专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

91. 发明申请

US20160329200A1 Storage Ring For Fast Processes 审中-公开
标题翻译：快速处理存储环
公开(公告)号：US20160329200A1
公开(公告)日：2016-11-10
申请号：US15107534
申请日：2014-12-18
申请人： Micromass UK Limited
发明人： Jason Lee Wildgoose
IPC分类号： H01J49/06 , H01J49/00 , G01N27/62
摘要： An ion storage device is provided which is arranged and adapted: (i) to receive first ions which have been temporally separated according to a first physico-chemical property during a first cycle of operation; (ii) to store the first ions in a first plurality of separate sections of the ion storage device so that first ions having different first physico-chemical properties are stored in different sections of the ion storage device; (iii) to receive second ions which have been temporally separated according to the first physico-chemical property during a second subsequent cycle of operation; and (iv) to store the second ions in the ion storage device so that the first and second ions are simultaneously stored within the ion storage device and so that at least some of the first and second ions having substantially the same first physico-chemical property are stored in the same section of the ion storage device.
摘要翻译：提供了一种离子存储装置，其被布置和适配：（i）在第一操作周期期间接收根据第一物理化学性质暂时分离的第一离子; （ii）将所述第一离子存储在所述离子存储装置的第一多个分离部分中，使得具有不同的第一物理化学性质的第一离子存储在所述离子存储装置的不同部分中; （iii）在第二个后续操作循环期间接收根据第一物理化学性质暂时分离的第二离子; 和（iv）将第二离子存储在离子存储装置中，使得第一和第二离子同时存储在离子存储装置内，并且使得第一和第二离子中的至少一些具有基本上相同的第一物理化学性质存储在离子存储装置的相同部分中。

92. 发明授权

US09384955B2 Mass spectrometer, control system and methods of operating and assembling a mass spectrometer 有权
标题翻译：质谱仪，控制系统和操作和组装质谱仪的方法
公开(公告)号：US09384955B2
公开(公告)日：2016-07-05
申请号：US14306269
申请日：2014-06-17
申请人： Micromass UK Limited
发明人： Phillip Edward Young , Paul Doorbar , Peter G. Spreadbury , Richard Newton , Alan McKinnon , Richard B. Moulds , Richard Chapman , Anthony J. Gilbert
IPC分类号： H01J49/02 , H01J49/00
CPC分类号： H01J49/022 , H01J49/0027 , Y10T29/49117
摘要： A mass spectrometer and methods for controlling a mass spectrometer are provided. In an exemplary embodiment, the mass spectrometer includes a plurality of discrete functional modules, each operable to perform a predetermined function of the mass spectrometer, wherein the modules are individually addressable and connected in a network. The mass spectrometer can also include a scheduler operable to introduce discrete packets of instructions to the network at predetermined times to instruct at least one module to perform a predetermined operation.
摘要翻译：提供质谱仪和控制质谱仪的方法。在示例性实施例中，质谱仪包括多个离散功能模块，每个功能模块可操作以执行质谱仪的预定功能，其中模块可单独寻址并在网络中连接。质谱仪还可以包括调度器，其可操作以在预定时间将离散指令分组引入网络，以指示至少一个模块执行预定操作。

93. 发明授权

US09383338B2 Correction of time of flight MS ADC data on push by push basis 有权
标题翻译：按推送方式校正飞行时间MS ADC数据
公开(公告)号：US09383338B2
公开(公告)日：2016-07-05
申请号：US14651929
申请日：2013-12-13
申请人： Micromass UK Limited
发明人： Martin Raymond Green , Steven Derek Pringle , Jason Lee Wildgoose , David J. Langridge
IPC分类号： G01N27/62 , H01J49/00
CPC分类号： G01N27/622 , H01J49/0009 , H01J49/0036
摘要： A method of mass spectrometry is disclosed comprising pulsing ions into a time of flight region and detecting the ions using an ion detector. The signal output from the ion detector is digitized to produce a digitized signal. The peak area A1 and arrival time T1 of the ion peak are determined and a degree to which the ion peak suffers from saturation is also determined. A corrected area A′1 of the ion peak is then determined based upon the degree to which the ion peak was determined to suffer from saturation.
摘要翻译：公开了一种质谱法，其包括将离子脉冲到飞行时间区域并使用离子检测器检测离子。从离子检测器输出的信号被数字化以产生数字化信号。确定峰面积A1和离子峰的到达时间T1，并确定离子峰饱和度的程度。然后基于离子峰被确定为饱和的程度来确定离子峰的校正区域A'1。

