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1. 发明授权

US08452402B2 Optical sensing device for use in a medical device 有权
标题翻译：用于医疗设备的光学感测装置
公开(公告)号：US08452402B2
公开(公告)日：2013-05-28
申请号：US12107921
申请日：2008-04-23
申请人： Robert M. Ecker , Jonathan L. Kuhn , James D. Reinke , Can Cinbis , Timothy J. Davis , Paul F. Gerrish , Jonathan P. Roberts
发明人： Robert M. Ecker , Jonathan L. Kuhn , James D. Reinke , Can Cinbis , Timothy J. Davis , Paul F. Gerrish , Jonathan P. Roberts
IPC分类号： A61B5/1455
CPC分类号： A61B5/0086 , A61B2562/028 , A61N1/3621 , A61N1/36557 , A61N1/375 , A61N1/3956
摘要： A reflectance-type optical sensor includes one or more photodiodes formed in a semiconductor substrate. A well having sidewalls and a bottom is formed in the top surface of the substrate, and a reflective layer is formed on the sidewalls and bottom. A light-emitting diode (LED) is mounted in the well, so that light emitted laterally and rearwardly from the LED strikes the sidewalls or bottom and is redirected in a direction generally perpendicular to the top surface of the substrate. The optical sensor can be fabricated using microelectromechanical systems (MEMS) fabrication techniques.
摘要翻译：反射型光学传感器包括在半导体衬底中形成的一个或多个光电二极管。在衬底的顶表面中形成具有侧壁和底部的阱，并且在侧壁和底部上形成反射层。发光二极管（LED）安装在井中，使得从LED侧向和向后发射的光撞击侧壁或底部，并且在大体上垂直于衬底的顶表面的方向上重定向。光学传感器可以使用微机电系统（MEMS）制造技术来制造。

2. 发明申请

US20090270953A1 Optical Device 有权
标题翻译：光学设备
公开(公告)号：US20090270953A1
公开(公告)日：2009-10-29
申请号：US12107921
申请日：2008-04-23
申请人： Robert M. Ecker , Jonathan L. Kuhn , James D. Reinke , Can Cinbis , Timothy J. Davis , Paul F. Gerrish , Jonathan P. Roberts
发明人： Robert M. Ecker , Jonathan L. Kuhn , James D. Reinke , Can Cinbis , Timothy J. Davis , Paul F. Gerrish , Jonathan P. Roberts
IPC分类号： A61N5/06 , H01L31/12
CPC分类号： A61B5/0086 , A61B2562/028 , A61N1/3621 , A61N1/36557 , A61N1/375 , A61N1/3956
摘要： A reflectance-type optical sensor includes one or more photodiodes formed in a semiconductor substrate. A well having sidewalls and a bottom is formed in the top surface of the substrate, and a reflective layer is formed on the sidewalls and bottom. A light-emitting diode (LED) is mounted in the well, so that light emitted laterally and rearwardly from the LED strikes the sidewalls or bottom and is redirected in a direction generally perpendicular to the top surface of the substrate. The optical sensor can be fabricated using microelectromechanical systems (MEMS) fabrication techniques.
摘要翻译：反射型光学传感器包括在半导体衬底中形成的一个或多个光电二极管。在衬底的顶表面中形成具有侧壁和底部的阱，并且在侧壁和底部上形成反射层。发光二极管（LED）安装在井中，使得从LED侧向和向后发射的光撞击侧壁或底部，并且在大体上垂直于衬底的顶表面的方向上重定向。光学传感器可以使用微机电系统（MEMS）制造技术来制造。

