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1. 发明申请

US20180317828A1 ANALYTE MONITORING SYSTEMS AND METHODS 审中-公开
公开(公告)号：US20180317828A1
公开(公告)日：2018-11-08
申请号：US15909572
申请日：2018-03-01
申请人： OptiScan Biomedical Corporation
发明人： James R. Braig , Peter Rule , Philip C. Hartstein , Bernhard B. Sterling , Jennifer H. Gable , Kenneth I. Li
IPC分类号： A61B5/157 , G01N21/35 , A61B5/15 , A61B5/1455 , G01N21/03 , G01N33/66 , G01N33/49 , A61B5/01 , A61B10/00 , A61B5/00 , A61B5/151 , G01N21/3577 , A61B5/145 , G01N21/3581
CPC分类号： A61B5/157 , A61B5/01 , A61B5/1411 , A61B5/14532 , A61B5/1455 , A61B5/150022 , A61B5/150083 , A61B5/150213 , A61B5/150358 , A61B5/150412 , A61B5/150458 , A61B5/150503 , A61B5/150618 , A61B5/150717 , A61B5/15087 , A61B5/151 , A61B5/15107 , A61B5/15136 , A61B5/1514 , A61B5/15194 , A61B5/6826 , A61B5/6838 , A61B10/0045 , A61B2562/0295 , A61B2562/12 , G01N21/03 , G01N21/0332 , G01N21/35 , G01N21/3577 , G01N21/3581 , G01N33/49 , G01N33/66 , G01N2021/0389 , G01N2201/02 , G01N2201/068
摘要： A reagentless whole-blood analyte detection system that is capable of being deployed near a patient has a source capable of emitting a beam of radiation that includes a spectral band. The whole-blood system also has a detector in an optical path of the beam. The whole-blood system also has a housing that is configured to house the source and the detector. The whole-blood system also has a sample element that is situated in the optical path of the beam. The sample element has a sample cell and a sample cell wall that does not eliminate transmittance of the beam of radiation in the spectral band.

2. 发明申请

US20180231533A1 Systems and Methods of Sample Processing and Fluid Control in a Fluidic System 审中-公开
公开(公告)号：US20180231533A1
公开(公告)日：2018-08-16
申请号：US15951641
申请日：2018-04-12
申请人： Theranos IP Company, LLC
发明人： Elizabeth A. HOLMES , Shaunak Roy , Ian Gibbons , Shize Daniel Qi , Edmond Ku , Chris Todd , Melissa Takahashi , Bruce Johnson , Jeff Fenton , Keith Moravick , Uwe Springborn , Anthony Delacruz
IPC分类号： G01N33/53 , A61B5/15 , G01N33/536 , A61B5/00 , A61B5/1486 , G01N33/573 , A61B5/157 , A61B5/151
CPC分类号： G01N33/5302 , A61B5/1411 , A61B5/1486 , A61B5/150022 , A61B5/150213 , A61B5/150221 , A61B5/150229 , A61B5/150251 , A61B5/150274 , A61B5/150282 , A61B5/150412 , A61B5/150503 , A61B5/150755 , A61B5/150778 , A61B5/150786 , A61B5/150854 , A61B5/150862 , A61B5/15087 , A61B5/150969 , A61B5/150984 , A61B5/15142 , A61B5/157 , A61B5/412 , A61B5/685 , G01N33/536 , G01N33/573 , G01N2333/46 , G01N2333/91188 , G01N2800/52
摘要： This invention is in the field of medical devices. Specifically, the present invention provides portable medical devices that allow real-time detection of analytes from a biological fluid. The methods and devices are particularly useful for providing point-of-care testing for a variety of medical applications.

3. 发明授权

US10010280B2 Medical device inserters and processes of inserting and using medical devices 有权
公开(公告)号：US10010280B2
公开(公告)日：2018-07-03
申请号：US13436768
申请日：2012-03-30
申请人： Manuel Luis Donnay , Tuan Nguyen , Louis G. Pace , Peter G. Robinson
发明人： Manuel Luis Donnay , Tuan Nguyen , Louis G. Pace , Peter G. Robinson
IPC分类号： A61B5/157 , A61B5/15 , A61B5/145 , A61M5/158 , A61B5/151 , A61B17/34 , A61B5/00 , A61B5/01
CPC分类号： A61B5/150022 , A61B5/0002 , A61B5/01 , A61B5/1411 , A61B5/14503 , A61B5/14532 , A61B5/14542 , A61B5/14546 , A61B5/15016 , A61B5/150259 , A61B5/150282 , A61B5/150396 , A61B5/150419 , A61B5/150427 , A61B5/150511 , A61B5/150732 , A61B5/15087 , A61B5/15107 , A61B5/15113 , A61B5/15117 , A61B5/1513 , A61B5/15186 , A61B5/1519 , A61B5/15194 , A61B5/157 , A61B5/6865 , A61B17/34 , A61M5/158 , A61M2005/1585
摘要： An apparatus for insertion of a medical device in the skin of a subject is provided, as well as methods of inserting medical devices. Embodiments include removing a substantially cylindrical cap from an inserter to expose a substantially cylindrical sleeve, removing a cover from a substantially cylindrical container holding sensor components, and fitting the sensor components into the inserter.