94. 发明授权

US09324543B2 Dynamic resolution correction of quadrupole mass analyser 有权
标题翻译：四极质量分析仪的动态分辨率校正
公开(公告)号：US09324543B2
公开(公告)日：2016-04-26
申请号：US14003176
申请日：2012-03-07
申请人： Daniel James Kenny
发明人： Daniel James Kenny
IPC分类号： H01J49/40 , H01J49/00 , H01J49/42
CPC分类号： H01J49/0009 , H01J49/0031 , H01J49/40 , H01J49/4215
摘要： A method of mass spectrometry is disclosed comprising automatically correcting the mass or mass to charge ratio resolution of a quadrupole mass filter or mass analyser one or more times during an experimental run or acquisition based upon a measurement, determination or estimation of the mass or mass to charge ratio resolution of one or more reference ions observed in a mass spectrum or mass spectral data acquired either during the same experimental run or acquisition or during a previous experimental run or acquisition.
摘要翻译：公开了一种质谱法，其包括在实验运行或获取过程中自动校正四极质量过滤器或质量分析器的质量或质量与电荷比分辨率一次或多次，基于质量或质量的测量，确定或估计，在相同的实验运行或获取期间或在之前的实验运行或采集期间获得的质谱或质谱数据中观察到的一个或多个参考离子的电荷比分辨率。

95. 发明授权

US09269554B2 Cryogenic collisional cooling cell 有权
标题翻译：低温碰撞冷却池
公开(公告)号：US09269554B2
公开(公告)日：2016-02-23
申请号：US14401156
申请日：2013-05-08
申请人： Micromass UK Limited
发明人： Jeffery Mark Brown , Jason Lee Wildgoose
IPC分类号： H01J49/04 , H01J49/00 , H01J49/40
CPC分类号： H01J49/0481 , H01J49/0031 , H01J49/401
摘要： A mass spectrometer is disclosed comprising a cooling cell for cooling ions so as to reduce their kinetic energy. The cooling cell comprises: a chamber for receiving the ions or for generating the ions therein, wherein said chamber is formed from walls defining a substantially enclosed region; and a cooling jacket surrounding said chamber, wherein said cooling jacket is arranged and configured to contain a cooling fluid and so as to remove heat from one or more walls of the chamber. The mass spectrometer further comprises a mass analyzer for receiving ions from the cooling cell after they have been cooled. The present invention reduced the kinetic energy of the ions prior to mass analysis and hence improves the resolution of the mass analyzer. The mass analyzer is preferably a time of flight mass analyzer.
摘要翻译：公开了一种质谱仪，其包括用于冷却离子以降低其动能的冷却单元。冷却单元包括：用于接收离子或用于在其中产生离子的室，其中所述室由限定基本封闭区域的壁形成; 以及围绕所述室的冷却套，其中所述冷却套被布置和构造成容纳冷却流体，以便从所述室的一个或多个壁去除热量。质谱仪还包括用于在冷却单元冷却之后从冷却单元接收离子的质量分析器。本发明在质量分析之前降低了离子的动能，因此提高了质量分析仪的分辨率。质量分析器优选为飞行时间质量分析器。

96. 发明授权

US09245728B2 Mass spectrometer with beam expander 有权
公开(公告)号：US09245728B2
公开(公告)日：2016-01-26
申请号：US14730551
申请日：2015-06-04
申请人： Micromass UK Limited
发明人： Jeffery Mark Brown , Anthony James Gilbert , John Brian Hoyes , David J. Langridge , Jason Lee Wildgoose
IPC分类号： H01J49/40 , H01J49/00 , H01J49/06
CPC分类号： H01J49/401 , H01J49/0031 , H01J49/0095 , H01J49/062 , H01J49/067 , H01J49/405
摘要： A mass spectrometer is disclosed comprising a RF confinement device, a beam expander and a Time of Flight mass analyzer. The beam expander is arranged to expand an ion beam emerging from the RF confinement device so that the ion beam is expanded to a diameter of at least 3 mm in the orthogonal acceleration extraction region of the Time of Flight mass analyzer.

97. 发明授权

US09190251B2 Pre-scan for mass to charge ratio range 有权
标题翻译：预扫描质量与充电比例范围
公开(公告)号：US09190251B2
公开(公告)日：2015-11-17
申请号：US14004520
申请日：2012-03-13
申请人： Martin Raymond Green , Jason Lee Wildgoose
发明人： Martin Raymond Green , Jason Lee Wildgoose
IPC分类号： H01J49/00
CPC分类号： H01J49/004 , H01J49/0031
摘要： A method of mass spectrometry is disclosed comprising performing a first analysis of a sample of ions wherein one or more parameters are scanned and/or ions are sorted according to one or more parameters during the first analysis. One or more ranges of interest of the one or more parameters from the first analysis are then automatically determined. A second subsequent analysis of the sample of ions is then automatically performed, wherein the second analysis is restricted to one or more of the ranges of interest of the one or more parameters.
摘要翻译：公开了一种质谱法，其包括在第一次分析期间根据一个或多个参数对离子样品进行第一次分析，其中扫描一个或多个参数和/或离子。然后自动确定来自第一次分析的一个或多个参数的一个或多个感兴趣范围。然后自动执行离子样品的第二次后续分析，其中第二分析限于一个或多个参数的一个或多个感兴趣的范围。