3. 发明授权

US08275435B2 Co-location of emitters and detectors and method of operation 有权
标题翻译：发射器和探测器的共同定位和操作方法
公开(公告)号：US08275435B2
公开(公告)日：2012-09-25
申请号：US12690957
申请日：2010-01-21
申请人： Jonathan L. Kuhn , Jonathan P. Roberts , Andrew J. Ries , James D. Reinke , Jeffrey M. Jelen , Robert M. Ecker , Timothy J. Davis , Can Cinbis , Thomas A. Anderson
发明人： Jonathan L. Kuhn , Jonathan P. Roberts , Andrew J. Ries , James D. Reinke , Jeffrey M. Jelen , Robert M. Ecker , Timothy J. Davis , Can Cinbis , Thomas A. Anderson
IPC分类号： A61B5/00
CPC分类号： A61B5/1459 , A61B5/14542 , A61B5/1495 , A61B2562/0233 , A61B2562/046 , A61N1/36557 , G06F19/00 , G16H40/63
摘要： An implantable medical device having an optical sensor selects the function of modular opto-electronic assemblies included in the optical sensor. Each assembly is provided with at least one light emitting device and at least one light detecting device. A device controller coupled to the optical sensor controls the function of each the assemblies. The controller executes a sensor performance test and selects at least one of the plurality of assemblies to operate as a light emitting assembly in response to a result of the performance test. The controller selects at least one other of the plurality of optical sensor assemblies to operate as a light detecting assembly in response to a result of the performance test.
摘要翻译：具有光学传感器的可植入医疗装置选择包括在光学传感器中的模块化光电组件的功能。每个组件设置有至少一个发光装置和至少一个光检测装置。耦合到光学传感器的设备控制器控制每个组件的功能。控制器执行传感器性能测试，并且响应于性能测试的结果，选择多个组件中的至少一个作为发光组件进行操作。响应于性能测试的结果，控制器选择多个光学传感器组件中的至少一个以作为光检测组件进行操作。

4. 发明申请

US20100185262A1 CO-LOCATION OF EMITTERS AND DETECTORS AND METHOD OF OPERATION 有权
标题翻译：发射器和探测器的合作位置及其操作方法
公开(公告)号：US20100185262A1
公开(公告)日：2010-07-22
申请号：US12690957
申请日：2010-01-21
申请人： Jonathan L. Kuhn , Jonathan P. Roberts , Andrew J. Ries , James D. Reinke , Jeffrey M. Jelen , Robert M. Ecker , Timothy J. Davis , Can Cinbis , Thomas A. Anderson
发明人： Jonathan L. Kuhn , Jonathan P. Roberts , Andrew J. Ries , James D. Reinke , Jeffrey M. Jelen , Robert M. Ecker , Timothy J. Davis , Can Cinbis , Thomas A. Anderson
IPC分类号： A61N1/08 , A61B5/00
CPC分类号： A61B5/1459 , A61B5/14542 , A61B5/1495 , A61B2562/0233 , A61B2562/046 , A61N1/36557 , G06F19/00 , G16H40/63
摘要： An implantable medical device having an optical sensor selects the function of modular opto-electronic assemblies included in the optical sensor. Each assembly is provided with at least one light emitting device and at least one light detecting device. A device controller coupled to the optical sensor controls the function of each the assemblies. The controller executes a sensor performance test and selects at least one of the plurality of assemblies to operate as a light emitting assembly in response to a result of the performance test. The controller selects at least one other of the plurality of optical sensor assemblies to operate as a light detecting assembly in response to a result of the performance test
摘要翻译：具有光学传感器的可植入医疗装置选择包括在光学传感器中的模块化光电组件的功能。每个组件设置有至少一个发光装置和至少一个光检测装置。耦合到光学传感器的设备控制器控制每个组件的功能。控制器执行传感器性能测试，并且响应于性能测试的结果，选择多个组件中的至少一个作为发光组件进行操作。响应于性能测试的结果，控制器选择多个光学传感器组件中的至少另一个作为光检测组件进行操作

5. 发明申请

US20090156912A1 IMPLANTABLE OPTICAL SENSOR AND METHOD FOR MANUFACTURE 有权
标题翻译：可植入的光学传感器及其制造方法
公开(公告)号：US20090156912A1
公开(公告)日：2009-06-18
申请号：US11955056
申请日：2007-12-12
申请人： Jonathan L. Kuhn , Timothy J. Davis , Can Cinbis , Robert M. Ecker , Shawn D. Knowles
发明人： Jonathan L. Kuhn , Timothy J. Davis , Can Cinbis , Robert M. Ecker , Shawn D. Knowles
IPC分类号： A61B5/1459 , H01L31/18
CPC分类号： A61B5/14542 , A61B5/0084 , A61B5/0086 , A61B5/14532 , A61B5/14552 , A61B5/1459 , A61B5/6846 , A61B2562/02 , A61B2562/043 , A61B2562/146
摘要： An implantable optical sensor and associated manufacturing method include a sensor housing having an inner surface and an outer surface and a window formed in the housing extending between the housing inner surface and the housing outer surface. An opto-electronic device enclosed within the housing and having a photonic surface is operatively positioned proximate the window for emitting light through the window or detecting light through the window. An optical coupling member is positioned between the opto-electronic device and the window for reducing light reflection at a surface within the implantable optical sensor.
摘要翻译：可植入光学传感器和相关联的制造方法包括具有内表面和外表面的传感器外壳和形成在壳体中的窗口，该壳体在壳体内表面和壳体外表面之间延伸。封闭在壳体内并且具有光子表面的光电器件可操作地定位在窗口附近，用于通过窗口发射光或通过窗口检测光。光耦合构件位于光电器件和窗口之间，用于减少可植入光学传感器内的表面处的光反射。

