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1. 发明申请

US20090270953A1 Optical Device 有权
标题翻译：光学设备
公开(公告)号：US20090270953A1
公开(公告)日：2009-10-29
申请号：US12107921
申请日：2008-04-23
申请人： Robert M. Ecker , Jonathan L. Kuhn , James D. Reinke , Can Cinbis , Timothy J. Davis , Paul F. Gerrish , Jonathan P. Roberts
发明人： Robert M. Ecker , Jonathan L. Kuhn , James D. Reinke , Can Cinbis , Timothy J. Davis , Paul F. Gerrish , Jonathan P. Roberts
IPC分类号： A61N5/06 , H01L31/12
CPC分类号： A61B5/0086 , A61B2562/028 , A61N1/3621 , A61N1/36557 , A61N1/375 , A61N1/3956
摘要： A reflectance-type optical sensor includes one or more photodiodes formed in a semiconductor substrate. A well having sidewalls and a bottom is formed in the top surface of the substrate, and a reflective layer is formed on the sidewalls and bottom. A light-emitting diode (LED) is mounted in the well, so that light emitted laterally and rearwardly from the LED strikes the sidewalls or bottom and is redirected in a direction generally perpendicular to the top surface of the substrate. The optical sensor can be fabricated using microelectromechanical systems (MEMS) fabrication techniques.
摘要翻译：反射型光学传感器包括在半导体衬底中形成的一个或多个光电二极管。在衬底的顶表面中形成具有侧壁和底部的阱，并且在侧壁和底部上形成反射层。发光二极管（LED）安装在井中，使得从LED侧向和向后发射的光撞击侧壁或底部，并且在大体上垂直于衬底的顶表面的方向上重定向。光学传感器可以使用微机电系统（MEMS）制造技术来制造。

2. 发明授权

US08452402B2 Optical sensing device for use in a medical device 有权
标题翻译：用于医疗设备的光学感测装置
公开(公告)号：US08452402B2
公开(公告)日：2013-05-28
申请号：US12107921
申请日：2008-04-23
申请人： Robert M. Ecker , Jonathan L. Kuhn , James D. Reinke , Can Cinbis , Timothy J. Davis , Paul F. Gerrish , Jonathan P. Roberts
发明人： Robert M. Ecker , Jonathan L. Kuhn , James D. Reinke , Can Cinbis , Timothy J. Davis , Paul F. Gerrish , Jonathan P. Roberts
IPC分类号： A61B5/1455
CPC分类号： A61B5/0086 , A61B2562/028 , A61N1/3621 , A61N1/36557 , A61N1/375 , A61N1/3956
摘要： A reflectance-type optical sensor includes one or more photodiodes formed in a semiconductor substrate. A well having sidewalls and a bottom is formed in the top surface of the substrate, and a reflective layer is formed on the sidewalls and bottom. A light-emitting diode (LED) is mounted in the well, so that light emitted laterally and rearwardly from the LED strikes the sidewalls or bottom and is redirected in a direction generally perpendicular to the top surface of the substrate. The optical sensor can be fabricated using microelectromechanical systems (MEMS) fabrication techniques.
摘要翻译：反射型光学传感器包括在半导体衬底中形成的一个或多个光电二极管。在衬底的顶表面中形成具有侧壁和底部的阱，并且在侧壁和底部上形成反射层。发光二极管（LED）安装在井中，使得从LED侧向和向后发射的光撞击侧壁或底部，并且在大体上垂直于衬底的顶表面的方向上重定向。光学传感器可以使用微机电系统（MEMS）制造技术来制造。

