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1. 发明申请

US20230133142A1 PATIENT STRATIFICATION AND CLINICAL DECISION SUPPORT ON MECHANICAL VENTILATION SETTINGS FROM SONAR RESPONSES THROUGH AN ENDOTRACHEAL TUBE (ETT) 有权
公开(公告)号：US20230133142A1
公开(公告)日：2023-05-04
申请号：US17960167
申请日：2022-10-05
申请人： Rafael Wiemker , Joerg Sabczynski , Thomas Koehler , Cornelis Petrus Hendriks , Roberto Buizza , Jaap Roger Haartsen , Stefan Winter , Michael Polkey , Rita Priori , Nataly Wieberneit , Kiran Hamilton J. Dellimore
发明人： Rafael Wiemker , Joerg Sabczynski , Thomas Koehler , Cornelis Petrus Hendriks , Roberto Buizza , Jaap Roger Haartsen , Stefan Winter , Michael Polkey , Rita Priori , Nataly Wieberneit , Kiran Hamilton J. Dellimore
IPC分类号： A61M16/00 , A61M16/04
摘要： A respiration monitoring device comprises an electronic controller configured to: receive an audio signal that is acoustically coupled with an airway of a patient receiving mechanical ventilation therapy from a mechanical ventilator; map the audio signal to one or more lung disease or injury condition categories; and at least one of: display the mapped one or more lung disease or injury condition categories on a display device; and determine a recommended adjustment to one or more parameters of the mechanical ventilation therapy delivered to the patient based at least on the mapped lung disease or injury condition categories and displaying the recommended adjustment on the display device.

2. 发明申请

US20130236079A1 METHOD AND DEVICE FOR ANALYSING A REGION OF INTEREST IN AN OBJECT USING X-RAYS 有权
标题翻译：用于分析使用X-RAYS的对象中的兴趣区域的方法和装置
公开(公告)号：US20130236079A1
公开(公告)日：2013-09-12
申请号：US13989507
申请日：2011-12-05
申请人： Ingwer-Curt Carlsen , Thomas Koehler , Gerhard Martens , Ewald Rossl , Rafael Wiemker
发明人： Ingwer-Curt Carlsen , Thomas Koehler , Gerhard Martens , Ewald Rossl , Rafael Wiemker
IPC分类号： G06T7/00
CPC分类号： G06T7/0012 , G01N23/046 , G01N2223/419
摘要： A method and a device for analyzing a region of interest in an object is proposed. The method comprises: (a) providing measurement data by a differential phase contrast X-ray imaging system, and (b) analyzing characteristics of the object in the region of interest. Therein, the measurement data comprise a 2-dimensional or 3-dimensional set of pixels wherein for each pixel the measurement data comprises three types of image data spatially aligned with each other, including (i) absorption representing image data A, (ii) differential phase contrast representing image data D, and (iii) coherence representing image data C. The analyzing step is based, for each pixel, on a combination of at least two of information comprised in the absorption representing image data A and information comprised in the differential phase contrast representing image data D and information comprised in the coherence representing image data C.
摘要翻译：提出了一种用于分析对象中的感兴趣区域的方法和装置。该方法包括：（a）通过差分相位X射线成像系统提供测量数据，以及（b）分析感兴趣区域中物体的特征。其中，测量数据包括2维或3维像素集合，其中对于每个像素，测量数据包括彼此空间对准的三种类型的图像数据，包括（i）表示图像数据A的吸收，（ii）差分表示图像数据D的相位对比度和（iii）表示图像数据C的相干性。分析步骤基于每个像素，包括在表示图像数据A的吸收中包括的信息中的至少两个信息和差分中包含的信息表示图像数据D的相位对比度和表示图像数据C的相干性中包含的信息。