6. 发明授权

US08275432B2 Implantable optical sensor and method for manufacture 有权
标题翻译：植入式光学传感器及其制造方法
公开(公告)号：US08275432B2
公开(公告)日：2012-09-25
申请号：US11955056
申请日：2007-12-12
申请人： Jonathan L. Kuhn , Timothy J. Davis , Can Cinbis , Robert M. Ecker , Shawn D. Knowles , Thomas A. Anderson , Jeffrey M. Jelen
发明人： Jonathan L. Kuhn , Timothy J. Davis , Can Cinbis , Robert M. Ecker , Shawn D. Knowles , Thomas A. Anderson , Jeffrey M. Jelen
IPC分类号： A61B5/1455
CPC分类号： A61B5/14542 , A61B5/0084 , A61B5/0086 , A61B5/14532 , A61B5/14552 , A61B5/1459 , A61B5/6846 , A61B2562/02 , A61B2562/043 , A61B2562/146
摘要： An implantable optical sensor and associated manufacturing method include a sensor housing having an inner surface and an outer surface and a window formed in the housing extending between the housing inner surface and the housing outer surface. An opto-electronic device enclosed within the housing and having a photonic surface is operatively positioned proximate the window for emitting light through the window or detecting light through the window. An optical coupling member is positioned between the opto-electronic device and the window for reducing light reflection at a surface within the implantable optical sensor.
摘要翻译：可植入光学传感器和相关联的制造方法包括具有内表面和外表面的传感器外壳和形成在壳体中的窗口，该壳体在壳体内表面和壳体外表面之间延伸。封闭在壳体内并且具有光子表面的光电器件可操作地定位在窗口附近，用于通过窗口发射光或通过窗口检测光。光耦合构件位于光电器件和窗口之间，用于减少可植入光学传感器内的表面处的光反射。

7. 发明授权

US08396563B2 Clock synchronization in an implantable medical device system 有权
标题翻译：可植入医疗器械系统中的时钟同步
公开(公告)号：US08396563B2
公开(公告)日：2013-03-12
申请号：US12697070
申请日：2010-01-29
申请人： James D. Reinke , Robert M. Ecker , Kaustubh R. Patil , Michael B. Terry , Jonathan P. Roberts , Robert A. Corey
发明人： James D. Reinke , Robert M. Ecker , Kaustubh R. Patil , Michael B. Terry , Jonathan P. Roberts , Robert A. Corey
IPC分类号： A61N1/36 , A61N1/378
CPC分类号： G06F1/12 , A61N1/37288 , G06F1/06
摘要： This disclosure is directed to the synchronization of clocks of a secondary implantable medical device (IMD) to a clock of a primary IMD. The secondary IMD includes a communications clock. The communications clock may be synchronized based on at least one received communications pulse. The secondary IMD further includes a general purpose clock different than the communications clock. The general purpose clock may be synchronized based on at least one received power pulse. The communications clock may also be synchronized based on the at least one received power pulse.
摘要翻译：本公开涉及二次可植入医疗装置（IMD）的时钟与主IMD的时钟的同步。辅助IMD包括通信时钟。通信时钟可以基于至少一个接收到的通信脉冲来同步。次级IMD还包括与通信时钟不同的通用时钟。可以基于至少一个接收的功率脉冲同步通用时钟。通信时钟也可以基于至少一个接收的功率脉冲来同步。

