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1. 发明公开

EP2380449A4 UNFERMENTED MALT DRINK WITH BEER FLAVOR HAVING REDUCED OR RELIEVED SOURNESS AND METHOD FOR PRODUCING THE SAME 审中-公开
标题翻译：与减少或啤酒口味不发酵麦芽饮料减毒HERB意识及其制造方法
公开(公告)号：EP2380449A4
公开(公告)日：2014-07-02
申请号：EP09837520
申请日：2009-08-21
申请人： KIRIN BREWERY
发明人： ITAKURA TAKEHITO , OTA TAKEHITO , KITO HIDEAKI
IPC分类号： A23L2/38 , A23L2/56 , A23L2/68 , A23L27/00 , C12C12/04
CPC分类号： A23L2/68 , A23L2/38 , A23L2/56 , A23L27/84 , C12C5/026

2. 发明公开

EP1911677A4 PRODUCTION METHOD OF HERMETICALLY SEALED CONTAINER FOR DRINK OR FOOD 有权
标题翻译：工艺用于密封容器的饮料或航空食品
公开(公告)号：EP1911677A4
公开(公告)日：2012-04-25
申请号：EP06796294
申请日：2006-08-01
申请人： KIRIN BREWERY , HAMAMATSU PHOTONICS KK
发明人： NAKAYA MASAKI , KAN HIROFUMI
IPC分类号： B65B7/28 , B21D51/26 , B23K26/04 , B23K26/067 , B23K26/073 , B23K26/20 , B23K26/32 , B29C65/16 , B29K305/02 , B29K305/12 , B29K309/02 , B29K309/08 , B65B51/10 , B65B51/22
CPC分类号： B65B51/22 , B21D51/2661 , B23K26/0676 , B23K26/206 , B29C65/1616 , B29C65/1635 , B29C65/1667 , B29C65/1677 , B29C65/1683 , B29C65/1687 , B29C65/64 , B29C66/1122 , B29C66/542 , B29C66/65 , B29C66/71 , B29C66/72321 , B29C66/7234 , B29C66/73921 , B29C66/742 , B29C66/7461 , B29C66/7465 , B29C66/8322 , B29C66/843 , B29C66/91216 , B29C66/9131 , B29C66/91641 , B29C66/93431 , B29C66/939 , B29C66/9672 , B29K2023/06 , B29K2023/12 , B29K2025/00 , B29K2027/06 , B29K2027/08 , B29K2027/18 , B29K2033/12 , B29K2055/02 , B29K2059/00 , B29K2067/00 , B29K2067/006 , B29K2069/00 , B29K2077/00 , B29K2081/06 , B29K2096/005 , B29K2305/00 , B29K2305/02 , B29K2305/12 , B29K2309/02 , B29K2309/08 , B29K2995/0027 , B29L2009/003 , B29L2031/7158 , B65B7/2878 , B29C65/00 , B29K2079/085 , B29K2067/003 , B29K2033/20 , B29K2025/08 , B29K2025/06 , B29K2023/38 , B29K2023/18 , B29K2023/086
摘要： An object of the present invention is to provide a method for producing a hermetically sealed container, which method comprises conducting hermetic sealing of a container for beverage or food using a laser welding method, whereby the process speed of the sealing process can be made fast, strict control of the scanning position of laser spots is unnecessary, partial oversupply of energy does not occur easily, and there is no reduction in the welding area or welding strength per area due to the gathering of water drops. The method for producing a hermetically sealed container for beverage or food according to the present invention is characterized in being a method for producing a hermetically sealed container for beverage or food, the method comprising a container body and a lid mounted on the mouth portion of the container body according to a laser welding method to an airtight state, wherein the method comprises a process of welding the entire intended welding site of the container body and the lid simultaneously or almost simultaneously.

