
CPC分类号： H01J1/316 , H01J2329/00
摘要： A method of manufacturing an electron-emitting device that has an electroconductive film containing an electron-emitting region disposed between a pair of device electrodes includes a process of forming the electroconductive film by the steps of (a) applying a metal-containing solution, and (b) heating the solution. The metal-containing solution comprises a compound containing an organic acid group, a transition metal and an alcohol amine, and water.
摘要翻译：制造具有包含设置在一对器件电极之间的电子发射区的导电膜的电子发射器件的方法包括通过以下步骤形成导电膜的工艺：（a）施加含金属溶液，以及（b）加热溶液。含金属的溶液包含含有机酸基，过渡金属和醇胺的化合物和水。

5. 发明授权

US5911866A Acid tin-silver alloy electroplating bath and method for electroplating tin-silver alloy 失效
标题翻译：酸性锡 - 银合金电镀浴和电镀锡 - 银合金的方法
公开(公告)号：US5911866A
公开(公告)日：1999-06-15
申请号：US921081
申请日：1997-08-29
申请人： Katsuhide Oshima , Satoshi Yuasa
发明人： Katsuhide Oshima , Satoshi Yuasa
IPC分类号： C25D3/56 , C25D3/60 , C25D3/46 , C23C18/00
CPC分类号： C25D3/60
摘要： The invention relates to an acid tin-silver alloy plating bath which comprises tin ions, silver ions, one compound selected from the group consisting of aromatic thiol compounds and aromatic sulfide compounds, substantially non-cyanide and a balance of water, the pH of the bath being not higher than 2. According to this acid bath, tin and silver can be kept dissolved in the bath in a stable state for a long period of time even at a high temperature and a predetermined plating capacity is kept for a long period of time even though the bath is free from cyanide.
摘要翻译：本发明涉及一种酸性锡 - 银合金电镀液，其包含锡离子，银离子，选自芳族硫醇化合物和芳族硫化物化合物的一种化合物，基本上不含氰化物和余量的水，浴不高于2.根据该酸浴，即使在高温下，锡和银也可以长时间稳定地溶解在浴中，长时间保持预定的电镀能力即使洗澡没有氰化物。

6. 发明授权

US5840716A Phosphonate nucleotide compounds 失效
标题翻译：磷酸核苷酸化合物
公开(公告)号：US5840716A
公开(公告)日：1998-11-24
申请号：US785606
申请日：1997-01-17
申请人： Masaru Ubasawa , Kouichi Sekiya , Hideaki Takashima , Naoko Ueda , Satoshi Yuasa , Naohiro Kamiya
发明人： Masaru Ubasawa , Kouichi Sekiya , Hideaki Takashima , Naoko Ueda , Satoshi Yuasa , Naohiro Kamiya
IPC分类号： C07F9/6561 , A01N57/00 , C07F9/02
CPC分类号： C07F9/6561 , C07F9/65616
摘要： A phosphonate nucleotide compound having antiviral activity and is useful for an orally available and highly safe antiviral agent, which is represented by the following formula (I): ##STR1## wherein R.sup.1 represents hydrogen, a C.sub.1 -C.sub.6 alkoxy, a halogen-substituted C.sub.1 -C.sub.4 alkoxy, halogen, amino, or nitro; R.sup.2 and R.sup.3 independently represent hydrogen, a C.sub.1 -C.sub.22 alkyl, an acyloxymethy, an acylthioethyl, or a halogen-substituted ethyl; R.sup.4 represents hydrogen, a C.sub.1 -C.sub.4 alkyl, a C.sub.1 -C.sub.4 hydroxyalkyl, or a halogen-substituted C.sub.1 -C.sub.4 alkyl; and X represents carbon or nitrogen.
摘要翻译：具有抗病毒活性的膦酸酯核苷酸化合物，可用于口服可用和高度安全的抗病毒剂，其由下式（I）表示：其中R 1表示氢，C 1 -C 6烷氧基，卤素取代的C 1 -C 4烷氧基，卤素，氨基或硝基; R2和R3独立地表示氢，C1-C22烷基，酰氧基甲基，酰基硫代乙基或卤素取代的乙基; R4表示氢，C1-C4烷基，C1-C4羟基烷基或卤素取代的C1-C4烷基; X表示碳或氮。

