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1. 发明申请

US20100304423A1 CELL MEASURING VESSEL, EXTRACELLULAR POTENTIAL MEASURING METHOD, AND CHEMICAL TESTING METHOD 失效
标题翻译：细胞测量容器，细胞电位测量方法和化学测试方法
公开(公告)号：US20100304423A1
公开(公告)日：2010-12-02
申请号：US12733729
申请日：2008-09-17
申请人： Yasuyuki Asai , Nagakura Makoto , Fukami Takeaki , Oosumi Keisuke
发明人： Yasuyuki Asai , Nagakura Makoto , Fukami Takeaki , Oosumi Keisuke
IPC分类号： C12Q1/02 , C12M1/34
CPC分类号： B01L3/5085 , B01L2300/0645 , B01L2300/0829 , C12M41/36 , G01N33/4836 , G01N33/48728
摘要： The cell observation using a conventional well plate takes much costs. Each well 3 being opened at a top plate 2a of the well plate 1 has a diameter reduced portion 32 which inner circumferential surface 32a is conically hollowed. At a lower portion of the diameter reduced portion 32 is formed an inserting hole 33. In a detecting portion 4, an outer circumferential surface of a round-bar reference electrode 41 is covered by an insulating portion 42. The detecting portion 4 has an upper end portion 4a and a lower end portion 4b which outer circumferential surface is exposed to an outside without being covered by an insulating portion 42. On an upper side above the lower end portion 4b is formed a diameter expanded portion 4c in which an outer circumferential surface of the insulating portion 42 is covered with a measuring electrode 43. The detecting portion 4 is fixed to a well 3 whose diameter expanded portion 4c is inserted into an inserting hole 33 and its upper end portion 4a is contained in the well 3. In the detecting portion 4, the upper end surface 43a of the measuring electrode 43 is communicated with an inner circumferential surface 32a of the diameter reduced portion 32 positioned in an edge surrounding portion of the inserting hole 33.
摘要翻译：使用常规孔板的细胞观察需要很多成本。在井板1的顶板2a上开口的各孔3具有直径减小部32，该内周面32a是锥形中空的。在直径减小部32的下部形成有插入孔33.在检测部4中，圆棒状基准电极41的外周面被绝缘部42覆盖。检测部4具有上部端部4a和下端部4b，该外周面暴露于外部而不被绝缘部42覆盖。在下端部4b上方的上侧形成有直径扩大部4c，其中外周面绝缘部分42被测量电极43覆盖。检测部分4固定到孔3，孔3的直径扩大部分4c插入插入孔33中，并且其上端部分4a包含在井3中。在检测部分4，测量电极43的上端表面43a与位于边缘周边的直径减小部分32的内周表面32a相连通 g部分插入孔33。

2. 发明授权

US07732082B2 Fuel cell module 有权
标题翻译：燃料电池模块
公开(公告)号：US07732082B2
公开(公告)日：2010-06-08
申请号：US11578262
申请日：2005-04-26
申请人： Tomokazu Hayashi , Iwao Myojin , Tsutomu Ochi , Chisato Kato , Koichiro Kawakami , Hiroo Yoshikawa , Manabu Takahashi , Yasuyuki Asai
发明人： Tomokazu Hayashi , Iwao Myojin , Tsutomu Ochi , Chisato Kato , Koichiro Kawakami , Hiroo Yoshikawa , Manabu Takahashi , Yasuyuki Asai
IPC分类号： H01M2/08
CPC分类号： H01M8/241 , H01M8/0247 , H01M8/0263 , H01M8/0271 , H01M8/2457 , H01M8/2483
摘要： A fuel cell module, wherein slopes of a same angle θ relative to a bottom face are formed on both side faces to form a recessed groove in a tapered shape. Since the angle θ is provided to the side faces of the recessed groove, the exhaustion of gases from the accumulation of gasses to the outside can be assisted by the side faces with the angle θ more than in a case where the side faces of the recessed groove are formed in right angled shapes even if the accumulation of gases is produced between an adhesive agent and the inner surfaces of the recessed groove when first and second separators are joined to each other for modularization by covering the first separator on the second separator. Thus, the accumulation of the gases can be prevented from occurring.
摘要翻译：一种燃料电池模块，其中具有相同角度和斜角的斜面; 相对于底面形成在两个侧面上以形成呈锥形的凹槽。自从角度和角度设置在凹槽的侧面，气体从气体积聚到外部的排气可以通过具有角度和角度的侧面来辅助; 即使在凹槽的侧面形成为直角形状的情况下，即使当第一和第二隔板彼此接合时，在粘合剂和凹槽的内表面之间产生气体的积聚，通过覆盖第二分离器上的第一分离器来进行模块化。因此，可以防止气体的积聚。