3. 发明公开

EP1721831A4 SEALED VESSEL AND METHOD OF PRODUCING THE SAME 审中-公开
标题翻译：锁上的容器内及其制造方法
公开(公告)号：EP1721831A4
公开(公告)日：2010-02-17
申请号：EP05710636
申请日：2005-02-24
申请人： KIRIN BREWERY
发明人： NAKAYA MASAKI , SHIRAKURA AKIRA
IPC分类号： B65D8/02 , B29C65/00 , B29C65/16 , B65B7/28 , B65D1/02 , B65D53/00 , B65D77/20
CPC分类号： B29C66/652 , B29C65/1619 , B29C65/1635 , B29C65/1654 , B29C65/1661 , B29C65/1664 , B29C65/1677 , B29C65/1683 , B29C65/76 , B29C66/112 , B29C66/1122 , B29C66/114 , B29C66/122 , B29C66/131 , B29C66/232 , B29C66/301 , B29C66/53461 , B29C66/542 , B29C66/65 , B29C66/71 , B29C66/72323 , B29C66/72325 , B29C66/72343 , B29C66/73921 , B29C66/8322 , B29C66/836 , B29C66/8432 , B29C66/91216 , B29C66/91221 , B29C66/9131 , B29C66/934 , B29C66/939 , B29K2995/0027 , B29L2031/7158 , B65B7/2878 , B65D77/2024 , B65D2543/00425 , B65D2543/00842 , Y02W30/807 , B29K2023/06 , B29K2023/086 , B29K2023/12 , B29K2023/18 , B29K2023/38 , B29K2025/06 , B29K2025/08 , B29K2027/06 , B29K2027/08 , B29K2027/18 , B29K2033/12 , B29K2033/20 , B29K2055/02 , B29K2059/00 , B29K2067/00 , B29K2067/003 , B29K2067/006 , B29K2069/00 , B29K2077/00 , B29K2081/06 , B29K2096/005
摘要： It is an object of the present invention to provide a container in which it is difficult for liquid to drip at a mouth portion having a good touch sensation by forming a structure in which a welded portion that was laser welded in a sealed container does not form a flange, and to carry out the achievement of making polymer material unnecessary and making excessive material in the wind-fastening portion unnecessary. Further, it is also an object to construct the lid and barrel of the vessel by using the same material, thereby facilitating the recycling of material. The sealed container in which a container body 1 having an opening 9 is sealed by a lid portion 3 which closes and covers said opening, comprising a welded portion 4, 14 in which an outer wall surface of a peripheral portion 2 of said opening or an edge 12 surface of said opening and an inner wall surface of said lid portion are laser welded in order to make it possible for at least an inner wall surface of the peripheral portion of said opening from an inner wall surface 6 of said container body to make contact with container contents.

4. 发明公开

EP1688483A4 METHOD OF PREPARING LANGERHANS CELL FROM CD14-POSITIVE CELL BEING HUMAN PERIPHERAL-BLOOD MONONUCLEAR CELL WITH USE OF NOTCH LIGAND DELTA-1, GM-CSF AND TGF-BETA 审中-公开
标题翻译：用于制造朗格汉斯DELETE从细胞CD14阳性细胞WHEN是人外周血细胞的方法是单核，采用Notch配体DELTA-1，GM-CSF和TGF-β
公开(公告)号：EP1688483A4
公开(公告)日：2007-09-12
申请号：EP04748047
申请日：2004-07-22
申请人： KIRIN BREWERY
发明人： KATAYAMA NAOYUKI , OISHI KOSHI , SHIKU HIROSHI
IPC分类号： A61K35/12 , A61K35/14 , C12N5/0784
CPC分类号： C12N5/0639 , A61K2035/124 , C12N2501/15 , C12N2501/22 , C12N2501/42
摘要： This invention provides a method for preparing Langerhans cells from CD14-positive cells, which are human peripheral blood mononuclear cells. This method comprises culturing human peripheral blood mononuclear cells in the presence of Notch ligand, GM-CSF, and TGF-².

5. 发明公开

EP1634600A4 ANTIALLERGIC COMPOSITION 审中-公开
标题翻译： ANTI过敏性成分
公开(公告)号：EP1634600A4
公开(公告)日：2007-03-14
申请号：EP04715523
申请日：2004-02-27
申请人： KIRIN BREWERY
发明人： INOUE S , FUJII T , FUJIWARA D , SAIKI A , TAKAHASHI M , YAMAUCHI K , GOTO M , NISHIDA S , DEUCHI K , WAKABAYASHI H , YONEDA T
IPC分类号： A23L1/30 , A23L2/52 , A23C9/123 , A23F3/16 , A23F3/34 , A23F5/24 , A23L1/28 , A23L2/02 , A61K35/74 , A61P11/02 , A61P11/06 , A61P17/00 , A61P27/02 , A61P27/14 , A61P27/16 , A61P31/00 , A61P35/00 , A61P37/08 , A61P43/00 , C12N1/20 , C12Q1/02 , C12R1/225
CPC分类号： A23C9/1234 , A23F3/166 , A23F3/34 , A23F5/246 , A23L2/52 , A23L33/135 , A23Y2220/67 , A61K35/747
摘要： It is intended to provide an antiallergic composition which is useful in preventing and treating allergy, a method of preparing the same and utilization thereof as foods, drinks, etc. An allergic composition containing, as the active ingredient, a lactic acid bacterium which shows an interleukin 12 productivity comparable to the case using L. paracasei KW3110 strain as a test lactic acid bacterium or at least 60% as much as the case using L. paracasei KW3110 strain and an interleukin 4 productivity less than 50% of the control case without adding any lactic acid bacteria, when cultured in an egg albumin-containing medium in which mouse spleen-origin lymphocytes having been sensitized with egg albumin are suspended. A method of obtaining the lactic acid bacterium having a high antiallergic activity, which is the active ingredient of the antiallergic composition; utilization of the antiallergic composition in foods, drinks, etc.; and utilization of the antiallergic composition by processing it into an antiallergic preparation for oral administration.

