专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

81. 发明授权

US09184039B2 Mass spectrometer with corrugations, wells, or barriers and a driving DC voltage or potential 有权
标题翻译：具有波纹，孔或障碍物和驱动直流电压或电位的质谱仪
公开(公告)号：US09184039B2
公开(公告)日：2015-11-10
申请号：US12092313
申请日：2006-11-01
申请人： Steven Pringle , Jason Lee Wildgoose
发明人： Steven Pringle , Jason Lee Wildgoose
IPC分类号： H01J49/36 , H01J49/06 , H01J49/00 , H01J49/42
CPC分类号： H01J49/062 , H01J49/004 , H01J49/4235 , H01J49/427
摘要： A mass analyzer (2) is provided comprising a plurality of electrodes having apertures through which ions are transmitted in use. A plurality of seudo-potential corrugations are created along the axis of the mass analyzer (2). The amplitude or depth of the pseudo-potential corrugations is inversely proportional to the mass to charge ratio of an ion. One or more transient DC voltages are applied to the electrodes of the mass analyzer (2) in order to urge ions along the length of the mass analyzer (2). The amplitude of the transient DC voltages applied to the electrodes is increased with time and ions are caused to be emitted from the mass analyzer (2) in reverse order of mass to charge ratio.
摘要翻译：提供质量分析器（2），其包括具有孔的多个电极，在使用中通过该孔具有离子。沿着质量分析器（2）的轴线产生多个潜在的波纹。伪电位波纹的振幅或深度与离子的质荷比成反比。为了沿着质量分析器（2）的长度推动离子，一个或多个瞬态直流电压被施加到质量分析器（2）的电极。施加到电极的瞬态直流电压的幅度随着时间而增加，并且使质子分析器（2）以与质荷比相反的顺序发射离子。

82. 发明授权

US09123518B2 Curved ion guide with non mass to charge ratio dependent confinement 有权
标题翻译：具有非质荷比依赖性限制的弯曲离子导向器
公开(公告)号：US09123518B2
公开(公告)日：2015-09-01
申请号：US14001078
申请日：2012-02-24
申请人： Kevin Giles , Martin Raymond Green , Daniel James Kenny , Jason Lee Wildgoose , David. J. Langridge
发明人： Kevin Giles , Martin Raymond Green , Daniel James Kenny , Jason Lee Wildgoose , David. J. Langridge
IPC分类号： H01J49/26 , H01J49/06 , H01J49/42
CPC分类号： H01J49/063 , H01J49/065 , H01J49/26 , H01J49/42
摘要： A non-linear ion guide is disclosed comprising a plurality of electrodes. An ion guiding region is arranged between the electrodes, and the ion guiding region curves at least in a first direction. A DC voltage is applied to at least some of the electrodes in order to form a DC potential well which acts to confine ions within the ion guiding region in the first direction.
摘要翻译：公开了一种包括多个电极的非线性离子导向器。离子引导区域布置在电极之间，并且离子引导区域至少沿第一方向弯曲。 DC电压被施加到至少一些电极，以便形成用于将离子限制在第一方向上的离子引导区域内的DC势阱。

83. 发明授权

US08872104B2 Segmented planar calibration for correction of errors in time of flight mass spectrometers 有权
标题翻译：分段平面校准用于校正飞行时间质谱仪中的误差
公开(公告)号：US08872104B2
公开(公告)日：2014-10-28
申请号：US14117756
申请日：2012-05-16
申请人： David J. Langridge , Jason Lee Wildgoose
发明人： David J. Langridge , Jason Lee Wildgoose
IPC分类号： B01D59/44 , H01J49/00 , H01J49/02
CPC分类号： H01J49/0036 , H01J49/0009 , H01J49/02 , H01J49/025 , H01J49/40 , H01J49/401
摘要： An ion detector system for a mass spectrometer is disclosed comprising an ion detector comprising an array of detector elements. The ion detector system is arranged to correct for tilt and non-linear aberrations in an isochronous plane of ions. The ion detector system generates separate first mass spectral data sets for each detector element and then applies a calibration coefficient to each of the first mass spectral data sets to produce a plurality of second calibrated mass spectral data sets. The plurality of second calibrated mass spectral data sets are then combined to form a composite mass spectral data set.
摘要翻译：公开了一种用于质谱仪的离子检测器系统，其包括具有检测器元件阵列的离子检测器。离子检测器系统被布置成校正离子的等时平面中的倾斜和非线性像差。离子检测器系统为每个检测器元件生成单独的第一质谱数据集，然后将校准系数应用于每个第一质谱数据集以产生多个第二校准质谱数据集。然后将多个第二校准质谱数据组合以形成复合质谱数据集。

