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1. 发明授权

US09135116B1 Cloud enabled filesystems provided by an agent which interfaces with a file system on a data source device 有权
标题翻译：由与数据源设备上的文件系统接口的代理提供的启用云的文件系统
公开(公告)号：US09135116B1
公开(公告)日：2015-09-15
申请号：US13248389
申请日：2011-09-29
申请人： Shankar Balasubramanian , Anil Degwekar , Srinivasan Ramachandran , Anand Raj , Deepak Visweswaraiah
发明人： Shankar Balasubramanian , Anil Degwekar , Srinivasan Ramachandran , Anand Raj , Deepak Visweswaraiah
IPC分类号： G06F17/30 , G06F3/06 , G06F11/14
CPC分类号： G06F11/1435 , G06F3/061 , G06F3/0635 , G06F3/0647 , G06F3/067 , G06F11/1448 , G06F17/30091
摘要： Information is managed by receiving at a data source device, from an application running on a data source device, an instruction associated with a file system object. It is determined at the data source device if the instruction is able to be satisfied by a file system running on the data source device. If it is determined that the instruction is not able to be satisfied by the file system, the instruction is performed without the services of the file system; the application is unaware that the file system object is managed by an entity other than the file system running on the data source device.
摘要翻译：通过在数据源设备上从在数据源设备上运行的应用接收与文件系统对象相关联的指令来管理信息。在数据源设备中确定是否能够由在数据源设备上运行的文件系统来满足该指令。如果确定文件系统不能满足该指令，则在没有文件系统的服务的情况下执行指令; 应用程序不知道文件系统对象由除数据源设备上运行的文件系统之外的实体管理。

2. 发明申请

US20120202196A1 LABELLED NUCLEOTIDES 有权
公开(公告)号：US20120202196A1
公开(公告)日：2012-08-09
申请号：US13432989
申请日：2012-03-28
申请人： Shankar Balasubramanian , Colin Barnes , Xiaohai Liu , John Milton
发明人： Shankar Balasubramanian , Colin Barnes , Xiaohai Liu , John Milton
IPC分类号： C12Q1/68 , G01N21/76 , C12P19/34
CPC分类号： C12Q1/6869 , C07H19/10 , C07H19/20 , C07H21/00 , C12P19/34 , C12Q1/6806 , C12Q1/6818 , C12Q1/6823 , C12Q1/6834 , C12Q1/6874 , C12Q1/6876 , C12Q2525/186
摘要： Nucleosides and nucleotides are disclosed that are linked to detectable labels via a cleavable linker group.

3. 发明申请

US20120184457A1 Modulation of miRNA Activity 审中-公开
标题翻译：调节miRNA活性
公开(公告)号：US20120184457A1
公开(公告)日：2012-07-19
申请号：US13389159
申请日：2010-08-06
申请人： Eric Miska , Nicolas Lehrbach , Javier Armisen-Garrido , Shankar Balasubramanian
发明人： Eric Miska , Nicolas Lehrbach , Javier Armisen-Garrido , Shankar Balasubramanian
IPC分类号： G01N33/53 , C12Q1/68 , C40B30/04
CPC分类号： C12Q1/485 , G01N33/573 , G01N2333/9125 , G01N2500/02
摘要： Provided is a method of identifying a compound which modulates miRNA activity comprising (i) determining the ability of a test compound to alter the polyuridylation activity of a ZCCHC polypeptide wherein a test compound which alters the polyuridylation activity is useful in modulating miRNA activity; or (ii) determining the ability of a test compound to alter the binding of a ZCCHC polypeptide to a LIN28 polypeptide, wherein a test compound which alters said binding may be useful in modulating miRNA activity; or (iii) determining the ability of a test compound to bind to a ZCCHC polypeptide, wherein a test compound which binds to the ZCCHC polypeptide may be useful in modulating miRNA activity.
摘要翻译：提供了鉴定调节miRNA活性的化合物的方法，其包括（i）测定测试化合物改变ZCCHC多肽的多聚尿苷酸化活性的能力，其中改变多聚尿苷酸化活性的测试化合物可用于调节miRNA活性; 或（ii）测定测试化合物改变ZCCHC多肽与LIN28多肽的结合的能力，其中改变所述结合的测试化合物可用于调节miRNA活性; 或（iii）测定测试化合物结合ZCCHC多肽的能力，其中与ZCCHC多肽结合的测试化合物可用于调节miRNA活性。

