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1. 发明申请

US20090064081A1 Process for Managing Complex Pre-Wired Net Segments in a VLSI Design 有权
标题翻译：在VLSI设计中管理复杂的预先有线网段的过程
公开(公告)号：US20090064081A1
公开(公告)日：2009-03-05
申请号：US11846577
申请日：2007-08-29
申请人： Christopher J. Berry , Michael A. Bowen , Michael R. Scheuermann , Michael H. Wood
发明人： Christopher J. Berry , Michael A. Bowen , Michael R. Scheuermann , Michael H. Wood
IPC分类号： G06F17/50
CPC分类号： G06F17/5077
摘要： A method for pre-wiring through multiple levels of metal using flues includes steps of: receiving information comprising flue geometries and flue properties; producing multiple routing patterns of a design for the flues; identifying macro instance terminals to be pre-wired in the design; selecting at least one of the routing patterns for the macro instance terminals in the design to avoid blockage; and instantiating the design such that the flues can be manipulated as vias.
摘要翻译：使用烟道预先接线多层金属的方法包括以下步骤：接收包括烟道几何形状和烟道特性的信息; 生成针对流感的设计的多个路由模式; 识别要在设计中预先布线的宏实例终端; 在设计中选择用于宏实例终端的路由模式中的至少一个以避免阻塞; 并实例化设计，使得烟道可以被操纵为过孔。

2. 发明授权

US07681169B2 Process for managing complex pre-wired net segments in a VLSI design 有权
标题翻译：在VLSI设计中管理复杂的预先有线网段的过程
公开(公告)号：US07681169B2
公开(公告)日：2010-03-16
申请号：US11846577
申请日：2007-08-29
申请人： Christopher J. Berry , Michael A. Bowen , Michael R. Scheuermann , Michael H. Wood
发明人： Christopher J. Berry , Michael A. Bowen , Michael R. Scheuermann , Michael H. Wood
IPC分类号： G06F17/50
CPC分类号： G06F17/5077
摘要： A method for pre-wiring through multiple levels of metal using flues includes steps of: receiving information comprising flue geometries and flue properties; producing multiple routing patterns of a design for the flues; identifying macro instance terminals to be pre-wired in the design; selecting at least one of the routing patterns for the macro instance terminals in the design to avoid blockage; and instantiating the design such that the flues can be manipulated as vias.
摘要翻译：使用烟道预先接线多层金属的方法包括以下步骤：接收包括烟道几何形状和烟道特性的信息; 生成针对流感的设计的多个路由模式; 识别要在设计中预先布线的宏实例终端; 在设计中选择用于宏实例终端的路由模式中的至少一个以避免阻塞; 并实例化设计，使得烟道可以被操纵为过孔。

3. 发明授权

US07980089B2 Refrigerator with a water and ice dispenser having an improved ice chute air seal 有权
标题翻译：具有冰和冰机的冰箱具有改进的冰槽空气密封
公开(公告)号：US07980089B2
公开(公告)日：2011-07-19
申请号：US11421831
申请日：2006-06-02
申请人： Michael A. Bowen , Lawrence J. Ertz , Bruce A. Kopf , Dean A. Martin , Scott W. Leimkuehler , Chad J. Rotter
发明人： Michael A. Bowen , Lawrence J. Ertz , Bruce A. Kopf , Dean A. Martin , Scott W. Leimkuehler , Chad J. Rotter
IPC分类号： F25C5/18
CPC分类号： F25C5/005 , F25C5/18 , F25C5/20 , F25C5/22 , F25D23/028 , F25D23/126 , F25D27/00 , F25D31/002 , F25D2323/021 , F25D2327/001 , F25D2500/02
摘要： A refrigerator having an ice and water dispenser has a seal to sealingly engage the ice compartment when the refrigerator door is closed. The seal is flexible to accommodate manufacturing tolerance. The seal may be impregnated with a friction reducing agent to increase life of the seal.
摘要翻译：具有冰和水分配器的冰箱具有密封，以在冰箱门关闭时密封地接合冰室。密封是灵活的，以适应制造公差。密封件可以用减摩剂浸渍以增加密封件的使用寿命。

