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1. 发明申请

US20190250129A1 CHROMATOGRAPHY COLUMN 审中-公开
公开(公告)号：US20190250129A1
公开(公告)日：2019-08-15
申请号：US16343786
申请日：2017-08-01
申请人： JNC CORPORATION
发明人： Masami TODOKORO
IPC分类号： G01N30/56 , B01D15/22 , B01D15/20 , G01N30/60
CPC分类号： G01N30/56 , B01D15/206 , B01D15/22 , G01N30/60
摘要： A column mainly comprises a tube, a plug, a first filter, a second filter, a stopper, and a connector. The tube mainly comprises a bottomed cylindrical storage part, and a cylindrical bottom-side connection part connected to a bottom of the storage part. The storage part and the bottom-side connection part are coaxially provided. The plug mainly comprises an outer pipe coaxially provided, and an inner pipe provided on an inner side of the outer pipe. The first filter and the second filter each are such a filter as not to enable the filler to pass. The stopper mainly comprises a stopper gripping part, and a stopper insertion part. The connector mainly comprises a connector gripping part and a connector insertion part.

2. 发明申请

US20190234905A1 DETECTION APPARATUS AND DETECTION METHOD 审中-公开
公开(公告)号：US20190234905A1
公开(公告)日：2019-08-01
申请号：US16376986
申请日：2019-04-05
申请人： Nuctech Company Limited
发明人： Qingjun Zhang , Yuanjing Li , Zhiqiang Chen , Ziran Zhao , Yinong Liu , Yaohong Liu , Huishao He , Qiufeng Ma , Weiping Zhu , Xiang Zou , Jianping Chang , Song Liang
IPC分类号： G01N27/62 , H01J49/04 , G01N1/22 , G01N1/02 , G01N1/40
CPC分类号： G01N27/622 , G01N1/02 , G01N1/2211 , G01N1/405 , G01N1/42 , G01N30/60 , G01N30/722 , G01N2001/028 , H01J49/0422 , H01J49/0459 , H01J49/0468 , G01N30/6043 , G01N30/6078
摘要： A detection apparatus and a detection method are disclosed. In one aspect, the detection apparatus includes a sampling device for collecting samples to be checked. It further includes a sample pre-processing device configured to pre-process the sample from the sampling device. It further includes a sample analyzing device for separating samples from the pre-processing device and for analyzing the separated samples. The detection apparatus is miniaturized and highly precise, and is capable of quickly and accurately detecting gaseous phase or particulate substances, and it has applications for safety inspections at airports, ports, and subway stations.

3. 发明授权

US09983178B2 Chromatography column assembly 有权
公开(公告)号：US09983178B2
公开(公告)日：2018-05-29
申请号：US14238278
申请日：2012-08-23
申请人： Joseph D. Michienzi , Keith Fadgen , Wade P. Leveille, Sr. , Raymond P. Fisk , Frank John Marzalkowski, Jr.
发明人： Joseph D. Michienzi , Keith Fadgen , Wade P. Leveille, Sr. , Raymond P. Fisk , Frank John Marzalkowski, Jr.
IPC分类号： G01N30/60 , B01D15/10 , B01D15/22 , B05B5/16 , G01N30/72 , B01D15/18
CPC分类号： B05B5/16 , B01D15/10 , B01D15/1871 , B01D15/22 , G01N30/60 , G01N30/6004 , G01N30/6026 , G01N30/603 , G01N30/6039 , G01N30/6052 , G01N30/6095 , G01N30/7266 , Y10T29/49908
摘要： Described is a chromatography column assembly that includes a permanently deformable outer tube, an intermediate tube, an inner tube and a sorbent bed disposed within the inner tube. The sorbent bed may be in the form of packed chromatographic particles or a porous monolithic structure. A radial seal is provided by one or more uniform radial crimps at longitudinal locations on the assembly. The uniform radial crimp compresses the outer tube and underlying intermediate tube onto the inner tube to achieve a high pressure liquid tight seal between the three tubes. The length and depth of each crimp is accurately formed to accommodate the requirements of the particular application. Leakage along the tubing assembly is prevented and void volume is reduced or eliminated. No external ferrule or ferrule swaging mechanism is needed; therefore the chromatography column assembly is easily adapted for use in various chromatographic column configurations.

4. 发明授权

US09885692B2 Method for producing a chromatography-enrichment column 有权
公开(公告)号：US09885692B2
公开(公告)日：2018-02-06
申请号：US14414853
申请日：2013-07-02
申请人： COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES
发明人： Olivier Dellea , Pascal Fugier , Helene Marie , Severine Vignoud
IPC分类号： B05D3/06 , G01N30/60 , B05D3/14 , B05D1/20 , B05D1/00 , B01D53/04 , G01N30/02
CPC分类号： G01N30/60 , B01D53/0423 , B05D1/005 , B05D1/204 , B05D3/062 , B05D3/142 , B82Y30/00 , G01N30/08 , G01N2030/025
摘要： The invention concerns a method for producing a chromatography-enrichment column, the method comprising the following steps: (a) depositing at least one layer of desired particles, which may be identical or different, and are intended to constitute the stationary phase, in a compact assembly, on the flat surface of a substrate; (b) crosslinking the layer in at least the regions corresponding to the desired shape of the enrichment column to be obtained; (c) impregnating the layer with a light radiation-sensitive material; (d) insolating the layer obtained in step (c) so as to form insolated regions of which the shape corresponds to the desired internal shape of the enrichment column, if the light radiation-sensitive material behaves like a positive resin or to form non-insolated regions of which the shape corresponds to the desired internal shape of the enrichment column if the light radiation-sensitive material behaves like negative resin; and (e) eliminating the light radiation-sensitive material in the zones corresponding to the internal shape of the enrichment column. The invention is used in particular in the field of chemical analysis.