4. 发明申请

US20180161018A1 FLUID SAMPLING DEVICE 审中-公开
公开(公告)号：US20180161018A1
公开(公告)日：2018-06-14
申请号：US15836998
申请日：2017-12-11
申请人： NEOTERYX, LLC
发明人： Stuart A. KUSHON , Gene ZAMBA , Carolyn JARING , Yibo GUO , David A. NYBERG, II
IPC分类号： A61B10/00 , A61B5/15 , G01N1/10 , G01N1/02
CPC分类号： A61B10/0045 , A61B5/150022 , A61B5/150251 , A61B5/150305 , A61B5/150343 , A61B5/150358 , A61B5/15087 , A61B5/157 , A61B10/0051 , A61B10/007 , A61B2010/0009 , G01N1/02 , G01N1/10 , G01N2001/007 , G01N2001/028
摘要： An absorbent member, and a recorder that identifies a time and a date of fluid absorbed by the absorbent member.

5. 发明申请

US20170340254A1 Real-time blood detection system 审中-公开
公开(公告)号：US20170340254A1
公开(公告)日：2017-11-30
申请号：US15731343
申请日：2017-05-31
申请人： Alice McKinstry Davis , Dennis Willard Davis , Russell Denning Davis
发明人： Alice McKinstry Davis , Dennis Willard Davis , Russell Denning Davis
IPC分类号： A61B5/15 , A61L15/16 , A61B5/00
CPC分类号： A61B5/15087 , A61B5/0022 , A61B5/0024 , A61B5/02042 , A61B5/14532 , A61B5/14546 , A61B5/14556 , A61B5/1477 , A61B5/1486 , A61B5/150015 , A61B5/15003 , A61B5/150045 , A61B5/207 , A61B5/4318 , A61B5/4337 , A61B5/4368 , A61B5/445 , A61B5/6802 , A61B5/7455 , A61B10/0012 , A61B2560/0412 , A61B2562/0285 , A61B2562/125 , A61F13/42 , A61F13/472 , A61F2013/424 , A61L15/16 , H04B1/59 , H04B5/0062
摘要： Disclosed is a system for real-time detection and annunciation of blood associated with menstruation and surgical wounds. The system comprises a real-time, wide area blood detector, communication means for relay of blood detection information, and annunciation means to inform the user of the emanation of blood. Various system embodiments include local and remote as well as covert and non-covert annunciation to users or medical personnel, various forms of real-time blood detection sensors, blood analysis capability, and smart bandage telemetry.

6. 发明申请

US20170311881A1 SYSTEM AND METHOD FOR ADJUSTING THE BLOOD GLUCOSE LEVEL OF A PERSON 审中-公开
公开(公告)号：US20170311881A1
公开(公告)日：2017-11-02
申请号：US15653067
申请日：2017-07-18
申请人： T&W Engineering A/S
发明人： Rasmus Stig JENSEN , Richard TOPHOLM , Erik Skov CHRISTENSEN , Rasmus Elsborg MADSEN
IPC分类号： A61B5/00 , A61B5/145 , A61M5/142 , A61B5/0478 , A61M5/172
CPC分类号： A61B5/4839 , A61B5/0476 , A61B5/0478 , A61B5/14532 , A61B5/150022 , A61B5/15087 , A61B5/150877 , A61B5/155 , A61B5/157 , A61B5/6814 , A61B5/6817 , A61B5/7405 , A61B5/746 , A61M5/142 , A61M5/14244 , A61M5/14276 , A61M5/1723 , A61M2202/0486 , A61M2205/18 , A61M2205/3569 , A61M2205/581 , A61M2230/10 , A61M2230/201
摘要： A system for adjusting blood glucose level including an insulin delivery device configured to release insulin into the body of a person, and an EEG monitor having an EEG sensing part including EEG electrodes. The EEG monitor can be arranged in the ear region of the person with the EEG sensing part arranged subcutaneously at the scalp or arranged in the ear canal. The EEG monitor includes an EEG signal processor arranged at the ear and adapted for identifying onset of hypoglycemia. The system further includes a wireless link between the EEG monitor and the insulin delivery device. The EEG monitor is configured to submit a warning signal to the insulin delivery device if an upcoming onset of hypoglycemia is identified. The warning message will cause the insulin delivery device to restrict insulin delivery for a predetermined time, and a warning is provided to the person or to a caregiver.