4. 发明授权

US5968768A CD6 ligand encoding sequence 失效
标题翻译： CD6配体编码序列
公开(公告)号：US5968768A
公开(公告)日：1999-10-19
申请号：US432016
申请日：1995-05-01
申请人： Barton F. Haynes , Alejandro Aruffo , Dhavalkumar Patel , Michael A. Bowen , Hans Marquardt
发明人： Barton F. Haynes , Alejandro Aruffo , Dhavalkumar Patel , Michael A. Bowen , Hans Marquardt
IPC分类号： G01N33/53 , A61K38/00 , A61P37/06 , C07K14/705 , C07K14/725 , C07K16/28 , C12N5/10 , C12N15/09 , C12N15/12 , C12P21/00 , C12R1/91
CPC分类号： C07K14/70503 , C07K16/2803 , A61K38/00 , C07K2319/30
摘要： The present invention relates to an isolated nucleic acid molecule having a sequence that encodes a CD6 ligand present on the surface of thymic epithelial cells, monocytes, activated T cells and a variety of other cell types. The invention further relates to a construct containing the nucleic acid molecule and to a host cell comprising same. Further, the invention relates to a method of producing a CD6 ligand.
摘要翻译：本发明涉及具有编码存在于胸腺上皮细胞，单核细胞，活化的T细胞和多种其他细胞类型的表面上的CD6配体的序列的分离的核酸分子。本发明还涉及包含核酸分子的构建体和包含该核酸分子的宿主细胞。此外，本发明涉及一种制备CD6配体的方法。

5. 发明授权

US07037676B2 Drosophila tumor necrosis factor class molecule polynucleotides and variants thereof 有权
标题翻译：果蝇肿瘤坏死因子类分子（“DmTNFv2”）多核苷酸及其变体
公开(公告)号：US07037676B2
公开(公告)日：2006-05-02
申请号：US09813329
申请日：2001-03-20
申请人： Pamela M. Carroll , Jian Chen , Chandra S. Ramanathan , Hong Xiao , Michael A. Bowen
发明人： Pamela M. Carroll , Jian Chen , Chandra S. Ramanathan , Hong Xiao , Michael A. Bowen
IPC分类号： C12P21/06 , C12N15/09 , C12N15/19 , C07H21/04
CPC分类号： C07K14/525 , A01K2217/05
摘要： The present invention provides novel polynucleotides encoding Drosophila DmTNF polypeptides, fragments and homologs thereof. The present invention also is directed to novel polynucleotides encoding two Drosophila DmTNF variants, DmTNFv1 and DmTNFv2 polypeptides, fragments and homologs thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention, in addition to methods of genetically modifying Drosophila or cultured cells to express or mis-express DmTNF, DmTNFv1, or DmTNFv2. The invention also relates to the use of such modified insects or cells to characterize DmTNF activity, identify TNF-like genes and/or genes implicated in modulating TNF, characterize TNF signaling pathways, and/or to identify modulators of DmTNF activity.
摘要翻译：本发明提供了编码果蝇DmTNF多肽的新型多核苷酸，其片段和同系物。本发明还涉及编码两种果蝇DmTNF变体，DmTNFv1和DmTNFv2多肽的新型多核苷酸，其片段和同系物。还提供了载体，宿主细胞，抗体以及用于产生所述多肽的重组和合成方法。除了遗传修饰果蝇或培养细胞以表达或错误表达DmTNF，DmTNFv1或DmTNFv2的方法之外，本发明还涉及用于鉴定本发明的多核苷酸和多肽的激动剂和拮抗剂的筛选方法。本发明还涉及这种修饰的昆虫或细胞用于表征DmTNF活性，鉴定涉及调节TNF，表征TNF信号传导途径和/或鉴定DmTNF活性调节剂的TNF-样基因和/或基因的用途。