98. 发明授权

US09129781B2 M/Z targeted attenuation on time of flight instruments 有权
标题翻译： M / Z目标衰减飞行仪器时间
公开(公告)号：US09129781B2
公开(公告)日：2015-09-08
申请号：US14004963
申请日：2012-03-15
申请人： Keith Richardson
发明人： Keith Richardson
IPC分类号： H01J49/40 , H01J49/00
CPC分类号： H01J49/401 , H01J49/0027 , H01J49/0031 , H01J49/004 , H01J49/40
摘要： A method of mass spectrometry is disclosed comprising separating ions according to one or more physico-chemical properties. Ions which are onwardly transmitted to a Time of Flight mass analyzer are controlled by attenuating ions which would otherwise be transmitted to the Time of Flight mass analyzer and cause saturation of an ion detector and which have been determined or which are predicted to have a relatively high intensity.
摘要翻译：公开了一种质谱法，其包括根据一种或多种物理化学性质分离离子。向上传播到飞行时间质量分析器的离子通过衰减离子来控制，否则离子将否则将被传输到飞行时间质量分析器并引起离子检测器的饱和，并且已被确定或预测具有相对较高的强度。

99. 发明授权

US09111654B2 DC ion guide for analytical filtering/separation 有权
标题翻译：用于分析过滤/分离的直流离子导向器
公开(公告)号：US09111654B2
公开(公告)日：2015-08-18
申请号：US14003487
申请日：2012-03-07
申请人： Kevin Giles , Martin Raymond Green , Daniel James Kenny , David J. Langridge , Jason Lee Wildgoose
发明人： Kevin Giles , Martin Raymond Green , Daniel James Kenny , David J. Langridge , Jason Lee Wildgoose
IPC分类号： H01J49/26 , G21K1/00 , H01J49/42 , H01J49/28
CPC分类号： G21K1/00 , H01J49/062 , H01J49/28 , H01J49/427
摘要： An ion guide is disclosed comprising a plurality of electrodes. A first device is arranged and adapted to apply a RF voltage to at least some of the electrodes in order to form, in use, a pseudo-potential well which acts to confine ions in a first direction within the ion guide. A second device is arranged and adapted to apply a DC voltage to at least some of the electrodes in order to form, in use, a DC potential well which acts to confine ions in a second direction within the ion guide. A third device is arranged and adapted to cause ions having desired or undesired mass to charge ratios to be mass to charge ratio selectively ejected from the ion guide in the second direction.
摘要翻译：公开了一种离子导向器，其包括多个电极。第一装置被布置并适于将RF电压施加到至少一些电极，以在使用中形成用于将离子限制在离子导向器内的第一方向上的伪电位阱。第二装置被布置并适于将DC电压施加到至少一些电极，以在使用中形成用于在离子导向器内沿第二方向限制离子的DC势阱。第三装置被布置并适于使具有期望或不需要的质量的充电比例的离子成为从第二方向从离子导向器选择性地喷射的质荷比。

100. 发明授权

US09080936B2 Glow discharge ion source 有权
标题翻译：辉光放电离子源
公开(公告)号：US09080936B2
公开(公告)日：2015-07-14
申请号：US13055612
申请日：2009-07-27
申请人： Jeffery Mark Brown , Martin Raymond Green , Steven Derek Pringle
发明人： Jeffery Mark Brown , Martin Raymond Green , Steven Derek Pringle
IPC分类号： G01N24/00 , H01J49/00 , H01J49/10 , H01J49/12 , H01J49/16 , H01J49/04
CPC分类号： H01J49/12 , G01N24/00 , H01J49/0009 , H01J49/0072 , H01J49/0495 , H01J49/107 , H01J49/165 , Y10T436/24
摘要： A mass spectrometer is disclosed comprising a glow discharge device within the initial vacuum chamber of the mass spectrometer. The glow discharge device may comprise a tubular electrode (14) located within an isolation valve (15) which is provided in the vacuum chamber. Reagent vapor may be provided through the tubular electrode (14) which is then subsequently ionized by the glow discharge. The resulting reagent ions may be used for Electron Transfer Dissociation of analyte ions generated by an atmospheric pressure ion source. Other embodiments are contemplated wherein the ions generated by the glow discharge device may be used to reduce the charge state of analyte ions by Proton Transfer Reaction or may act as lock mass or reference ions.
摘要翻译：公开了质谱仪，其包括在质谱仪的初始真空室内的辉光放电装置。辉光放电装置可以包括设置在真空室中的隔离阀（15）内的管状电极（14）。可以通过管状电极（14）提供试剂蒸汽，然后其随后通过辉光放电电离。所得的试剂离子可用于由大气压离子源产生的分析物离子的电子转移离解。考虑其他实施例，其中由辉光放电装置产生的离子可用于通过质子转移反应来减少分析物离子的电荷状态，或者可以作为锁定质量或参考离子。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式