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1. 发明申请

US20150038584A1 MATERIALS FOR DISINFECTION PRODUCED BY NON-THERMAL PLASMA 有权
标题翻译：非热等离子体消毒材料
公开(公告)号：US20150038584A1
公开(公告)日：2015-02-05
申请号：US13813750
申请日：2011-08-03
申请人： Gregory Fridman , Sin Park , Natalie Shainsky , Danil V. Dobrynin , Alexander Rabinovich , Gennady Friedman , Alexander Fridman , Moogega Cooper , Ari D. Brooks , Suresh G. Joshi , Alexander E. Poor , Utku K. Ercan , Mark Ingerman
发明人： Gregory Fridman , Sin Park , Natalie Shainsky , Danil V. Dobrynin , Alexander Rabinovich , Gennady Friedman , Alexander Fridman , Moogega Cooper , Ari D. Brooks , Suresh G. Joshi , Alexander E. Poor , Utku K. Ercan , Mark Ingerman
IPC分类号： A01N37/30 , A61L2/16
CPC分类号： A01N37/46 , A01N37/30 , A01N43/16 , A01N61/00 , A61L2/0011 , A61L2/14 , A61L2/16 , A61L2/22 , A61L2202/24 , A01N25/02 , A01N25/34
摘要： Aspects of the present subject matter are directed to a method comprising contacting an fluid, optionally containing an added organic material, with a non-thermal plasma to form a disinfection composition, wherein the disinfection composition is a liquid, and contacting a surface with the disinfection composition, wherein the surface is at least partially disinfected upon contact with the disinfection composition. Additional aspects of the present subject matter are directed to a method comprising forming a disinfection composition by contacting an organic material with a non-thermal plasma, wherein the disinfection composition is a liquid. A further aspect of the present subject matter is directed to a disinfection composition comprising an organic material contacted by a non-thermal plasma, wherein the disinfection composition is a liquid.
摘要翻译：本发明的方面涉及一种方法，其包括将任选地含有加入的有机材料的流体与非热等离子体接触以形成消毒组合物，其中消毒组合物是液体，并使表面与消毒接触组合物，其中所述表面在与消毒组合物接触时至少部分消毒。本发明的另外的方面涉及包括通过使有机材料与非热等离子体接触来形成消毒组合物的方法，其中消毒组合物是液体。本发明的另一方面涉及包含与非热等离子体接触的有机材料的消毒组合物，其中消毒组合物是液体。

2. 发明申请

US20150025418A1 SYSTEM AND METHOD FOR EVALUATING TISSUE 审中-公开
标题翻译：用于评估组织的系统和方法
公开(公告)号：US20150025418A1
公开(公告)日：2015-01-22
申请号：US14465520
申请日：2014-08-21
申请人： Wan Y. SHIH , Wei-Heng SHIH , Hakki YEGINGIL , Ari D. BROOKS
发明人： Wan Y. SHIH , Wei-Heng SHIH , Hakki YEGINGIL , Ari D. BROOKS
IPC分类号： A61B5/00
CPC分类号： A61B5/0053 , A61B5/4244 , A61B5/4312 , A61B5/4381 , A61B5/441 , A61B5/442 , A61B8/085 , A61B8/403 , A61B8/485 , G01N29/0672 , G01N2291/02475 , G01N2291/02827
摘要： A sensor system for measuring an elastic modulus and a shear modulus and a method for evaluating a tissue. The invention pertains to a method for determining the presence of and/or characterizing abnormal growths, using a piezoelectric finger sensor (PEFS) system. The PEFS system may be particularly useful for screening for tumors and various forms of cancer. Additionally, the PEFS system may be useful for various dermatological applications.
摘要翻译：用于测量弹性模量和剪切模量的传感器系统和用于评估组织的方法。本发明涉及使用压电手指传感器（PEFS）系统确定异常生长的存在和/或表征异常生长的方法。 PEFS系统可能特别适用于筛选肿瘤和各种形式的癌症。此外，PEFS系统可用于各种皮肤病学应用。