7. 发明授权

US09617149B2 Compact fluid analysis device and method to fabricate 有权
公开(公告)号：US09617149B2
公开(公告)日：2017-04-11
申请号：US14567301
申请日：2014-12-11
申请人： IMEC VZW
发明人： Liesbet Lagae , Peter Peumans
IPC分类号： B01L1/00 , B01L3/00 , B81C1/00 , G01N27/414 , A61B5/15 , F15C5/00 , F15C7/00 , G01N27/22 , B01L7/00
CPC分类号： B81C1/00539 , A61B5/1411 , A61B5/150022 , A61B5/150221 , A61B5/150274 , A61B5/150358 , A61B5/15087 , B01L3/502707 , B01L3/502715 , B01L3/50273 , B01L7/52 , B01L2300/046 , B01L2300/0645 , B01L2300/0663 , B01L2300/0681 , B01L2300/0819 , B01L2300/0887 , B01L2300/123 , B01L2300/1833 , B01L2400/0406 , B01L2400/0415 , B01L2400/0688 , B01L2400/086 , B81C1/00238 , F15C5/00 , F15C7/00 , G01N27/227 , G01N27/4148 , Y10T29/494 , Y10T436/143333
摘要： The present disclosure relates to a device for analyzing a fluid sample. In one aspect, the device includes a fluidic substrate that comprises a micro-fluidic component embedded in the fluidic substrate configured to propagate a fluid sample via capillary force through the device and a means for providing a fluid sample connected to the micro-fluidic component. The device also includes a lid attached to the fluidic substrate at least partly covering the fluidic substrate and at least partly closing the micro-fluidic component. The fluidic substrate may be a silicon fluidic substrate and the lid may be a CMOS chip. In another aspect, embodiments of the present disclosure relate to a method for fabricating such a device, and the method may include providing a fluidic substrate, providing a lid, and attaching, through a CMOS compatible bonding process, the fluidic substrate to the lid to close the fluidic substrate at least partly.

8. 发明授权

US09585608B2 Continuous analyte monitor data recording device operable in a blinded mode 有权
标题翻译：连续分析物监测数据记录装置可在盲模式下操作
公开(公告)号：US09585608B2
公开(公告)日：2017-03-07
申请号：US14938712
申请日：2015-11-11
申请人： DexCom, Inc.
发明人： Jorge Valdes , David Price , Leif N. Bowman , Kristin Cote
IPC分类号： A61B5/05 , A61B5/1486 , A61B5/00 , A61B5/15 , A61B5/155 , A61B5/145 , A61B5/151 , A61B5/157 , A61B5/1473 , A61B5/1495
CPC分类号： A61B5/0004 , A61B5/0022 , A61B5/0024 , A61B5/1411 , A61B5/1427 , A61B5/14532 , A61B5/14546 , A61B5/14735 , A61B5/14865 , A61B5/1495 , A61B5/150022 , A61B5/150267 , A61B5/150358 , A61B5/150854 , A61B5/150862 , A61B5/15087 , A61B5/150877 , A61B5/150969 , A61B5/15105 , A61B5/155 , A61B5/157 , A61B5/7282 , A61B5/742 , A61B5/746 , A61B2562/0295 , G06F19/00 , G16H40/67
摘要： A system is provided for monitoring analyte in a host, including a continuous analyte sensor that produces a data stream indicative of a host's analyte concentration and a device that receives and records data from the data stream from the continuous analyte sensor. In one embodiment, the device includes a single point analyte monitor, from which it obtains an analyte value, and is configured to display only single point analyte measurement values, and not any analyte measurement values associated with data received from the continuous analyte sensor. Instead, data received from the continuous analyte sensor is used to provide alarms to the user when the analyte concentration and/or the rate of change of analyte concentration, as measured by the continuous analyte sensor, is above or below a predetermined range. Data received from the continuous analyte sensor may also be used to prompt the diabetic or caregiver to take certain actions, such as to perform another single point blood glucose measurement. In another embodiment, the device provides for toggling between two modes, with one mode that allows for display of glucose concentration values associated with the continuous glucose sensor and a second mode that prevents the display of glucose concentration values associated with the continuous glucose sensor.
摘要翻译：提供了一种用于监测主机中的分析物的系统，包括产生指示宿主分析物浓度的数据流的连续分析物传感器，以及从连续分析物传感器接收并记录来自数据流的数据的设备。在一个实施例中，该装置包括单点分析物监测器，其从其获得分析物值，并且被配置为仅显示单点分析物测量值，而不是与从连续分析物传感器接收的数据相关联的任何分析物测量值。相反，当通过连续分析物传感器测量的分析物浓度和/或分析物浓度的变化速率高于或低于预定范围时，来自连续分析物传感器的数据被用于向用户提供警报。从连续分析物传感器接收的数据也可用于促使糖尿病患者或护理者采取某些措施，例如进行另一单点血糖测量。在另一个实施例中，该装置提供两种模式之间的切换，其中一种模式允许显示与连续葡萄糖传感器相关联的葡萄糖浓度值，以及防止显示与连续葡萄糖传感器相关联的葡萄糖浓度值的第二模式。