3. 发明申请

US20080266622A1 SHEET PROCESSING APPARATUS 有权
标题翻译：板材加工设备
公开(公告)号：US20080266622A1
公开(公告)日：2008-10-30
申请号：US12107703
申请日：2008-04-22
申请人： Kenji Kawazoe , Haruo Uchida , Nozomu Nishiberi , Yoshiaki Watanabe , Yasuyuki Asai , Mitsuru Kondo
发明人： Kenji Kawazoe , Haruo Uchida , Nozomu Nishiberi , Yoshiaki Watanabe , Yasuyuki Asai , Mitsuru Kondo
IPC分类号： H04N1/04
CPC分类号： H04N1/00567 , H04N1/00578 , H04N1/00588 , H04N1/00591 , H04N1/00596 , H04N1/00602 , H04N1/0061 , H04N1/00612 , H04N1/00615 , H04N1/00623 , H04N1/00631 , Y10S271/902
摘要： A sheet processing apparatus includes a feeding portion that feeds an original or a recording medium, a reading portion that reads an original, and a recording portion that performs recording on a recording medium. The original or recording medium fed from the feeding portion can be selectively conveyed to the reading portion or the recording portion, thereby allowing for compactness of the apparatus as well as cost reduction.
摘要翻译：片材处理设备包括馈送原稿或记录介质的馈送部分，读取原稿的读取部分和在记录介质上执行记录的记录部分。从供给部供给的原稿或记录介质能够选择性地传送到读取部或记录部，从而允许装置的紧凑性以及成本降低。

4. 发明授权

US09856210B2 Pharmaceutical composition for prevention and treatment of amyotrophic lateral sclerosis 有权
公开(公告)号：US09856210B2
公开(公告)日：2018-01-02
申请号：US13820420
申请日：2011-09-02
申请人： Haruhisa Inoue , Shiho Kitaoka , Kayoko Tsukita , Ryosuke Takahashi , Gaku Murakami , Norio Nakatsuji , Motonari Uesugi , Yasuyuki Asai , Ayako Asai , Yuji Amagai , Kazuhiro Aiba
发明人： Haruhisa Inoue , Shiho Kitaoka , Kayoko Tsukita , Ryosuke Takahashi , Gaku Murakami , Norio Nakatsuji , Motonari Uesugi , Yasuyuki Asai , Yuji Amagai , Kazuhiro Aiba
IPC分类号： A61K31/17 , A61K31/44 , A61K45/06 , C07C275/30
CPC分类号： C07C275/30 , A61K31/17 , A61K31/44 , A61K45/06 , A61K2300/00
摘要： The present invention provides a prophylactic or therapeutic agent for amyotrophic lateral sclerosis, containing a 1,3-diphenylurea derivative or multikinase inhibitor.

5. 发明授权

US09527828B2 Method for expanding hematopoietic stem cells using heterocyclic compound 有权
标题翻译：使用杂环化合物扩增造血干细胞的方法
公开(公告)号：US09527828B2
公开(公告)日：2016-12-27
申请号：US12746666
申请日：2008-12-06
申请人： Taito Nishino , Norihisa Ishiwata , Katsuaki Miyaji , Shunsuke Iwamoto , Yasuyuki Asai , Makiko Yui
发明人： Taito Nishino , Norihisa Ishiwata , Katsuaki Miyaji , Shunsuke Iwamoto , Yasuyuki Asai , Makiko Yui
IPC分类号： C12N5/00 , C07D333/38 , C07D409/14 , C07D413/14 , C07D417/14 , C12N5/0789 , A61K35/00
CPC分类号： C07D333/38 , A61K35/00 , C07D409/14 , C07D413/14 , C07D417/14 , C12N5/0647 , C12N2501/999
摘要： An expansion agent for hematopoietic stem cells and/or hematopoietic progenitor cells useful for improvement in the efficiency of gene transfer into hematopoietic stem cells for gene therapy useful for treatment of various hematopoietic disorders is provided.A method for expanding hematopoietic stem cells and/or hematopoietic progenitor cells, which comprises culturing hematopoietic stem cells and/or hematopoietic progenitor cells ex vivo in the presence of a compound represented by the formula (I) (wherein X, Y, X, Ar1, R1, R2, R3, R4, R5, R6 and R7 are defined in the description), a tautomer or pharmaceutically acceptable salt of the compound or a solvate thereof.
摘要翻译：提供了用于造血干细胞和/或造血祖细胞的扩增剂，其用于提高用于治疗各种造血障碍的用于基因治疗的造血干细胞的基因转移效率。一种用于扩增造血干细胞和/或造血祖细胞的方法，其包括在式（I）表示的化合物（其中X，Y，X，Ar）存在下离体培养造血干细胞和/或造血祖细胞 1，R 1，R 2，R 3，R 4，R 5，R 6和R 7在说明书中定义），化合物的互变异构体或药学上可接受的盐或其溶剂合物。