3. 发明申请

US20130236972A1 Liver Sinusoid Model 审中-公开
标题翻译：肝正弦模型
公开(公告)号：US20130236972A1
公开(公告)日：2013-09-12
申请号：US13413679
申请日：2012-03-07
申请人： Hongseok Noh , Michael Bouchard
发明人： Hongseok Noh , Michael Bouchard
IPC分类号： C12N5/071 , C12M3/00
CPC分类号： C12N5/067 , C12N2533/54 , C12N2535/00
摘要： A liver sinusoid model includes a generally planar substrate having first and second generally parallel microchannels formed therein. A microporous membrane is disposed between and separating the first and second generally parallel microchannels. A first layer of cells lines one side of the membrane in the first microchannel. The first layer of cells are all a first common cell type. A second layer of cells extends parallel to the first layer of cells in one of the first microchannel and the second microchannel. The second layer of cells is all of a second common cell type. A liver sinusoid bioreactor utilizing the inventive model is also disclosed.
摘要翻译：肝窦状模型包括具有在其中形成的第一和第二大致平行的微通道的大致平面的基底。微孔膜设置在第一和第二大致平行的微通道之间并分离。第一层细胞在第一微通道中排列膜的一侧。第一层细胞都是第一种细胞类型。细胞的第二层平行于第一微通道和第二微通道之一中的第一细胞层延伸。第二层细胞都是第二种细胞类型。还公开了利用本发明模型的肝窦状生物反应器。

4. 发明申请

US20110264117A1 TISSUE JOINING DEVICE AND INSTRUMENT FOR ENABLING USE OF A TISSUE JOINING DEVICE 审中-公开
标题翻译：组织接合装置和使用组织接合装置的仪器
公开(公告)号：US20110264117A1
公开(公告)日：2011-10-27
申请号：US12990725
申请日：2009-05-01
申请人： Bradley Edward Layton , Margaret A. Wheatley , Ari Brooks , Andrew J. Bohl , Daniel S. Frame
发明人： Bradley Edward Layton , Margaret A. Wheatley , Ari Brooks , Andrew J. Bohl , Daniel S. Frame
IPC分类号： A61B17/10 , A61B17/08
CPC分类号： A61B17/11 , A61B17/0643 , A61B17/1114 , A61B17/320016 , A61B2017/00473 , A61B2017/00893 , A61B2017/0648 , A61B2017/1135 , A61B2017/320052
摘要： A tissue joining device and a surgical instrument for employing the tissue joining device are provided. The tissue joining device may be designed such that a first member may be inserted into a second member in discrete increments so that two lumen structures can properly be combined.
摘要翻译：提供了一种用于使用组织接合装置的组织接合装置和外科器械。组织接合装置可以设计成使得第一构件可以以离散的增量插入到第二构件中，使得可以适当地组合两个内腔结构。

5. 发明申请

US20090099441A1 BRAIDED ELECTRODES 审中-公开
标题翻译： BRAIDED电极
公开(公告)号：US20090099441A1
公开(公告)日：2009-04-16
申请号：US12065697
申请日：2006-09-08
申请人： Simon Giszter , Frank K. Ko , Ubong Ime Udoekwere , Heejae Yang
发明人： Simon Giszter , Frank K. Ko , Ubong Ime Udoekwere , Heejae Yang
IPC分类号： A61N1/05 , A61B5/042
CPC分类号： A61N1/0529 , A61N1/0551 , Y10T29/49194
摘要： Electrodes for intracorporeal and other uses are provided. The invention features sterilizable, braided electrodes which are formed of or include conductive elements in electronic communication with a plurality of sites for electrical stimulation or sensing. Other active elements may be included in the braided electrodes.
摘要翻译：提供体内和其他用途的电极。本发明的特征在于可灭菌的编织电极，其由多个用于电刺激或感测的部位电连接形成或包括导电元件。编织电极中可以包括其它有源元件。

6. 发明申请

US20080318247A1 Biomarker for cardiac transplant rejection 审中-公开
标题翻译：心脏移植排斥的生物标志物
公开(公告)号：US20080318247A1
公开(公告)日：2008-12-25
申请号：US12080285
申请日：2008-04-02
申请人： Chang Chang , Howard J. Eisen
发明人： Chang Chang , Howard J. Eisen
IPC分类号： G01N33/53 , C12Q1/02
CPC分类号： G01N33/6893 , G01N2800/245
摘要： The invention provides a method of diagnosing a disease or disorder featuring an abnormal level of a ring-containing molecule in a tissue. In one embodiment, a method of diagnosing organ transplant rejection is provided.
摘要翻译：本发明提供一种以组织中含环分子异常水平为特征的疾病或病症的诊断方法。在一个实施例中，提供了一种诊断器官移植排斥的方法。