8. 发明申请

US20110190850A1 CLOCK SYNCHRONIZATION IN AN IMPLANTABLE MEDICAL DEVICE SYSTEM 有权
标题翻译：可插入医疗设备系统中的时钟同步
公开(公告)号：US20110190850A1
公开(公告)日：2011-08-04
申请号：US12697070
申请日：2010-01-29
申请人： James D. Reinke , Robert M. Ecker , Kaustubh R. Patil , Michael B. Terry , Jonathan P. Roberts , Robert A. Corey
发明人： James D. Reinke , Robert M. Ecker , Kaustubh R. Patil , Michael B. Terry , Jonathan P. Roberts , Robert A. Corey
IPC分类号： A61N1/08
CPC分类号： G06F1/12 , A61N1/37288 , G06F1/06
摘要： This disclosure is directed to the synchronization of clocks of a secondary implantable medical device (IMD) to a clock of a primary IMD. The secondary IMD includes a communications clock. The communications clock may be synchronized based on at least one received communications pulse. The secondary IMD further includes a general purpose clock different than the communications clock. The general purpose clock may be synchronized based on at least one received power pulse. The communications clock may also be synchronized based on the at least one received power pulse.
摘要翻译：本公开涉及二次可植入医疗装置（IMD）的时钟与主IMD的时钟的同步。辅助IMD包括通信时钟。通信时钟可以基于至少一个接收到的通信脉冲来同步。次级IMD还包括与通信时钟不同的通用时钟。可以基于至少一个接收的功率脉冲同步通用时钟。通信时钟也可以基于至少一个接收的功率脉冲来同步。

9. 发明授权

US06788973B2 Apparatus and method to discriminate between telemetry downlink signals and noise in an implanted device 有权
标题翻译：用于区分遥测下行链路信号和植入设备中的噪声的装置和方法
公开(公告)号：US06788973B2
公开(公告)日：2004-09-07
申请号：US10117550
申请日：2002-04-02
申请人： Timothy J. Davis , Robert M. Ecker , James D. Reinke , John D. Wahlstrand
发明人： Timothy J. Davis , Robert M. Ecker , James D. Reinke , John D. Wahlstrand
IPC分类号： A61N137
CPC分类号： A61N1/37211 , A61N1/3718 , A61N1/37223 , A61N1/37276
摘要： An implanted medical device (IMD) conserves power by discriminating received radio frequency (RF) signals between noise and data based on frequency. Data is processed while noise is attenuated. The IMD operates in a first, relatively low, power mode while not receiving the RF signals, in a second, higher, power mode responsive to receiving RF signals, and operates in still higher power mode when the RF signals' average frequency over a selected period is within a predetermined range. A receiver circuit receives RF signals and discriminates a data signal from noise based on average frequency of the RF signals over selected time periods. The receiver circuit operates in a power-conserving mode unless it receives RF signals, or otherwise operates in a relatively higher-power mode. The receiver transfers signals to a telemetry circuit that operates in a power-conserving mode until it receives a valid data signal to operate in higher power mode.
摘要翻译：植入式医疗设备（IMD）通过基于频率鉴别噪声和数据之间的接收射频（RF）信号来节省功率。在噪声衰减时处理数据。 IMD在第一个相对较低的功率模式下工作，而不响应于接收RF信号而在第二较高功率模式中接收RF信号，并且当RF信号在所选择的频率上的平均频率期间在预定范围内。接收机电路接收RF信号，并根据选定时间段内的RF信号的平均频率，将数据信号与噪声区分开。接收器电路在功率节省模式下工作，除非它接收RF信号，否则以较高功率模式工作。接收机将信号传送到工作在省电模式的遥测电路，直到接收到有效的数据信号以在较高功率模式下工作。

10. 发明授权

US08170650B2 Implantable tissue perfusion sensing system and method 有权
标题翻译：植入式组织灌注感应系统及方法
公开(公告)号：US08170650B2
公开(公告)日：2012-05-01
申请号：US12039242
申请日：2008-02-28
申请人： Can Cinbis , James K. Carney , William T. Donofrio , Robert M. Ecker
发明人： Can Cinbis , James K. Carney , William T. Donofrio , Robert M. Ecker
IPC分类号： A61B6/00
CPC分类号： A61B5/1459 , A61B5/0059 , A61B5/024 , A61B5/046 , A61B5/0464 , A61B5/14542 , A61B5/7214 , A61N1/3925
摘要： A medical device for sensing cardiac events that includes a plurality of light sources capable of emitting light at a plurality of wavelengths, and a detector to detect the emitted light. A processor generates an ambient light measurement in response to ambient light detected by the detector, generates a plurality of light measurements in response to the emitted light detected by the detector, and adjusts the plurality of light measurements in response to the ambient light measurement.
摘要翻译：一种用于感测心脏事件的医疗装置，其包括能够发射多个波长的光的多个光源，以及检测器，用于检测发射的光。处理器响应于由检测器检测到的环境光产生环境光测量，响应于由检测器检测到的发射光产生多个光测量，并且响应于环境光测量来调整多个光测量。

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