6. 发明授权

US09212348B2 Method for producing hematopoietic stem cells using pyrazole compounds 有权
标题翻译：使用吡唑化合物制造造血干细胞的方法
公开(公告)号：US09212348B2
公开(公告)日：2015-12-15
申请号：US13990959
申请日：2011-12-01
申请人： Taito Nishino , Makiko Yui , Yasuyuki Asai , Ayako Asai
发明人： Taito Nishino , Makiko Yui , Yasuyuki Asai
IPC分类号： C12N15/00 , C12N5/0789 , C07D231/22 , A61K35/28
CPC分类号： C12N5/0647 , A61K35/28 , C07D231/22 , C12N2501/125 , C12N2501/145 , C12N2501/26 , C12N2501/999
摘要： An expanding agent for hematopoietic stem cells and/or hematopoietic progenitor cells useful as a therapy for various hematopoietic diseases and useful for improvement in the efficiency of gene transfer into hematopoietic stem cells for gene therapy is provided.A method of producing hematopoietic stem cells and/or hematopoietic progenitor cells, which comprises expanding hematopoietic stem cells by culturing hematopoietic stem cells ex vivo in the presence of a compound represented by the formula following (I), a tautomer or pharmaceutically acceptable salt of the compound or a solvate thereof (wherein R1 to R8 are as defined in the description).
摘要翻译：提供了用作造血干细胞和/或造血祖细胞的扩增剂，其用作各种造血疾病的治疗，并且可用于提高基因转移到造血干细胞中用于基因治疗的效率。一种产生造血干细胞和/或造血祖细胞的方法，其包括通过在下列通式（I）表示的化合物存在下体外培养造血干细胞来扩大造血干细胞，其中所述化合物的互变异构体或药学上可接受的盐化合物或其溶剂化物（其中R1至R8如说明书中所定义）。

7. 发明授权

US09099693B2 Fuel cell and fuel cell separator 有权
标题翻译：燃料电池和燃料电池分离器
公开(公告)号：US09099693B2
公开(公告)日：2015-08-04
申请号：US11886292
申请日：2006-03-23
申请人： Hiroya Nakaji , Tsutomu Ochi , Chisato Kato , Tsunemasa Nishida , Manabu Takahashi , Yasuyuki Asai
发明人： Hiroya Nakaji , Tsutomu Ochi , Chisato Kato , Tsunemasa Nishida , Manabu Takahashi , Yasuyuki Asai
IPC分类号： H01M8/04 , H01M8/02 , H01M8/10
CPC分类号： H01M8/2483 , H01M8/0228 , H01M8/0258 , H01M8/0267 , H01M8/0271 , H01M8/0276 , H01M2008/1095 , Y02E60/50
摘要： In a fuel cell having a separator in which main cooling water channels are formed, a separator for another unit cell stacked on the cooling water channel formation surface side of the separator, and a second sealing member interposed between the separators and to seal a cooling medium flowing in the main cooling water channels, an outer peripheral rib for regulating the flow of cooling water to the second sealing member side is provided inside relative to the second sealing member in the separator surface direction in order to improve the efficiency of cooling with the cooling medium.
摘要翻译：在具有形成有主冷却水通道的隔板的燃料电池中，叠层在隔板的冷却水通道形成面侧的另一单元电池用隔板，以及插入在隔板之间并密封冷却介质的第二密封构件在主冷却水通道中流动，在隔板表面方向上相对于第二密封构件设置有用于调节冷却水流向第二密封构件侧的外周肋，以提高冷却效率中。

