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    • 10. 发明申请
    • MASS SPECTROMETER
    • 质谱仪
    • US20100065733A1
    • 2010-03-18
    • US12306162
    • 2007-06-25
    • Robert Harold BatemanKevin GilesSteven Derek PringleJason Lee Wildgoose
    • Robert Harold BatemanKevin GilesSteven Derek PringleJason Lee Wildgoose
    • B01D59/44H01J49/00
    • H01J49/429G01N27/622H01J49/0031H01J49/004
    • A mass spectrometer is disclosed comprising an ion mobility spectrometer or separator (6) arranged upstream of a collision or fragmentation cell (8). Ions are separated according to their ion mobility within the ion mobility spectrometer or separator (6). The kinetic energy of the ions exiting the ion mobility spectrometer or separator (6) is increased substantially linearly with time in order to optimise the fragmentation energy of ions as they enter the collision or fragmentation cell (8). During the time that the potential of the ion mobility spectrometer or separator (6) is being varied, the potential of ion-optical components upstream of the ion mobility spectrometer or separator (6) such as an ion source (1), ion guide (2), quadrupole mass filter (3), optional second collision or fragmentation cell (4) and an ion trapping device (5) are kept constant.
    • 公开了一种质谱仪,其包括设置在碰撞或分裂单元(8)的上游的离子迁移谱仪或分离器(6)。 根据离子迁移谱仪或分离器(6)内的离子迁移率分离离子。 离子离子迁移谱仪或分离器(6)离子的动能随着时间的推移基本线性地增加,以优化离子进入碰撞或破碎电池(8)时的碎裂能。 在离子迁移谱仪或分离器(6)的电位变化的时间内,离子迁移谱仪或分离器(6)上游离子光学部件的离子源(1),离子导向器 2),四极质量过滤器(3),任选的第二碰撞或碎裂单元(4)和离子捕获装置(5)保持恒定。