7. 发明授权

US5604209A Synergistic antiviral compositions 失效
标题翻译：协同抗病毒组合物
公开(公告)号：US5604209A
公开(公告)日：1997-02-18
申请号：US253274
申请日：1994-06-02
申请人： Masaru Ubasawa , Satoshi Yuasa
发明人： Masaru Ubasawa , Satoshi Yuasa
IPC分类号： A61K31/505 , A61K31/52 , A61K31/66 , A61K31/70 , A61P31/12 , A61P31/18
CPC分类号： A61K31/70 , Y10S514/885
摘要： Antiviral agents which comprises as active ingredients one or more 2',3'-dideoxyribonucleosides or phosphoric esters thereof and 6-benzyl-1-ethoxymethyl-5-substituted uracil derivative of the formula (I): ##STR1## wherein X is oxygen or sulfur atom; R.sup.1 is ethyl or isopropyl; R.sup.2 and R.sup.3 are independently hydrogen atom, C.sub.1 -C.sub.3 alkyl or halogen atom, which compounds can inhibit HIV reverse transcriptase through different mechanisms and are synergistic in combination.
摘要翻译：包含作为活性成分的一种或多种2'，3'-脱氧核糖核苷或其磷酸酯和式（I）的6-苄基-1-乙氧基甲基-5-取代的尿嘧啶衍生物的抗病毒剂：其中X 是氧或硫原子; R1是乙基或异丙基; R2和R3独立地是氢原子，C1-C3烷基或卤原子，这些化合物可以通过不同的机理抑制HIV逆转录酶，并且是组合的协同作用。

8. 发明授权

US5523871A Liquid crystal device having a uniaxial alignment polymer film with at least two species of dopants 失效
标题翻译：具有具有至少两种掺杂剂的单轴取向聚合物膜的液晶装置
公开(公告)号：US5523871A
公开(公告)日：1996-06-04
申请号：US253290
申请日：1994-06-03
申请人： Masaaki Shibata , Etsuro Kishi , Satoshi Yuasa
发明人： Masaaki Shibata , Etsuro Kishi , Satoshi Yuasa
IPC分类号： G02F1/1337 , G02F1/141
CPC分类号： G02F1/1418 , G02F1/133711 , G02F2202/06
摘要： A liquid crystal device is constituted by a pair of substrates each having thereon an electrode and a uniaxial alignment film, and a chiral smectic liquid crystal disposed between the substrates. At least one of the uniaxial alignment films is a film comprising an electroconductive polymer doped with at least two species of dopants, which preferably include a first type dopant capable of dedoping into the liquid crystal due to electric field application or diffusion, and a second type dopant substantially incapable of dedoping into the liquid crystal. The resultant liquid crystal device is alleviated with respect to voltage hysteresis and is suitable for gradational display.
摘要翻译：液晶装置由分别具有电极和单轴取向膜的一对基板和设置在基板之间的手性近晶液晶构成。单轴取向膜中的至少一个是包含掺杂有至少两种掺杂剂的导电性聚合物的膜，其优选包括能够由于电场施加或扩散而能够掺杂到液晶中的第一种掺杂剂，第二类型掺杂剂基本上不能去掺杂到液晶中。所得到的液晶装置相对于电压滞后而减轻，并且适合于梯度显示。