3. 发明申请

US20110150176A1 IMAGE PROCESSING WITH COMPUTER AIDED DETECTION AND/OR DIAGNOSIS 审中-公开
标题翻译：具有计算机辅助检测和/或诊断的图像处理
公开(公告)号：US20110150176A1
公开(公告)日：2011-06-23
申请号：US12675809
申请日：2008-09-05
申请人： Thomas Koehler , Rafael Wiemker
发明人： Thomas Koehler , Rafael Wiemker
IPC分类号： A61B6/03 , G06T7/00
CPC分类号： G06T7/0012 , G06T11/008 , G06T2207/10072 , G06T2207/30064
摘要： The invention relates to a method and an image processing device (10) for the evaluation of image raw-data of a body region generated with an imaging device like a CT scanner (30). From the image raw-data, a first image (ICAD) is reconstructed with a reconstruction module (12) according to reconstruction parameters (p) set optimally by a computer aided detection and/or diagnosis (CAD) module (13). This module can then evaluate an image (ICAD) that was reconstructed optimally according to its own requirements, for example with respect to image size and/or resolution, to find features of interest.
摘要翻译：本发明涉及一种用于评估由诸如CT扫描仪（30）的成像装置生成的身体区域的图像原始数据的方法和图像处理装置（10）。根据图像原始数据，根据由计算机辅助检测和/或诊断（CAD）模块（13）最佳设置的重建参数（p），利用重建模块（12）重建第一图像（ICAD）。然后，该模块可以根据其自己的要求（例如关于图像尺寸和/或分辨率）评估被最优化地重建的图像（ICAD），以找到感兴趣的特征。

4. 发明授权

US09767550B2 Method and device for analysing a region of interest in an object using x-rays 有权
公开(公告)号：US09767550B2
公开(公告)日：2017-09-19
申请号：US13989507
申请日：2011-12-05
申请人： Ingwer-Curt Carlsen , Thomas Koehler , Gerhard Martens , Ewald Rossl , Rafael Wiemker
发明人： Ingwer-Curt Carlsen , Thomas Koehler , Gerhard Martens , Ewald Rossl , Rafael Wiemker
IPC分类号： G06K9/00 , G06T7/00 , G01N23/04
CPC分类号： G06T7/0012 , G01N23/046 , G01N2223/419
摘要： A method and a device for analyzing a region of interest in an object is proposed. The method comprises: (a) providing measurement data by a differential phase contrast X-ray imaging system, and (b) analyzing characteristics of the object in the region of interest. Therein, the measurement data comprise a 2-dimensional or 3-dimensional set of pixels wherein for each pixel the measurement data comprises three types of image data spatially aligned with each other, including (i) absorption representing image data A, (ii) differential phase contrast representing image data D, and (iii) coherence representing image data C. The analyzing step is based, for each pixel, on a combination of at least two of information comprised in the absorption representing image data A and information comprised in the differential phase contrast representing image data D and information comprised in the coherence representing image data C.

5. 发明申请

US20100278409A1 HARDWARE TUMOR PHANTOM FOR IMPROVED COMPUTER-AIDED DIAGNOSIS 审中-公开
标题翻译：硬件肿瘤细胞改进计算机辅助诊断
公开(公告)号：US20100278409A1
公开(公告)日：2010-11-04
申请号：US12746552
申请日：2008-12-12
申请人： Rafael Wiemker , Udo Van Stevendaal , Thomas Koehler , Michael Grass
发明人： Rafael Wiemker , Udo Van Stevendaal , Thomas Koehler , Michael Grass
IPC分类号： G06K9/00
CPC分类号： G06T7/0012 , A61B6/03 , A61B6/583 , G06T7/41 , G06T2207/10081 , G06T2207/10088 , G06T2207/10104 , G06T2207/20104 , G06T2207/30096 , G09B23/30
摘要： An imaging system (1) includes at least one hardware phantom (52, 54, 56, 58) which includes structural features (s, 82, 92) that mimic different structural features of tumors. A scanner (10) acquires image data for a subject (14) in a region of interest (40) and the at least one hardware phantom. A reconstruction processor (32) processes the image data to generate reconstructed image data representative of the region of interest and of the hardware phantom.
摘要翻译：成像系统（1）包括至少一个硬件体模（52,54,56,58），其包括模拟肿瘤的不同结构特征的结构特征（s，82,92）。扫描器（10）获取感兴趣区域（40）中的对象（14）的图像数据和至少一个硬件体模。重建处理器（32）处理图像数据以产生表示感兴趣区域和硬件体模的重建图像数据。

