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    • 7. 发明授权
    • Radio frequency receiver
    • 射频接收机
    • US08774747B2
    • 2014-07-08
    • US13488902
    • 2012-06-05
    • Seok-bong HyunBong Hyuk ParkYun Ho ChoiJae Ho Jung
    • Seok-bong HyunBong Hyuk ParkYun Ho ChoiJae Ho Jung
    • H04B1/10H03D1/06
    • H03F3/45179H03F3/72H03F2200/294H03F2203/45302H03F2203/45394H03F2203/7236
    • A radio frequency receiver of the present invention removes out-of-band jamming signals and interference signals without SAW filters. The radio frequency receiver includes: a low noise amplifier amplifying a signal received through an antenna; a second order intermodulation cancellation unit removing second order intermodulation caused by an out-of-band jamming or interference signal included in the signal output from the low noise amplifier; a passive mixer unit converting a frequency of the signal output from the second order intermodulation cancellation unit; and a low pass filter unit removing an out-of-band jamming or interference signal included in the signal output from the passive mixer unit and delivering the signal with the out-of-band jamming or interference signal removed therefrom to a transimpedance amplifier.
    • 本发明的射频接收机在没有SAW滤波器的情况下去除带外干扰信号和干扰信号。 射频接收机包括:放大通过天线接收的信号的低噪声放大器; 二阶互调消除单元去除由低噪声放大器输出的信号中包含的带外干扰或干扰信号引起的二阶互调; 无源混频器单元,转换从二阶互调消除单元输出的信号的频率; 以及低通滤波器单元,去除从无源混频器单元输出的信号中包含的带外干扰或干扰信号,并且将从其去除的带外干扰或干扰信号的信号传送到跨阻抗放大器。
    • 8. 发明申请
    • RADIO FREQUENCY RECEIVER
    • 无线电频率接收机
    • US20130135048A1
    • 2013-05-30
    • US13488902
    • 2012-06-05
    • Seok-bong HYUNBong Hyuk ParkYun Ho ChoiJae Ho Jung
    • Seok-bong HYUNBong Hyuk ParkYun Ho ChoiJae Ho Jung
    • H03F3/45H03F3/16
    • H03F3/45179H03F3/72H03F2200/294H03F2203/45302H03F2203/45394H03F2203/7236
    • A radio frequency receiver of the present invention removes out-of-band jamming signals and interference signals without SAW filters. The radio frequency receiver includes: a low noise amplifier amplifying a signal received through an antenna; a second order intermodulation cancellation unit removing second order intermodulation caused by an out-of-band jamming or interference signal included in the signal output from the low noise amplifier; a passive mixer unit converting a frequency of the signal output from the second order intermodulation cancellation unit; and a low pass filter unit removing an out-of-band jamming or interference signal included in the signal output from the passive mixer unit and delivering the signal with the out-of-band jamming or interference signal removed therefrom to a transimpedance amplifier.
    • 本发明的射频接收机在没有SAW滤波器的情况下去除带外干扰信号和干扰信号。 射频接收机包括:放大通过天线接收的信号的低噪声放大器; 二阶互调消除单元去除由低噪声放大器输出的信号中包含的带外干扰或干扰信号引起的二阶互调; 无源混频器单元,转换从二阶互调消除单元输出的信号的频率; 以及低通滤波器单元,去除从无源混频器单元输出的信号中包含的带外干扰或干扰信号,并且将从其去除的带外干扰或干扰信号的信号传送到跨阻抗放大器。
    • 9. 发明申请
    • TRICARBONYL TECHNETIUM-99m OR RHENIUM-188 LABELED CYCLIC RGD DERIVATIVES, A PREPARATION METHOD THEREOF, AND A PHARMACEUTICAL COMPOSITION CONTAINING THE DERIVATIVES AS AN ACTIVE INGREDIENT FOR USE IN THE DIAGNOSIS OR TREATMENT OF ANGIOGENESIS-RELATED DISEASES
    • 三溴联苯技术-99m或RHENIUM-188标记循环RGD衍生物及其制备方法,以及含有衍生物作为活性成分的药物组合物用于诊断或治疗血管发生相关性疾病
    • US20130064766A1
    • 2013-03-14
    • US13699511
    • 2011-05-24
    • Byung Chul LeeSang Eun KimJi Sun KimByung Seok MoonJae Ho Jung
    • Byung Chul LeeSang Eun KimJi Sun KimByung Seok MoonJae Ho Jung
    • A61K51/08C07K1/13A61P9/00C07K7/64