8. 发明授权

US08636278B2 Feeding device and image forming apparatus having the same 有权
标题翻译：送料装置及其成像装置
公开(公告)号：US08636278B2
公开(公告)日：2014-01-28
申请号：US12946218
申请日：2010-11-15
申请人： Yuki Emoto , Yasuyuki Asai
发明人： Yuki Emoto , Yasuyuki Asai
IPC分类号： B65H3/52
CPC分类号： B65H3/0684 , B65H3/56 , B65H2402/543 , B65H2405/1136 , B65H2511/212 , B65H2515/30 , B65H2220/02 , B65H2220/08 , B65H2220/11 , B65H2220/01
摘要： The feeding device includes a storage unit, a feeding roller which rotates while contacting the uppermost sheet stored in the storage unit to move the uppermost sheet forward, a separation plate disposed forward in the movement direction of the uppermost sheet and provided with an inclined surface inclined with respect to the movement direction, and a separation auxiliary member is disposed along the inclined surface of the separation plate and operated by a force received when the uppermost sheet comes in contact. The separation auxiliary member includes a rotation shaft parallel with the inclined surface, and a first resistance part rotating about the rotation shaft as the center from an initial position projecting from the inclined surface to an embedded position embedded in the inclined surface as a friction coefficient of the first resistance part is higher than that of the inclined surface and the received force is increased.
摘要翻译：所述进给装置包括存储单元，所述进给辊在与所述存储单元中存储的最上面的纸张接触的同时旋转，以将最上面的纸张向前移动;分隔板，其在最上面的纸张的移动方向上向前设置，并且分离辅助构件沿着分离板的倾斜表面设置并且通过当最上面的片材接触时接收的力而操作。分离辅助构件包括与倾斜表面平行的旋转轴，以及第一电阻部分，其以从倾斜表面突出到初始位置的旋转轴为中心旋转到嵌入在倾斜表面中的嵌入位置，摩擦系数为第一电阻部分高于倾斜表面，并且接收力增加。

9. 发明授权

US07641186B2 Sheet feeding/conveying method and sheet feeding/conveying apparatus 失效
标题翻译：送纸/送纸方式和送纸/送纸装置
公开(公告)号：US07641186B2
公开(公告)日：2010-01-05
申请号：US11165166
申请日：2005-06-24
申请人： Yasuyuki Asai , Noboru Shimoyama
发明人： Yasuyuki Asai , Noboru Shimoyama
IPC分类号： B65H3/06
CPC分类号： B65H9/006 , B41J13/103 , B65H3/06 , B65H3/5261 , B65H2301/331 , B65H2301/512125 , B65H2404/7231
摘要： A sheet material feeding apparatus has a rotatable pressure plate for stacking sheet materials, a pickup roller for feeding the sheet material stacked on the pressure plate, a feed roller for feeding the sheet materials fed by the pickup roller and a separation roller contactable with the feed roller. A registration roller corrects oblique feeding of the sheet material by being abutted against the separated sheet material by the feeding roller and the separation roller, and after the registration roller rotates in synchronism with the pickup roller and the feed roller to start feeding the sheet material, pressure of the pressure plate against the pickup roller is released, and thereafter the feed roller and the separation roller are spaced apart from one another.
摘要翻译：片材供给装置具有用于堆叠片材的可旋转压板，用于供给堆叠在压板上的片材的拾取辊，用于馈送由拾取辊馈送的片材的进给辊和可与进给器接触的分离辊滚筒。定位辊通过由进给辊和分离辊抵靠分离的片材来校正片材的倾斜进给，并且在定位辊与拾取辊和进给辊同步旋转以开始进给片材之后，压力板抵靠拾取辊的压力被释放，之后进给辊和分离辊彼此间隔开。

10. 发明申请

US20080265481A1 RECORDING APPARATUS 有权
标题翻译：录音设备
公开(公告)号：US20080265481A1
公开(公告)日：2008-10-30
申请号：US12107699
申请日：2008-04-22
申请人： Haruo Uchida , Kenji Kawazoe , Nozomu Nishiberi , Koichiro Kawaguchi , Yoshiaki Watanabe , Yasuyuki Asai , Mitsuru Kondo
发明人： Haruo Uchida , Kenji Kawazoe , Nozomu Nishiberi , Koichiro Kawaguchi , Yoshiaki Watanabe , Yasuyuki Asai , Mitsuru Kondo
IPC分类号： B41F13/64
CPC分类号： B65H3/0607 , B65H3/44 , B65H9/106 , B65H2301/23 , B65H2801/06
摘要： A recording apparatus includes moving rollers and a feeding roller. The moving rollers move a set first sheet in a direction intersecting a conveying direction. The feeding roller conveys sheets at a sheet stacking portion. After the first sheet is shifted to a parallel position by the moving roller, a second sheet at a setting position and the first sheet at the parallel position are conveyed by the feeding roller.
摘要翻译：记录装置包括移动辊和进给辊。移动辊在与输送方向相交的方向上移动设定的第一片。送纸辊在片材堆叠部分输送纸张。在通过移动辊将第一片材移动到平行位置之后，在设置位置处的第二片材和平行位置处的第一片材通过进给辊传送。

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