3. 发明申请

US20100185262A1 CO-LOCATION OF EMITTERS AND DETECTORS AND METHOD OF OPERATION 有权
标题翻译：发射器和探测器的合作位置及其操作方法
公开(公告)号：US20100185262A1
公开(公告)日：2010-07-22
申请号：US12690957
申请日：2010-01-21
申请人： Jonathan L. Kuhn , Jonathan P. Roberts , Andrew J. Ries , James D. Reinke , Jeffrey M. Jelen , Robert M. Ecker , Timothy J. Davis , Can Cinbis , Thomas A. Anderson
发明人： Jonathan L. Kuhn , Jonathan P. Roberts , Andrew J. Ries , James D. Reinke , Jeffrey M. Jelen , Robert M. Ecker , Timothy J. Davis , Can Cinbis , Thomas A. Anderson
IPC分类号： A61N1/08 , A61B5/00
CPC分类号： A61B5/1459 , A61B5/14542 , A61B5/1495 , A61B2562/0233 , A61B2562/046 , A61N1/36557 , G06F19/00 , G16H40/63
摘要： An implantable medical device having an optical sensor selects the function of modular opto-electronic assemblies included in the optical sensor. Each assembly is provided with at least one light emitting device and at least one light detecting device. A device controller coupled to the optical sensor controls the function of each the assemblies. The controller executes a sensor performance test and selects at least one of the plurality of assemblies to operate as a light emitting assembly in response to a result of the performance test. The controller selects at least one other of the plurality of optical sensor assemblies to operate as a light detecting assembly in response to a result of the performance test
摘要翻译：具有光学传感器的可植入医疗装置选择包括在光学传感器中的模块化光电组件的功能。每个组件设置有至少一个发光装置和至少一个光检测装置。耦合到光学传感器的设备控制器控制每个组件的功能。控制器执行传感器性能测试，并且响应于性能测试的结果，选择多个组件中的至少一个作为发光组件进行操作。响应于性能测试的结果，控制器选择多个光学传感器组件中的至少另一个作为光检测组件进行操作

4. 发明授权

US08275435B2 Co-location of emitters and detectors and method of operation 有权
标题翻译：发射器和探测器的共同定位和操作方法
公开(公告)号：US08275435B2
公开(公告)日：2012-09-25
申请号：US12690957
申请日：2010-01-21
申请人： Jonathan L. Kuhn , Jonathan P. Roberts , Andrew J. Ries , James D. Reinke , Jeffrey M. Jelen , Robert M. Ecker , Timothy J. Davis , Can Cinbis , Thomas A. Anderson
发明人： Jonathan L. Kuhn , Jonathan P. Roberts , Andrew J. Ries , James D. Reinke , Jeffrey M. Jelen , Robert M. Ecker , Timothy J. Davis , Can Cinbis , Thomas A. Anderson
IPC分类号： A61B5/00
CPC分类号： A61B5/1459 , A61B5/14542 , A61B5/1495 , A61B2562/0233 , A61B2562/046 , A61N1/36557 , G06F19/00 , G16H40/63
摘要： An implantable medical device having an optical sensor selects the function of modular opto-electronic assemblies included in the optical sensor. Each assembly is provided with at least one light emitting device and at least one light detecting device. A device controller coupled to the optical sensor controls the function of each the assemblies. The controller executes a sensor performance test and selects at least one of the plurality of assemblies to operate as a light emitting assembly in response to a result of the performance test. The controller selects at least one other of the plurality of optical sensor assemblies to operate as a light detecting assembly in response to a result of the performance test.
摘要翻译：具有光学传感器的可植入医疗装置选择包括在光学传感器中的模块化光电组件的功能。每个组件设置有至少一个发光装置和至少一个光检测装置。耦合到光学传感器的设备控制器控制每个组件的功能。控制器执行传感器性能测试，并且响应于性能测试的结果，选择多个组件中的至少一个作为发光组件进行操作。响应于性能测试的结果，控制器选择多个光学传感器组件中的至少一个以作为光检测组件进行操作。

5. 发明申请

US20090156912A1 IMPLANTABLE OPTICAL SENSOR AND METHOD FOR MANUFACTURE 有权
标题翻译：可植入的光学传感器及其制造方法
公开(公告)号：US20090156912A1
公开(公告)日：2009-06-18
申请号：US11955056
申请日：2007-12-12
申请人： Jonathan L. Kuhn , Timothy J. Davis , Can Cinbis , Robert M. Ecker , Shawn D. Knowles
发明人： Jonathan L. Kuhn , Timothy J. Davis , Can Cinbis , Robert M. Ecker , Shawn D. Knowles
IPC分类号： A61B5/1459 , H01L31/18
CPC分类号： A61B5/14542 , A61B5/0084 , A61B5/0086 , A61B5/14532 , A61B5/14552 , A61B5/1459 , A61B5/6846 , A61B2562/02 , A61B2562/043 , A61B2562/146
摘要： An implantable optical sensor and associated manufacturing method include a sensor housing having an inner surface and an outer surface and a window formed in the housing extending between the housing inner surface and the housing outer surface. An opto-electronic device enclosed within the housing and having a photonic surface is operatively positioned proximate the window for emitting light through the window or detecting light through the window. An optical coupling member is positioned between the opto-electronic device and the window for reducing light reflection at a surface within the implantable optical sensor.
摘要翻译：可植入光学传感器和相关联的制造方法包括具有内表面和外表面的传感器外壳和形成在壳体中的窗口，该壳体在壳体内表面和壳体外表面之间延伸。封闭在壳体内并且具有光子表面的光电器件可操作地定位在窗口附近，用于通过窗口发射光或通过窗口检测光。光耦合构件位于光电器件和窗口之间，用于减少可植入光学传感器内的表面处的光反射。