6. 发明授权

US06772606B2 Method and apparatus for a plastic evaporator fan shroud assembly 有权
标题翻译：塑料蒸发器风扇护罩组件的方法和装置
公开(公告)号：US06772606B2
公开(公告)日：2004-08-10
申请号：US10195174
申请日：2002-07-15
申请人： Bruce A. Kopf , Tim L. Coulter , Richard A. Kirchner , Michael A. Bowen , Troy M. Anderson , Eric K. Silbaugh
发明人： Bruce A. Kopf , Tim L. Coulter , Richard A. Kirchner , Michael A. Bowen , Troy M. Anderson , Eric K. Silbaugh
IPC分类号： F25D1706
CPC分类号： F25D17/067 , F04D29/646 , F25D2317/0681
摘要： An evaporator fan assembly includes a shroud have a plurality of irregularly staggered shroud legs radially outwardly spaced from a fan orifice and terminating in a motor mount. A motor is removably secured to the motor mount by a motor clip. The motor clip preferably includes a pair of legs terminating in a catch or hook that may be secured to a cross-member or support bar between the shroud legs. The motor is secured in a centered position to properly align a fan blade in the fan orifice. The fan blade is secured to the drive shaft of the motor which passes through a hole in the motor mount. A shroud cover may be secured to the shroud.
摘要翻译：蒸发器风扇组件包括护罩，其具有与风扇孔径向向外间隔开并终止于电动机安装件的多个不规则交错的护罩腿。电动机通过电动机夹可拆卸地固定到电动机支架上。马达夹优选地包括终止于卡扣或钩的一对腿，所述钩可以固定到护罩腿之间的横向构件或支撑杆上。电机固定在中心位置，以正确对准风扇孔中的风扇叶片。风扇叶片固定到电动机的驱动轴上，该驱动轴通过电动机支架的孔。护罩盖可以固定到护罩上。

7. 发明授权

US06546529B1 Method for performing coupling analysis 失效
标题翻译：执行耦合分析的方法
公开(公告)号：US06546529B1
公开(公告)日：2003-04-08
申请号：US09677362
申请日：2000-10-02
申请人： Allan H. Dansky , Michael A. Bowen , Peter J. Camporese , Alina Deutsch , Howard H. Smith
发明人： Allan H. Dansky , Michael A. Bowen , Peter J. Camporese , Alina Deutsch , Howard H. Smith
IPC分类号： G06F945
CPC分类号： G06F17/5036
摘要： Deterministic evaluation of coupling noise voltage is a function of many physical and electrical parameters such as wiring level, widths, spacing, net topologies, drv impedance and slew rates. This evaluation requires electrical modeling and subsequent circuit simulation to assess the sensitivities of these parameters. These sensitivities can be categorized as coupling guidelines that can be directly linked through extracted physical design data. This invention discloses the development and implementation of a technique for using a coupling guideline table early in the design of an integrated circuit when all the parameters generally required for coupling noise voltage calculations are not available. The steps include: creating a flat wire routing map of the integrated circuit, identifying the coupled wire segments on the integrated circuit, tracking wire interconnection patterns on the integrated circuit, deriving electrical parameters for the coupled wire segments, and generating a coupling guideline table with parameters for a plurality of electrical parameters. The parameters in the coupling guideline table are applied to the derived electrical parameters and a report is generated that lists the derived electrical parameters that fail to comply with the parameters in the coupling guideline table.
摘要翻译：耦合噪声电压的确定性评估是许多物理和电气参数的函数，如布线级别，宽度，间距，网络拓扑，drv阻抗和转换速率。该评估需要电气建模和后续电路仿真来评估这些参数的灵敏度。这些敏感性可以归类为可以通过提取的物理设计数据直接相关联的耦合准则。本发明公开了当耦合噪声电压计算通常需要的所有参数不可用时，在集成电路设计早期使用耦合指南表的技术的开发和实现。步骤包括：创建集成电路的扁平布线图，识别集成电路上的耦合线段，跟踪集成电路上的导线互连图案，导出耦合的线段的电参数，以及生成具有用于多个电参数的参数。耦合准则表中的参数应用于导出的电气参数，并生成报告，列出导出的电气参数不符合耦合指南表中的参数。

