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1. 发明授权

US09123518B2 Curved ion guide with non mass to charge ratio dependent confinement 有权
标题翻译：具有非质荷比依赖性限制的弯曲离子导向器
公开(公告)号：US09123518B2
公开(公告)日：2015-09-01
申请号：US14001078
申请日：2012-02-24
申请人： Kevin Giles , Martin Raymond Green , Daniel James Kenny , Jason Lee Wildgoose , David. J. Langridge
发明人： Kevin Giles , Martin Raymond Green , Daniel James Kenny , Jason Lee Wildgoose , David. J. Langridge
IPC分类号： H01J49/26 , H01J49/06 , H01J49/42
CPC分类号： H01J49/063 , H01J49/065 , H01J49/26 , H01J49/42
摘要： A non-linear ion guide is disclosed comprising a plurality of electrodes. An ion guiding region is arranged between the electrodes, and the ion guiding region curves at least in a first direction. A DC voltage is applied to at least some of the electrodes in order to form a DC potential well which acts to confine ions within the ion guiding region in the first direction.
摘要翻译：公开了一种包括多个电极的非线性离子导向器。离子引导区域布置在电极之间，并且离子引导区域至少沿第一方向弯曲。 DC电压被施加到至少一些电极，以便形成用于将离子限制在第一方向上的离子引导区域内的DC势阱。

2. 发明授权

US08872104B2 Segmented planar calibration for correction of errors in time of flight mass spectrometers 有权
标题翻译：分段平面校准用于校正飞行时间质谱仪中的误差
公开(公告)号：US08872104B2
公开(公告)日：2014-10-28
申请号：US14117756
申请日：2012-05-16
申请人： David J. Langridge , Jason Lee Wildgoose
发明人： David J. Langridge , Jason Lee Wildgoose
IPC分类号： B01D59/44 , H01J49/00 , H01J49/02
CPC分类号： H01J49/0036 , H01J49/0009 , H01J49/02 , H01J49/025 , H01J49/40 , H01J49/401
摘要： An ion detector system for a mass spectrometer is disclosed comprising an ion detector comprising an array of detector elements. The ion detector system is arranged to correct for tilt and non-linear aberrations in an isochronous plane of ions. The ion detector system generates separate first mass spectral data sets for each detector element and then applies a calibration coefficient to each of the first mass spectral data sets to produce a plurality of second calibrated mass spectral data sets. The plurality of second calibrated mass spectral data sets are then combined to form a composite mass spectral data set.
摘要翻译：公开了一种用于质谱仪的离子检测器系统，其包括具有检测器元件阵列的离子检测器。离子检测器系统被布置成校正离子的等时平面中的倾斜和非线性像差。离子检测器系统为每个检测器元件生成单独的第一质谱数据集，然后将校准系数应用于每个第一质谱数据集以产生多个第二校准质谱数据集。然后将多个第二校准质谱数据组合以形成复合质谱数据集。

3. 发明授权

US09425035B2 Ion trap with spatially extended ion trapping region 有权
标题翻译：离子阱具有空间延伸的离子捕获区域
公开(公告)号：US09425035B2
公开(公告)日：2016-08-23
申请号：US14240586
申请日：2012-08-22
申请人： Kevin Giles , Martin Raymond Green , Daniel James Kenny , David J. Langridge , Jason Lee Wildgoose
发明人： Kevin Giles , Martin Raymond Green , Daniel James Kenny , David J. Langridge , Jason Lee Wildgoose
IPC分类号： H01J49/00 , H01J49/42 , H01J49/40
CPC分类号： H01J49/4285 , H01J49/0031 , H01J49/062 , H01J49/063 , H01J49/40 , H01J49/422
摘要： A mass or mass to charge ratio selective ion trap is disclosed which directs ions into a small ejection region. A RF voltage acts to confine ions in a first (y) direction within the ion trap. A DC or RF voltage acts to confine ions in a second (x) direction. A quadratic DC potential well acts to confine ions in a third (z) direction within the ion trap. The profile of the quadratic DC potential well progressively varies along the second (x) direction.
摘要翻译：公开了将离子引导到小的喷射区域中的质量或质量比的选择性离子阱。 RF电压用于将离子限制在离子阱内的第一（y）方向。 DC或RF电压用于将离子限制在第二（x）方向。二次直流势阱用于将离子限制在离子阱内的第三（z）方向。二次直流电势的曲线沿着第二（x）方向逐渐变化。