6. 发明授权

US08275432B2 Implantable optical sensor and method for manufacture 有权
标题翻译：植入式光学传感器及其制造方法
公开(公告)号：US08275432B2
公开(公告)日：2012-09-25
申请号：US11955056
申请日：2007-12-12
申请人： Jonathan L. Kuhn , Timothy J. Davis , Can Cinbis , Robert M. Ecker , Shawn D. Knowles , Thomas A. Anderson , Jeffrey M. Jelen
发明人： Jonathan L. Kuhn , Timothy J. Davis , Can Cinbis , Robert M. Ecker , Shawn D. Knowles , Thomas A. Anderson , Jeffrey M. Jelen
IPC分类号： A61B5/1455
CPC分类号： A61B5/14542 , A61B5/0084 , A61B5/0086 , A61B5/14532 , A61B5/14552 , A61B5/1459 , A61B5/6846 , A61B2562/02 , A61B2562/043 , A61B2562/146
摘要： An implantable optical sensor and associated manufacturing method include a sensor housing having an inner surface and an outer surface and a window formed in the housing extending between the housing inner surface and the housing outer surface. An opto-electronic device enclosed within the housing and having a photonic surface is operatively positioned proximate the window for emitting light through the window or detecting light through the window. An optical coupling member is positioned between the opto-electronic device and the window for reducing light reflection at a surface within the implantable optical sensor.
摘要翻译：可植入光学传感器和相关联的制造方法包括具有内表面和外表面的传感器外壳和形成在壳体中的窗口，该壳体在壳体内表面和壳体外表面之间延伸。封闭在壳体内并且具有光子表面的光电器件可操作地定位在窗口附近，用于通过窗口发射光或通过窗口检测光。光耦合构件位于光电器件和窗口之间，用于减少可植入光学传感器内的表面处的光反射。

7. 发明授权

US08515559B2 Communication dipole for implantable medical device 有权
标题翻译：用于可植入医疗器械的通信偶极子
公开(公告)号：US08515559B2
公开(公告)日：2013-08-20
申请号：US13359886
申请日：2012-01-27
申请人： Jonathan P. Roberts , Can Cinbis , David J. Peichel , James C. Allan , James D. Reinke , Kamal Deep Mothilal , Erik Griswold , George Patras
发明人： Jonathan P. Roberts , Can Cinbis , David J. Peichel , James C. Allan , James D. Reinke , Kamal Deep Mothilal , Erik Griswold , George Patras
IPC分类号： A61N1/00
CPC分类号： A61N1/37205 , A61B5/0028 , A61B5/0031 , A61B5/0215 , A61B5/6876 , A61B5/6882 , A61B2562/0247 , A61N1/37217 , H04B13/005
摘要： This disclosure is directed to an implantable medical device having a communication dipole configured in accordance with the techniques described herein. In one example, the disclosure is directed to an implantable medical device comprising a housing that encloses at least a communication module, a first electrode of a communication dipole electrically coupled to the communication module and an electrically conductive fixation mechanism that is electrically coupled to a portion of the housing and wherein a portion of the fixation mechanism is configured to function as at least part of a second electrode of the communication dipole. The electrically conductive fixation mechanism includes a dielectric material that covers at least part of a surface of the fixation mechanism. The communication module is configured to transmit or receive a modulated signal between the first electrode and second electrode of the communication dipole.
摘要翻译：本公开涉及具有根据本文所描述的技术配置的通信偶极子的可植入医疗装置。在一个示例中，本公开涉及可植入医疗装置，其包括壳体，该壳体至少包围通信模块，电耦合到通信模块的通信偶极子的第一电极和电连接到通信模块的部分的导电固定机构并且其中所述固定机构的一部分被配置为用作所述通信偶极子的第二电极的至少一部分。导电固定机构包括覆盖固定机构的表面的至少一部分的电介质材料。通信模块被配置为在通信偶极子的第一电极和第二电极之间发送或接收调制信号。