7. 发明申请

US20140058260A1 SYSTEM AND METHOD FOR EVALUATING TISSUE 有权
标题翻译：用于评估组织的系统和方法
公开(公告)号：US20140058260A1
公开(公告)日：2014-02-27
申请号：US14031307
申请日：2013-09-19
申请人： Wan Y. SHIH , Wei-Heng SHIH , Hakki YEGINGIL , Ari D. BROOKS
发明人： Wan Y. SHIH , Wei-Heng SHIH , Hakki YEGINGIL , Ari D. BROOKS
IPC分类号： A61B8/08 , A61B8/00
CPC分类号： A61B5/0053 , A61B5/4244 , A61B5/4312 , A61B5/4381 , A61B5/441 , A61B5/442 , A61B8/085 , A61B8/403 , A61B8/485 , G01N29/0672 , G01N2291/02475 , G01N2291/02827
摘要： The present invention provides a sensor system for measuring an elastic modulus and a shear modulus and a method for using the sensor system to evaluate a tissue by determining the presence of and/or characterizing abnormal growths. The method involves applying a set of forces of different magnitudes to one or more locations of tissue, detecting the corresponding displacements due to said applied forces, determining the forces acting on those locations of tissue which are a combination of forces from the applied voltages and the countering forces from tissue deformation, obtaining the elastic modulus and/or shear modulus for a plurality of locations, and determining abnormal growth invasiveness, malignancy or the presence of a tumor from said elastic and/or shear moduli.
摘要翻译：本发明提供了一种用于测量弹性模量和剪切模量的传感器系统，以及使用该传感器系统通过确定异常生长的存在和/或表征异常生长来评估组织的方法。该方法包括将一组不同大小的力施加到组织的一个或多个位置，检测由于所述施加的力引起的相应的位移，确定作用于组织的那些位置的力，其是来自所施加的电压和组织变形的抵抗力，获得多个位置的弹性模量和/或剪切模量，以及从所述弹性和/或剪切模量确定异常生长侵袭性，恶性肿瘤或肿瘤的存在。

8. 发明申请

US20110277618A1 METHOD AND APPARATUS FOR BRAIDING MICRO STRANDS 有权
标题翻译：消除微观结构的方法和装置
公开(公告)号：US20110277618A1
公开(公告)日：2011-11-17
申请号：US13129925
申请日：2009-11-19
申请人： Simon Giszter , Tae Gyo Kim , Arun Ramakrishnan
发明人： Simon Giszter , Tae Gyo Kim , Arun Ramakrishnan
IPC分类号： D04C1/00 , D04C3/00
CPC分类号： D04C3/42
摘要： A method and apparatus for fabricating microbraided structures is provided. A microbraiding device includes first and second carrier members that are movable with respect to each other. Each carrier includes a plurality of shelters. Spool-less strands of microfiber are retained in shuttles that are movable between the first and second shelters under magnetic forces. The microbraid structure is fabricated as the shuttles move between the first shelters, and as the first carrier member moves relative to the second carrier member.
摘要翻译：提供了一种用于制造微阵列结构的方法和装置。微型装置包括可相对于彼此移动的第一和第二承载构件。每个载体包括多个收容所。无纺布的超细纤维束被保留在可在磁力下在第一和第二收容所之间移动的梭子中。随着梭子在第一遮蔽物之间移动，并且当第一承载构件相对于第二承载构件移动时，制作微框架结构。

9. 发明申请

US20230038015A1 SYNTHESIS OF MXENE SUSPENSIONS WITH IMPROVED STABILITY 有权
公开(公告)号：US20230038015A1
公开(公告)日：2023-02-09
申请号：US17759289
申请日：2021-01-22
申请人： DREXEL UNIVERSITY
发明人： Tyler S. MATHIS , Yury GOGOTSI , Kathleen MALESKI
IPC分类号： C01B32/907 , H01B1/04
摘要： Provided are enhanced MXene materials made from MAX-phase precursors that comprise an excess of metal A. The resultant enhanced MXenes exhibit improved stability over periods of days and months, particularly when stored in aqueous media.

10. 发明申请

US20220402938A1 GLUTAMATE TRANSPORTER ACTIVATORS AND METHODS USING SAME 有权
公开(公告)号：US20220402938A1
公开(公告)日：2022-12-22
申请号：US17847490
申请日：2022-06-23
申请人： Drexel University
发明人： Sandhya Kortagere , Andreia C. K. Mortensen , Ole V. Mortensen , Joseph M. Salvino
IPC分类号： C07D495/04 , A61P25/28 , C07D401/14 , C07D403/04 , C07D405/14
摘要： The present invention provides compounds useful for treating, ameliorating or preventing a disease or disorder that is caused, induced or characterized by abnormal reduction in glutamate transporter activity or abnormal increase in extracellular CNS glutamate concentration in a subject. In certain embodiments, the compound stimulates a glutamate transporter.

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