4. 发明授权

US08829433B2 Ion mobility separator with variable effective length 有权
标题翻译：具有可变有效长度的离子迁移分离器
公开(公告)号：US08829433B2
公开(公告)日：2014-09-09
申请号：US14004486
申请日：2012-03-13
申请人： Martin Raymond Green , David J. Langridge , Jason Lee Wildgoose
发明人： Martin Raymond Green , David J. Langridge , Jason Lee Wildgoose
IPC分类号： B01D59/44 , H01J49/36
CPC分类号： H01J49/36 , G01N27/624 , H01J49/06 , H01J49/42 , H01J49/426
摘要： An ion mobility separator or spectrometer is disclosed comprising an inner cylinder and an outer cylinder defining an annular volume through which ions are transmitted. Spiral electrodes a-f are arranged on a surface of the inner cylinder and/or on a surface of the outer cylinder. A first device is arranged and adapted to maintain a DC electric field or a pseudo-potential force which acts to urge ions from a first end of the ion mobility separator or spectrometer to a second end of the ion mobility separator or spectrometer. A second device is arranged and adapted to apply one or more transient DC voltages to the spiral electrodes in order to urge ions towards the first end of the ion mobility separator or spectrometer. The net effect is to extend the effective path length of the ion mobility separator.
摘要翻译：公开了一种离子迁移率分离器或光谱仪，其包括限定通过离子传播的环形体积的内圆筒和外圆筒。螺旋电极a-f布置在内筒的表面上和/或外筒的表面上。第一装置被布置并适于维持DC电场或伪电势力，其作用是将离子从离子迁移率分离器或光谱仪的第一端推到离子迁移率分离器或光谱仪的第二端。第二装置被布置并适于将一个或多个瞬态DC电压施加到螺旋电极，以促使离子朝向离子迁移分离器或光谱仪的第一端。净效应是延长离子迁移率分离器的有效路径长度。

5. 发明申请

US20140054454A1 Electrostatic Gimbal for Correction of Errors in Time of Flight Mass Spectrometers 有权
标题翻译：用于校正飞行时间质谱误差的静电万向节
公开(公告)号：US20140054454A1
公开(公告)日：2014-02-27
申请号：US14004946
申请日：2012-03-13
申请人： John Brian Hoyes , David J. Langridge , Jason Wildgoose
发明人： John Brian Hoyes , David J. Langridge , Jason Wildgoose
IPC分类号： H01J49/40
CPC分类号： H01J49/403 , H01J49/40
摘要： A Time of Flight mass analyser is disclosed comprising one or more devices arranged and adapted to correct for tilt in an isochronous plane of ions and to adjust the isochronous plane of the ions so as to be parallel with the plane of detection in an ion detector.
摘要翻译：公开了一种飞行时间质量分析器，其包括一个或多个设备，其被配置并适于校正离子的等时平面中的倾斜，并且在离子检测器中调整离子的等时平面以与检测平面平行。

6. 发明申请

US20150294850A1 Ion Trap With Spatially Extended Ion Trapping Region 有权
标题翻译：离子阱与空间扩展的离子捕获区域
公开(公告)号：US20150294850A1
公开(公告)日：2015-10-15
申请号：US14240586
申请日：2012-08-22
申请人： Kevin Giles , Martin Raymond Green , Daniel James Kenny , David J. Langridge , Jason Lee Wildgoose
发明人： Kevin Giles , Martin Raymond Green , Daniel James Kenny , David J. Langridge , Jason Lee Wildgoose
IPC分类号： H01J49/42 , H01J49/00 , H01J49/40
CPC分类号： H01J49/4285 , H01J49/0031 , H01J49/062 , H01J49/063 , H01J49/40 , H01J49/422
摘要： A mass or mass to charge ratio selective ion trap is disclosed which directs ions into a small ejection region. A RF voltage acts to confine ions in a first (y) direction within the ion trap. A DC or RF voltage acts to confine ions in a second (x) direction. A quadratic DC potential well acts to confine ions in a third (z) direction within the ion trap. The profile of the quadratic DC potential well progressively varies along the second (x) direction.
摘要翻译：公开了将离子引导到小的喷射区域中的质量或质量比的选择性离子阱。 RF电压用于将离子限制在离子阱内的第一（y）方向。 DC或RF电压用于将离子限制在第二（x）方向。二次直流势阱用于将离子限制在离子阱内的第三（z）方向。二次直流电势的曲线沿着第二（x）方向逐渐变化。