5. 发明授权

US09816647B2 Sealing element for a fluidic connection 有权
公开(公告)号：US09816647B2
公开(公告)日：2017-11-14
申请号：US14403503
申请日：2012-05-22
申请人： Thomas Reinhardt , Joachim-Richard Wagner
发明人： Thomas Reinhardt , Joachim-Richard Wagner
IPC分类号： F16L19/065 , F16J15/02 , F16L21/00 , G01N30/60 , G01N30/02
CPC分类号： F16L19/065 , F16J15/022 , F16L21/005 , G01N30/461 , G01N30/60 , G01N30/6026 , G01N30/6039 , G01N2030/027 , Y10T29/49826 , Y10T29/49872
摘要： A sealing element for sealing a fluidic connection between a coupling element and a tubular element and thereby providing a sealed flow path through the tubular element and between the coupling element and the tubular element in a longitudinal direction, the sealing element comprising: a recess extending in the longitudinal direction, the recess configured to receive the tubular element; a transverse wall defining an extent of the recess in the longitudinal direction, the transverse wall having a through hole.

6. 发明申请

US20170182488A1 SEGMENTABLE CONTAINER AND METHOD OF SEGMENTING SUBSTANCE CONTAINED IN CONTAINER 审中-公开
公开(公告)号：US20170182488A1
公开(公告)日：2017-06-29
申请号：US15456434
申请日：2017-03-10
申请人： SHIMADZU CORPORATION
发明人： Tetsuo Ohashi
IPC分类号： B01L3/00 , G01N30/60 , B65D17/00
CPC分类号： B01L3/502 , B01L3/5021 , B01L3/502784 , B01L3/52 , B01L2200/0668 , B01L2200/0689 , B01L2300/0838 , B01L2300/0858 , B01L2300/087 , B01L2400/0409 , B01L2400/043 , B65D17/00 , B65D17/04 , G01N30/60 , Y10T156/1005
摘要： Provided are a simple, quick, and low-processing cost method capable of reliably separating part of an accommodated substance accommodated in a vessel only by simple mechanical operation while maintaining a hermetically-sealed state without any contact with an outside atmosphere, as well as a vessel with which the method may be used. A separable vessel comprises a first vessel portion, a second vessel portion which is contiguous with the first vessel portion, a fracture-inducing portion formed between the first vessel portion and the second vessel portion, and a self-fusing material provided on an outer surface so as to cover the fracture-inducing portion; and may contain an accommodated substance therein.

7. 发明申请

US20170136416A1 FILTRATION DEVICE 审中-公开
公开(公告)号：US20170136416A1
公开(公告)日：2017-05-18
申请号：US15129440
申请日：2015-04-01
申请人： Sartorius Stedim Biotech GmbH
发明人： Martin Leuthold
IPC分类号： B01D65/00 , B01D63/10 , B01D63/08
CPC分类号： B01D65/003 , B01D15/20 , B01D15/22 , B01D63/082 , B01D63/10 , B01D2313/14 , B01J20/28035 , B01J20/28052 , B01J2220/80 , G01N30/60
摘要： A filtration device (1, 1′) has a housing (2, 2′) with an inlet (3, 3′) to supply fluid to be filtered and an outlet (4, 4′) to discharge filtered permeate. A filter module (5, 5′) is between the inlet and outlet and has membrane layers (9, 9′) connected to the housing (2, 2′) in a fluid-tight manner. An inflow channel (11, 11′) is at the inlet side (3, 3′) and an outflow channel (12, 12′) is at the outlet side (4, 4′). A compressible and flow-permeable intermediate layer (10, 10′) is arranged between at least two membrane layers (9, 9′). The intermediate layer (10, 10′) is made of a nonwoven material with: a thickness corresponding to 20 to 200% of the thickness of the membrane layers (9, 9′), a basis weight of 10 to 150 g/m2, and an air flow rate therethrough of 150 to 5000 L/(m2 * s).