6. 发明公开

EP1264886A4 IMPROVED PROMOTERS AND UTILIZATION THEREOF 有权
标题翻译：改进的发起人及其用途
公开(公告)号：EP1264886A4
公开(公告)日：2006-09-06
申请号：EP01906273
申请日：2001-02-23
申请人： KIRIN BREWERY
发明人： FUJII TOSHIO , OGAWA TOSHIYA , YOSHIOKA MASAHARU , MAMIYA KANJI , TOGURI TOSHIHIRO
IPC分类号： C12N15/67 , C12N15/82 , C12N15/83 , C12N15/11 , A01H5/00 , C12N5/10 , C12P21/02
CPC分类号： C12N15/67 , C12N15/8216
摘要： Promoters having been improved so as not to undergo methylation in the course of constructing transformants. The above promoters are DNAs as defined by the following (1) or (2): (1) DNAs containing the base sequences represented by SEQ ID NOS:1 to 4; and (2) DNAs containing base sequences derived from the base sequences represented by SEQ ID NOS:1 to 4 by deletion, addition or insertion of one to several bases, being free from the consecutive sequences represented by CG, CAG, CTG, CCG and CGG in the deleted, added or inserted base sequence, and having a promoter activity. By using these promoters, the expression efficiency of a structural gene of a plant showing weak expression even by using cauliflower mosaic virus 35S promoter, which has been considered as a high-expression promoter for plants, (for example, chrysanthemum) can be elevated.

7. 发明公开

EP1559782A4 HUMAN ARTIFICIAL CHROMOSOME (HAC) VECTOR 有权
标题翻译： HAC载体（人类人工染色体 - 人工人类染色体）
公开(公告)号：EP1559782A4
公开(公告)日：2006-06-21
申请号：EP03751334
申请日：2003-10-03
申请人： KIRIN BREWERY
发明人： OSHIMURA MITSUO , KATOH MOTONOBU , TOMIZUKA KAZUMA , KUROIWA YOSHIMI , KAKEDA MINORU
IPC分类号： C12N1/15 , C12N1/19 , C12N1/21 , C12N15/85 , C12N15/09 , C12N5/10 , C12P21/02
CPC分类号： C12N15/85 , C12N2800/208 , C12N2800/30
摘要： A human artificial chromosome (HAC) vector and a method of constructing the same; a method of transferring a foreign DNA and a method of constructing cells expressing a foreign DNA by using the human artificial chromosome vector; and a process for producing a protein.