9. 发明申请

US20150125708A1 SURFACE-TREATING AQUEOUS SOLUTION AND TREATMENT METHODS FOR FORMING CORROSION-RESISTANT COATING FILM OVER ZINC OR ZINC ALLOY DEPOSIT 审中-公开
标题翻译：表面处理水溶液和处理方法，用于在锌或锌合金沉积物上形成耐腐蚀涂层膜
公开(公告)号：US20150125708A1
公开(公告)日：2015-05-07
申请号：US14591049
申请日：2015-01-07
申请人： Hitoshi Sakurai , Satoshi Yuasa , Keisuke Nonomura
发明人： Hitoshi Sakurai , Satoshi Yuasa , Keisuke Nonomura
IPC分类号： C23C22/05
摘要： A chromium-free treating liquid and treatment methods which are for imparting to a zinc or zinc alloy deposit a coating film which is highly corrosion-resistant, has a uniform appearance free from sag stains/puddle stains, has no failure concerning thickness unevenness, and has satisfactory adhesion. The surface-treating aqueous solution, which is for forming a corrosion-resistant coating film over a zinc or zinc alloy deposit, is characterized by comprising (a) an alkali metal silicate (M2O.nSiO2 (wherein M represents an alkali metal and n indicates SiO2/M2O molar ratio)), (b) a water-soluble or water-dispersible silane coupling agent, and (c) a water-soluble or water-dispersible glycidyl ether compound. One of the surface treatment methods for forming a highly corrosion-resistant coating film over a zinc or zinc alloy deposit includes bringing the surface of the zinc or zinc alloy deposit into contact with the surface-treating aqueous solution. The surface-treating aqueous solution is applicable also to the surface of a chemical conversion coating film formed on a zinc or zinc alloy deposit and free from hexavalent chromium or from chromium in any form. Namely, another surface treatment method for forming a highly corrosion-resistant coating film over a zinc or zinc alloy deposit comprises bringing the surface of a chemical conversion coating film formed on a zinc or zinc alloy deposit into contact with the surface-treating aqueous solution. Furthermore provided is a highly corrosion-resistant coating film formed by bringing the solution into contact with the surface of a zinc or zinc alloy deposit or with the surface of a chemical conversion coating film formed on a zinc or zinc alloy deposit.
摘要翻译：无铬处理液和用于赋予锌或锌合金的处理方法沉积具有高耐腐蚀性的涂膜，具有没有凹陷污渍/水泥污渍的均匀外观，对于厚度不均匀性没有失败，并且具有令人满意的粘合力。用于在锌或锌合金沉积物上形成耐腐蚀涂膜的表面处理水溶液的特征在于包含（a）碱金属硅酸盐（M 2 O·nSiO 2（其中M表示碱金属，n表示 SiO 2 / M 2 O摩尔比）），（b）水溶性或水分散性硅烷偶联剂，和（c）水溶性或水分散性缩水甘油醚化合物。在锌或锌合金沉积物上形成高耐腐蚀涂膜的表面处理方法之一包括使锌或锌合金沉积物的表面与表面处理水溶液接触。表面处理水溶液也可用于形成于锌或锌合金沉积物上且不含六价铬或以任何形式的铬形成的化学转化膜的表面。也就是说，用于在锌或锌合金沉积物上形成高耐腐蚀涂膜的另一种表面处理方法包括使形成在锌或锌合金沉积物上的化学转化膜的表面与表面处理水溶液接触。此外，还提供了通过使溶液与锌或锌合金沉积物的表面或与锌或锌合金沉积物上形成的化学转化膜的表面接触而形成的高度耐腐蚀的涂膜。

10. 发明申请

US20120052011A1 COMPOSITION AND A METHOD FOR PRODUCING CONTRAST AGENT USING THE COMPOSITION 审中-公开
标题翻译：组合物和使用该组合物生产对比剂的方法
公开(公告)号：US20120052011A1
公开(公告)日：2012-03-01
申请号：US13205246
申请日：2011-08-08
申请人： Tatsuki Fukui , Satoshi Yuasa , Kouichi Kato
发明人： Tatsuki Fukui , Satoshi Yuasa , Kouichi Kato
IPC分类号： A61K49/00 , A61P43/00
CPC分类号： A61K49/0034 , A61K49/0032
摘要： A composition including a hydrophilic dye having a sulfonate group and a hydrophobic solvent, wherein the composition includes at least one of a nicotinic acid derivative and a tiamine derivative, can form densely accumulated particles and the like since the composition includes a hydrophilic dye that is likely to dissolve in a hydrophobic solvent.
摘要翻译：包含具有磺酸盐基团和疏水性溶剂的亲水性染料的组合物，其中所述组合物包含烟酸衍生物和硫胺素衍生物中的至少一种可以形成致密聚集的颗粒等，因为该组合物包含可能的亲水性染料溶解在疏水性溶剂中。

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