7. 发明授权

US08946626B2 Ion trap with spatially extended ion trapping region 有权
标题翻译：离子阱具有空间延伸的离子捕获区域
公开(公告)号：US08946626B2
公开(公告)日：2015-02-03
申请号：US14240667
申请日：2012-08-22
申请人： Kevin Giles , Martin Raymond Green , Daniel James Kenny , David J. Langridge , Jason Lee Wildgoose
发明人： Kevin Giles , Martin Raymond Green , Daniel James Kenny , David J. Langridge , Jason Lee Wildgoose
IPC分类号： H01J49/00 , H01J49/42 , B01D59/44
CPC分类号： H01J49/424 , H01J49/421 , H01J49/422 , H01J49/4285
摘要： A mass or mass to charge ratio selective ion trap is disclosed having an increased charge storage capacity. A RF voltage acts to confine ions in a first (y) direction within the ion trap. A DC voltage and/or an RF voltage acts to confine ions in a second (x) direction within the ion trap. A quadratic DC potential well acts to confine ions in a third (z) direction within the ion trap. Ions are excited in the third (z) direction and are caused to be mass or mass to charge ratio selectively ejected in the third (z) direction.
摘要翻译：公开了具有增加的电荷存储容量的质量或质量 - 电荷比选择性离子阱。 RF电压用于将离子限制在离子阱内的第一（y）方向。 DC电压和/或RF电压用于将离子限制在离子阱内的第二（x）方向。二次直流势阱用于将离子限制在离子阱内的第三（z）方向。离子在第三（z）方向上被激发，并且被导致在第三（z）方向上选择性地喷射的质量或质量 - 充电比。

8. 发明授权

US08895920B2 Mass spectrometer with beam expander 有权
公开(公告)号：US08895920B2
公开(公告)日：2014-11-25
申请号：US13702931
申请日：2011-06-07
申请人： Jeffery Mark Brown , Anthony James Gilbert , John Brian Hoyes , David J. Langridge , Jason Lee Wildgoose
发明人： Jeffery Mark Brown , Anthony James Gilbert , John Brian Hoyes , David J. Langridge , Jason Lee Wildgoose
IPC分类号： H01J49/40 , H01J49/00 , H01J49/06
CPC分类号： H01J49/401 , H01J49/0031 , H01J49/0095 , H01J49/062 , H01J49/067 , H01J49/405
摘要： A mass spectrometer is disclosed comprising a RF confinement device, a beam expander and a Time of Flight mass analyzer. The beam expander is arranged to expand an ion beam emerging from the RF confinement device so that the ion beam is expanded to a diameter of at least 3 mm in the orthogonal acceleration extraction region of the Time of Flight mass analyzer.

9. 发明授权

US08283628B2 Ion mobility spectrometer 有权
标题翻译：离子迁移谱仪
公开(公告)号：US08283628B2
公开(公告)日：2012-10-09
申请号：US13060100
申请日：2009-08-14
申请人： John Brian Hoyes , David J. Langridge
发明人： John Brian Hoyes , David J. Langridge
IPC分类号： B01D59/44
CPC分类号： H01J49/0081 , G01N27/622
摘要： An ion mobility spectrometer is disclosed wherein ions are passed through an ion mobility spectrometer (5) and become temporally separated. Ions having a relatively high ion mobility are transmitted by a non-destructive ion gate (6) but ions having a relatively low ion mobility are subsequently trapped within the ion mobility spectrometer (5) when the ion gate (6) is switched so as to prevent ions from being onwardly transmitted. Ions which are transmitted by the ion gate (6) are trapped in a downstream ion trap (7). The ions are then returned back upstream to a second upstream ion trap (4).
摘要翻译：公开了一种离子迁移谱仪，其中离子通过离子迁移谱仪（5）并在时间上分离。具有较高离子迁移率的离子通过非破坏性离子浇口（6）传输，但当离子浇道（6）被切换时，离子迁移谱仪（5）中随后将具有较低离子迁移率的离子捕获到离子迁移谱仪防止离子向上传播。由离子栅（6）传输的离子被捕获在下游离子阱（7）中。然后离子返回上游到第二上游离子阱（4）。

10. 发明申请

US20110291001A1 Ion Mobility Spectrometer 有权
标题翻译：离子流动光谱仪
公开(公告)号：US20110291001A1
公开(公告)日：2011-12-01
申请号：US13060100
申请日：2009-08-14
申请人： John Brian Hoyes , David J. Langridge
发明人： John Brian Hoyes , David J. Langridge
IPC分类号： H01J49/26
CPC分类号： H01J49/0081 , G01N27/622
摘要： An ion mobility spectrometer is disclosed wherein ions are passed through an ion mobility spectrometer (5) and become temporally separated. Ions having a relatively high ion mobility are transmitted by a non-destructive ion gate (6) but ions having a relatively low ion mobility are subsequently trapped within the ion mobility spectrometer (5) when the ion gate (6) is switched so as to prevent ions from being onwardly transmitted. Ions which are transmitted by the ion gate (6) are trapped in a downstream ion trap (7). The ions are then returned back upstream to a second upstream ion trap (4).
摘要翻译：公开了一种离子迁移谱仪，其中离子通过离子迁移谱仪（5）并在时间上分离。具有较高离子迁移率的离子通过非破坏性离子浇口（6）传输，但当离子浇道（6）被切换时，离子迁移谱仪（5）中随后将具有较低离子迁移率的离子捕获到离子迁移谱仪防止离子向上传播。由离子栅（6）传输的离子被捕获在下游离子阱（7）中。然后离子返回上游到第二上游离子阱（4）。

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