    • A61K51/088A61K51/082C07D273/06C07D498/06C07D498/16C07K7/64G01N33/574G01N33/60
    • The present invention relates to tricarbonyl technetium-99m or rhenium-188 labeled cyclic RGD derivatives, a preparation method thereof, and a pharmaceutical composition containing the derivative as an active ingredient for use in the diagnosis or treatment (radiotherapy) of angiogenesis-related diseases. The tricarbonyl technetium-99m or rhenium-188 labeled cyclic RGD derivatives of the present invention has a high subnanomolar affinity to integrin αvβ3 (also called as a vitronectin receptor) that is activated in an angiogenic action induced by a tumor, reflects a high tumor image of the tricatvonyl technetium-99m labeled cyclic RGD derivative after initial intake in an animal in which cancer cells are transplanted, and acts exclusively upon cancer cells having selectively activated integrin αvβ3 because of a substantially low intake into the liver and intestines, compared to existing known radioactive isotope labeled cyclic RGD derivatives. These results show that the rhenium-188 labeled derivative, a therapeutic nuclide using the same precursor as used in the technetium-99m labeling, effectively inhibits the growth of a tumor and demonstrates therapeutic efficacy when administered via tail vein injection to an animal model bearing tumor, compared to a case where only saline has been injected, thereby making it useful as a medicine for the diagnosis or treatment of angiogenesis-related diseases.
    • 本发明涉及三羰基锝-99m或铼-188标记的环状RGD衍生物,其制备方法和含有该衍生物作为血管生成相关疾病的诊断或治疗(放射治疗)的有效成分的药物组合物。 本发明的三羰基锝-99m或铼-188标记的环状RGD衍生物在由肿瘤诱导的血管生成作用中被激活的整联蛋白αv&bgr 3(也称为玻连蛋白受体)具有高亚纳摩尔亲和力,反映了高 在移植了癌细胞的动物中,首先摄入三氯乙酰锝-99m标记的环状RGD衍生物的肿瘤图像,并且完全作用于具有选择性活化整联蛋白αv&bgr3的癌细胞,因为进入肝脏和肠的摄入量很低, 与现有已知的放射性同位素标记的环状RGD衍生物相比。 这些结果表明,使用与锝-99m标记中使用的相同前体的治疗性核素的铼-188标记的衍生物有效地抑制肿瘤的生长,并且当通过尾静脉注射施用于携带肿瘤的动物模型时显示出治疗功效 ,与仅注射盐水的情况相比,可以用作诊断或治疗血管发生相关疾病的药物。
    • 10. 发明授权
    • Front-end apparatus of wireless transceiver using RF passive elements
    • 使用RF无源元件的无线收发器的前端设备
    • US09136612B2
    • 2015-09-15
    • US13619960
    • 2012-09-14
    • Heon Kook KwonByung Su KangJae Ho Jung
    • Heon Kook KwonByung Su KangJae Ho Jung
    • H01Q21/28
    • H01Q21/28
    • Disclosed is a front-end apparatus of an RF transceiver connected with an antenna in a wireless communication system. The front-end apparatus of an RF transceiver using radio-frequency passive elements includes: a plurality of band pass filters configured a transmission signal and a reception signal; a first circulator configured to output a first transmission signal to a second terminal and output a second reception signal input; a second circulator configured to output a second transmission signal input into the first terminal to the second terminal and output a first reception signal input into the second terminal to the third terminal; a passive directional double pole and double throw switch configured to process a route to be changed depending on directions of an input and an output; a first antenna configured to transmit the first transmission signal; and a second antenna configured to transmit the second transmission.
    • 公开了一种在无线通信系统中与天线连接的RF收发器的前端装置。 使用射频无源元件的RF收发器的前端装置包括:配置有发送信号和接收信号的多个带通滤波器; 第一循环器,被配置为将第一发送信号输出到第二终端,并输出第二接收信号输入; 第二循环器,被配置为将输入到所述第一端子的第二传输信号输出到所述第二端子,并将输入到所述第二端子的第一接收信号输出到所述第三端子; 被动方向双极双掷开关,被配置为根据输入和输出的方向处理要改变的路线; 第一天线,被配置为发送所述第一发送信号; 以及被配置为发送所述第二传输的第二天线。