84. 发明授权

US08809767B2 Time of flight mass spectrometer with analog to digital converter and method of using 有权
标题翻译：具有模数转换器的飞行时间质谱仪及其使用方法
公开(公告)号：US08809767B2
公开(公告)日：2014-08-19
申请号：US12302168
申请日：2007-06-01
申请人： Robert Harold Bateman , Jeffery Mark Brown , Martin Green , Jason Lee Wildgoose , Anthony James Gilbert , Steven Derek Pringle
发明人： Robert Harold Bateman , Jeffery Mark Brown , Martin Green , Jason Lee Wildgoose , Anthony James Gilbert , Steven Derek Pringle
IPC分类号： H01J49/26 , H01J49/00 , G06K9/00
CPC分类号： H01J49/0036 , G06K9/0053
摘要： A Time of Flight mass analyser is disclosed comprising an ion detector comprising an Analogue to Digital Converter. Output signals from the ion detector are digitised and the arrival times and intensity values relating to ion arrival events are determined. If the determined arrival times from two signals fall within the same time window then the arrival times are added together in a weighted manner and the intensity values are combined.
摘要翻译：公开了一种飞行时间质量分析仪，其包括离子检测器，该离子检测器包括模数转换器。来自离子检测器的输出信号被数字化，确定与离子到达事件有关的到达时间和强度值。如果从两个信号确定的到达时间落在相同的时间窗口内，则以加权的方式将到达时间相加在一起并且强度值被组合。

85. 发明授权

US08633435B2 Mass spectrometer 有权
标题翻译：质谱仪
公开(公告)号：US08633435B2
公开(公告)日：2014-01-21
申请号：US12445774
申请日：2007-10-16
申请人： Daniel James Kenny , Robert Harold Bateman , Martin Green , Jason Lee Wildgoose , Steven Derek Pringle
发明人： Daniel James Kenny , Robert Harold Bateman , Martin Green , Jason Lee Wildgoose , Steven Derek Pringle
IPC分类号： H01J49/42 , H01J49/00 , H01J49/06
CPC分类号： H01J49/005 , H01J49/0031 , H01J49/004 , H01J49/0045 , H01J49/065 , H01J49/34 , H01J49/4235
摘要： A collision or fragmentation cell is disclosed comprising a plurality of electrodes wherein a first RF voltage is applied to an upstream group of electrodes and a second different RF voltage is applied to a downstream group of electrodes. The radial confinement of parent ions entering the collision or fragmentation cell is optimized by the first RF voltage applied to the upstream group of electrodes and the radial confinement of daughter or fragment ions produced within the collision or fragmentation cell is optimized by the second different RF voltage applied to the downstream group of electrodes.
摘要翻译：公开了包括多个电极的碰撞或分裂单元，其中将第一RF电压施加到上游电极组，并且将第二不同的RF电压施加到下游电极组。通过施加到上游电极组的第一RF电压来优化进入碰撞或破碎电池的母体离子的径向约束，并且通过第二不同RF电压优化在碰撞或断裂电池内产生的子或碎片离子的径向约束应用于下游电极组。

86. 发明授权

US08481921B2 Tandem ion trapping arrangement 有权
标题翻译：串联离子捕集装置
公开(公告)号：US08481921B2
公开(公告)日：2013-07-09
申请号：US12676154
申请日：2008-09-03
申请人： Martin Raymond Green , Jason Lee Wildgoose
发明人： Martin Raymond Green , Jason Lee Wildgoose
IPC分类号： B01D59/44 , H01J49/00
CPC分类号： H01J49/06 , H01J49/0031 , H01J49/004 , H01J49/025 , H01J49/26 , H01J49/4265 , H01J49/427
摘要： A mass spectrometer is disclosed comprising a first storage ion trap arranged upstream of a high performance analytical ion trap. According to an embodiment ions are simultaneously scanned from both the first and second ion trap. At any instant in time the quantity of charge present within the second ion trap is limited or restricted so that the second ion trap does not suffer from space charge saturation effects and hence the performance of the second ion trap is not degraded.
摘要翻译：公开了一种质谱仪，其包括布置在高性能分析离子阱的上游的第一存储离子阱。根据一个实施例，离子同时从第一和第二离子阱两者扫描。在任何时刻，存在于第二离子阱内的电荷量被限制或限制，使得第二离子阱不会受到空间电荷饱和效应的影响，因此第二离子阱的性能不会降低。

87. 发明授权

US08455819B2 Mass spectrometer device and method using scanned phase applied potentials in ion guidance 有权
标题翻译：离子引导中使用扫描相应用电位的质谱仪装置和方法
公开(公告)号：US08455819B2
公开(公告)日：2013-06-04
申请号：US13078198
申请日：2011-04-01
申请人： Martin Green , Jason Lee Wildgoose , Steven D. Pringle , Daniel James Kenny
发明人： Martin Green , Jason Lee Wildgoose , Steven D. Pringle , Daniel James Kenny
IPC分类号： H01J49/42 , H01J49/00
CPC分类号： H01J49/065 , H01J49/0031 , H01J49/022 , H01J49/062 , H01J49/36 , H01J49/4235 , Y10T436/24
摘要： An ion guide or mass analyser is disclosed comprising a plurality of electrodes having apertures through which ions are transmitted in use. A pseudo-potential barrier is created at the exit of the ion guide or mass analyser. The amplitude or depth of the pseudo-potential barrier is inversely proportional to the mass to charge ratio of an ion. One or more transient DC voltages are applied to the electrodes of the ion guide or mass analyser in order to urge ions along the length of the ion guides or mass analyser. The amplitude of the transient DC voltage applied to the electrode may be increased with time so that ions are caused to be emitted from the ion guide or mass analyser in reverse order of their mass to charge ratio.
摘要翻译：公开了一种离子导向器或质量分析器，其包括具有孔的多个电极，在使用中离子传播通过该孔。在离子导向器或质量分析器的出口处产生伪势垒。伪势垒的幅度或深度与离子的质荷比成反比。一个或多个瞬态直流电压被施加到离子导向器或质量分析器的电极，以沿着离子导向器或质量分析器的长度推动离子。施加到电极的瞬态直流电压的幅度可以随时间增加，使得离子从离子导向器或质量分析器以其质荷比的相反顺序被发射。

