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1. 发明申请

US20180308674A1 MULTI DETECTOR MASS SPECTROMETER AND SPECTROMETRY METHOD FILTER 审中-公开
公开(公告)号：US20180308674A1
公开(公告)日：2018-10-25
申请号：US15752871
申请日：2016-08-11
申请人： Thermo Fisher Scientific (Bremen) GmbH , The University of Bristol
发明人： Johannes SCHWIETERS , Timothy Richard ELLIOTT , Christopher David COATH
IPC分类号： H01J49/02 , H01J49/00 , H01J49/10
CPC分类号： H01J49/025 , H01J49/0045 , H01J49/105 , H01J49/28
摘要： The present invention can be directed to a mass spectrometer, relevant parts thereof like replacement kits or upgrading kits and/or mass spectrometry methods. A mass spectrometer according to the present invention can comprise at least one ion source for generating a beam of ions from a sample. Moreover at least one mass filter downstream of the ion source can be provided and adapted to select ions from the beam by their mass-to-charge ratio (m/z). Furthermore at least one collision cell arranged downstream of the mass filter can be arranged. At least one sector field mass analyser arranged downstream of the collision cell can be further provided and at least one ion multicollector comprising a plurality of ion detectors arranged downstream of the mass analyser, for detecting a plurality of different ion species in parallel and/or simultaneously.

2. 发明授权

US08283626B2 Electron transfer dissociation device 有权
标题翻译：电子转移离解装置
公开(公告)号：US08283626B2
公开(公告)日：2012-10-09
申请号：US12937806
申请日：2009-04-03
申请人： Jeffery Mark Brown , Martin Raymond Green
发明人： Jeffery Mark Brown , Martin Raymond Green
IPC分类号： H01J49/26
CPC分类号： H01J49/28 , H01J49/0072 , H01J49/065
摘要： A mass spectrometer is disclosed comprising an Electron Transfer Dissociation device comprising an ion guide. A control system determines the degree of fragmentation and charge reduction of precursor ions within the ion guide and varies the speed at which ions are transmitted through the ion guide in order to optimise the fragmentation and charge reduction process.
摘要翻译：公开了一种质谱仪，其包括电子转移离解装置，其包括离子导向器。控制系统确定离子导向器内的前体离子的碎裂和电荷减少的程度，并且改变离子通过离子导向器传输的速度，以便优化碎裂和电荷还原过程。

3. 发明授权

US3831026A Plural beam mass spectrometer and method of conducting plural beam studies 失效
标题翻译：多光束质谱仪及其引导方法
公开(公告)号：US3831026A
公开(公告)日：1974-08-20
申请号：US25879372
申请日：1972-06-01
申请人： POWERS P
发明人： POWERS P
IPC分类号： H01J49/06 , H01J49/28 , H01J49/30 , H01J49/32 , H01L21/02 , H01J39/34
CPC分类号： H01J49/107 , H01J49/06 , H01J49/28 , H01J49/30 , H01J49/326 , H01L28/92
摘要： Plural ion beams emanating from one or more ion sources are conducted in multiplexed fashion through the magnetic analyzer of a mass spectrometer toward one or more collectors. In one embodiment, the beams traverse spaced paths and are received by separate collectors. In another embodiment, the beams are time division multiplexed along a common path and received by a single collector. The magnetic analyzer may be scanned during operation to simultaneously provide spectra for each of the beams and the mass spectral range of the beams compared.
摘要翻译：从一个或多个离子源发出的多个离子束以多种方式通过质谱仪的磁分析仪朝向一个或多个收集器进行。在一个实施例中，光束横穿间隔开的路径并且由分开的收集器接收。在另一个实施例中，波束沿着公共路径被时分复用并由单个收集器接收。可以在操作期间扫描磁分析仪以同时提供每个光束的光谱和所比较的光束的质谱范围。

4. 发明授权

US3370171A Exposure control system for a mass spectrometer responsive to the ion beam intensity 失效
标题翻译：用于质谱仪的离子束强度的曝光控制系统
公开(公告)号：US3370171A
公开(公告)日：1968-02-20
申请号：US42289365
申请日：1965-01-04
申请人： JEOL LTD
发明人： TOMIYOSHI OHTA
IPC分类号： H01J49/28
CPC分类号： H01J49/28

5. 发明授权

US2995659A Mass spectrometers 失效
公开(公告)号：US2995659A
公开(公告)日：1961-08-08
申请号：US342760
申请日：1960-01-19
申请人： ASS ELECT IND
发明人： DEREK CRAIG ROBERT
IPC分类号： H01J49/28
CPC分类号： H01J49/28

6. 发明申请

US20190057853A1 Floating Magnet For A Mass Spectrometer 审中-公开
公开(公告)号：US20190057853A1
公开(公告)日：2019-02-21
申请号：US16076385
申请日：2017-02-07
申请人： Luxembourg Institute Of Science And Technology (LIST)
发明人： Roch Andrzejewski , Rachid Barrahma , David Dowsett , Tom Wirtz
IPC分类号： H01J49/20 , H01J49/24
CPC分类号： H01J49/20 , H01J49/24 , H01J49/28
摘要： An electromagnet assembly suitable for mass spectrometer comprising one yoke; and two pole pieces; the pole pieces being comprised in a vacuum chamber and being separated from each other by a pole piece gap defining a passage for the charged particles to be deflected; the yoke forming a bridge over the two pole pieces thus defining a magnetic circuit. The electromagnet assembly further comprises one electrical circuit for generating a magnetic flux in the magnetic circuit, the electrical circuit being included in the yoke. The electromagnet assembly is remarkable in that the pole pieces are electrically insulated from the electrical circuit and from the yoke by first electrical insulating means and are electrically insulated from the vacuum chamber.