6. 发明授权

US09483844B2 Interactive image analysis 有权
标题翻译：交互式图像分析
公开(公告)号：US09483844B2
公开(公告)日：2016-11-01
申请号：US13806301
申请日：2011-06-28
申请人： Rafael Wiemker , Thomas Buelow , Sebastian Peter Michael Dries
发明人： Rafael Wiemker , Thomas Buelow , Sebastian Peter Michael Dries
IPC分类号： G06T7/60 , G06F19/00
CPC分类号： G06T7/60 , G06F19/00 , G06F19/321
摘要： An interactive image analysis system includes an image visualization subsystem (1) for visualizing an image (8). An indicated position determiner (2) is arranged for determining an indicated position of a pointing device with respect to the image(8). A result determiner (3) is arranged for determining a result of a local image processing of the image (8) at the indicated position. A display subsystem (4) displays either at least part of the result of the local image processing (406) or a visible mark (407), based on the image processing result. The result of the local image processing is indicative of the presence or absence of an object (403) at or near the indicated position (404, 405), and the display subsystem (4) is arranged for displaying the visible mark (407) in the absence of such an object (403) at or near the indicated position (405).
摘要翻译：交互式图像分析系统包括用于可视化图像（8）的图像可视化子系统（1）。指示位置确定器（2）被布置用于确定指示设备相对于图像（8）的指示位置。结果确定器（3）被布置用于确定在所指示的位置处的图像（8）的局部图像处理的结果。显示子系统（4）基于图像处理结果显示局部图像处理（406）的结果的至少一部分或可见标记（407）。本地图像处理的结果表示在指示位置（404,405）处或附近存在或不存在对象（403），并且显示子系统（4）被布置用于将显示标记（407）显示在在指示位置（405）处或附近没有这样的物体（403）。

7. 发明授权

US09261441B2 Generating a slicing scheme for slicing a specimen 有权
标题翻译：生成用于切片的切片方案
公开(公告)号：US09261441B2
公开(公告)日：2016-02-16
申请号：US14116430
申请日：2012-05-08
申请人： Kirsten Meetz , Martin Bergtholdt , Thomas Buelow , Ingwer-Curt Carlsen , Rafael Wiemker
发明人： Kirsten Meetz , Martin Bergtholdt , Thomas Buelow , Ingwer-Curt Carlsen , Rafael Wiemker
IPC分类号： G06K9/00 , C12M1/00 , G01N1/31 , G01N1/06 , G06T7/00 , A61B10/00 , G01N1/28
CPC分类号： G01N1/31 , A61B10/0041 , G01N1/06 , G01N2001/2873 , G06T7/0012
摘要： A system for generating a slicing scheme for slicing a specimen is disclosed. A parameter unit (1) is arranged for determining at least one parameter of a lesion in a specimen, based on an image dataset (14) representing at least part of the specimen. A slicing scheme unit (2) is arranged for determining a slicing scheme (15) for pathologic examination of the specimen, based on the at least one parameter. A specimen preparation unit (3) is arranged for determining a slicing preparation protocol, based on the image dataset, wherein the slicing preparation protocol comprises a representation of preparation steps relating to the specimen. A segmentation unit (5) is arranged for segmenting the lesion in the image dataset (14), wherein the parameter unit (1) is arranged for determining the at least one parameter, based on the segmented lesion.
摘要翻译：公开了一种用于产生用于切片试样的切片方案的系统。基于表示至少部分样本的图像数据集（14），配置参数单元（1），用于确定样本中病变的至少一个参数。基于所述至少一个参数，设置切片方案单元（2），用于确定用于所述样本的病理检查的切片方案（15）。一种样本制备单元（3），用于基于图像数据集来确定切片制备方案，其中切片制备方案包括与试样有关的准备步骤的表示。分割单元（5）被布置用于分割图像数据集（14）中的病变，其中参数单元（1）被布置用于基于分割的病变确定至少一个参数。