8. 发明申请

US20120197350A1 COMMUNICATION DIPOLE FOR IMPLANTABLE MEDICAL DEVICE 有权
标题翻译：用于可植入医疗器械的通信用DIPOLE
公开(公告)号：US20120197350A1
公开(公告)日：2012-08-02
申请号：US13359886
申请日：2012-01-27
申请人： Jonathan P. Roberts , Can Cinbis , David J. Peichel , James C. Allan , James D. Reinke , Kamal Deep Mothilal , Erik Griswold , George Patras
发明人： Jonathan P. Roberts , Can Cinbis , David J. Peichel , James C. Allan , James D. Reinke , Kamal Deep Mothilal , Erik Griswold , George Patras
IPC分类号： A61N1/08
CPC分类号： A61N1/37205 , A61B5/0028 , A61B5/0031 , A61B5/0215 , A61B5/6876 , A61B5/6882 , A61B2562/0247 , A61N1/37217 , H04B13/005
摘要： This disclosure is directed to an implantable medical device having a communication dipole configured in accordance with the techniques described herein. In one example, the disclosure is directed to an implantable medical device comprising a housing that encloses at least a communication module, a first electrode of a communication dipole electrically coupled to the communication module and an electrically conductive fixation mechanism that is electrically coupled to a portion of the housing and wherein a portion of the fixation mechanism is configured to function as at least part of a second electrode of the communication dipole. The electrically conductive fixation mechanism includes a dielectric material that covers at least part of a surface of the fixation mechanism. The communication module is configured to transmit or receive a modulated signal between the first electrode and second electrode of the communication dipole.
摘要翻译：本公开涉及具有根据本文所描述的技术配置的通信偶极子的可植入医疗装置。在一个示例中，本公开涉及可植入医疗装置，其包括壳体，该壳体至少包围通信模块，电耦合到通信模块的通信偶极子的第一电极和电连接到通信模块的部分的导电固定机构并且其中所述固定机构的一部分被配置为用作所述通信偶极子的第二电极的至少一部分。导电固定机构包括覆盖固定机构的表面的至少一部分的电介质材料。通信模块被配置为在通信偶极子的第一电极和第二电极之间发送或接收调制信号。

9. 发明授权

US10179242B2 Tissue oxygenation monitoring in heart failure 有权
公开(公告)号：US10179242B2
公开(公告)日：2019-01-15
申请号：US12797815
申请日：2010-06-10
申请人： Can Cinbis , James K. Carney , Jonathan L. Kuhn , David A. Anderson
发明人： Can Cinbis , James K. Carney , Jonathan L. Kuhn , David A. Anderson
IPC分类号： A61N1/36 , A61B5/145 , A61N1/365
摘要： A medical device for monitoring delivery of a therapy that includes a therapy delivery module to deliver a therapy, a controller to set a therapy delivery control parameter, an optical sensor to produce a signal corresponding to tissue light attenuation, and a processor configured to compute a tissue oxygenation measurement from the optical sensor signal, wherein the controller, the optical sensor, and the processor operate cooperatively to determine a setting of the therapy delivery control parameter corresponding to a maximum tissue oxygenation.

10. 发明授权

US08571620B2 Tissue oxygenation monitoring in heart failure 有权
标题翻译：心力衰竭组织氧合监测
公开(公告)号：US08571620B2
公开(公告)日：2013-10-29
申请号：US12797816
申请日：2010-06-10
申请人： Can Cinbis , James K. Carney , Jonathan L. Kuhn , David A. Anderson
发明人： Can Cinbis , James K. Carney , Jonathan L. Kuhn , David A. Anderson
IPC分类号： A61B5/00
CPC分类号： A61N1/36557
摘要： A medical device system and associated method are used for monitoring a heart failure patient. A medical device for monitoring delivery of a therapy includes a sensor sensing an optical sensor signal corresponding to light attenuation by a volume of body tissue of a patient, a therapy delivery module to deliver a therapy, and a processor configured to compute a first tissue oxygenation measurement from the optical sensor signal prior to initiating delivery of the therapy, compute a second tissue oxygenation measurement from the optical sensor signal subsequent to initiating delivery of the therapy, compare the first and the second tissue oxygenation measurements, and determine whether the delivered therapy was successful in response to the first tissue oxygenation measurement and the second tissue oxygenation measurement.
摘要翻译：医疗器械系统和相关方法用于监测心力衰竭患者。用于监测治疗递送的医疗装置包括传感器，其感测对应于患者的身体组织的体积的光衰减的光学传感器信号，用于递送治疗的治疗递送模块和被配置为计算第一组织氧合的处理器在开始递送治疗之前从光学传感器信号进行的测量，在开始递送治疗之后从光学传感器信号计算第二组织氧合测量，比较第一和第二组织氧合测量，并确定递送的治疗是否为成功地响应于第一次组织氧合测量和第二次组织氧合测量。

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