7. 发明申请

US20140042314A1 Electron Transfer Dissociation Device 有权
标题翻译：电子转移离解装置
公开(公告)号：US20140042314A1
公开(公告)日：2014-02-13
申请号：US14056622
申请日：2013-10-17
申请人： Micromass UK Limited
发明人： Jeffery Mark Brown , Martin Raymond Green
IPC分类号： H01J49/28
CPC分类号： H01J49/28 , H01J49/0072 , H01J49/065
摘要： A mass spectrometer is disclosed comprising an Electron Transfer Dissociation device comprising an ion guide. A control system determines the degree of fragmentation and charge reduction of precursor ions within the ion guide and varies the speed at which ions are transmitted through the ion guide in order to optimise the fragmentation and charge reduction process.
摘要翻译：公开了一种质谱仪，其包括电子转移离解装置，其包括离子导向器。控制系统确定离子导向器内的前体离子的碎裂和电荷减少的程度，并且改变离子通过离子导向器传输的速度，以便优化碎裂和电荷还原过程。

8. 发明授权

US08581184B2 Quadrupole mass spectrometer 有权
标题翻译：四极质谱仪
公开(公告)号：US08581184B2
公开(公告)日：2013-11-12
申请号：US13639474
申请日：2011-03-03
申请人： Shiro Mizutani
发明人： Shiro Mizutani
IPC分类号： H01J49/42
CPC分类号： H01J49/28 , H01J49/022 , H01J49/4215
摘要： Provided is a quadrupole mass spectrometer including direct-current voltage sources having response characteristics which ensure that the response time of the direct-current voltage will be shorter than the period of time required for an ion having the highest mass-to-charge ratio (m/z) among the ions introduced into a quadrupole mass filter to pass through this filter. Main rod electrodes and pre-rod electrodes are connected to each other via primary differentiation circuits. Thus, in the transient state of the voltage change due to the switching of the mass-to-charge ratio, among the ions entering the quadrupole mass filter, ions having low m/z values can be removed by a pre-electrode unit, and ions having high m/z values can be removed by a main electrode unit. Accordingly, a large amount of ions can be prevented from passing through the filter and entering an ion detector.
摘要翻译：提供了一种四极质谱仪，其包括具有响应特性的直流电压源，其确保直流电压的响应时间将短于具有最高质荷比的离子所需的时间（m / z）引入四极质量过滤器中的离子通过该过滤器。主杆电极和预棒电极通过一次微分电路相互连接。因此，在由质荷比的切换引起的电压变化的瞬态中，在进入四极质量过滤器的离子中，通过预电极单元可以除去具有低m / z值的离子，可以通过主电极单元去除具有高m / z值的离子。因此，可以防止大量的离子通过过滤器并进入离子检测器。

9. 发明申请

US20130234018A1 Quadrupole Mass Spectrometer 有权
标题翻译：四极质谱仪
公开(公告)号：US20130234018A1
公开(公告)日：2013-09-12
申请号：US13639474
申请日：2011-03-03
申请人： SHIMADZU CORPORATION
发明人： Shiro Mizutani
IPC分类号： H01J49/28
CPC分类号： H01J49/28 , H01J49/022 , H01J49/4215
摘要： Provided is a quadrupole mass spectrometer including direct-current voltage sources having response characteristics which ensure that the response time of the direct-current voltage will be shorter than the period of time required for an ion having the highest mass-to-charge ratio (m/z) among the ions introduced into a quadrupole mass filter to pass through this filter. Main rod electrodes and pre-rod electrodes are connected to each other via primary differentiation circuits. Thus, in the transient state of the voltage change due to the switching of the mass-to-charge ratio, among the ions entering the quadrupole mass filter, ions having low m/z values can be removed by a pre-electrode unit, and ions having high m/z values can be removed by a main electrode unit. Accordingly, a large amount of ions can be prevented from passing through the filter and entering an ion detector.
摘要翻译：提供了一种四极质谱仪，其包括具有响应特性的直流电压源，其确保直流电压的响应时间将短于具有最高质荷比的离子所需的时间（m / z）引入四极质量过滤器中的离子通过该过滤器。主杆电极和预棒电极通过一次微分电路相互连接。因此，在由质荷比的切换引起的电压变化的瞬态中，在进入四极质量过滤器的离子中，通过预电极单元可以除去具有低m / z值的离子，可以通过主电极单元去除具有高m / z值的离子。因此，可以防止大量的离子通过过滤器并进入离子检测器。

10. 发明申请

US20110062323A1 Electron Transfer Dissociation Device 有权
标题翻译：电子转移离解装置
公开(公告)号：US20110062323A1
公开(公告)日：2011-03-17
申请号：US12937806
申请日：2009-04-03
申请人： Jeffery Mark Brown , Martin Raymond Green
发明人： Jeffery Mark Brown , Martin Raymond Green
IPC分类号： H01J49/00 , H01J49/06
CPC分类号： H01J49/28 , H01J49/0072 , H01J49/065
摘要： A mass spectrometer is disclosed comprising an Electron Transfer Dissociation device comprising an ion guide. A control system determines the degree of fragmentation and charge reduction of precursor ions within the ion guide and varies the speed at which ions are transmitted through the ion guide in order to optimise the fragmentation and charge reduction process.
摘要翻译：公开了一种质谱仪，其包括电子转移离解装置，其包括离子导向器。控制系统确定离子导向器内的前体离子的碎裂和电荷减少的程度，并且改变离子通过离子导向器传输的速度，以便优化碎裂和电荷还原过程。

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