8. 发明申请

US20170082584A1 FERRULE CONTAINER, AND FERRULE CONTAINER CONTAINING FERRULE 审中-公开
公开(公告)号：US20170082584A1
公开(公告)日：2017-03-23
申请号：US15310571
申请日：2014-05-15
申请人： Shimadzu Corporation
发明人： Hajime TAKEMOTO , Hirokazu TANIUCHI , Yoshihiko IDE , Masayuki OKADA , Yasunori TERAI
IPC分类号： G01N30/60 , B65D75/36 , B01D53/02 , B65D65/02
CPC分类号： G01N30/60 , B01D53/025 , B65D65/02 , B65D75/36 , G01N30/6034 , G01N30/6039 , G01N2030/025
摘要： A ferrule container 1 is provided with a ferrule accommodating part 11 and a first column guide part 12. A ferrule is accommodated in the ferrule accommodating part 11. The first column guide part 12 guides a column so as to insert the column into the ferrule accommodated in the ferrule accommodating part 11. Guiding of the column by the first column guide part 12 enables the column to be smoothly and reliably inserted into the ferrule accommodated in the ferrule accommodating part 11. Consequently, unlike a case in which an operator inserts a column while pinching a ferrule with hand, the work of inserting a column into a ferrule can easily be performed.

9. 发明授权

US09574232B2 Devices and methods for controlling reversible chemical reactions at solid-liquid interfaces by rapid preconcentration and phase replacement 有权
标题翻译：通过快速预浓缩和相替换来控制固 - 液界面的可逆化学反应的装置和方法
公开(公告)号：US09574232B2
公开(公告)日：2017-02-21
申请号：US14630623
申请日：2015-02-24
申请人： The Board of Trustees of the Leland Stanford Junior University
发明人： Crystal Han , Juan G. Santiago , Viktor Shkolnikov
IPC分类号： G01N27/447 , G01N27/00 , C12M1/34 , C12Q1/68 , G01N33/53 , C40B30/04 , C07H21/02 , C07H21/04 , G01N27/27 , C07K1/22 , G01N30/60
CPC分类号： C12Q1/6837 , C07K1/22 , C12Q1/6832 , G01N27/27 , G01N27/447 , G01N27/44704 , G01N27/44791 , G01N27/44795 , G01N30/60
摘要： Devices and methods for controlling reversible chemical reactions at solid-liquid interfaces are disclosed. In particular, the invention relates to a method of increasing reaction rates by concentrating a target molecule in a liquid phase in the region of a reactant or ligand immobilized on a solid followed by removal of the liquid phase and replacement with an immiscible phase, such as an immiscible gas or liquid to impede the reverse reaction. Devices for performing this method to increase the rates and degree of completion of kinetically limited ligand binding or nucleic acid hybridization reactions in affinity chromatography and microarray applications are also disclosed.
摘要翻译：公开了在固 - 液界面处控制可逆化学反应的装置和方法。特别地，本发明涉及通过将固定在固体上的反应物或配体的区域中的液相中的靶分子浓缩，然后除去液相并用不混溶相替代的方式来提高反应速率的方法，例如不混溶的气体或液体以阻止反向反应。还公开了用于执行该方法以提高亲和层析和微阵列应用中的动力学有限配体结合或核酸杂交反应的完成速率和完成程度的装置。

10. 发明申请

US20150233876A1 Method for producing a chromatography-enrichment column 有权
标题翻译：色谱富集柱的制备方法
公开(公告)号：US20150233876A1
公开(公告)日：2015-08-20
申请号：US14414853
申请日：2013-07-02
申请人： COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES
发明人： Olivier Dellea , Pascal Fugier , Hélène Marie , Séverine Vignoud
IPC分类号： G01N30/60 , B01D53/04 , B05D1/20 , B05D1/00 , B05D3/14 , B05D3/06
CPC分类号： G01N30/60 , B01D53/0423 , B05D1/005 , B05D1/204 , B05D3/062 , B05D3/142 , B82Y30/00 , G01N30/08 , G01N2030/025
摘要： The invention concerns a method for producing a chromatography-enrichment column, the method comprising the following steps: (a) depositing at least one layer of desired particles, which may be identical or different, and are intended to constitute the stationary phase, in a compact assembly, on the flat surface of a substrate; (b) crosslinking the layer in at least the regions corresponding to the desired shape of the enrichment column to be obtained; (c) impregnating the layer with a light radiation-sensitive material; (d) insolating the layer obtained in step (c) so as to form insolated regions of which the shape corresponds to the desired internal shape of the enrichment column, if the light radiation-sensitive material behaves like a positive resin or to form non-insolated regions of which the shape corresponds to the desired internal shape of the enrichment column if the light radiation-sensitive material behaves like negative resin; and (e) eliminating the light radiation-sensitive material in the zones corresponding to the internal shape of the enrichment column. The invention is used in particular in the field of chemical analysis.
摘要翻译：本发明涉及一种生产色谱 - 富集柱的方法，该方法包括以下步骤：（a）沉积至少一层可能相同或不同的期望的颗粒，并且旨在构成固定相紧凑的组装，在基底的平坦表面上; （b）在至少对应于要获得的富集柱的所需形状的区域中交联该层; （c）用光辐射敏感材料浸渍该层; （d）使步骤（c）中获得的层剥离，以形成其形状对应于富集柱的所需内部形状的绝缘区域，如果光辐射敏感材料表现得像正树脂或形成非 - 如果光辐射敏感材料表现为负树脂，则其形状对应于富集柱的期望内部形状的其它区域; 和（e）消除对应于浓缩塔的内部形状的区域中的光辐射敏感材料。本发明特别用于化学分析领域。

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