88. 发明授权

US08410430B2 Mass spectrometer 有权
标题翻译：质谱仪
公开(公告)号：US08410430B2
公开(公告)日：2013-04-02
申请号：US12522769
申请日：2008-01-15
申请人： Daniel James Kenny , Jason Lee Wildgoose
发明人： Daniel James Kenny , Jason Lee Wildgoose
IPC分类号： H01J49/00
CPC分类号： H01J49/401
摘要： A Time of Flight mass analyser is disclosed wherein the time period between successive orthogonal acceleration pulses is less than the time of flight of ions having the maximum mass to charge ratio of interest. As a result, some ions are subject to wrap-around and will appear in a subsequent mass spectrum. Mass spectra obtained at two different sampling rates may be compared and mass peaks relating to ions which have and have not been subject to wrap-around may be identified.
摘要翻译：公开了一种飞行时间质量分析器，其中连续正交加速脉冲之间的时间段小于具有最大质荷比的离子的飞行时间。结果，一些离子被卷绕并将出现在随后的质谱中。可以比较以两种不同采样速率获得的质谱，并且可以鉴定与具有和未被卷绕的离子相关的质谱峰。

89. 发明申请

US20120208289A1 Mass Spectrometer 有权
标题翻译：质谱仪
公开(公告)号：US20120208289A1
公开(公告)日：2012-08-16
申请号：US13453657
申请日：2012-04-23
申请人： Martin R. Green , Jason Lee Wildgoose , Jeffery Mark Brown
发明人： Martin R. Green , Jason Lee Wildgoose , Jeffery Mark Brown
IPC分类号： G01N27/62
CPC分类号： H01J49/0481 , H01J49/0072 , H01J49/065 , H01J49/40 , Y10T436/24
摘要： A mass spectrometer is disclosed comprising an Electron Transfer Dissociation cell. Positive analyte ions are fragmented into fragment ions upon colliding with singly charged negative reagent ions with the cell. The cell comprises a plurality of ring electrodes which form a spherical trapping volume. Ions experience negligible RF heating over the majority of the trapping volume which enables the kinetic energy of the analyte and reagent ions to be reduced to just above thermal temperatures. An Electron Transfer Dissociation cell having an enhanced sensitivity is thereby provided. Fragment ions created within the cell may be cooled and may be transmitted onwardly to an orthogonal acceleration Time of Flight mass analyser enabling a significant improvement in the resolution of the mass analyser to be obtained.
摘要翻译：公开了一种质谱仪，其包括电子转移解离单元。当与单体电荷的负试剂离子碰撞时，阳性分析物离子被碎裂成碎片离子。电池包括形成球形捕获体积的多个环形电极。在大多数捕集体积下，离子经历可忽略的RF加热，使得分析物和试剂离子的动能能够降低到高于热温度。从而提供具有增强的灵敏度的电子转移解离电池。在细胞内产生的片段离子可以被冷却并且可以向内传播到正交加速时间飞行质量分析仪，使得可以获得质量分析仪的分辨率的显着提高。

90. 发明授权

US08183524B2 Mass spectrometer having time of flight mass analyser 有权
标题翻译：质谱仪具有飞行时间质量分析仪
公开(公告)号：US08183524B2
公开(公告)日：2012-05-22
申请号：US12516610
申请日：2007-12-14
申请人： Daniel James Kenny , Jason Lee Wildgoose , Martin Green
发明人： Daniel James Kenny , Jason Lee Wildgoose , Martin Green
IPC分类号： H01J49/00
CPC分类号： H01J49/401
摘要： A mass spectrometer is disclosed comprising an orthogonal acceleration Time of Flight mass analyser. A pulse or packet of ions is released either from an ion trap or alternatively from a travelling wave ion guide arranged upstream of an orthogonal acceleration electrode which forms part of the Time of Flight mass analyser. Ions in the pulse or packet or ions which is released become temporally dispersed and the orthogonal acceleration electrode is energized multiple times prior the release of a subsequent pulse or packet of ions.
摘要翻译：公开了一种质谱仪，其包括正交加速时间飞行质量分析器。离子的脉冲或分组从离子阱或者替代地布置在构成飞行时间质量分析器的一部分的正交加速电极的上游的行波离子导向器释放。释放的脉冲或包或离子中的离子变得暂时分散，并且在随后的脉冲或包离子的释放之前，正交加速电极被多次通电。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式