9. 发明授权

US09521972B2 Tubular sensor, constituent measuring device, and tubular sensor manufacturing method 有权
标题翻译：管状传感器，构成测量装置和管状传感器制造方法
公开(公告)号：US09521972B2
公开(公告)日：2016-12-20
申请号：US13846524
申请日：2013-03-18
申请人： Terumo Kabushiki Kaisha
发明人： Hideo Kawamoto
IPC分类号： A61B5/05 , A61B5/157 , A61B5/15 , A61B5/1473 , A61B5/153 , A61B5/145 , A61B5/1486 , A61B5/00
CPC分类号： A61B5/157 , A61B5/1411 , A61B5/14532 , A61B5/1473 , A61B5/1486 , A61B5/14865 , A61B5/15003 , A61B5/150282 , A61B5/150389 , A61B5/150396 , A61B5/150511 , A61B5/150847 , A61B5/15087 , A61B5/153 , A61B5/6848 , A61B2562/12 , A61B2562/125 , Y10T29/49002
摘要： A tubular sensor includes a tubular body having a longitudinally extending cavity, an insulation layer formed on the inner wall surface of the tubular body; and a plurality of longitudinally extending electrodes formed on the insulation layer and extending continuously from one end to the other end of the tubular body. The tubular sensor can be employed in a constituent measuring device. The tubular sensor can be manufactured by forming the insulation layer on a thin metal sheet, forming the plurality of electrodes on the insulation layer in stripes, cutting the thin metal sheet with the insulation layer and the electrodes formed thereon to produce a plate-shaped body having a development shape of the tubular body, and press working the plate-shaped body to form the tubular body.
摘要翻译：管状传感器包括具有纵向延伸的空腔的管状体，形成在管状体的内壁表面上的绝缘层; 以及形成在所述绝缘层上并且从所述管状体的一端到另一端连续延伸的多个纵向延伸的电极。管状传感器可用于构成测量装置。可以通过在薄金属片上形成绝缘层来制造管状传感器，在绝缘层上形成多个电极，以绝缘层和形成在其上的电极切割薄金属片，从而产生板状体具有管体的展开形状，并且对板状体进行加压加工以形成管状体。

10. 发明申请

US20160345883A1 TUBULAR SENSOR, CONSTITUENT MEASURING DEVICE, AND TUBULAR SENSOR MANUFACTURING METHOD 审中-公开
标题翻译：管状传感器，构件测量装置和管状传感器制造方法
公开(公告)号：US20160345883A1
公开(公告)日：2016-12-01
申请号：US15236908
申请日：2016-08-15
申请人： Terumo Kabushiki Kaisha
发明人： Hideo KAWAMOTO
IPC分类号： A61B5/157 , A61B5/00 , A61B5/15 , A61B5/153 , A61B5/1486 , A61B5/145
CPC分类号： A61B5/157 , A61B5/1411 , A61B5/14532 , A61B5/1473 , A61B5/1486 , A61B5/14865 , A61B5/15003 , A61B5/150282 , A61B5/150389 , A61B5/150396 , A61B5/150511 , A61B5/150847 , A61B5/15087 , A61B5/153 , A61B5/6848 , A61B2562/12 , A61B2562/125 , Y10T29/49002
摘要： A puncture needle sensor manufacturing method includes applying an insulation layer to a metal sheet and applying spaced apart stripe-shaped electrodes on the insulation layer after the insulation layer is applied on the metal sheet. The manufacturing method also includes cutting the metal sheet to produce a plate-shaped body that includes at least two of the electrodes. The plate-shaped body is press-worked to form the plate-shaped body into a tubular body, and a pointed, beveled end portion is formed at the distal end of the tubular body.
摘要翻译：穿刺针传感器的制造方法包括在将绝缘层涂敷在金属板上之后，在金属板上施加绝缘层，并在绝缘层上施加间隔开的条状电极。制造方法还包括切割金属片以制造包括至少两个电极的板状体。对板状体进行压力加工，将板状体形成管状体，在管状体的前端形成有尖端的倾斜端部。

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