8. 发明公开

EP1652961A1 METHOD OF MANUFACTURING GAS BARRIER FILM COATED PLASTIC CONTAINER 审中-公开
标题翻译： VERFAHREN ZUR HERSTELLUNG EINES MIT EINEM GASBARRIEREFILM BESCHICHTETENKUNSTSTOFFBEHÄLTERS
公开(公告)号：EP1652961A1
公开(公告)日：2006-05-03
申请号：EP04747572.8
申请日：2004-07-15
申请人： MITSUBISHI SHOJI PLASTICS CORPORATION , Youtec Co. Ltd. , Kirin Brewery Company, Ltd.
发明人： TAKEMOTO, Keishu , KAGE, Tsuyoshi , KOBAYASHI, Takumi , SHIRAKURA, Akira
IPC分类号： C23C16/02 , C23C16/509 , B65D23/02
CPC分类号： C23C16/045
摘要： A method of manufacturing a gas barrier film coated plastic container with high gas-barrier properties by solving a problem in a conventional method wherein the formation of a gas barrier film is obstructed by water molecules adsorbed in the plastic container and the container with reduced gas-barrier properties is manufactured. The method is characterized by comprising the steps of decreasing a pressure inside the plastic container or decreasing a pressure to the entire part of the plastic container, flowing dry gas as leak gas when vacuum is released to fill the inside of the container with the dry gas for drying the plastic container, replacing the gas inside the plastic container with a material gas or a material gas-containing gas, and plasmatizing the material gas to form the gas barrier film on the inner surface of the plastic container by a CVD method.
摘要翻译：通过解决常规方法中的阻气膜的形成被吸附在塑料容器中的水分子和具有降低气体阻挡层的容器阻碍的常规方法的问题，制造具有高阻气性的阻气膜涂覆塑料容器的方法，制造阻隔性能。该方法的特征在于包括以下步骤：减小塑料容器内部的压力或降低塑料容器的整个部分的压力，当释放真空时将干燥气体作为泄漏气体流动，以用干燥气体填充容器的内部用于干燥塑料容器，用原料气体或含原料气体的气体代替塑料容器内部的气体，并通过CVD方法在材料气体的等离子体化处理以在塑料容器的内表面上形成阻气膜。

9. 发明公开

EP1605039A4 DENDRITIC CELL PRESENTING ALPHA-GLYCOSYLCERAMIDE DERIVATIVE AND A NTIGEN AND USABLE IN SUPPRESSING IMMUNE RESPONSE 有权
标题翻译：及使用免疫反应的抑制α-糖基衍生物和抗原树突状细胞
公开(公告)号：EP1605039A4
公开(公告)日：2006-03-29
申请号：EP04716785
申请日：2004-03-03
申请人： KIRIN BREWERY
发明人： SERIZAWA ISAO , YAMAGUCHI YASUNORI , EHARA HIROMI
IPC分类号： A61K35/12 , A61P37/00 , A61P37/06 , A61P37/08 , C12N5/0784 , C12N5/06 , C12N5/08
CPC分类号： C12N5/064 , A61K2035/122 , A61K2035/124 , C12N5/0639
摘要： The present invention relates to dendritic cell and cell mixture which is capable of suppressing T cell-dependent immune response specific for an antigen. The dendritic cell according to the present invention is a dendritic cell capable of suppressing T cell-dependent immune response specific for an antigen, which presents antigen fragment of said antigen which is presented against T cell in said immune response, and alpha-glycosylceramide derivative. The cell mixture according to the present invention is a cell mixture capable of suppressing T cell-dependent immune response specific for an antigen, which comprises dendritic cells presenting at least antigen fragment of said antigen which is presented against T cell in said immune response, and dendritic cells presenting at least alpha-glycosylceramide derivative.

10. 发明公开

EP1563084A2 TRANSGENIC UNGULATES HAVING REDUCED PRION PROTEIN ACTIVITY AND USES THEREOF 审中-公开
标题翻译：具有降低朊蛋白的转基因活性的有蹄类动物及其用途
公开(公告)号：EP1563084A2
公开(公告)日：2005-08-17
申请号：EP03783271.4
申请日：2003-11-10
申请人： Hematech, LLC , KIRIN BREWERY COMPANY LTD.
发明人： ROBL, James , KUROIWA, Yoshimi , COLLAS, Philippe , SULLIVAN, Eddie , KASINATHAN, Poothappillai , TOMIZUKA, Kazuma401, RM2 Takasaki , ISHIDA, Isao352-6 Kushihashi
IPC分类号： C12P21/00 , A01K67/027 , C12N15/00 , C12N5/02 , C12N5/06 , C12N5/16
CPC分类号： C12N15/8509 , A01K67/0271 , A01K67/0276 , A01K67/0278 , A01K2207/15 , A01K2217/00 , A01K2217/05 , A01K2217/072 , A01K2227/101 , A01K2267/01 , A01K2267/02 , C07K16/00 , C07K2317/12 , C07K2317/21 , C12N2800/30
摘要： The invention provides cloned transgenic ungulates (e.g., bovines) in which prion protein activity is reduced by one or more genetically engineered mutations. Desirably, these transgenic bovines are also genetically modified to express xenogenous (e.g., human) antibodies. Because of their resistance to prion-related diseases such as bovine spongiform encephalopy (also known as mad cow disease), these bovines are a safer source of human antibodies for pharmaceutical uses and safer source of agricultural products.

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