4. 发明授权

US08148064B2 Labelled nucleotides 有权
标题翻译：标记核苷酸
公开(公告)号：US08148064B2
公开(公告)日：2012-04-03
申请号：US12804296
申请日：2010-07-19
申请人： Shankar Balasubramanian , Colin Barnes , Xiaohai Liu , John Milton
发明人： Shankar Balasubramanian , Colin Barnes , Xiaohai Liu , John Milton
IPC分类号： C12Q1/68 , C12P19/34 , C07H21/00 , C07H21/02
CPC分类号： C12Q1/6869 , C07H19/10 , C07H19/20 , C07H21/00 , C12P19/34 , C12Q1/6806 , C12Q1/6818 , C12Q1/6823 , C12Q1/6834 , C12Q1/6874 , C12Q1/6876 , C12Q2525/186
摘要： Nucleosides and nucleotides are disclosed that are linked to detectable labels via a cleavable linker group.
摘要翻译：公开了通过可切割连接基团与可检测标记物连接的核苷和核苷酸。

5. 发明申请

US20100028960A1 Preparation of Precisely Controlled Thin Film Nanocomposite of Carbon Nanotubes and Biomaterials 审中-公开
标题翻译：制备碳纳米管和生物材料的精确控制薄膜纳米复合材料
公开(公告)号：US20100028960A1
公开(公告)日：2010-02-04
申请号：US12261892
申请日：2008-10-30
申请人： Virginia A. Davis , Aleksandr L. Simonian , Dhriti Nepal , Shankar Balasubramanian
发明人： Virginia A. Davis , Aleksandr L. Simonian , Dhriti Nepal , Shankar Balasubramanian
IPC分类号： C12P9/00 , B32B9/00 , B05D1/36 , A61L2/00
CPC分类号： B82Y5/00 , A01N37/46 , A01N57/16 , Y10T428/265 , A01N25/10 , A01N25/34 , A01N2300/00
摘要： Disclosed are nanocomposite materials comprising multiple layers of biomolecules bound to aligned carbon nanotubes. The thickness of each of the layers may be precisely controlled using a layer-by-layer assembly technique.
摘要翻译：公开了纳米复合材料，其包含结合到对准的碳纳米管的多层生物分子。可以使用逐层组装技术来精确地控制每个层的厚度。

6. 发明申请

US20060248299A1 FABRIC WITH FIBRE CHANNEL FABRIC SNAPSHOT SERVICE 失效
标题翻译：织物与纤维通道织物快速服务
公开(公告)号：US20060248299A1
公开(公告)日：2006-11-02
申请号：US11457757
申请日：2006-07-14
申请人： BALAKUMAR KAUSHIK , SHANKAR BALASUBRAMANIAN , RICHARD HAMMONS
发明人： BALAKUMAR KAUSHIK , SHANKAR BALASUBRAMANIAN , RICHARD HAMMONS
IPC分类号： G06F12/16
CPC分类号： G06F11/1464 , G06F11/1466 , G06F2201/84 , H04L49/357 , H04L67/1097 , Y10S707/99953 , Y10S707/99955
摘要： The snapshot capability moving into the SAN fabric and being provided as a snapshot service. A well-known address is utilized to receive snapshot commands. Each switch in the fabric connected to a host contains a front end or service interface to receive the snapshot command. Each switch of the fabric connected to a storage device used in the snapshot process contains a write interceptor module which cooperates with hardware in the switch to capture any write operations which would occur to the snapshot data area. The write interceptor then holds these particular write operations until the original blocks are transferred to a snapshot or separate area so that the original read data is maintained. Should a read operation occur to the snapshot device and the original data from requested location has been relocated, a snapshot server captures these commands and redirects the read operation to occur from the snapshot area. If, however, the read operation is directed to the original drive, the read is provided from the original data areas, even if the data had been replaced. The snapshot server determines the existence of particular snapshot devices, allocates their storage locations, provides this information to both the service interfaces and the write interceptors and handles read and write operations to the snapshot device.
摘要翻译：快照功能进入SAN架构，并作为快照服务提供。利用着名的地址接收快照命令。连接到主机的每个交换机都包含一个前端或服务接口来接收快照命令。连接到快照过程中使用的存储设备的结构的每个交换机都包含一个写入拦截器模块，该模块与交换机中的硬件配合，以捕获快照数据区域将发生的任何写入操作。写拦截器然后保存这些特定的写入操作，直到原始块被传送到快照或分离区域，以便保持原始读取数据。如果快照设备发生读取操作，并且重新定位了来自请求位置的原始数据，则快照服务器捕获这些命令并重定向从快照区域发生的读取操作。但是，如果读取操作指向原始驱动器，则即使已更换数据，也会从原始数据区域提供读取。快照服务器确定特定快照设备的存在，分配其存储位置，将此信息提供给服务接口和写截取器，并处理对快照设备的读写操作。