8. 发明授权

US5998172A Anti-CD6 ligand antibodies 失效
标题翻译：抗CD6配体抗体
公开(公告)号：US5998172A
公开(公告)日：1999-12-07
申请号：US684594
申请日：1996-07-18
申请人： Barton F. Haynes , Alejandro Aruffo , Dhavalkumar D. Patel , Michael A. Bowen , Hans Marquardt , Anthony W. Siadak
发明人： Barton F. Haynes , Alejandro Aruffo , Dhavalkumar D. Patel , Michael A. Bowen , Hans Marquardt , Anthony W. Siadak
IPC分类号： G01N33/53 , A61K31/00 , A61K38/00 , A61K39/395 , A61K45/00 , A61P37/00 , A61P37/02 , C07K14/47 , C07K14/705 , C07K16/28 , C12N5/00 , C12N5/10 , C12N15/02 , C12P21/08 , C12R1/91 , G01N33/566 , G01N33/577 , G01N33/68 , C12N5/12
CPC分类号： C07K14/705 , C07K14/70503 , C07K14/70596 , C07K16/2803 , C07K16/2896 , G01N33/68 , A61K38/00 , C07K2319/00 , C07K2319/30 , G01N2333/70503
摘要： The present invention relates, in general, to CD6 and, in particular, to a CD6 ligand present on the surface of thymic epithelial cells, monocytes, activated T cells and a variety of other cell types. The invention further relates to methods of inhibiting the interaction of CD6 and the CD6 ligand, and to methods of screening compounds for their ability to inhibit that interaction. The invention also relates to antibodies, and binding fragments thereof, specific for CD6 ligand.
摘要翻译：本发明一般涉及CD6，特别是涉及存在于胸腺上皮细胞，单核细胞，活化的T细胞和多种其他细胞类型的表面上的CD6配体。本发明还涉及抑制CD6和CD6配体相互作用的方法，以及筛选化合物抑制该相互作用的能力的方法。本发明还涉及对CD6配体特异性的抗体及其结合片段。

9. 发明授权

US08844311B2 Refrigerator with a water and ice dispenser having an improved ice chute air seal 有权
标题翻译：具有冰和冰机的冰箱具有改进的冰槽空气密封
公开(公告)号：US08844311B2
公开(公告)日：2014-09-30
申请号：US13185232
申请日：2011-07-18
申请人： Michael A. Bowen , Lawrence J. Ertz , Bruce A. Kopf , Dean A. Martin , Scott W. Leimkuehler , Chad J. Rotter
发明人： Michael A. Bowen , Lawrence J. Ertz , Bruce A. Kopf , Dean A. Martin , Scott W. Leimkuehler , Chad J. Rotter
IPC分类号： F25C5/18
CPC分类号： F25C5/005 , F25C5/18 , F25C5/20 , F25C5/22 , F25D23/028 , F25D23/126 , F25D27/00 , F25D31/002 , F25D2323/021 , F25D2327/001 , F25D2500/02
摘要： A refrigerator having an ice and water dispenser has a seal to sealingly engage the ice compartment when the refrigerator door is closed. The seal is flexible to accommodate manufacturing tolerance. The seal may be impregnated with a friction reducing agent to increase life of the seal.
摘要翻译：具有冰和水分配器的冰箱具有密封，以在冰箱门关闭时密封地接合冰室。密封是灵活的，以适应制造公差。密封件可以用减摩剂浸渍以增加密封件的寿命。

10. 发明授权

US07703297B2 Refrigerator with a water and ice dispenser having a motorized chute extension door 有权
标题翻译：冰箱带有一个带有电动滑槽延伸门的水和冰机
公开(公告)号：US07703297B2
公开(公告)日：2010-04-27
申请号：US11421827
申请日：2006-06-02
申请人： Michael A. Bowen , Lawrence J. Ertz , Bruce A. Kopf , Dean A. Martin , Scott W. Leimkuehler , Chad J. Rotter
发明人： Michael A. Bowen , Lawrence J. Ertz , Bruce A. Kopf , Dean A. Martin , Scott W. Leimkuehler , Chad J. Rotter
IPC分类号： F25C5/18
CPC分类号： F25C5/005 , F25C5/18 , F25C5/20 , F25C5/22 , F25D23/028 , F25D23/126 , F25D27/00 , F25D31/002 , F25D2323/021 , F25D2327/001 , F25D2500/02
摘要： A refrigerator having an ice and water dispenser. The dispenser includes an ice chute door actuated by an electric motor for reducing energy consumption over traditional solenoid activated doors.
摘要翻译：具有冰和水分配器的冰箱。分配器包括由电动机驱动的用于降低传统电磁致动门的能量消耗的冰门。

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