8. 发明授权

US09129360B2 Visualization apparatus for visualizing an image data set 有权
标题翻译：用于可视化图像数据集的可视化装置
公开(公告)号：US09129360B2
公开(公告)日：2015-09-08
申请号：US13376213
申请日：2010-06-02
申请人： Rafael Wiemker , Thomas Buelow , Cristian Lorenz , Torbjorn Vik , Sven Kabus
发明人： Rafael Wiemker , Thomas Buelow , Cristian Lorenz , Torbjorn Vik , Sven Kabus
IPC分类号： G09G5/02 , G06T7/00 , G06T11/00 , G06T19/00
CPC分类号： G06T7/0012 , G06T11/001 , G06T19/00 , G06T2200/24 , G06T2207/10081 , G06T2207/10088 , G06T2207/10132 , G06T2207/20021 , G06T2207/20092 , G06T2207/30064 , G06T2210/41 , G06T2219/028 , G06T2219/2012
摘要： The invention relates to a visualization apparatus (1) for visualizing an image data set. The visualization apparatus (1) comprises an image data set providing unit (2) for providing the image data set, a differential property determination unit (5) for determining local differential properties for different regions of the image data set, an assigning unit (6) for assigning visualization properties to the different regions of the image data set depending on the determined local differential properties, wherein a visualization property defines the visualization of a region, to which the visualization property is assigned, and a display unit (7) for displaying the visualization properties assigned to the different regions of the image data set. By displaying the visualization properties assigned to the different regions of the image data set different objects can visually be separated from each other without requiring large computational costs.
摘要翻译：本发明涉及一种用于可视化图像数据集的可视化装置（1）。可视化装置（1）包括用于提供图像数据组的图像数据集提供单元（2），用于确定图像数据组的不同区域的局部差分属性的差分特性确定单元（5），分配单元），用于根据所确定的本地差分属性将可视化属性分配给图像数据集的不同区域，其中可视化属性定义可分配可视化属性的区域的可视化，以及用于显示的显示单元（7）分配给图像数据集的不同区域的可视化属性。通过显示分配给图像数据集的不同区域的可视化属性，不同的对象可以在视觉上彼此分离，而不需要大的计算成本。

9. 发明授权

US08787634B2 Apparatus and method for indicating likely computer-detected false positives in medical imaging data 有权
标题翻译：用于在医学成像数据中指示可能的计算机检测到的假阳性的装置和方法
公开(公告)号：US08787634B2
公开(公告)日：2014-07-22
申请号：US12519799
申请日：2007-12-14
申请人： Rafael Wiemker , Roland Opfer , Thomas Buelow
发明人： Rafael Wiemker , Roland Opfer , Thomas Buelow
IPC分类号： G06K9/00 , G06K9/36 , G06K9/46
CPC分类号： G06T7/0012 , G06T2207/30061
摘要： A data structure for use by a computer system for processing medical image data and representing at least one first region of a patient includes at least one computer-detected feature of interest. The data structure includes a first computer code that is executable to detect first data representing at least one second region included within a respective first region. At least one said feature of interest in said second region has a significant likelihood of representing a computer-detected false positive. The second computer code is executable to provide second data for enabling at least one said first region to be displayed on a display device, such that at least one said second region is displayed on the display apparatus differently from part of said first region not containing features of interest having a significant likelihood of representing computer-detected false positives.
摘要翻译：由计算机系统用于处理医学图像数据并且表示患者的至少一个第一区域的数据结构包括至少一个计算机检测到的感兴趣特征。数据结构包括第一计算机代码，其可执行以检测表示包括在相应的第一区域内的至少一个第二区域的第一数据。所述第二区域中至少一个所述感兴趣的特征具有表示计算机检测到的假阳性的显着可能性。第二计算机代码可执行以提供第二数据，用于使至少一个所述第一区域能够显示在显示设备上，使得至少一个所述第二区域不显示在所述显示设备上，不同于所述第一区域的不包含特征具有代表计算机检测到的误报的显着可能性。

10. 发明授权

US08699768B2 Scan plan field of view adjustor, determiner, and/or quality assessor 有权
公开(公告)号：US08699768B2
公开(公告)日：2014-04-15
申请号：US13508370
申请日：2010-10-14
申请人： Torbjorn Vik , Jorg Bredno , Rafael Wiemker , Mark E. Olszewski
发明人： Torbjorn Vik , Jorg Bredno , Rafael Wiemker , Mark E. Olszewski
IPC分类号： G06K9/00 , A61B6/00
CPC分类号： G06T7/0012 , A61B5/0037 , A61B5/055 , A61B5/7207 , A61B6/032 , A61B6/12 , A61B6/488 , A61B6/5264 , G06T7/32 , G06T7/344 , G06T2207/10081 , G06T2207/30004
摘要： A method includes using a pre-scan image to define a scan field of view for a region of interest of a patient to be scanned for at least one image acquisition of a series of image acquisitions of a scan plan, performing an image acquisition of the series based on a corresponding scan field of view for the image acquisition, and determining, via a processor (120), a next field of view for a next image acquisition of the series based on available image related data.

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