7. 发明申请

US20060188901A1 Labelled nucleotides 有权
公开(公告)号：US20060188901A1
公开(公告)日：2006-08-24
申请号：US11301578
申请日：2005-12-13
申请人： Colin Barnes , Shankar Balasubramanian , Xiaohai Liu , Harold Swerdlow , John Milton
发明人： Colin Barnes , Shankar Balasubramanian , Xiaohai Liu , Harold Swerdlow , John Milton
IPC分类号： C12Q1/68 , C12P19/34 , C07H21/04
CPC分类号： C07H19/06 , C07H19/10 , C07H19/16 , C07H19/20 , C07H21/00 , C12Q1/6869 , C12Q2525/186 , C12Q2535/113 , C12Q2525/197
摘要： Nucleosides and nucleotides are disclosed that are linked to detectable labels via a cleavable linker group.

8. 发明申请

US20060166864A1 Methods for modulating telomerase activity 审中-公开
标题翻译：调节端粒酶活性的方法
公开(公告)号：US20060166864A1
公开(公告)日：2006-07-27
申请号：US11398130
申请日：2006-04-04
申请人： Yen Choo , Mark Isalan , Sachin Patel , Shankar Balasubramanian , Xiohai Liu
发明人： Yen Choo , Mark Isalan , Sachin Patel , Shankar Balasubramanian , Xiohai Liu
IPC分类号： A61K38/16 , A61K48/00 , C12N15/87
CPC分类号： A61K38/1709 , C07K14/4702 , C07K2319/00
摘要： Disclosed herein are engineered zinc finger proteins which bind to telomeric structures; methods for their design, synthesis and use; and cells comprising a telomere-binding zinc finger protein. Methods for modulating telomerase activity using telomere-binding zinc finger proteins are also provided.
摘要翻译：本文公开了结合端粒结构的工程化锌指蛋白; 其设计，综合和使用方法; 和包含端粒结合锌指蛋白的细胞。还提供了使用端粒结合锌指蛋白调节端粒酶活性的方法。

9. 发明申请

US20060005233A1 Network security and applications to the fabric environment 有权
公开(公告)号：US20060005233A1
公开(公告)日：2006-01-05
申请号：US11198834
申请日：2005-08-05
申请人： James Kleinsteiber , Richard Hammons , Hung Nguyen , Shankar Balasubramanian , Vidya Renganararayanan
发明人： James Kleinsteiber , Richard Hammons , Hung Nguyen , Shankar Balasubramanian , Vidya Renganararayanan
IPC分类号： G06F15/16 , G06F17/30 , G06F7/04 , G06F7/58 , G06K19/00 , G06K9/00 , H04L9/32
CPC分类号： H04L63/08 , H04L63/0428 , H04L63/0823 , H04L63/0869 , H04L63/104 , H04L63/20 , H04L2463/102
摘要： A method and apparatus for securing networks, focusing on application in Fibre Channel networks. A combination of unique security techniques are combined to provide overall network security. Responsibility for security in the network is assigned to one or more designated entities. The designated entities deploy management information throughout the network to enhance security by modifying the capabilities and operational permissions of the devices participating in the network. For example, through network control: logical management access or physical I/O access may be limited on a per device or per I/O basis; and all devices and ports in the network operate only with other approved devices and ports. These designated entities can better manage network security by exploiting a unique link authentication system as well as a unique push-model secure distributed time service. The link authentication involves a multi-phase nonce exchange exploiting various derivations of the nonce and other information such as hashes and encryptions. The push-model secure time distribution departs from the traditional Fibre Channel pull mode time distribution and provides for secure and reliable distributed time so that various security attacks may be defeated.

10. 发明申请

US20130189743A1 LABELLED NUCLEOTIDES 有权
标题翻译：标签核心
公开(公告)号：US20130189743A1
公开(公告)日：2013-07-25
申请号：US13791597
申请日：2013-03-08
申请人： Shankar BALASUBRAMANIAN , Colin Barnes , Xiaohai Liu , John Milton
发明人： Shankar BALASUBRAMANIAN , Colin Barnes , Xiaohai Liu , John Milton
IPC分类号： C12P19/34
CPC分类号： C12Q1/6869 , C07H19/10 , C07H19/20 , C07H21/00 , C12P19/34 , C12Q1/6806 , C12Q1/6818 , C12Q1/6823 , C12Q1/6834 , C12Q1/6874 , C12Q1/6876 , C12Q2525/186
摘要： Nucleosides and nucleotides are disclosed that are linked to detectable labels via a cleavable linker group.
摘要翻译：公开了通过可切割连接基团与可检测标记物连接的核苷和核苷酸。

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